1. Bioptigen

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    1. Mentioned In 173 Articles

    2. Compact multimodality optical coherence tomography imaging systems

      Compact multimodality optical coherence tomography imaging systems

      Systems for imaging a sample are provided. The system includes an optical coherence tomography (OCT) imaging portion having an associated OCT path defined by one set of optical elements between an OCT signal delivery optical fiber and the sample; an image capture portion having an associated image capture path defined by a second set of optical elements between an image capture device and the sample, different from the OCT path; and an illuminator portion having an associated illumination path defined by a third set of optical elements between an illumination source and the sample. The OCT path, the image capture ...

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    3. Optical imaging systems having input beam shape control and path length control

      Optical imaging systems having input beam shape control and path length control

      Scanning optical beam imaging systems for imaging a surface with convex curvature are provided. The systems include a sphero-telecentric objective, wherein a scanning radius of curvature of the sphero-telecentric objective is greater than an apical radius of curvature of the surface and less than or equal to four times an apical radius of curvature of the surface.

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    4. Cleveland Clinic / CWRU NIH Grant for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery

      Cleveland Clinic / CWRU NIH Grant for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery
      ... collaborators in instrument design (Peregrine Surgical), software development (ImageIQ), and OCT technology (Bioptigen). These partnerships also greatly strengthen the foundation of the proposal and the likelihood of bo...
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    5. Linearized variable-dispersion spectrometers and related assemblies

      Linearized variable-dispersion spectrometers and related assemblies

      Wavenumber linear spectrometers are provided including an input configured to receive electromagnetic radiation from an external source; collimating optics configured to collimate the received electromagnetic radiation; a dispersive assembly including first and second diffractive gratings, wherein the first diffraction grating is configured in a first dispersive stage to receive the collimated electromagnetic radiation and wherein the dispersive assembly includes at least two dispersive stages configured to disperse the collimated input; and an imaging lens assembly configured to image the electromagnetic radiation dispersed by the at least two dispersive stages onto a linear detection array such that the variation in frequency ...

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    6. Optical coherence tomography (OCT) imaging systems having adaptable lens systems and related methods and computer program products

      Optical coherence tomography (OCT) imaging systems having adaptable lens systems and related methods and computer program products

      OCT imaging systems are provided for imaging a spherical-type eye including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path. The reference arm path has an associated reference arm path length. A sample is also provided having an associated sample arm path coupled to the source arm and reference arm paths. A lens having a focal power optimized for a diameter of the spherical-type eye is provided along with a reference arm path length adjustment module coupled to the reference arm. The reference arm path length ...

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    7. Methods, systems and computer program products for diagnosing conditions using unique codes generated from a multidimensional image of a sample

      Methods, systems and computer program products for diagnosing conditions using unique codes generated from a multidimensional image of a sample

      Methods of providing a diagnosis using a digital code associated with an image are provided including collecting a multidimensional image, the multidimensional image having at least two dimensions; extracting a two dimensional subset of the multidimensional image; reducing the multidimensional image to a first code that is unique to the multidimensional image based on the extracted two dimensional image; comparing the first unique code associated with the subject to a library of reference codes, each of the reference codes in the library of reference codes being indicative of a class of objects; determining if the subject associated with the first ...

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    8. Surgical microscopes using optical coherence tomography and related methods

      Surgical microscopes using optical coherence tomography and related methods

      Some embodiments of the present inventive concept provide optical coherence tomography (OCT) systems for integration with a microscope. The OCT system includes a sample arm coupled to the imaging path of a microscope. The sample arm includes an input beam zoom assembly including at least two movable lenses configured to provide shape control for an OCT signal beam; a scan assembly including at least one scanning mirror and configured for telecentric scanning of the OCT signal beam; and a beam expander configured to set the OCT signal beam diameter incident on the microscope objective. The shape control includes separable controls ...

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    9. Zebrafish as a Model to Study Emmetropization, Refractive Error, and Retinal Substructure using Spectral Domain-Optical Coherence Tomography

      Zebrafish as a Model to Study Emmetropization, Refractive Error, and Retinal Substructure using Spectral Domain-Optical Coherence Tomography
      ...d lens diameter were measured in wild-type and bugeye/lrp2 mutant zebrafish throughout their lifespan using a Bioptigen SD-OCT system. Cone photoreceptor mosaics were visualized using en face summed volume projection (SV...
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    10. Methods, systems and computer program products for collapsing volume data to lower dimensional representations thereof using histogram projection

      Methods, systems and computer program products for collapsing volume data to lower dimensional representations thereof using histogram projection

      Methods of collapsing volume data to a lower dimensional representation of the volume data are provided. The methods include collapsing volume data to a lower dimensional representation of the volume data using histogram projection. Related systems and computer program products are also provided.

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  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
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  2. About Bioptigen

    Bioptigen

    Bioptigen.  Ophthalmology and General Research Systems.  Bioptigen has pioneered a new class of in vivo optical imaging systems for biomedical applications. These systems enable real-time non-invasive imaging of internal tissue microstructure, advancing critical applications in drug development, genetics research, tissue engineering, and medical vision.  Bioptigen is a spin-out of the Duke University Biomedical Engineering Department. Bioptigen was incorporated in North Carolina in August, 2004, to commercialize technologies originating in the laboratories of Professor Joseph Izatt. Bioptigen technology is based on the science of Optical Coherence Tomography (OCT), an imaging system similar in function to ultrasound, but using low-power light rather than sound waves. OCT offers resolution 100-times finer than standard ultrasound, suitable for analyzing tissue microstructure with features smaller than 10 micrometer.

  3. Quotes about Bioptigen

    1. Bioptigen allows you to sum up multiple images of a particular cut.
      In New Technology: Bioptigen SDOCT Boosts Flexibility
    2. Bioptigen is very pleased to extend its relationship with Case through this new technology agreement.  The intellectual property licensed by Case is fundamental to our ability to provide the highest performance FDOCT imaging system today and to develop new clinical tools that will dramatically extend the clinical value of FDOCT into the future.
      Eric L. Buckland in Case Western Reserve University, University Hospitals Case Medical Center and Bioptigen Establish Exclusive Licensing Agreement
    3. We look forward to working with Bioptigen to incorporate the Case technology and expand their product portfolio to address medical disciplines beyond ocular imaging.
      In Case Western Reserve University, University Hospitals Case Medical Center and Bioptigen Establish Exclusive Licensing Agreement