1. University of Illinois at Urbana-Champaign

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    1. Mentioned In 239 Articles

    2. Multi-functional plasmon-resonant contrast agents for optical coherence tomography

      A method of forming an image of a sample, comprising: forming an image of a mixture, by exposing the mixture to electromagnetic radiation; wherein the mixture comprises the sample and plasmon-resonant nanoparticles, and wherein the electromagnetic radiation is in the frequency range of infra-red to ultraviolet light.
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    3. Interferometric synthetic aperture microscopy

      Methods and apparatus for three-dimensional imaging of a sample. A source is provided of a beam of substantially collimated light characterized by a temporally dependent spectrum. The beam is focused in a plane characterized by a fixed displacement along the propagation axis of the beam, and scattered light from the sample is superposed with a reference beam derived from the substantially collimated source onto a focal plane detector array to ...
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    4. Biomechanical Properties of in Vivo Human Skin From Dynamic Optical Coherence Elastography

      Biomechanical Properties of in Vivo Human Skin From Dynamic Optical Coherence Elastography
      Dynamic optical coherence elastography is used to determine in vivoskin biomechanical properties based on mechanical surface wave propagation. Quantitative Youngs moduli are measured on human skin from different sites, orientations, and frequencies. Skin thickness, including measurements from different layers, are also measured simultaneously. Experimental results show significant differences among measurements from different skin sites, between directions parallel and orthogonal to Langers lines, and under different skin hydration states. Results also ...
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    5. Acoustomotive optical coherence elastography for measuring material mechanical properties

      Acoustomotive optical coherence elastography for measuring material mechanical properties
      Acoustomotive optical coherence elastography (AM-OCE), a dynamic and internal excitation optical coherence elastography technique, is reported. Acoustic radiation force was used for internal mechanical excitation, and spectral-domain optical coherence tomography was used for detection. Mechanical properties of gelatin tissue phantoms were measured by AM-OCE and verified using rheometry results. Measured mechanical properties including shear moduli and shear damping parameters of the gelatin samples double when their polymer concentration increases from ...
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    6. Detecting action-potential-correlated scattering changes in single neurons

      Detecting action-potential-correlated scattering changes in single neurons
      Optical coherence microscopy has potential as a tool for noninvasively measuring electrical activity in single neurons based on changes in their intrinsic optical properties. A central goal of neuroscience is to understand how groups of neurons interact to give rise to the myriad functions of the nervous system. This task is extremely difficult in part because of the technical challenge of recording the electrical activity of many neurons simultaneously without ...
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    7. Imaging engineered tissues using structural and functional optical coherence tomography

      As the field of tissue engineering evolves, there will be an increasingly important need to visualize and track the complex dynamic changes that occur within three-dimensional constructs. Optical coherence tomography (OCT), as an emerging imaging technology applied to biological materials, offers a number of significant advantages to visualize these changes. Structural OCT has been used to investigate the longitudinal development of engineered tissues and cell dynamics such as migration, proliferation ...
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    8. Detecting intrinsic scattering changes correlated to neuron action potentials using optical coherence imaging

      Detecting intrinsic scattering changes correlated to neuron action potentials using optical coherence imaging
      We demonstrate how optical coherence imaging techniques can detect intrinsic scattering changes that occur during action potentials in single neurons. Using optical coherence tomography (OCT), an increase in scattering intensity from neurons in the abdominal ganglion of Aplysia californica is observed following electrical stimulation of the connective nerve. In addition, optical coherence microscopy (OCM), with its superior transverse spatial resolution, is used to demonstrate a direct correlation between scattering intensity ...
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    9. Towards freehand image acquisition in optical coherence tomography

      Towards freehand image acquisition in optical coherence tomography
      A new data-capture method could provide increased flexibility for clinical imaging applications. Optical coherence tomography (OCT), a biomedical diagnostic-imaging technique, is currently transitioning from the research laboratory into clinical practice.1 Providing micrometer-scale resolution over millimeter-scale fields of view, OCT is the optical analog of ultrasound. It uses low-coherence interferometry to perform optical ranging in biological tissue. Clinical applications under investigation include optical biopsy2 and detection of tumor margins during ...
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    10. Cross-correlation-based image acquisition technique for manually-scanned optical coherence tomography

      Cross-correlation-based image acquisition technique for manually-scanned optical coherence tomography
      We present a novel image acquisition technique for Optical Coherence Tomography (OCT) that enables manual lateral scanning. The technique compensates for the variability in lateral scan velocity based on feedback obtained from correlation between consecutive A-scans. Results obtained from phantom samples and biological tissues demonstrate successful assembly of OCT images from manually-scanned datasets despite non-uniform scan velocity and abrupt stops encountered during data acquisition. This technique could enable the acquisition ...
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    11. Imaging gold nanorods in excised human breast carcinoma by spectroscopic optical coherence tomography

      Imaging gold nanorods in excised human breast carcinoma by spectroscopic optical coherence tomography
      Plasmon-resonant gold nanorods (GNRs) can serve as imaging agents for spectroscopic optical coherence tomography (SOCT). The aspect ratio of the GNRs is adjusted for maximum absorption in the far red to create a partial spectral overlap with the short-wavelength edge of the near-infrared SOCT imaging band. The spectroscopic absorption profile of the GNRs is incorporated into a depth-resolved algorithm for mapping the relative GNR density within OCT images. This technique ...
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    12. Optical coherence tomography (OCT) as a diagnostic tool for the real-time intraoperative assessment of breast cancer surgical margins.

      ..., AM Zysk1, EJ Chaney1, JG Kotynek2, UJ Oliphant2, FJ Bellafiore2, KM Rowland2, PA Johnson2 and SA Boppart1 1 University of Illinois at Urbana-Champaign, Urbana, IL 2 Carle Foundation Hospital, Carle Clinic Association, ...
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    13. 196-210 of 239 « 1 2 ... 11 12 13 14 15 16 »
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  2. About University of Illinois at Urbana-Champaign

    University of Illinois at Urbana-Champaign

    The University of Illinois at Urbana-Champaign.  Illinois is a world leader in research, teaching, and public engagement, distinguished by the breadth of its programs, broad academic excellence, and internationally renowned faculty.  Biophotonics Imaging Laboratory at the University of Illinois at Urbana-Champaign. Located in the Beckman Institute for Advanced Science and Technology at the University of Illinois at Urbana-Champaign, the Biophotonics Imaging Laboratory, directed by Professor Stephen Boppart, is dedicated to the development of optical biomedical imaging techniques. Mills Breast Cancer Institute is dedicated to the diagnosis, prevention and treatment of breast cancer through collaborative research and excellence in patient care.   Dr. Stephen Boppart, MD, PhD, Founding Director, Mills Breast Cancer Institute.