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    1. Mentioned In 137 Articles

    2. Retinal layer segmentation in a cohort of healthy children via optical coherence tomography

      Explore Journals | PLOS Ophthalmology
      Retinal layer segmentation in a cohort of healthy children via optical coherence tomography
      Background: High-resolution optical coherence tomography (OCT) allows the detection of macular pathology and involvement of the optic nerve in a wide spectrum of diseases. For the differentiation of diseased and healthy status, normal values of retinal layer segmentation are critical. Yet, normative values mostly cover adult populations with only sparse data for paediatric cohorts. We present data of retinal layer characteristics via OCT in a healthy paediatric cohort. Methods: This ...
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      Mentions: University of Bern

    3. Two Year Functional and Structural Changes-A Comparison between Trabeculectomy and XEN Microstent Implantation Using Spectral Domain Optical Coherence Tomography

      Explore MDPI Open Access Journals Platform Ophthalmology
      Two Year Functional and Structural Changes-A Comparison between Trabeculectomy and XEN Microstent Implantation Using Spectral Domain Optical Coherence Tomography
      The aim of this study was to analyze retinal nerve fiber layer (RNFL) thickness after trabeculectomy (TE) versus XEN microstent implantation (XEN) in primary open-angle glaucoma (POAG) cases nave to prior incisional glaucoma surgery. We examined 119 consecutive glaucoma patients retrospectively, who received a TE or XEN for medically uncontrolled POAG. Intraocular pressure (IOP), amount of IOP-lowering medication, mean deviation of standard automated perimetry and peripapillary RNFL thickness were evaluated ...
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      Mentions: University of Bern

    4. Novel Tomographical Bleb Classification Following ab-interno Implantation of Gel-Stent Using Anterior Segment Optical Coherence Tomography

      Explore LWW Online Ophthalmology
      Novel Tomographical Bleb Classification Following ab-interno Implantation of Gel-Stent Using Anterior Segment Optical Coherence Tomography
      Prcis: A novel qualitative tomographical classification for bleb following implantation of XEN-Gel-Stent using ab-interno approach is presented. Association of anatomical patterns to IOP and success rates illustrates that AS-OCT can be useful tool in clinical guidance. Purpose: To present a novel classification of bleb resulting from ab-interno implantation of XEN-Gel-Stent and report association of tomographical patterns with intraocular pressure (IOP) and success rates (SR). Materials and methods: A cross-sectional one-armed ...
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      Mentions: University of Bern

    5. Cynomolgus monkey’s choroid reference database derived from hybrid deep learning optical coherence tomography segmentation

      Explore Nature Publishing Group Ophthalmology
      Cynomolgus monkey’s choroid reference database derived from hybrid deep learning optical coherence tomography segmentation
      Cynomolgus monkeys exhibit human-like features, such as a fovea, so they are often used in non-clinical research. Nevertheless, little is known about the natural variation of the choroidal thickness in relation to origin and sex. A combination of deep learning and a deterministic computer vision algorithm was applied for automatic segmentation of foveolar optical coherence tomography images in cynomolgus monkeys. The main evaluation parameters were choroidal thickness and surface area ...
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      Mentions: University Hospital Zurich University of Bonn University of Bern

    6. Characteristic retinal atrophy pattern allows differentiation between pediatric MOGAD and MS after a single optic neuritis episode

      Explore Home - Springer Neurology , Ophthalmology
      Characteristic retinal atrophy pattern allows differentiation between pediatric MOGAD and MS after a single optic neuritis episode
      Background Optic neuritis (ON) is the most prevalent manifestation of pediatric multiple sclerosis (MS ped ) and myelin-oligodendrocyte glycoprotein antibody-associated disease (MOGAD ped ) in children6 years. In this study, we investigated retinal atrophy patterns and diagnostic accuracy of optical coherence tomography (OCT) in differentiating between both diseases after the first ON episode. Methods Patients were retrospectively identified in eight tertial referral centers. OCT, VEP and high/low-contrast visual acuity (HCVA/LCVA ...
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      Mentions: Medical University of Vienna University of Bern Ludwig-Maximilians University

    7. Comparison of Indocyanine Green Angiography and Swept-Source Wide-Field Optical Coherence Tomography Angiography in Posterior Uveitis

      Explore Frontiers Ophthalmology
      Comparison of Indocyanine Green Angiography and Swept-Source Wide-Field Optical Coherence Tomography Angiography in Posterior Uveitis
      Purpose: To compare indocyanine green angiography (ICGA) and swept-source wide-field optical coherence tomography angiography (SS-OCTA) for the assessment of patients with posterior uveitis. Method: SS-OCTA montage images of 5 x 12 x 12 mm or 2 x 15 x 9 mm, covering ~70-90 degree of the retina of consecutive patients with posterior uveitis were acquired. The choriocapillaries and choroidal slabs were compared to findings on ICGA. Results: Sixty-eight eyes of ...
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      Mentions: University of Bern

    8. No optical coherence tomography changes in premanifest Huntington's disease mutation carriers far from disease onset

      Explore Wiley Online Library Neurology , Ophthalmology
      No optical coherence tomography changes in premanifest Huntington's disease mutation carriers far from disease onset
      Background: Spectral-domain optical coherence tomography (OCT) may detect retinal changes as a biomarker in neurodegenerative diseases like manifest Huntington's disease (HD). We investigate macular retinal layer thicknesses in a premanifest HD (pre-HD) cohort and healthy controls (HC). Methods: Pre-HD mutation carriers underwent standardized ratings and a preset macular OCT scan. Thickness values were determined for each sector of all macular retinal layers, the mean of all sectors and the ...
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      Mentions: University of Bern

