1. Bern University of Applied Sciences

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    1. Mentioned In 14 Articles

    2. Real-time optical coherence tomography observation of retinal tissue damage during laser photocoagulation therapy on ex-vivo porcine samples

      Real-time optical coherence tomography observation of retinal tissue damage during laser photocoagulation therapy on ex-vivo porcine samples
      Retinal laser photocoagulation represents a widely used treatment for retinal pathologies such as diabetic chorioretinopathy or diabetic edema. For effective treatment, an appropriate choice of the treatment energy dose is crucial to prevent excessive tissue damage caused by over-irradiation of the retina. In this manuscript we investigate simultaneous and time-resolved optical coherence tomography for its applicability to provide feedback to the ophthalmologist about the introduced retinal damage during laser photocoagulation ...
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    3. Fiber-optically integrated cost-effective spectrometer for optical coherence tomography

      Fiber-optically integrated cost-effective spectrometer for optical coherence tomography
      A tilted fiber Bragg grating (TFBG) was integrated as the dispersive element in a high performance biomedical imaging system. The spectrum emitted by the 23 mm long active region of the fiber is projected through custom designed optics consisting of a cylindrical lens for vertical beam collimation and successively by an achromatic doublet onto a linear detector array. High resolution tomograms of biomedical samples were successfully acquired by the frequency ...
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    4. Cost-effective optical coherence tomography spectrometer based on a tilted fiber Bragg grating

      Cost-effective optical coherence tomography spectrometer based on a tilted fiber Bragg grating
      A compact, fiber-based spectrometer for biomedical application utilizing a tilted fiber Bragg grating (TFBG) as integrated dispersive element is demonstrated. Based on a 45 UV-written PS750 TFBG a refractive spectrometer with 2.06 radiant/m dispersion and a numerical aperture of 0.1 was set up and tested as integrated detector for an optical coherence tomography (OCT) system. Featuring a 23 mm long active region at the fiber the spectrum ...
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    5. Feature Of The Week 12/1/13: Simultaneous Dual Wavelength Eye-Tracked Ultrahigh Resolution Retinal and Choroidal OCT

      Feature Of The Week 12/1/13: Simultaneous Dual Wavelength Eye-Tracked Ultrahigh Resolution Retinal and Choroidal OCT
      An eye-tracked high resolution OCT device is presented for clinical multimodal imaging of the retina and the deep choroid, based on the platform of a commercial Heidelberg-Engineering SPECTRALIS OCT device. The system is aimed to drive the development of novel therapeutic approaches for better eye care. The dual spectrometer based frequency domain OCT with built-in confocal scanning laser ophthalmoscope (SLO) operating at 735 nm, corrects for eye-motion in real time ...
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    6. Simultaneous dual wavelength eye-tracked ultrahigh resolution retinal and choroidal optical coherence tomography

      Simultaneous dual wavelength eye-tracked ultrahigh resolution retinal and choroidal optical coherence tomography
      We demonstrate an optical coherence tomography device that simultaneously combines different novel ultrabroad bandwidth light sources centered in the 800 and 1060 nm regions, operating at 66 kHz depth scan rate, and a confocal laser scanning ophthalmoscope-based eye tracker to permit motion-artifact-free, ultrahigh resolution and high contrast retinal and choroidal imaging. The two wavelengths of the device provide the complementary information needed for diagnosis of subtle retinal changes, while also ...
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    7. Coronary evaginations are associated with positive vessel remodelling and are nearly absent following implantation of newer-generation drug-eluting stents: an optical coherence tomography and intravascular ultrasound study

      Coronary evaginations are associated with positive vessel remodelling and are nearly absent following implantation of newer-generation drug-eluting stents: an optical coherence tomography and intravascular ultrasound study
      Objectives The purpose of this study was to assess the occurrence, predictors, and mechanisms of optical coherence tomography (OCT)-detected coronary evaginations following drug-eluting stent (DES) implantation. Background Angiographic ectasias and aneurysms in stented segments have been associated with a risk of late stent thrombosis. Using OCT, some stented segments show coronary evaginations reminiscent of ectasias. Methods Evaginations were defined as outward bulges in the luminal contour between struts. They ...
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    8. Spectroscopic optical coherence tomography for substance identification

      Spectroscopic optical coherence tomography for substance identification
      We use Spectroscopic Optical Coherence Tomography (S-OCT) to identify substances by their spectral features in multi layer non-scattering samples. Depth resolved spectra are calculated by a windowed Fourier Transform in the spatial regime at discrete layer borders. By dividing subsequent spectra in an iterative manner transfer functions of the samples layers are calculated. Estimating these spectral transfer functions with high accuracy is still challenging, since the systems transfer function introduces ...
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    9. Feature Of The Week 2/13/11: Influence and Compensation of Autocorrelation Terms in Depth-Resolved Spectroscopic FD-OCT: A Review of Work from Bern University of Applied Sciences

      Feature Of The Week 2/13/11: Influence and Compensation of Autocorrelation Terms in Depth-Resolved Spectroscopic FD-OCT: A Review of Work from Bern University of Applied Sciences
      Feature Of The Week 2/13/11: An extension to regular Fourier-Domain OCT, spectroscopic optical coherence tomography (SOCT), enables the extraction of spectral characteristics from the OCT signal of a sample or substance under investigation. For medical imaging, especially the power of SOCT to detect depth and spectrally resolved attenuation coefficients of endogenous chemicals and tissue is of interest as it could pave the way towards a variety of applications ...
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    10. Influence and compensation of autocorrelation terms in depth-resolved spectroscopic Fourier-domain optical coherence tomography

      Influence and compensation of autocorrelation terms in depth-resolved spectroscopic Fourier-domain optical coherence tomography
      We demonstrate depth-resolved spectral absorption measurements in the wavelength range from 750 to 850 nm using a broadband light source consisting of three spectrally shifted superluminescent light-emitting diode modules and a low-cost spectrometer-based Fourier-domain optical coherence tomography system. We present the theoretical model and experimental verification of interferences between autocorrelation terms and the signal carrying cross-correlation terms, strongly affecting the absorption measurements. A simple background subtraction, minimizing the artifacts caused ...
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    11. Spectroscopic measurements with dispersion encoded full range frequency domain optical coherence tomography in single- and multilayered weakly scattering phantoms

      Spectroscopic measurements with dispersion encoded full range frequency domain optical coherence tomography in single- and multilayered weakly scattering phantoms
      In this study, depth resolved measurements of absorption profiles in the wavelength range of 800 nm with a bandwidth of 140 nm are demonstrated using high speed spectroscopic frequency domain OCT(SOCT) and a full range reconstruction algorithm (dispersion encoded full range, DEFR). The feasibility of the algorithm for SOCT is tested in simulation and experiment. With proper calibration, SOCT with DEFR is able to extract absolute, depth resolved absorption ...
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  2. About Bern University of Applied Sciences

    Bern University of Applied Sciences

    Bern University of Applied Sciences (BUAS) is situated in the canton of Bern which hosts the Swiss capital of the same name. The BUAS comprises six departments in various locations in Bern, Biel/Bienne, Burgdorf, Magglingen/ Maccolin and Zollikofen.  Switzerland also stands for a high quality of life and a safe living environment. Swiss hospitality and discretion makes a stay in this small country most enjoyable.  Also see OCT group website Here.