1. Baylor College of Medicine

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    1. Mentioned In 140 Articles

    2. Anterior Segment Optical Coherence Tomography of Ocular Cystinosis Confirmed by Electron Microscopy

      Anterior Segment Optical Coherence Tomography of Ocular Cystinosis Confirmed by Electron Microscopy
      Purpose: To report a case of ocular cystinosis diagnosed by anterior segment optical coherence tomography (AS-OCT) and histopathology. Methods: A 67-year-old man who presented with eye pain was found to have unilateral corneal crystal deposition. Ocular cystinosis was diagnosed by histopathology, AS-OCT, and lack of renal involvement of the disease. Results: AS-OCT showed hyperreflective densities in the corneal epithelium. The patient underwent superficial keratectomy given irregular astigmatism prior to cataract ...
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    3. Assessing the Acute Effects of Prenatal Synthetic Cannabinoid Exposure on Murine Fetal Brain Vasculature Using Optical Coherence Tomography

      Assessing the Acute Effects of Prenatal Synthetic Cannabinoid Exposure on Murine Fetal Brain Vasculature Using Optical Coherence Tomography
      Marijuana is one of the most commonly abused substances during pregnancy. Synthetic cannabinoids (SCBs) are a group of heterogeneous compounds that are 40‐ to 600‐fold more potent than ∆ 9 ‐tetrahydrocannabinol , the major psychoactive component of marijuana. With SCBs being legally available for purchase and the prevalence of unplanned pregnancies, the possibility of prenatal exposure to SCBs is high. However, the effects of prenatal SCB exposure on embryonic brain development ...
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    4. Architecture evaluation of the main clear corneal incisions in femtosecond laser-assisted cataract surgery by optical coherence tomography imaging

      Architecture evaluation of the main clear corneal incisions in femtosecond laser-assisted cataract surgery by optical coherence tomography imaging
      ...ba Ophthalmologic Hospital, João Pessoa, Paraíba, Brazil; 4Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA; 5São Paulo University School of Medicine (FM-USP), Department of...
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    5. Assessing the biomechanical properties of the porcine crystalline lens as a function of intraocular pressure with optical coherence elastography

      Assessing the biomechanical properties of the porcine crystalline lens as a function of intraocular pressure with optical coherence elastography
      In this study, we investigated the relationship between the biomechanical properties of the crystalline lens and intraocular pressure (IOP) using a confocal acoustic radiation force (ARF) and phase-sensitive optical coherence elastography (OCE) system. ARF induced a small displacement at the apex of porcine lenses in situ at various artificially controlled IOPs. Maximum displacement, relaxation rate, and Youngs modulus were utilized to assess the stiffness of the crystalline lens. The results ...
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    6. Postdoctoral and Research Scientist Positions in Biomedical Imaging at Baylor College of Medicine

      Postdoctoral and Research Scientist Positions in Biomedical Imaging at Baylor College of Medicine
      ..., resources and opportunities toward diverse scientific careers. In addition, postdoctoral researchers at the Baylor College of Medicine are provided with a highly developed Career Development Series organized by our hig...
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    7. Modified wavelength scanning interferometry for simultaneous tomography and topography of the cornea with Fourier domain optical coherence tomography

      Modified wavelength scanning interferometry for simultaneous tomography and topography of the cornea with Fourier domain optical coherence tomography
      Visual acuity is dependent on corneal shape and size. A minor variation in surface geometry can cause a deformation of corneal geometry, which affects its optical performance. In this work we demonstrate an algorithm for the simultaneous measurement of corneal tomography and topography with a traditional point-scanning Fourier domain optical coherence tomography (FD-OCT) system. A modified wavelength scanning interferometry (mWSI) algorithm enabled topographical evaluation of the surface with nanometer-scale resolution ...
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    8. In Vivo Imaging of the Mouse Reproductive Organs, Embryo Transfer, and Oviduct Cilia Dynamics Using Optical Coherence Tomography

      In Vivo Imaging of the Mouse Reproductive Organs, Embryo Transfer, and Oviduct Cilia Dynamics Using Optical Coherence Tomography
      The oviduct (or fallopian tube) serves as the site where a number of major reproductive events occur for the start of a new life in mammals. Understanding the oviduct physiology is essential to uncover hidden mechanisms of the human reproduction and its disorders, yet the current analysis of the oviduct that is largely limited to in vitro imaging is a significant technical hurdle. To overcome this barrier, we have recently ...
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    9. In vivo three-dimensional tracking of sperm behaviors in the mouse oviduct

      In vivo three-dimensional tracking of sperm behaviors in the mouse oviduct
      Mammalian sperm evolutionarily acquired complex mechanisms regulating their behaviors, which are thought to be critical in navigating through the female reproductive tract toward fertilization. However, all current knowledge of this process is largely extrapolated from in vitro and ex vivo studies, because in vivo analysis of sperm in their native fertilization environment has not been possible. Here we report a functional optical coherence tomography approach that allows, for the first ...
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    10. Functional optical coherence tomography for live dynamic analysis of mouse embryonic cardiogenesis

      Functional optical coherence tomography for live dynamic analysis of mouse embryonic cardiogenesis
      Blood flow, heart contraction, and tissue stiffness are important regulators of cardiac morphogenesis and function during embryonic development. Defining how these factors are integrated is critically important to advance prevention, diagnostics, and treatment of congenital heart defects. Mammalian embryonic development is taking place deep within the female body, which makes cardiodynamic imaging and analysis during early developmental stages in humans inaccessible. With thousands of mutant lines available and well-established genetic ...
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  2. About Baylor College of Medicine

    Baylor College of Medicine

    Baylor College of Medicine, located in Houston, Texas, USA, is one of the world's leading centers for biomedical research and clinical care. Situated within the Texas Medical Center, a 1,000-acre complex that is home to 46 member institutions and is the largest medical center in the world, Baylor College of Medicine has affiliations with eight teaching hospitals, including the world-renowned Texas Children's Hospital, MD Anderson Cancer Center, Menninger Clinic and Texas Heart Institute. It has been consistently rated the top medical school in Texas and among the top 10 medical schools in the United States. Its Graduate School of Biomedical Sciences is also highly rated. BCM, despite being solely focused on medical and graduate education, has become one of 63 American colleges with an endowment greater than $1 billion.