1. Baylor College of Medicine

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    1. Mentioned In 173 Articles

    2. Mouse embryo phenotyping with optical coherence tomography

      Mouse embryo phenotyping with optical coherence tomography
      With the explosion of gene editing tools in recent years, there has been a much greater demand for mouse embryo phenotyping, and traditional methods such as histology and histochemistry experienced a methodological renaissance as they became the principal tools for phenotyping. However, it is important to explore alternative phenotyping options to maximize time and resources and implement volumetric structural analysis for enhanced investigation of phenotypes. Cardiovascular phenotyping, in particular, is ...
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    3. Baseline Microperimetry and OCT in the RUSH2A Study: Structure-Function Association and Correlation with Disease Severity

      Baseline Microperimetry and OCT in the RUSH2A Study: Structure-Function Association and Correlation with Disease Severity
      Purpose: To investigate baseline mesopic microperimetry (MP) and spectral domain optical coherence tomography (OCT) in the Rate of Progression in USH2A-related Retinal Degeneration (RUSH2A) study. Design: Natural history study SETTING: 16 clinical sites in Europe and North America STUDY POPULATION: Participants with Usher syndrome type 2 (USH2) (N=80) or autosomal recessive nonsyndromic RP (ARRP) (N=47) associated with biallelic disease-causing sequence variants in USH2A. Observation procedures: General linear models ...
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    4. First interobserver agreement of optical coherence tomography in the bile duct: A multicenter collaborative study

      First interobserver agreement of optical coherence tomography in the bile duct: A multicenter collaborative study
      Background and study aims Optical coherence tomography (OCT) is a new technology available for evaluation of indeterminate biliary strictures. It allows under-the-surface visualization and preliminary studies have confirmed standardized characteristics associated with malignancy. The aim of this study is to evaluate the first interobserver agreement in identifying previously agreed upon OCT criteria and diagnosing of malignant versus benign disease. Patients and methods Fourteen endoscopists were asked to review an atlas ...
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    5. Following the Beat: Imaging the Valveless Pumping Function in the Early Embryonic Heart

      Following the Beat: Imaging the Valveless Pumping Function in the Early Embryonic Heart
      In vertebrates, the coordinated beat of the early heart tube drives cardiogenesis and supports embryonic growth. How the heart pumps at this valveless stage marks a fascinating problem that is of vital significance for understanding cardiac development and defects. The developing heart achieves its function at the same time as continuous and dramatic morphological changes, which in turn modify its pumping dynamics. The beauty of this muti-time-scale process also highlights ...
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    6. Dynamic volumetric imaging and cilia beat mapping in the mouse male reproductive tract with optical coherence tomography

      Dynamic volumetric imaging and cilia beat mapping in the mouse male reproductive tract with optical coherence tomography
      Spermatozoa transport within the male reproductive tract is a highly dynamic and biologically important reproductive event. However, due to the lack of live volumetric imaging technologies and quantitative measurements, there is little information on the dynamic aspect and regulation of this process. Here, we presented ex vivo dynamic volumetric imaging of the mouse testis, efferent duct, epididymis, and vas deferens at a micro-scale spatial resolution with optical coherence tomography (OCT ...
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    7. Introduction to optical coherence elastography: tutorial

      Introduction to optical coherence elastography: tutorial
      Optical coherence elastography (OCE) has seen rapid growth since its introduction in 1998. The past few decades have seen tremendous advancements in the development of OCE technology and a wide range of applications, including the first clinical applications. This tutorial introduces the basics of solid mechanics, which form the foundation of all elastography methods. We then describe how OCE measurements of tissue motion can be used to quantify tissue biomechanical ...
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    8. Optical Coherence Tomography and Visual Evoked Potential Testing for Noninvasive Intracranial Pressure Monitoring in Craniosynostosis

      Optical Coherence Tomography and Visual Evoked Potential Testing for Noninvasive Intracranial Pressure Monitoring in Craniosynostosis
      Elevated intracranial pressure is sometimes observed in the setting of craniosynostosis. Common clinical symptoms include headaches, nausea, vomiting, developmental delays, and visual disturbances. 1 Some of these symptoms may be mild and unspecific in the pediatric population. In other cases, pediatric patients can present late for evaluation by the craniofacial surgeon with more concerning signs of intracranial hypertension. 2 Fundoscopic examination is commonly utilized for noninvasive evaluation of elevated intracranial ...
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    9. Multimodal imaging system combining optical coherence tomography and Brillouin microscopy for neural tube imaging

