1. University of Illinois at Urbana-Champaign

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    1. Mentioned In 240 Articles

    2. Coherent optical imaging and guided interventions in breast cancer: translating technology into clinical applications

      ...in breast cancer: translating technology into clinical applications Univ. of Illinois at Urbana-Champaign and Mills Breast Cancer Institute (published online Apr. 17, 2008) Breast cancer continues to be one of the most w...
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    3. Stabilization of continuum generation from normally dispersive nonlinear optical fibers for a tunable broad bandwidth source for optical coherence tomography

      Haohua Tu, Daniel L. Marks, Yee Lin Koh, and Stephen A. Boppart Continuum generation from normally dispersive ultrahigh-numerical-aperture fibers deteriorates in relatively short times, limiting its application as a practical optical source for high-resolution optical coherence tomography. We find that reversible light-induced structural modification of fiber optic materials, rather than permanent optical damage, is responsible for this deterioration. By examining how the optical properties of corresponding light-induced waveguides depend on ...
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    4. Interferometric synthetic aperture microscopy: tissue structure inferred by computed imaging techniques

      Interferometric synthetic aperture microscopy: tissue structure inferred by computed imaging techniques
      Daniel L. Marks, Tyler S. Ralston, Brynmor J. Davis et al. Interferometric Synthetic Aperture Microscopy (ISAM) is an optical microscopy computed-imaging technique for measuring the optical properties of three-dimensional structures and biological tissues. In this work, the principle of ISAM is reviewed, and its application to imaging tissue properties in v ... [Proc. SPIE Int. Soc. Opt. Eng. 6864, 686407 (2008)] published Fri Feb 15, 2008.
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    5. Plasmon-resonant gold nanorods provide spectroscopic OCT contrast in excised human breast tumors

      Amy L. Oldenburg, Matthew N. Hansen, Alexander Wei et al. Plasmon-resonant gold nanorods have been demonstrated recently as contrast agents for optical coherence tomography (OCT). To evaluate their ability to produce contrast in a structurally heterogeneous environment, nanorods were injected at discrete locations into an excised sample of human breast inv ... [Proc. SPIE Int. Soc. Opt. Eng. 6867, 68670E (2008)] published Wed Feb 13, 2008.
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    6. Real-time interferometric synthetic aperture microscopy

      Tyler S. Ralston, Daniel L. Marks, P. S. Carney, Stephen A. Boppart. An interferometric synthetic aperture microscopy (ISAM) system design with real-time 2D cross-sectional processing is described in detail. The system can acquire, process, and display the ISAM reconstructed images at frame rates of 2.25 frames per second for 512 X 1024 pixel images. This system ... [Opt. Express 16, 2555-2569 (2008)]
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    7. Spectroscopic Optical Coherence Tomography and Microscopy

      Imaging biological tissues using optical coherence tomography is enhanced with spectroscopic analysis, providing new metrics for functional imaging. Recent advances in spectroscopic optical coherence tomography (SOCT) include techniques for the discrimination of endogenous tissue types and for the detection of exogenous contrast agents. In this paper, we review these techniques and their associated signal processing algorithms, while highlighting their potential for biomedical applications. We unify the theoretical framework for time- ...
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    8. Optical contrast agents for optically modifying incident radiation

      A method of enhancing the contrast of an image of a sample, comprises forming an image of a mixture, by exposing the mixture to electromagnetic radiation. The mixture comprises the sample and microparticles. The enhancement is particularly suitable for optical coherence tomography.
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    9. Interferometric synthetic aperture microscopy

      Interferometric synthetic aperture microscopy
      State-of-the-art methods in high-resolution three-dimensional optical microscopy require that the focus be scanned through the entire region of interest. However, an analysis of the physics of the light–sample interaction reveals that the Fourier-space coverage is independent of depth. Here we show that, by solving the inverse scattering problem for interference microscopy, computed reconstruction yields volumes with a resolution in all planes that is equivalent to the resolution achieved only ...
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  2. About University of Illinois at Urbana-Champaign

    University of Illinois at Urbana-Champaign

    The University of Illinois at Urbana-Champaign.  Illinois is a world leader in research, teaching, and public engagement, distinguished by the breadth of its programs, broad academic excellence, and internationally renowned faculty.  Biophotonics Imaging Laboratory at the University of Illinois at Urbana-Champaign. Located in the Beckman Institute for Advanced Science and Technology at the University of Illinois at Urbana-Champaign, the Biophotonics Imaging Laboratory, directed by Professor Stephen Boppart, is dedicated to the development of optical biomedical imaging techniques. Mills Breast Cancer Institute is dedicated to the diagnosis, prevention and treatment of breast cancer through collaborative research and excellence in patient care.   Dr. Stephen Boppart, MD, PhD, Founding Director, Mills Breast Cancer Institute.