1. Bioptigen

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    1. Mentioned In 167 Articles

    2. 3D graph-based automated segmentation of corneal layers in anterior-segment optical coherence tomography images of mice

      3D graph-based automated segmentation of corneal layers in anterior-segment optical coherence tomography images of mice

      Anterior segment optical coherence tomography (AS-OCT) is a non-invasive imaging modality that allows for the quantitative assessment of corneal thicknesses. Automated approaches for these measurements are not readily available and therefore measurements are often obtained manually. While graph-based approaches that enable the optimal simultaneous segmentation of multiple 3D surfaces have been proposed and applied to 3D optical coherence tomography volumes of the back of the eye, such approaches have not been applied for the segmentation of the corneal surfaces. In this work we propose adapting this graph-based method for the automated 3D segmentation of three corneal surfaces in AS-OCT images ...

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    3. Optical coherence tomography (OCT) imaging systems for use in ophthalmic applications

      Optical coherence tomography (OCT) imaging systems for use in ophthalmic applications

      Optical coherence tomography (OCT) imaging systems for imaging an eye are provided including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path, the reference arm path having an associated reference arm path length. A sample having an associated sample arm path coupled to the source arm and reference arm paths is provided. A reference arm path length adjustment module is coupled to the reference arm. The reference arm path length adjustment module is configured to automatically adjust the reference arm path length such that the reference ...

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    4. Systems for processing images generated using fourier domain optical coherence tomography (FDOCT)

      Systems for processing images generated using fourier domain optical coherence tomography (FDOCT)

      Methods, systems and computer program products for managing frequency domain optical coherence tomography (FDOCT) image resolution. A spectrum used to acquire an image of a subject is calibrated and default dispersion correction parameters are set. Default dispersion management parameters associated with a region of the image of the subject are also set. The image of the subject is acquires after setting the default dispersion correction parameters and the default dispersion management parameters. A quality of the acquired image is compared to a quality metric for the acquired image. The dispersion correction parameters are adjusted if the quality of the acquired ...

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    5. Bioptigen Introduces Dynamic 3D Tissue Flattening Software for Envisu SD-OCT Systems (See Video)

      Bioptigen Introduces Dynamic 3D Tissue Flattening Software for Envisu SD-OCT Systems  (See Video)
      ...shed citing data acquired with Bioptigen technologies. Learn more about Bioptigen and its technologies at www.bioptigen.com. Software is first to enable continuous optical sectioning along true anatomical contours Biop...
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    6. Disruption of Sarcoendoplasmic Reticulum Calcium ATPase Function in Drosophila Leads to Cardiac Dysfunction

      Disruption of Sarcoendoplasmic Reticulum Calcium ATPase Function in Drosophila Leads to Cardiac Dysfunction

      Abnormal sarcoendoplasmic reticulum Calcium ATPase (SERCA) function has been associated with poor cardiac function in humans. While modifiers of SERCA function have been identified and studied using animal models, further investigation has been limited by the absence of a model system that is amenable to large-scale genetic screens. Drosophila melanogaster is an ideal model system for the investigation of SERCA function due to the significant homology to human SERCA and the availability of versatile genetic screening tools. To further the use of Drosophila as a model for examining the role of SERCA in cardiac function, we examined cardiac function in ...

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  2. About Bioptigen

    Bioptigen

    Bioptigen.  Ophthalmology and General Research Systems.  Bioptigen has pioneered a new class of in vivo optical imaging systems for biomedical applications. These systems enable real-time non-invasive imaging of internal tissue microstructure, advancing critical applications in drug development, genetics research, tissue engineering, and medical vision.  Bioptigen is a spin-out of the Duke University Biomedical Engineering Department. Bioptigen was incorporated in North Carolina in August, 2004, to commercialize technologies originating in the laboratories of Professor Joseph Izatt. Bioptigen technology is based on the science of Optical Coherence Tomography (OCT), an imaging system similar in function to ultrasound, but using low-power light rather than sound waves. OCT offers resolution 100-times finer than standard ultrasound, suitable for analyzing tissue microstructure with features smaller than 10 micrometer.

  3. Quotes about Bioptigen

    1. Bioptigen allows you to sum up multiple images of a particular cut.
      In New Technology: Bioptigen SDOCT Boosts Flexibility
    2. Bioptigen is very pleased to extend its relationship with Case through this new technology agreement.  The intellectual property licensed by Case is fundamental to our ability to provide the highest performance FDOCT imaging system today and to develop new clinical tools that will dramatically extend the clinical value of FDOCT into the future.
      Eric L. Buckland in Case Western Reserve University, University Hospitals Case Medical Center and Bioptigen Establish Exclusive Licensing Agreement
    3. We look forward to working with Bioptigen to incorporate the Case technology and expand their product portfolio to address medical disciplines beyond ocular imaging.
      In Case Western Reserve University, University Hospitals Case Medical Center and Bioptigen Establish Exclusive Licensing Agreement