    9. Outer retinal features in OCT predict visual recovery after primary macula-involving retinal detachment repair

      Explore Journals | PLOS Ophthalmology
      Outer retinal features in OCT predict visual recovery after primary macula-involving retinal detachment repair
      Purpose To find predictive markers for the visual potential in optical coherence tomography (OCT) one month after surgical repair of macula-involving rhegmatogenous retinal detachment (miRD) with and without internal limiting membrane (ILM) peeling. Methods This retrospective single-center, single-surgeon cohort study included 74 patients who underwent pars plana vitrectomy (PPV) for primary miRD between January 2013 and August 2020 with follow-up examinations for at least 6 months. Patients developing recurrent detachments ...
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      Mentions: Heidelberg Engineering University of Bern

    10. Optical coherence tomography in coronary atherosclerosis assessment and intervention

      Explore Nature Publishing Group Cardiology
      Optical coherence tomography in coronary atherosclerosis assessment and intervention
      Since optical coherence tomography (OCT) was first performed in humans two decades ago, this imaging modality has been widely adopted in research on coronary atherosclerosis and adopted clinically for the optimization of percutaneous coronary intervention. In the past 10 years, substantial advances have been made in the understanding of in vivo vascular biology using OCT. Identification by OCT of culprit plaque pathology could potentially lead to a major shift in ...
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      Mentions: Brigham and Women’s Hospital Johns Hopkins University Massachusetts Institute of Technology

    11. Effect of Evolocumab on Coronary Plaque Phenotype and Burden in Statin-Treated Patients Following Myocardial Infarction

      Explore ScienceDirect Cardiology
      Effect of Evolocumab on Coronary Plaque Phenotype and Burden in Statin-Treated Patients Following Myocardial Infarction
      Objectives The purpose of this study was to determine the effect of evolocumab on optical coherence tomography (OCT) measures of plaque composition. Background The proprotein convertase subtilisin kexin type-9 inhibitor evolocumab produced coronary atheroma regression in statin-treated patients. Methods Patients with a nonST-segment elevation myocardial infarction were treated with monthly evolocumab 420 mg (n = 80) or placebo (n = 81) for 52 weeks. Patients underwent serial OCT and intravascular ultrasound imaging ...
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      Mentions: Cleveland Clinic University of Bern Semmelweis University

    12. Recommendations for OCTA reporting in retinal vascular disease: A Delphi approach by International Experts

      Explore ScienceDirect Ophthalmology
      Recommendations for OCTA reporting in retinal vascular disease: A Delphi approach by International Experts
      Purpose: To develop a consensus nomenclature for reporting optical coherence tomography angiography (OCTA) findings in retinal vascular disease (e.g., diabetic retinopathy, retinal vein occlusion) by international experts. Design: Delphi-based survey SUBJECTS, PARTICIPANTS AND/OR CONTROLS: Twenty-five retinal vascular disease and OCTA imaging experts METHODS, INTERVENTION, OR TESTING: A Delphi method of consensus development was used, comprising two rounds of online questionnaires, followed by a face-to-face meeting conducted virtually. Twenty-five ...
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      Mentions: University of Wisconsin University of Chicago University of Toronto

    14. Towards a better understanding of the posttreatment hemodynamic behaviors in femoropopliteal arteries through personalized computational models based on OCT images

      Explore Nature Publishing Group Cardiology
      Towards a better understanding of the posttreatment hemodynamic behaviors in femoropopliteal arteries through personalized computational models based on OCT images
      The hemodynamic behavior following endovascular treatment of patients with peripheral arterial disease plays a significant role on the occurrence of restenosis in femoro-popliteal (FP) arteries. The atheroprone flow conditions that are generally accepted to promote restenosis can be calculated by computational fluid dynamics (CFD) analyses, and these results can be used to assess individualized treatment outcomes. However, the impact of endovascular therapy on the flow behaviors of FP arteries are ...
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      Mentions: University of Bern

    15. Coronary embolism due to possible thrombosis of prosthetic aortic valve - the role of optical coherence tomography: case report

      Explore Journals Cardiology
      Coronary embolism due to possible thrombosis of prosthetic aortic valve - the role of optical coherence tomography: case report
      Background: Coronary embolism is an important non-atherosclerotic cause of acute myocardial infarction (AMI) that requires an individualized diagnostic and therapeutic approach. Although certain angiographic criteria exist that render an embolic origin likely, uncertainty remains. Optical coherence tomography (OCT) is a high-resolution intracoronary imaging technology that enables visualization of thrombus and the underlying coronary vessel wall, which may be helpful to distinguish between an atherosclerotic and non-atherosclerotic origin of AMI. Case ...
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      Mentions: University of Bern

    16. Impact of intracoronary optical coherence tomography in routine clinical practice: A contemporary cohort study

      Explore ScienceDirect Cardiology
      Impact of intracoronary optical coherence tomography in routine clinical practice: A contemporary cohort study
      Background/purpose: Guidelines recommend intracoronary optical coherence tomography (OCT) to assess stent failure and guide percutaneous coronary intervention (PCI) but OCT may be useful for other indications in routine clinical practice. Methods/materials: We conducted an international registry of OCT cases at two large tertiary care centers to assess clinical indications and the potential impact on decision making of OCT in clinical routine. Clinical indications, OCT findings, and their impact ...
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      Mentions: University of Bern
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    University of Bern offers top quality across the board: it enjoys special recognition in leading-edge disciplines, is reputed for the excellent quality of its teaching, offers a delightful setting, and a campus environment intimately linked to the social, economic and political life of the city.

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