1. Boris Považay

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    1. Mentioned In 54 Articles

    2. Selective retina therapy enhanced with optical coherence tomography for dosimetry control and monitoring: a proof of concept study

      Selective retina therapy enhanced with optical coherence tomography for dosimetry control and monitoring: a proof of concept study
      Selective treatment of the retinal pigment epithelium (RPE) by using short-pulse lasers leads to a less destructive treatment for certain retinal diseases in contrast to conventional photocoagulation. The introduction of selective retina therapy (SRT) to clinical routine is still precluded by the challenges to reliably monitor treatment success and to automatically adjust dose within the locally varying therapeutic window. Combining micrometer-scale depth resolving capabilities of optical coherence tomography (OCT) with ...
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    3. Time-Resolved Ultra–High Resolution Optical Coherence Tomography for Real-Time Monitoring of Selective Retina Therapy

      Time-Resolved Ultra–High Resolution Optical Coherence Tomography for Real-Time Monitoring of Selective Retina Therapy
      Purpose : Selective retina therapy (SRT) is a novel treatment for retinal pathologies, solely targeting the RPE. During SRT, the detection of an immediate tissue reaction is challenging, as tissue effects remain limited to intracellular RPE photodisruption. Time-resolved ultra-high axial resolution optical coherence tomography (OCT) is thus evaluated for the monitoring of dynamic optical changes at and around the RPE during SRT. Methods : An experimental OCT system with an ultra-high axial ...
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    4. Real-time optical coherence tomography observation of retinal tissue damage during laser photocoagulation therapy on ex-vivo porcine samples

      Real-time optical coherence tomography observation of retinal tissue damage during laser photocoagulation therapy on ex-vivo porcine samples
      Retinal laser photocoagulation represents a widely used treatment for retinal pathologies such as diabetic chorioretinopathy or diabetic edema. For effective treatment, an appropriate choice of the treatment energy dose is crucial to prevent excessive tissue damage caused by over-irradiation of the retina. In this manuscript we investigate simultaneous and time-resolved optical coherence tomography for its applicability to provide feedback to the ophthalmologist about the introduced retinal damage during laser photocoagulation ...
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    5. Single-pulse CARS based multimodal nonlinear optical microscope for bioimaging

      Single-pulse CARS based multimodal nonlinear optical microscope for bioimaging
      Noninvasive label-free imaging of biological systems raises demand not only for high-speed three-dimensional prescreening of morphology over a wide-field of view but also it seeks to extract the microscopic functional and molecular details within. Capitalizing on the unique advantages brought out by different nonlinear optical effects, a multimodal nonlinear optical microscope can be a powerful tool for bioimaging. Bringing together the intensity-dependent contrast mechanismsviasecond harmonic generation, third harmonic generation and ...
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    6. Fiber-optically integrated cost-effective spectrometer for optical coherence tomography

      Fiber-optically integrated cost-effective spectrometer for optical coherence tomography
      A tilted fiber Bragg grating (TFBG) was integrated as the dispersive element in a high performance biomedical imaging system. The spectrum emitted by the 23 mm long active region of the fiber is projected through custom designed optics consisting of a cylindrical lens for vertical beam collimation and successively by an achromatic doublet onto a linear detector array. High resolution tomograms of biomedical samples were successfully acquired by the frequency ...
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    7. Cost-effective optical coherence tomography spectrometer based on a tilted fiber Bragg grating

      Cost-effective optical coherence tomography spectrometer based on a tilted fiber Bragg grating
      A compact, fiber-based spectrometer for biomedical application utilizing a tilted fiber Bragg grating (TFBG) as integrated dispersive element is demonstrated. Based on a 45 UV-written PS750 TFBG a refractive spectrometer with 2.06 radiant/m dispersion and a numerical aperture of 0.1 was set up and tested as integrated detector for an optical coherence tomography (OCT) system. Featuring a 23 mm long active region at the fiber the spectrum ...
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    8. Feature Of The Week 12/1/13: Simultaneous Dual Wavelength Eye-Tracked Ultrahigh Resolution Retinal and Choroidal OCT

