1. Boston University

    0 Comments Leave a Comment

    1-15 of 117 1 2 3 4 5 6 7 8 »

    1. Mentioned In 117 Articles

    2. Visible Light Optical Coherence Tomography of Peripapillary Retinal Nerve Fiber Layer Reflectivity in Glaucoma

      Explore TVST Journal Ophthalmology
      Visible Light Optical Coherence Tomography of Peripapillary Retinal Nerve Fiber Layer Reflectivity in Glaucoma
      Purpose: To evaluate the clinical utility of visible light optical coherence tomography (VIS-OCT) and to test whether VIS-OCT reflectivity and spectroscopy of peripapillary retinal nerve fiber layer (pRNFL) are correlated with severity of glaucoma, compared with standard-of-care OCT thickness measurements. Methods: In total 54 eyes (20 normal, 17 suspect/preperimetric glaucoma [GS/PPG], 17 perimetric glaucoma [PG]) were successfully imaged with complete datasets. All the eyes were scanned by a ...
      Read Full Article
      Mentions: Johns Hopkins University Boston University

    3. Optical coherence tomography holds promise to transform the diagnostic anatomic pathology gross evaluation process

      Explore SPIE Digital Library
      Optical coherence tomography holds promise to transform the diagnostic anatomic pathology gross evaluation process
      Significance : Real-time histology can close a variety of gaps in tissue diagnostics. Currently, gross pathology analysis of excised tissue is dependent upon visual inspection and palpation to identify regions of interest for histopathological processing. Such analysis is limited by the variable correlation between macroscopic and microscopic findings. The current standard of care is costly, burdensome, and inefficient. Aim : We are the first to address this gap by introducing optical coherence ...
      Read Full Article
      Mentions: Columbia University Boston University

    4. Reproducibility of Neuroretinal Rim Measurements Obtained from High-Density Spectral Domain Optical Coherence Tomography Volume Scans

      Explore Medical Journals Publisher Ophthalmology
      Reproducibility of Neuroretinal Rim Measurements Obtained from High-Density Spectral Domain Optical Coherence Tomography Volume Scans
      Purpose: To compare the reproducibility of two-dimensional (2D) peripapillary retinal nerve fiber layer (RNFL) thickness and three-dimensional (3D) neuroretinal rim measurements using spectral domain optical coherence tomography (SDOCT) in normal and glaucoma subjects. Methods: One eye per subject for 27 normal and 40 glaucoma subjects underwent repeat SDOCT RNFL thickness scans and optic nerve volume scans on the same day. From the volume scan, custom software calculated five neuroretinal rim ...
      Read Full Article
      Mentions: University of Florida Columbia University Harvard University

    5. Massachusetts General Hosptial Receives NIH Grant for Assessing Airway Smooth Muscle Tone in Asthma with Endobronchial Optical Coherence Tomography

      Explore Optical Coherence Tomography News Pulmonology , Funding
      Massachusetts General Hosptial Receives NIH Grant for Assessing Airway Smooth Muscle Tone in Asthma with Endobronchial Optical Coherence Tomography
      ...e of the key progenitors of OCT technology and translational OCT. Dr. Kenneth Lutchen, a secondary mentor, of Boston University is a pioneer in the development of experiments aimed at investigating lung physiology, and s...
      Read Full Article
      Mentions: National Institutes of Health Massachusetts General Hospital Harvard University

    6. Pilot Study of Biopsy Scanner for Evaluation of Bronchoscopic Small Biopsy Specimens to Determine Adequacy

      Explore Home - ClinicalTrials.gov Microscopy , Pulmonology , Clinical Trials
      Pilot Study of Biopsy Scanner for Evaluation of Bronchoscopic Small Biopsy Specimens to Determine Adequacy
      In this study, lymph node or lung nodule tissue will be collected by bronchoscopy as part of standard clinical care. The tissue is being collected to help make a diagnosis of a pulmonary condition. The same amount of tissue that is collected per standard of care for diagnosis will be collected during the study; no additional tissue is taken for this study. The biopsy sample will be analyzed by the ...
      Read Full Article
      Mentions: National Institutes of Health Boston University Aquyre Biosciences

