1. About Bioptigen

    Bioptigen

    Bioptigen.  Ophthalmology and General Research Systems.  Bioptigen has pioneered a new class of in vivo optical imaging systems for biomedical applications. These systems enable real-time non-invasive imaging of internal tissue microstructure, advancing critical applications in drug development, genetics research, tissue engineering, and medical vision.  Bioptigen is a spin-out of the Duke University Biomedical Engineering Department. Bioptigen was incorporated in North Carolina in August, 2004, to commercialize technologies originating in the laboratories of Professor Joseph Izatt. Bioptigen technology is based on the science of Optical Coherence Tomography (OCT), an imaging system similar in function to ultrasound, but using low-power light rather than sound waves. OCT offers resolution 100-times finer than standard ultrasound, suitable for analyzing tissue microstructure with features smaller than 10 micrometer.

  2. Quotes about Bioptigen

    1. Bioptigen allows you to sum up multiple images of a particular cut.
      In New Technology: Bioptigen SDOCT Boosts Flexibility
    2. Bioptigen is very pleased to extend its relationship with Case through this new technology agreement.  The intellectual property licensed by Case is fundamental to our ability to provide the highest performance FDOCT imaging system today and to develop new clinical tools that will dramatically extend the clinical value of FDOCT into the future.
      Eric L. Buckland in Case Western Reserve University, University Hospitals Case Medical Center and Bioptigen Establish Exclusive Licensing Agreement
    3. We look forward to working with Bioptigen to incorporate the Case technology and expand their product portfolio to address medical disciplines beyond ocular imaging.
      In Case Western Reserve University, University Hospitals Case Medical Center and Bioptigen Establish Exclusive Licensing Agreement
  1. Bioptigen

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    1. Mentioned In 102 Articles

    2. Bioptigen Receives FDA Clearance to Market Envisu Imaging Systems in the USA

      Explore Optical Coherence Tomography News (5 hours, 44 min ago)

      Bioptigen Receives FDA Clearance to Market Envisu Imaging Systems in the USA Bioptigen Press Release - Devices become first OCT systems cleared for hand-held ophthalmic imaging of childr... (Read Full Article)

      Mentions:   National Institutes of Health   Eric L. Buckland   Bioptigen

    3. Methods, systems and computer program products for mixed-density optical coherence tomography (OCT) imaging

      Explore uspto.gov (May 15 2012)

      Methods, systems and computer program products for mixed-density optical coherence tomography (OCT) imaging Methods, systems and computer program products are provided for acquiring an image set using optical coherence tomography (OCT). A first portion of a defined volume is scanned at a low-density sampling rate to obtain a plurality of low-density frames. A second portion of the defined volume is scanned at a high-density sampling rate, higher than the low-density sampling rate, to obtain at least one high-density frame. The low-density frames and ... (Read Full Article)

      Mentions:   Eric L. Buckland   Cynthia A. Toth   Bioptigen

    4. Long-Term Characterization of Retinal Degeneration in rd1 and rd10 Mice Using Spectral Domain Optical Coherence Tomography

      Explore iovs.org (May 4 2012)

      Long-Term Characterization of Retinal Degeneration in rd1 and rd10 Mice Using Spectral Domain Optical Coherence Tomography ...ectral Domain Optical Coherence Tomography (SD-OCT). Methods. SD-OCT images were obtained using the Bioptigen Spectral Domain Ophthalmic Imaging System (SDOIS). Wild-type C57BL/6J, rd1 and rd10 mice ranging in... (Read Full Article)

      Mentions:   Bioptigen   Oregon Health & Science University

    5. OCT Moves from Clinic to OR to . . . Home?

      Explore Photonics.com (May 2 2012)

      OCT Moves from Clinic to OR to . . . Home? ...patients who can’t remain in an upright position comfortably, or even for fidgety younger patients. Bioptigen Inc. of Research Triangle Park, N.C., started the handheld field just five years ago, with a device... (Read Full Article)

      Mentions:   Duke University   Alexander C. Walsh   Bioptigen

    6. Real Time Intraoperative Spectral Domain Optical Coherence Tomography for Vitreoretinal Surgery

      Explore ClinicalTrials.gov (Apr 26 2012)

      Real Time Intraoperative Spectral Domain Optical Coherence Tomography for Vitreoretinal Surgery ...6, 2012. Last Updated on April 27, 2012 History of Changes Sponsor: Duke University Collaborator: Bioptigen, Inc. Information provided by (Responsible Party): Duke University ClinicalTrials.gov Identifier: N... (Read Full Article)

      Mentions:   Duke University   Cynthia A. Toth   Bioptigen

    7. Spectral-Domain Optical Coherence Tomography as a Non-Invasive Method to Assess Damaged and Regenerating Adult Zebrafish Retinas

      Explore iovs.org (Apr 14 2012)

      Spectral-Domain Optical Coherence Tomography as a Non-Invasive Method to Assess Damaged and Regenerating Adult Zebrafish Retinas PURPOSE. These experiments assessed the ability of spectral domain optical coherence tomography (SD-OCT) to accurately represent the structural organization of the adult zebrafish retina and reveal the dynamic morphological changes during either light-induced damage and regeneration of photoreceptors or ouabain-induced inner retinal damage. METHODS. Retinas of control dark-adapted adult albino zebrafish were compared to retinas subjected to 24 hours of constant intense light and recovered for up to 8 weeks ... (Read Full Article)

