1. Boston University

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    1. Mentioned In 96 Articles

    2. Visible light optical coherence tomography angiography (vis-OCTA) facilitates local microvascular oximetry in the human retina

      Explore OSA | OSA Publishing Ophthalmology
      Visible light optical coherence tomography angiography (vis-OCTA) facilitates local microvascular oximetry in the human retina
      We report herein the first visible light optical coherence tomography angiography (vis-OCTA) for human retinal imaging. Compared to the existing vis-OCT systems, we devised a spectrometer with a narrower bandwidth to increase the spectral power density for OCTA imaging, while retaining the major spectral contrast in the blood. We achieved a 100 kHz A-line rate, the fastest acquisition speed reported so far for human retinal vis-OCT. We rigorously optimized the ...
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      Mentions: Northwestern University Boston University Ji Yi

    3. Comparison of widefield swept-source optical coherence tomography angiography with ultra-widefield colour fundus photography and fluorescein angiography for detection of lesions in diabetic retinopathy

      Explore BJO Online Ophthalmology
      Comparison of widefield swept-source optical coherence tomography angiography with ultra-widefield colour fundus photography and fluorescein angiography for detection of lesions in diabetic retinopathy
      Aims To compare widefield swept-source optical coherence tomography angiography (WF SS-OCTA) with ultra-widefield colour fundus photography (UWF CFP) and fluorescein angiography (UWF FA) for detecting diabetic retinopathy (DR) lesions. Methods This prospective, observational study was conducted at Massachusetts Eye and Ear from December 2018 to October 2019. Proliferative DR, non-proliferative DR and diabetic patients with no DR were included. All patients were imaged with a WF SS-OCTA using a Montage ...
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      Mentions: Johns Hopkins University Harvard University Boston University

    4. Visible light optical coherence tomography angiography (vis-OCTA)

      Explore bioRxiv.org Ophthalmology
      Visible light optical coherence tomography angiography (vis-OCTA)
      We report herein the first visible light optical coherence tomography angiography (vis-OCTA) for human retinal imaging. Compared to the existing vis-OCT systems, we devised a spectrometer with a narrower bandwidth to increase the spectral power density for OCTA imaging, while retaining the major spectral contrast in the blood. We achieved a 100 kHz A-line rate, the fastest acquisition speed reported so far for human retinal vis-OCT. We rigorously optimized the ...
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      Mentions: Northwestern University Boston University

    5. Insight into the fundamental trade-offs of diffusion MRI from polarization-sensitive optical coherence tomography in ex vivo human brain

      Explore ScienceDirect Neurology
      Insight into the fundamental trade-offs of diffusion MRI from polarization-sensitive optical coherence tomography in ex vivo human brain
      In the first study comparing high angular resolution diffusion MRI (dMRI) in the human brain to axonal orientation measurements from polarization-sensitive optical coherence tomography (PSOCT), we compare the accuracy of orientation estimates from various dMRI sampling schemes and reconstruction methods. We find that, if the reconstruction approach is chosen carefully, single-shell dMRI data can yield the same accuracy as multi-shell data, and only moderately lower accuracy than a full Cartesian-grid ...
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      Mentions: Massachusetts General Hospital Harvard University Boston University

    7. Special Section Guest Editorial: Advances in Retinal Imaging

      Explore SPIE Digital Library Ophthalmology
      Special Section Guest Editorial: Advances in Retinal Imaging
      The guest editorial provides an introduction to the Special Section on Advanced Retinal Imaging: Instrumentation, Methods, and Applications. The retina is a peripheral part of the central nerve system (CNS) and shares many similarities with the cerebral cortex. They both have layered anatomy, the same types of functional elements and neurotransmitters, and similar vascular organization and blood-tissue barriers. With far fewer neuronal cell types and simpler anatomical structures, the retina ...
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      Mentions: Duke University Stanford University Boston University