    7. A novel algorithm for multiplicative speckle noise reduction in ex vivo human brain OCT images

      Explore ScienceDirect Neurology
      A novel algorithm for multiplicative speckle noise reduction in ex vivo human brain OCT images
      Optical coherence tomography (OCT) images of ex vivo human brain tissue are corrupted by multiplicative speckle noise that degrades the contrast to noise ratio (CNR) of microstructural compartments. This work proposes a novel algorithm to reduce noise corruption in OCT images that minimizes the penalized negative log likelihood of gamma distributed speckle noise. The proposed method is formulated as a majorize-minimize problem that reduces to solving an iterative regularized least ...
      Read Full Article
      Mentions: Massachusetts Institute of Technology Massachusetts General Hospital Harvard University

    8. Volumetric characterization of microvasculature in ex vivo human brain samples by serial sectioning optical coherence tomography

      Explore IEEE Xplore Neurology
      Volumetric characterization of microvasculature in ex vivo human brain samples by serial sectioning optical coherence tomography
      Objective: Serial sectioning optical coherence tomography (OCT) enables distortion-free volumetric reconstruction of several cubic centimeters of human brain samples. We aimed to identify anatomical features of the ex vivo human brain, such as intraparenchymal blood vessels and axonal fiber bundles, from the OCT data in 3D, using intrinsic optical contrast. Methods: We developed an automatic processing pipeline to enable characterization of the intraparenchymal microvascular network in human brain samples. Results ...
      Read Full Article
      Mentions: Massachusetts General Hospital Boston University The Chinese University of Hong Kong

    9. Soft-Tissue Material Properties and Mechanogenetics during Cardiovascular Development

      Explore MDPI Open Access Journals Platform Cardiology , Developmental Biology
      Soft-Tissue Material Properties and Mechanogenetics during Cardiovascular Development
      During embryonic development, changes in the cardiovascular microstructure and material properties are essential for an integrated biomechanical understanding. This knowledge also enables realistic predictive computational tools, specifically targeting the formation of congenital heart defects. Material characterization of cardiovascular embryonic tissue at consequent embryonic stages is critical to understand growth, remodeling, and hemodynamic functions. Two biomechanical loading modes, which are wall shear stress and blood pressure, are associated with distinct molecular ...
      Read Full Article
      Mentions: Imperial College London Boston University

    10. Refractive-index matching enhanced polarization sensitive optical coherence tomography quantification in human brain tissue

      Explore Optica Publishing Group Neurology
      Refractive-index matching enhanced polarization sensitive optical coherence tomography quantification in human brain tissue
      The importance of polarization-sensitive optical coherence tomography (PS-OCT) has been increasingly recognized in human brain imaging. Despite the recent progress of PS-OCT in revealing white matter architecture and orientation, quantification of fine-scale fiber tracts in the human brain cortex has been a challenging problem, due to a low birefringence in the gray matter. In this study, we investigated the effect of refractive index matching by 2,2-thiodiethanol (TDE) immersion on ...
      Read Full Article
      Mentions: Massachusetts Institute of Technology Massachusetts General Hospital Harvard University

    11. Scalable mapping of myelin and neuron density in the human brain with micrometer resolution

      Explore Nature Publishing Group Neurology
      Scalable mapping of myelin and neuron density in the human brain with micrometer resolution
      Optical coherence tomography (OCT) is an emerging 3D imaging technique that allows quantification of intrinsic optical properties such as scattering coefficient and back-scattering coefficient, and has proved useful in distinguishing delicate microstructures in the human brain. The origins of scattering in brain tissues are contributed by the myelin content, neuron size and density primarily; however, no quantitative relationships between them have been reported, which hampers the use of OCT in ...
      Read Full Article
      Mentions: Massachusetts General Hospital Boston University

    12. Simultaneous visible light optical coherence tomography and near infrared OCT angiography in retinal pathologies: A case study

      Explore SAGE Journals Ophthalmology
      Simultaneous visible light optical coherence tomography and near infrared OCT angiography in retinal pathologies: A case study
      A dual-channel optical coherence tomography system with wavelengths in the visible and near-infrared light ranges can provide both structural and functional information for retinal microvasculature simultaneously. We applied this integrated system in an ongoing clinical study of patients with various retinal pathologies. Here, we present case study results of patients with diabetic retinopathy, central retinal vein occlusion, and sickle cell retinopathy compared to a healthy subject. For the first time ...
      Read Full Article
      Mentions: Johns Hopkins University Boston University

    13. Refractive-index matching enhanced polarization-sensitive optical coherence tomography quantification in human brain tissue

