1. Boston University

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    1. Mentioned In 64 Articles

    3. Oblique scanning laser microscopy for simultaneously volumetric structural and molecular imaging using only one raster scan

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      Oblique scanning laser microscopy for simultaneously volumetric structural and molecular imaging using only one raster scan
      Multi-modal three dimensional (3D) optical imaging combining both structural sensitivity and molecular specificity is highly desirable in biomedical research. In this paper, we present a method termed oblique scanning laser microscopy (OSLM) to combine optical coherence tomography (OCT), for simultaneously volumetric structural and molecular imaging with cellular resolution in all three dimensions. Conventional 3D laser scanning fluorescence microscopy requires repeated optical sectioning to create z-stacks in depth. Here, the use ...
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      Mentions: Boston University Ji Yi

    4. Improving graph-based OCT segmentation for severe pathology in retinitis pigmentosa patients

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      Improving graph-based OCT segmentation for severe pathology in retinitis pigmentosa patients
      Three dimensional segmentation of macular optical coherence tomography (OCT) data of subjects with retinitis pigmentosa (RP) is a challenging problem due to the disappearance of the photoreceptor layers, which causes algorithms developed for segmentation of healthy data to perform poorly on RP patients. In this work, we present enhancements to a previously developed graph-based OCT segmentation pipeline to enable processing of RP data. The algorithm segments eight retinal layers in ...
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      Mentions: Johns Hopkins University Boston University

    5. Optical coherence tomography for non-invasive examination and conservation of cultural heritage objects

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      Optical coherence tomography for non-invasive examination and conservation of cultural heritage objects
      Optical coherence tomography (OCT) has great potential for the examination of oil paintings, particularly for celebrated masterpieces by great artists in history. We developed an OCT system for large field of view (FOV), high definition (HD) imaging of oil paintings. To achieve large FOV, we translated the sample using a pair of high-precision linear motors and performed sequential volumetric imaging on adjacent, non-overlapping regions. Through 3D OCT imaging, the surface ...
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      Mentions: Boston University Xuan Liu Yi Yang

    6. High-definition optical coherence tomography imaging for noninvasive examination of heritage works

      Explore OSA | OSA Publishing Art
      High-definition optical coherence tomography imaging for noninvasive examination of heritage works
      Cultural heritage works, such as ancient murals and historical paintings, are examined routinely for the purpose of conservation. Previous works have applied optical coherence tomography (OCT), which is a three-dimensional (3D) microscopic imaging modality in the field of heritage works conservation. The data acquired by OCT provides both 3D surface information of the object and structure information underneath the surface. Therefore, cross-sectional information on the object can be utilized to ...
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      Mentions: Boston University Xuan Liu Yi Yang

    8. Dual-band optical coherence tomography using a single supercontinuum laser source

      Explore SPIE | Journal
      Dual-band optical coherence tomography using a single supercontinuum laser source
      We developed a simultaneous visible-light (Vis) and near-infrared (NIR) dual-band optical coherence tomography (OCT) system using a single supercontinuum laser source. The goal was to benchmark our newly developed Vis-OCT against the well-developed NIR-OCT. The Vis-OCT subsystem operated at 91 nm full-width-at-half-maximum (FWHM) bandwidth centered at 566 nm; the NIR-OCT subsystem operated at 93 nm FWHM bandwidth centered at 841 nm. The axial resolutions were 1.8 and 4.4 ...
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      Mentions: Northwestern University Boston University Ji Yi

    9. Postdoctoral positions open at Boston University School of Medicine

      Explore Optical Coherence Tomography News Jobs & Studentships
      Postdoctoral positions open at Boston University School of Medicine
      The research is to design, manufacture optical devises, develop novel optical theory and methods for biomedical and clinical applications. The desired experience or interest includes but not limited: light scattering theory, light-tissue interaction, optics design and instrumentation, precision instrumentation, electronics design, programming, fiber optics and endoscopy. Candidate should have PhD degree in physics, optical engineering, biomedical engineering, electronic engineering, mechanical engineering or equivalent training background. Please directly contact PI at ...
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      Mentions: Boston University Ji Yi

    11. Boston University Receives NIH Grant for Visualizing Cortical Microstructures by Optical Coherence Tomography

      Explore Optical Coherence Tomography News Neurology , Funding
      Boston University Receives NIH Grant for Visualizing Cortical Microstructures by Optical Coherence Tomography
      ... imaging (at Massachusetts General Hospital) with expertise in cell type and microstructure analysis (MGH and Boston University School of Medicine). Success will be defined as determining that histological populations ar...
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      Mentions: National Institutes of Health Massachusetts General Hospital Boston University

    14. UV-VIS Spectroscopy in the Clinic – What’s Stopping It?

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      UV-VIS Spectroscopy in the Clinic – What’s Stopping It?
      Bigios team isnt the only one to encounter this difficulty in attracting funding. Dr. Adam Waxs group at Duke University has been developing a technique angle-resolved low-coherence interferometry, or a/LCI enabling early detection of cancer and other biomedical applications by measuring the average size of cell nuclei using scattered light. The focus of the a/LCI instrument has been Barretts esophagus, a precursor to esophageal cancer. But Wax is ...
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      Mentions: Duke University Adam Wax Boston University

    15. Dual modality intravascular optical coherence tomography (OCT) and near-infrared fluorescence (NIRF) imaging: a fully automated algorithm for the distance-calibration of NIRF signal intensity for quantitative molecular imaging

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      Dual modality intravascular optical coherence tomography (OCT) and near-infrared fluorescence (NIRF) imaging: a fully automated algorithm for the distance-calibration of NIRF signal intensity for quantitative molecular imaging
      ...ardiology, University Medical Center Utrecht, Utrecht, The Netherlands Department of Biomedical Engineering, Boston University, Boston, MA, USA Cardiology Division, Beth Israel Deaconess Medical Center, Boston, MA, USA...
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      Mentions: Guillermo J. Tearney Beth Israel Deaconess Medical Center Massachusetts Institute of Technology

    16. Label-free evaluation of angiogenic sprouting in microengineered devices using ultrahigh-resolution optical coherence microscopy

      Explore SPIE | Journal Microscopy
      Label-free evaluation of angiogenic sprouting in microengineered devices using ultrahigh-resolution optical coherence microscopy
      ...nnsylvania 19104 University of Pennsylvania, Department of Bioengineering, Philadelphia, Pennsylvania 19104 Boston University, Department of Biomedical Engineering, Boston, Massachusetts 02115 Harvard University, Wyss...
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      Mentions: Lehigh University University of Pennsylvania Harvard University
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  4. About Boston University

    Boston University

    Boston University (BU) is a private research university located in Boston, Massachusetts, United States. With more than 3,000 faculty members and nearly 30,000 students, Boston University is the fourth-largest private university in the United States of America.  Boston University Medical Campus (BUMC) is located in the historic South End of Boston and comprises the Boston University School of Medicine, the Boston University School of Public Health, the Goldman School of Dental Medicine, and the Boston University Graduate School of Medical Sciences. Boston Medical Center is a private, not for profit, 581-licensed bed academic medical center located in Boston's historic South End. The hospital is the primary teaching affiliate for Boston University School of Medicine. Emphasizing community-based care, Boston Medical Center with its mission to provide consistently accessible health services to all is the largest safety net hospital in New England.

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