1. Boston University

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    1. Mentioned In 62 Articles

    2. Improving graph-based OCT segmentation for severe pathology in retinitis pigmentosa patients

      Improving graph-based OCT segmentation for severe pathology in retinitis pigmentosa patients
      Three dimensional segmentation of macular optical coherence tomography (OCT) data of subjects with retinitis pigmentosa (RP) is a challenging problem due to the disappearance of the photoreceptor layers, which causes algorithms developed for segmentation of healthy data to perform poorly on RP patients. In this work, we present enhancements to a previously developed graph-based OCT segmentation pipeline to enable processing of RP data. The algorithm segments eight retinal layers in ...
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    3. Optical coherence tomography for non-invasive examination and conservation of cultural heritage objects

      Optical coherence tomography for non-invasive examination and conservation of cultural heritage objects
      Optical coherence tomography (OCT) has great potential for the examination of oil paintings, particularly for celebrated masterpieces by great artists in history. We developed an OCT system for large field of view (FOV), high definition (HD) imaging of oil paintings. To achieve large FOV, we translated the sample using a pair of high-precision linear motors and performed sequential volumetric imaging on adjacent, non-overlapping regions. Through 3D OCT imaging, the surface ...
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    4. High-definition optical coherence tomography imaging for noninvasive examination of heritage works

      High-definition optical coherence tomography imaging for noninvasive examination of heritage works
      Cultural heritage works, such as ancient murals and historical paintings, are examined routinely for the purpose of conservation. Previous works have applied optical coherence tomography (OCT), which is a three-dimensional (3D) microscopic imaging modality in the field of heritage works conservation. The data acquired by OCT provides both 3D surface information of the object and structure information underneath the surface. Therefore, cross-sectional information on the object can be utilized to ...
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    5. Dual-band optical coherence tomography using a single supercontinuum laser source

      Dual-band optical coherence tomography using a single supercontinuum laser source
      We developed a simultaneous visible-light (Vis) and near-infrared (NIR) dual-band optical coherence tomography (OCT) system using a single supercontinuum laser source. The goal was to benchmark our newly developed Vis-OCT against the well-developed NIR-OCT. The Vis-OCT subsystem operated at 91 nm full-width-at-half-maximum (FWHM) bandwidth centered at 566 nm; the NIR-OCT subsystem operated at 93 nm FWHM bandwidth centered at 841 nm. The axial resolutions were 1.8 and 4.4 ...
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    6. Postdoctoral positions open at Boston University School of Medicine

      Postdoctoral positions open at Boston University School of Medicine
      The research is to design, manufacture optical devises, develop novel optical theory and methods for biomedical and clinical applications. The desired experience or interest includes but not limited: light scattering theory, light-tissue interaction, optics design and instrumentation, precision instrumentation, electronics design, programming, fiber optics and endoscopy. Candidate should have PhD degree in physics, optical engineering, biomedical engineering, electronic engineering, mechanical engineering or equivalent training background. Please directly contact PI at ...
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    7. Boston University Receives NIH Grant for Visualizing Cortical Microstructures by Optical Coherence Tomography

      Boston University Receives NIH Grant for Visualizing Cortical Microstructures by Optical Coherence Tomography
      ... imaging (at Massachusetts General Hospital) with expertise in cell type and microstructure analysis (MGH and Boston University School of Medicine). Success will be defined as determining that histological populations ar...
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    8. UV-VIS Spectroscopy in the Clinic – What’s Stopping It?

      UV-VIS Spectroscopy in the Clinic – What’s Stopping It?
      Bigios team isnt the only one to encounter this difficulty in attracting funding. Dr. Adam Waxs group at Duke University has been developing a technique angle-resolved low-coherence interferometry, or a/LCI enabling early detection of cancer and other biomedical applications by measuring the average size of cell nuclei using scattered light. The focus of the a/LCI instrument has been Barretts esophagus, a precursor to esophageal cancer. But Wax is ...
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    9. Dual modality intravascular optical coherence tomography (OCT) and near-infrared fluorescence (NIRF) imaging: a fully automated algorithm for the distance-calibration of NIRF signal intensity for quantitative molecular imaging

      Dual modality intravascular optical coherence tomography (OCT) and near-infrared fluorescence (NIRF) imaging: a fully automated algorithm for the distance-calibration of NIRF signal intensity for quantitative molecular imaging
      ...ardiology, University Medical Center Utrecht, Utrecht, The Netherlands Department of Biomedical Engineering, Boston University, Boston, MA, USA Cardiology Division, Beth Israel Deaconess Medical Center, Boston, MA, USA...
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    10. Label-free evaluation of angiogenic sprouting in microengineered devices using ultrahigh-resolution optical coherence microscopy

      Label-free evaluation of angiogenic sprouting in microengineered devices using ultrahigh-resolution optical coherence microscopy
      ...nnsylvania 19104 University of Pennsylvania, Department of Bioengineering, Philadelphia, Pennsylvania 19104 Boston University, Department of Biomedical Engineering, Boston, Massachusetts 02115 Harvard University, Wyss...
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    11. Optical coherence tomography – near infrared spectroscopy system and catheter for intravascular imaging

      Optical coherence tomography – near infrared spectroscopy system and catheter for intravascular imaging
      Owing to its superior resolution, intravascular optical coherence tomography (IVOCT) is a promising tool for imaging the microstructure of coronary artery walls. However, IVOCT does not identify chemicals and molecules in the tissue, which is required for a more complete understanding and accurate diagnosis of coronary disease. Here we present a dual-modality imaging system and catheter that uniquely combines IVOCT with diffuse near-infrared spectroscopy (NIRS) in a single dual-modality imaging ...
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  2. About Boston University

    Boston University

    Boston University (BU) is a private research university located in Boston, Massachusetts, United States. With more than 3,000 faculty members and nearly 30,000 students, Boston University is the fourth-largest private university in the United States of America.  Boston University Medical Campus (BUMC) is located in the historic South End of Boston and comprises the Boston University School of Medicine, the Boston University School of Public Health, the Goldman School of Dental Medicine, and the Boston University Graduate School of Medical Sciences. Boston Medical Center is a private, not for profit, 581-licensed bed academic medical center located in Boston's historic South End. The hospital is the primary teaching affiliate for Boston University School of Medicine. Emphasizing community-based care, Boston Medical Center with its mission to provide consistently accessible health services to all is the largest safety net hospital in New England.