      Multimodal imaging system combining optical coherence tomography and Brillouin microscopy for neural tube imaging
      To understand the dynamics of tissue stiffness during neural tube formation and closure in a murine model, we have developed a multimodal, coaligned imaging system combining optical coherence tomography (OCT) and Brillouin microscopy. Brillouin microscopy can map the longitudinal modulus of tissue but cannot provide structural images. Thus, it is limited for imaging dynamic processes such as neural tube formation and closure. To overcome this limitation, we have combined Brillouin ...
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    10. Perimeter Medical Imaging AI Announces Initiation of First Clinical Trial Site at West Cancer Center & Research Institute in Tennessee

      Perimeter Medical Imaging AI Announces Initiation of First Clinical Trial Site at West Cancer Center & Research Institute in Tennessee
      ... clinical sites will participate in the pivotal study led by Principal Investigator, Dr. Alastair Thompson at Baylor College of Medicine, with study completion anticipated by the end of 2022. About Perimeter S-Series OC...
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    11. Perimeter Medical Imaging AI Announces Important Milestone in Atlas Ai Project With FDA Investigational Device Exemption (IDE) Approval to Launch Clinical Trial Using Perimeter B-Series OCT With ImgAssist AI in Breast Conservation Surgery

      Perimeter Medical Imaging AI Announces Important Milestone in Atlas Ai Project With FDA Investigational Device Exemption (IDE) Approval to Launch Clinical Trial Using Perimeter B-Series OCT With ImgAssist AI in Breast Conservation Surgery
      ...rincipal Investigator and Professor, Section Chief of Breast Surgery and Olga Keith Wiess Chair of Surgery at Baylor College of Medicine and the Dan L Duncan Comprehensive Cancer Center said, “Currently, approximately on...
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    12. Ultra-fast dynamic line-field optical coherence elastography

      Ultra-fast dynamic line-field optical coherence elastography
      Abstract In this work, we present an ultra-fast line-field optical coherence elastography system (LF-OCE) with an 11.5 MHz equivalent A-line rate. The system was composed of a line-field spectral domain optical coherence tomography system based on a supercontinuum light source, Michelson-type interferometer, and a high-speed 2D spectrometer. The system performed ultra-fast imaging of elastic waves in tissue-mimicking phantoms of various elasticities.
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    13. Multimodal high-resolution embryonic imaging with light sheet fluorescence microscopy and optical coherence tomography

      Multimodal high-resolution embryonic imaging with light sheet fluorescence microscopy and optical coherence tomography
      A high-resolution imaging system combining optical coherence tomography (OCT) and light sheet fluorescence microscopy (LSFM) was developed. LSFM confined the excitation to only the focal plane, removing the out of plane fluorescence. This enabled imaging a murine embryo with higher speed and specificity than traditional fluorescence microscopy. OCT gives information about the structure of the embryo from the same plane illuminated by LSFM. The co-planar OCT and LSFM instrument was ...
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    14. In vivo dynamic 3D imaging of oocytes and embryos in the mouse oviduct

      In vivo dynamic 3D imaging of oocytes and embryos in the mouse oviduct
      Developmental biologists have always relied on imaging to shed light on dynamic cellular events. However, processes such as mammalian fertilization and embryogenesis are generally inaccessible for direct imaging. In consequence, how the oviduct (fallopian tube) facilitates the transport of gametes and preimplantation embryos continues to be unanswered. Here we present a combination of intravital window and optical coherence tomography for dynamic, volumetric, in vivo imaging of oocytes and embryos as ...
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    15. 1-15 of 173 1 2 3 4 ... 10 11 12 »
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  2. About Baylor College of Medicine

    Baylor College of Medicine

    Baylor College of Medicine, located in Houston, Texas, USA, is one of the world's leading centers for biomedical research and clinical care. Situated within the Texas Medical Center, a 1,000-acre complex that is home to 46 member institutions and is the largest medical center in the world, Baylor College of Medicine has affiliations with eight teaching hospitals, including the world-renowned Texas Children's Hospital, MD Anderson Cancer Center, Menninger Clinic and Texas Heart Institute. It has been consistently rated the top medical school in Texas and among the top 10 medical schools in the United States. Its Graduate School of Biomedical Sciences is also highly rated. BCM, despite being solely focused on medical and graduate education, has become one of 63 American colleges with an endowment greater than $1 billion.