      Mentions:   Bioptigen

    8. Bioptigen Receives $1.2M NIH Grant for Pediatric Spectral Domain Optical Coherence Tomography

      Explore Optical Coherence Tomography News (Mar 23 2012)

      Bioptigen Receives $1.2M NIH Grant for Pediatric Spectral Domain Optical Coherence Tomography Bioptigen received a $1,257,593 Calendar Year 2012 NIH Grant for Pediatric Spectral Domain Optical Coherence ... (Read Full Article)

      Mentions:   Bioptigen   Bradley A. Bower

    9. Image inversion spectral-domain optical coherence tomography optimizes choroidal thickness and detail through improved contrast

      Explore iovs.org (Mar 13 2012)

      Image inversion spectral-domain optical coherence tomography optimizes choroidal thickness and detail through improved contrast ...200 µm. Results: Mean choroidal thickness was greater in inverted versus upright images captured by Bioptigen (p≤0.003) and Spectralis (p≤0.015). Choroidal thickness varied significantly between the three mach... (Read Full Article)

      Mentions:   Heidelberg Engineering   Duke University   Cynthia A. Toth

    10. Bioptigen Receives Clearance to Market Envisu SDOIS in Canada

      Explore Optical Coherence Tomography News (Feb 27 2012)

      Bioptigen Receives Clearance to Market Envisu SDOIS in Canada ...in marketing its hand-held Envisu SDOIS C2200 and C2300 ophthalmic imaging systems for patient use. Bioptigen’s Envisu C series SDOIS imaging systems use low-power, near-infrared light to generate real-time, h... (Read Full Article)

      Mentions:   National Institutes of Health   Eric L. Buckland   Bioptigen

    11. Morphometric measurement of Schlemm’s canal in normal human eye using anterior segment swept source optical coherence tomography

      Explore Linking to Scitation Content (Feb 23 2012)

      Morphometric measurement of Schlemm’s canal in normal human eye using anterior segment swept source optical coherence tomography We have used anterior segment swept source optical coherence tomography to measure Schlemm’s canal (SC) morphometric values in the living human eye. Fifty healthy volunteers with 100 normal eyes were measured in the nasal and temporal side. Comparison with the published SC morphometric values of histologic sections proves the reliability of our results. The statistical results show that there are no significant differences between nasal and temporal SC with ... (Read Full Article)

      Mentions:   Fudan University   Bioptigen   Zhejiang University

    12. Optical coherence imaging systems having a mechanism for shifting focus and scanning modality

      Explore uspto.gov (Feb 21 2012)

      Optical coherence imaging systems having a mechanism for shifting focus and scanning modality Some embodiments of the present invention provide adapters for use in posterior imaging systems. The adapters include lens set configured to adapt the posterior imaging system to operate as an anterior imaging system. Related optical coherence tomography systems and anterior imaging systems are also provided herein (Read Full Article)

      Mentions:   Joseph A. Izatt   Eric L. Buckland   Bioptigen

    13. This Is What Job Creation Really Looks Like

      Explore theatlantic.com (Feb 17 2012)

      This Is What Job Creation Really Looks Like ...o create middle-class jobs as well, but in a completely different way. Buckland is the president of Bioptigen, an 18-employee high-tech startup that manufactures handheld retinal scanners used by eye doctors a... (Read Full Article)

      Mentions:   Duke University   Eric L. Buckland   Bioptigen

    14. Study of the Global Optical Coherence Tomography Market

      Explore PR Newswire (Feb 15 2012)

      Study of the Global Optical Coherence Tomography Market ...For any research requirements please write to smartresearchinsights@gmail.com Companies Mentioned 1 Bioptigen, Inc.2 Carl Zeiss Meditec 3 Imalux Corporation 4 OPKO Health, Inc5 Heidelberg Engineering, Inc. 1.1... (Read Full Article)

      Mentions:   Imalux   Bioptigen   Carl Zeiss Meditec

    15. A miniature forward-imaging optical coherence tomography (OCT) probe

      Explore Linking to Scitation Content (Feb 9 2012)

      A miniature forward-imaging optical coherence tomography (OCT) probe ...ed and developed to use with an 850 nm spectral-domain optical coherence tomography (SDOCT) system (Bioptigen, Inc. Durham, NC). Imaging parameters were determined. Ocular tissues were examined with the miniat... (Read Full Article)

      Mentions:   Vanderbilt University   Bioptigen

    16. Compact Multimodality Optical Coherence Tomography Imaging Systems And Related Methods And Computer Program Products

      Explore wipo.int (Feb 9 2012)

      Compact Multimodality Optical Coherence Tomography Imaging Systems And Related Methods And Computer Program Products Systems for imaging a sample are provided. The system includes an optical coherence tomography (OCT) imaging portion having an associated OCT path defined by one set of optical elements between an OCT signal delivery optical fiber and the sample; an image capture portion having an associated image capture path defined by a second set of optical elements between an image capture device and the sample, different from the OCT path ... (Read Full Article)

      Mentions:   Eric L. Buckland   Bioptigen   Bradley A. Bower

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