1. Biwei Yin

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    1. Mentioned In 20 Articles

    2. Stromal Nerve Imaging and Tracking Using Micro-Optical Coherence Tomography

      Explore TVST Journal Ophthalmology
      Stromal Nerve Imaging and Tracking Using Micro-Optical Coherence Tomography
      urpose : To image, track and map the nerve fiber distribution in excised rabbit corneas over the entire stromal thickness using micro-optical coherence tomography (OCT) to develop a screening tool for early peripheral neuropathy. Methods : Excised rabbit corneas were consecutively imaged by a custom-designed OCT prototype and a commercial laser scanning fluorescence confocal microscope. The OCT images with a field of view of approximately 1 1 mm were recorded with axial ...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    3. Apparatus and methods for mirror tunnel imaging device and for providing pseudobessel beams in a miniaturized optical system for imaging

      Explore uspto.gov Ophthalmology , Patents
      Apparatus and methods for mirror tunnel imaging device and for providing pseudobessel beams in a miniaturized optical system for imaging
      Exemplary apparatus and method are provided for illuminating a sample. With such exemplary apparatus and/or method, it is possible to, using at least one source arrangement, provide at least one first electro-magnetic radiation. Using an optical system of an optics arrangement, it is possible to receive the first electro-magnetic radiation(s), and modifying the at least one first electro-magnetic radiation to be at least one second electro-magnetic radiation so ...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    7. Cellular-resolution, extended depth of focus optical coherence tomography catheter toward in vivo cardiovascular imaging

      Explore SPIE Digital Library Cardiology
      Cellular-resolution, extended depth of focus optical coherence tomography catheter toward in vivo cardiovascular imaging
      Optical coherence tomography (OCT) has been a useful clinical tool for diagnosing coronary artery disease through a flexible catheter, but its full promise relies on resolving cellular and sub-cellular structures in vivo. Previously, visualizing cellular structures through an imaging catheter is not possible due to limited depth of focus (DOF) of a tightly focused Gaussian beam: typically, a Gaussian beam with 2-3 m resolution has a DOF within 100 m ...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    8. Extended depth of focus for coherence-based cellular imaging

      Explore OSA | OSA Publishing
      Extended depth of focus for coherence-based cellular imaging
      Improving lateral resolution for cross-sectional optical coherence tomography (OCT) imaging is difficult due to the rapid divergence of light once it is focused to a small spot. To overcome this obstacle, we introduce a fiber optics system that generates a coaxially focused multimode (CAFM) beam for depth of focus (DOF) extension. We fabricated a CAFM beam OCT probe and show that the DOF is more than fivefold that of a ...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    9. Flexible, high-resolution micro-optical coherence tomography endobronchial probe toward in vivo imaging of cilia

      Explore OSA | OSA Publishing Pulmonology , Probes
      Flexible, high-resolution micro-optical coherence tomography endobronchial probe toward in vivo imaging of cilia
      We report the design and fabrication of a flexible, longitudinally scanning high-resolution micro-optical coherence tomography (OCT) endobronchial probe, optimized for micro-anatomical imaging in airways. The 2.4 mm diameter and flexibility of the probe allows it to be inserted into the instrument channel of a standard bronchoscope, enabling real-time video guidance of probe placement. To generate a depth-of-focus enhancing annular beam, we utilized a new fabrication method, whereby a hollow ...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital University of Alabama

    10. Feature of the Week 04/24/2016: μOCT Imaging Using Depth of Focus Extension by Self-Imaging Wavefront Division in a Common-Path Fiber Optic Probe

      Explore Optical Coherence Tomography News
      Feature of the Week 04/24/2016: μOCT Imaging Using Depth of Focus Extension by Self-Imaging Wavefront Division in a Common-Path Fiber Optic Probe
      ...aging in catheter/endoscope-based medical imaging devices. For more information see recent Article . Courtesy Biwei Yin from Massachusetts General Hospital . Optical coherence tomography (OCT) is an attractive medical mo...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    11. μOCT imaging using depth of focus extension by self-imaging wavefront division in a common-path fiber optic probe

      Explore OSA | OSA Publishing
      μOCT imaging using depth of focus extension by self-imaging wavefront division in a common-path fiber optic probe
      Optical coherence tomography (OCT) is an attractive medical modality due to its ability to acquire high-resolution, cross-sectional images inside the body using flexible, small-diameter, scanning fiber optic probes. Conventional, cross-sectional OCT imaging technologies have approximately 10-m axial resolution and 30-m lateral resolution, specifications that enable the visualization of microscopic architectural morphology. While this resolution is useful for many clinical applications, it is insufficient for resolving individual cells that characterize many ...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    12. Fourier optics analysis of phase-mask-based path-length-multiplexed optical coherence tomography

      Explore OSA | OSA Publishing
      Fourier optics analysis of phase-mask-based path-length-multiplexed optical coherence tomography
      Imaging below fingertip surface might be a useful alternative to the traditional fingerprint sensing since the internal finger features are more reliable than the external ones. One of the most promising subsurface imaging technique is optical coherence tomography (OCT), which, however, has to acquire 3-D data even when a single en face image is required. This makes OCT inherently slow for en face imaging and produce unnecessary large data sets ...
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      Mentions: Thomas E. Milner Marc D. Feldman University of Texas at Austin

    13. Detection of plaque structure and composition using OCT combined with two-photon luminescence (TPL) imaging

      Explore Wiley Online Library Cardiology
      Detection of plaque structure and composition using OCT combined with two-photon luminescence (TPL) imaging
      Background and Objectives Atherosclerosis and plaque rupture leads to myocardial infarction and stroke. A novel hybrid optical coherence tomography (OCT) and two-photon luminescence (TPL) fiber-based imaging system was developed to characterize tissue constituents in the context of plaque morphology. Study Design/Materials and Methods Ex vivo coronary arteries (34 regions of interest) from three human hearts with atherosclerotic plaques were examined by OCTTPL imaging. Histological sections (4m in thickness) were ...
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      Mentions: Thomas E. Milner Marc D. Feldman University of Texas at Austin

    15. Degradation in the degree of polarization in human retinal nerve fiber layer

      Explore SPIE | Journal Ophthalmology
      Degradation in the degree of polarization in human retinal nerve fiber layer
      Using a fiber-based swept-source (SS) polarization-sensitive optical coherence tomography (PS-OCT) system, we investigate the degree of polarization (DOP) of light backscattered from the retinal nerve fiber layer (RNFL) in normal human subjects. Algorithms for processing data were developed to analyze the deviation in phase retardation and intensity of backscattered light in directions parallel and perpendicular to the nerve fiber axis (fast and slow axes of RNFL). Considering superior, inferior, and ...
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      Mentions: Thomas E. Milner University of Texas at Austin Biwei Yin
    17. 1-15 of 20 1 2 »
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  4. About Biwei Yin

    Biwei Yin

    Biwei Yin, is currently a postdoctoral research fellow in Dr. Tearney’s lab in Wellman Center for Photomedicine, MGH, and Harvard Medical School. He obtained his PhD degree in Electrical and Computer Engineering department in the University of Texas at Austin under Dr. Thomas Milner’s supervision. His research interest lies in optical imaging system development.

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      10 articles also mentioned Thomas E. Milner
    2. μOCT imaging using depth of focus extension by self-imaging wavefront division in a common-path fiber optic probe
      10 articles also mentioned Massachusetts General Hospital
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