      Feature Of The Week 12/1/13: Simultaneous Dual Wavelength Eye-Tracked Ultrahigh Resolution Retinal and Choroidal OCT
      An eye-tracked high resolution OCT device is presented for clinical multimodal imaging of the retina and the deep choroid, based on the platform of a commercial Heidelberg-Engineering SPECTRALIS OCT device. The system is aimed to drive the development of novel therapeutic approaches for better eye care. The dual spectrometer based frequency domain OCT with built-in confocal scanning laser ophthalmoscope (SLO) operating at 735 nm, corrects for eye-motion in real time ...
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    9. Simultaneous dual wavelength eye-tracked ultrahigh resolution retinal and choroidal optical coherence tomography

      Simultaneous dual wavelength eye-tracked ultrahigh resolution retinal and choroidal optical coherence tomography
      We demonstrate an optical coherence tomography device that simultaneously combines different novel ultrabroad bandwidth light sources centered in the 800 and 1060 nm regions, operating at 66 kHz depth scan rate, and a confocal laser scanning ophthalmoscope-based eye tracker to permit motion-artifact-free, ultrahigh resolution and high contrast retinal and choroidal imaging. The two wavelengths of the device provide the complementary information needed for diagnosis of subtle retinal changes, while also ...
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    10. Miniature spectrometer and beam splitter for an optical coherence tomography on a silicon chip

      Miniature spectrometer and beam splitter for an optical coherence tomography on a silicon chip
      Optical coherence tomography (OCT) has enabled clinical applications that revolutionized in vivo medical diagnostics. Nevertheless, its current limitations owing to cost, size, complexity, and the need for accurate alignment must be overcome by radically novel approaches. Exploiting integrated optics, we assemble the central components of a spectral-domain OCT system on a silicon chip. The spectrometer comprises an arrayed-waveguide grating with 136-nm free spectral range and 0.21-nm wavelength resolution. The ...
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    11. Advanced integrated spectrometer designs for miniaturized optical coherence tomography systems

      Advanced integrated spectrometer designs for miniaturized optical coherence tomography systems
      Optical coherence tomography (OCT) has enabled clinical applications that revolutionized in vivo medical diagnostics. Nevertheless, its current limitations owing to cost, size, complexity, and the need for accurate alignment must be overcome by radically novel approaches. Exploiting integrated optics, the central components of a spectral-domain OCT (SD-OCT) system can be integrated on a chip. Arrayed-waveguide grating (AWG) spectrometers with their high spectral resolution and compactness are excellent candidates for on-chip ...
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    12. Choroidal Thinning in Diabetes Type 1 Detected by 3-Dimensional 1060 nm Optical Coherence Tomography

      Choroidal Thinning in Diabetes Type 1 Detected by 3-Dimensional 1060 nm Optical Coherence Tomography
      Purpose. To map choroidal (ChT) and retinal thickness (RT) in patients with diabetes type 1 with and without maculopathy and retinopathy in order to compare them with healthy subjects using high speed 3-dimensional (3D) 1060 nm optical coherence tomography (OCT). Methods. Thirty-three eyes from 33 diabetes type 1 subjects (23–57 years, 15 male) divided into groups of without pathology (NDR) and with pathology (DR; including microaneurysms, exudates, clinically significant ...
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  2. About Boris Považay

    Boris Považay

    Boris Povazay received his Ph.D. degree in Electrical Engineering from the Vienna University of Technology in 2006. From 2006 to 2009 he was lecturer at the School of Optometry and Vision Sciences, Cardiff University. In 2010 he joined the Center for Medical Physics and Biomedical Engineering, Medical University of Vienna as assistant professor. Since 2012 he works at the OptoLab at the Institute for Human Centered Engineering, Bern University of Applied Sciences and in the semiconductor industry. His current research interests are focused on development of novel imaging modalities such as OCT and other optical processes and applications in lithography and biomedicine.