      Explore bioRxiv.org Neurology
      Refractive-index matching enhanced polarization-sensitive optical coherence tomography quantification in human brain tissue
      The importance of polarization-sensitive optical coherence tomography (PS-OCT) has been increasingly recognized in human brain imaging. Despite the recent progress of PS-OCT in revealing white matter architecture and orientation, quantification of fine-scale fiber tracts in the human brain cortex has been a challenging problem, due to a low birefringence in the gray matter. In this study, we investigated the effect of refractive index matching by 2,2'-thiodiethanol (TDE) immersion ...
      Read Full Article
      Mentions: Massachusetts Institute of Technology Massachusetts General Hospital Harvard University

    14. MGH Receives NIH Grant for Assessing Airway Smooth Muscle Tone in Asthma with Endobronchial Optical Coherence Tomography

      Explore Optical Coherence Tomography News Pulmonology , Funding
      MGH Receives NIH Grant for Assessing Airway Smooth Muscle Tone in Asthma with Endobronchial Optical Coherence Tomography
      ...e of the key progenitors of OCT technology and translational OCT. Dr. Kenneth Lutchen, a secondary mentor, of Boston University is a pioneer in the development of experiments aimed at investigating lung physiology, and s...
      Read Full Article
      Mentions: National Institutes of Health Massachusetts General Hospital Harvard University

    15. Deep Learning in Biomedical Optics

      Explore Wiley Online Library
      Deep Learning in Biomedical Optics
      This article reviews deep learning applications in biomedical optics with a particular emphasis on image formation. The review is organized by imaging domains within biomedical optics and includes microscopy, fluorescence lifetime imaging, in vivo microscopy, widefield endoscopy, optical coherence tomography, photoacoustic imaging, diffuse tomography, and functional optical brain imaging. For each of these domains, we summarize how deep learning has been applied and highlight methods by which deep learning can ...
      Read Full Article
      Mentions: Johns Hopkins University Boston University

    16. Scalable mapping of myelin and neuron density in the human brain with micrometer resolution

      Explore bioRxiv.org Neurology
      Scalable mapping of myelin and neuron density in the human brain with micrometer resolution
      Optical Coherence Tomography (OCT) is an emerging 3D imaging technique that allows quantification of intrinsic optical properties such as scattering coefficient and back-scattering coefficient, and has proved useful in distinguishing delicate microstructures in the human brain. The origins of scattering in brain tissues are contributed by the myelin content, neuron size and density primarily; however, no quantitative relationships between them have been reported, which hampers the use of OCT in ...
      Read Full Article
      Mentions: Massachusetts General Hospital Boston University
    17. 1-15 of 117 1 2 3 4 5 6 7 8 »
  1. Search:

  2. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology

    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents

    3. Technology:

      Broadband Sources, Probes, Tunable Sources

    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks

  4. About Boston University

    Boston University

    Boston University (BU) is a private research university located in Boston, Massachusetts, United States. With more than 3,000 faculty members and nearly 30,000 students, Boston University is the fourth-largest private university in the United States of America.  Boston University Medical Campus (BUMC) is located in the historic South End of Boston and comprises the Boston University School of Medicine, the Boston University School of Public Health, the Goldman School of Dental Medicine, and the Boston University Graduate School of Medical Sciences. Boston Medical Center is a private, not for profit, 581-licensed bed academic medical center located in Boston's historic South End. The hospital is the primary teaching affiliate for Boston University School of Medicine. Emphasizing community-based care, Boston Medical Center with its mission to provide consistently accessible health services to all is the largest safety net hospital in New England.

  5. Related Topics

    1. Imaging technologies take charge in the war on cancer
      33 articles also mentioned Massachusetts General Hospital
    2. Location, Location—Innovation: Companies in key U.S. regions continue to dominate medtech innovation, but the names on their patents often come with overseas addresses.
      28 articles also mentioned Harvard University
    3. The Year in Stimulus Funding: The impact of the American Recovery and Reinvestment Act on biomedical research
      16 articles also mentioned National Institutes of Health
    4. Spectral Domain Optical Coherence Tomography for Quantitative Evaluation of Drusen and Associated Structural Changes in Non-Neovascular Age Related Macular Degeneration
      8 articles also mentioned Carl Zeiss Meditec
    5. Thinking inside the graft: applications of optical coherence tomography in coronary artery bypass grafting
      7 articles also mentioned Abbott
    6. Improving graph-based OCT segmentation for severe pathology in retinitis pigmentosa patients
      6 articles also mentioned Johns Hopkins University