    8. Optical coherence tomography using physical domain data compression to achieve MHz A-scan rates

      Explore OSA | OSA Publishing
      Optical coherence tomography using physical domain data compression to achieve MHz A-scan rates
      The three-dimensional volumetric imaging capability of optical coherence tomography (OCT) leads to the generation of large amounts of data, which necessitates high speed acquisition followed by high dimensional image processing and visualization. This signal acquisition and processing pipeline demands high A-scan rates on the front end, which has driven researchers to push A-scan acquisition rates into the MHz regime. To this end, the optical time-stretch approach uses a mode locked ...
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      Mentions: Johns Hopkins University Boston University

    9. Deep spectral learning for label-free optical imaging oximetry with uncertainty quantification

      Explore Nature Publishing Group
      Deep spectral learning for label-free optical imaging oximetry with uncertainty quantification
      Measurement of blood oxygen saturation ( s O 2 ) by optical imaging oximetry provides invaluable insight into local tissue functions and metabolism. Despite different embodiments and modalities, all label-free optical-imaging oximetry techniques utilize the same principle of s O 2 -dependent spectral contrast from haemoglobin. Traditional approaches for quantifying s O 2 often rely on analytical models that are fitted by the spectral measurements. These approaches in practice suffer from uncertainties ...
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      Mentions: Boston University Ji Yi

    11. MATLAB code and data processing guide for Dynamic Light Scattering-Optical Coherence Tomography

      Explore OpenBU
      MATLAB code and data processing guide for Dynamic Light Scattering-Optical Coherence Tomography
      This guide is for post data processing of DLSOCT, which outputs axial velocity (Vz), transverse velocity (Vx), total velocity(V), the ratio of static component (Ms), the ratio of dynamic component (Mf), and fitting accuracy (R). The speed upper limit is determined by OCT system Aline rate and 3Dvoxel size.
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      Mentions: Boston University David A. Boas

    12. Massachusetts General Hospital Receives NIH Grant for Assessing Airway Smooth Muscle Tone in Asthma with Endobroncial Optical Coherence Tomography

      Explore Optical Coherence Tomography News Pulmonology , Funding
      Massachusetts General Hospital Receives NIH Grant for Assessing Airway Smooth Muscle Tone in Asthma with Endobroncial Optical Coherence Tomography
      ...e of the key progenitors of OCT technology and translational OCT. Dr. Kenneth Lutchen, a secondary mentor, of Boston University is a pioneer in the development of experiments aimed at investigating lung physiology, and s...
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      Mentions: Brett E. Bouma National Institutes of Health Massachusetts General Hospital

    13. Longitudinal detection of retinal alterations by visible and near-infrared optical coherence tomography in a dexamethasone-induced ocular hypertension mouse model

      Explore SPIE Digital Library Ophthalmology
      Longitudinal detection of retinal alterations by visible and near-infrared optical coherence tomography in a dexamethasone-induced ocular hypertension mouse model
      The retina, as part of the central nervous system, has distinct anatomical and structural properties for its visual function. Light scattering spectroscopy, while widely used for tissue structural characterization and disease diagnosis, has been relatively unexplored in the living retina. Recently, we have developed a fiber-based visible and near-infrared optical coherence tomography system (vnOCT) for in vivo retinal imaging, to uniquely measure a spectroscopic marker (VN ratio) sensitive to nanoscale ...
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      Mentions: Boston University Ji Yi
    17. 1-15 of 96 1 2 3 4 5 6 7 »
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  4. About Boston University

    Boston University

    Boston University (BU) is a private research university located in Boston, Massachusetts, United States. With more than 3,000 faculty members and nearly 30,000 students, Boston University is the fourth-largest private university in the United States of America.  Boston University Medical Campus (BUMC) is located in the historic South End of Boston and comprises the Boston University School of Medicine, the Boston University School of Public Health, the Goldman School of Dental Medicine, and the Boston University Graduate School of Medical Sciences. Boston Medical Center is a private, not for profit, 581-licensed bed academic medical center located in Boston's historic South End. The hospital is the primary teaching affiliate for Boston University School of Medicine. Emphasizing community-based care, Boston Medical Center with its mission to provide consistently accessible health services to all is the largest safety net hospital in New England.

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