1. Audrey K. Ellerbee

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    1. Mentioned In 42 Articles

    2. Postdoctoral Fellow: Biophotonics and Computer Vision Stanford University, Stanford, CA

      Postdoctoral Fellow: Biophotonics and Computer Vision Stanford University, Stanford, CA
      The Stanford Biomedical Optics Group (http://sbo.stanford.edu), in close collaboration with clinical researchers in the School of Medicine (urology), seeks highly motivated research associate with excellent computer programming and image processing skills along with a good background / strong interest in optics, microscopy or medical imaging and interest or experience in computer vision. Stanford University provides an outstanding environment for solid technical research with clinical impact. Applicants will work ...
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    3. Registration of free-hand OCT daughter endoscopy to 3D organ reconstruction

      Registration of free-hand OCT daughter endoscopy to 3D organ reconstruction
      Despite the trend to pair white light endoscopy with secondary image modalities for in vivo characterization of suspicious lesions, challenges remain to co-register such data. We present an algorithm to co-register two different optical imaging modalities as a mother-daughter endoscopy pair. Using white light cystoscopy (mother) and optical coherence tomography (OCT) (daughter) as an example, we developed the first forward-viewing OCT endoscope that fits in the working channel of flexible ...
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    4. Combined optical coherence tomography and hyperspectral imaging using a double-clad fiber coupler

      Combined optical coherence tomography and hyperspectral imaging using a double-clad fiber coupler
      This work demonstrates the combination of optical coherence tomography (OCT) and hyperspectral imaging (HSI) using a double-clad optical fiber coupler. The single-mode core of the fiber is used for OCT imaging, while the inner cladding of the double-clad fiber provides an efficient way to capture the reflectance spectrum of the sample. The combination of both methods enables three-dimensional acquisition of the sample morphology with OCT, enhanced with complementary molecular information ...
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    5. Postdoctoral Associate: Biophotonics and Computer Vision Stanford University, Stanford, CA

      Postdoctoral Associate: Biophotonics and Computer Vision Stanford University, Stanford, CA
      The Stanford Biomedical Optics Group (http://sbo.stanford.edu), in close collaboration with clinical researchers in the School of Medicine (urology), seeks highly motivated postdoctoral candidates with excellent computer programming and image processing skills along with a good background in optics, microscopy or medical imaging and interest or experience in computer vision. Stanford University provides an outstanding environment for solid technical research with clinical impact. Applicants will work closely with ...
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    6. Classification of basal cell carcinoma in human skin using machine learning and quantitative features captured by polarization sensitive optical coherence tomography

      Classification of basal cell carcinoma in human skin using machine learning and quantitative features captured by polarization sensitive optical coherence tomography
      We report the first fully automated detection of basal cell carcinoma (BCC), the most commonly occurring type of skin cancer, in human skin using polarization-sensitive optical coherence tomography (PS-OCT). Our proposed automated procedure entails building a machine-learning based classifier by extracting image features from the two complementary image contrasts offered by PS-OCT, intensity and phase retardation (PR), and selecting a subset of features that yields a classifier with the highest ...
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    7. Multimodal 3D cancer-mimicking optical phantom

      Multimodal 3D cancer-mimicking optical phantom
      Three-dimensional (3D) organ-mimicking phantoms provide realistic imaging environments for testing various aspects of optical systems, including for evaluating new probe designs, characterizing the diagnostic potential of new technologies, and assessing novel image processing algorithms prior to validation in real tissue. We introduce and characterize the use of a new material, Dragon Skin (Smooth-On Inc.), and fabrication technique, air-brushing, for fabrication of a 3D phantom that mimics the appearance of a ...
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    8. Combined optical coherence tomography and hyper-spectral imaging using a double clad fiber coupler

      Combined optical coherence tomography and hyper-spectral imaging using a double clad fiber coupler
      This proceedings shows the combination of Optical Coherence Tomography (OCT) and Hyper-Spectral Imaging (HSI) using a double-clad optical fiber. The single mode core of the fiber is used to transmit OCT signals, while the cladding, with its large collection area, provides an efficient way to capture the reflectance spectrum of the sample. The combination of both methods enables three-dimensional acquisition of sample morphology with OCT, enhanced by the molecular information ...
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    9. Iterative re-weighted approach to high-resolution optical coherence tomography with narrow-band sources

      Iterative re-weighted approach to high-resolution optical coherence tomography with narrow-band sources
      Optical coherence tomography (OCT) is a non-invasive optical imaging modality capable of high resolution imaging of internal tissue structures. It is widely believed that the high axial resolution in OCT systems requires a wide-bandwidth light source. As a result, often the potential advantages of narrow-bandwidth sources (in terms of cost and/or imaging speed) are understood to come at the cost of significant reduction in imaging resolution. In this paper ...
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    10. Automated, Depth-Resolved Estimation of the Attenuation Coefficient From Optical Coherence Tomography Data

      Automated, Depth-Resolved Estimation of the Attenuation Coefficient From Optical Coherence Tomography Data
      We present a method for automated, depth-resolved extraction of the attenuation coefficient from Optical Coherence Tomography (OCT) data. In contrast to previous automated, depth-resolved methods, the Depth-Resolved Confocal (DRC) technique derives an invertible mapping between the measured OCT intensity data and the attenuation coefficient while considering the confocal function and sensitivity fall-off, which are critical to ensure accurate measurements of the attenuation coefficient in practical settings (e.g., clinical endoscopy ...
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    11. Label-free characterization of vitrification-induced morphology changes in single-cell embryos with full-field optical coherence tomography

      Label-free characterization of vitrification-induced morphology changes in single-cell embryos with full-field optical coherence tomography
      Vitrification is an increasingly popular method of embryo cryopreservation that is used in assisted reproductive technology. Although vitrification has high post-thaw survival rates compared to other freezing techniques, its long-term effects on embryo development are still poorly understood. We demonstrate an application of full-field optical coherence tomography (FF-OCT) to visualize the effects of vitrification on live single-cell (2 pronuclear) mouse embryos without harmful labels. Using FF-OCT, we observed that vitrification ...
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    12. Fabrication of healthy and disease-mimicking retinal phantoms with tapered foveal pits for optical coherence tomography

      Fabrication of healthy and disease-mimicking retinal phantoms with tapered foveal pits for optical coherence tomography
      Optical coherence tomography (OCT) has become a standard tool in ophthalmology clinics for diagnosing many retinal diseases. Nonetheless, the technical and clinical communities still lack a standardized phantom that could aid in evaluating and normalizing the many protocols and systems used for diagnosis. Existing retinal phantoms are able to mimic the thickness and scattering properties of the retinal layers but are unable to model the morphology of the foveal pit ...
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    13. Automated, Depth Resolved Estimation of the Attenuation Coefficient From Optical Coherence Tomography Data

      Automated, Depth Resolved Estimation of the Attenuation Coefficient From Optical Coherence Tomography Data
      We present a method for automated , depth - resolved extraction of the attenuation coefficient from Optical Coherence Tomography (OCT) data . In contrast to previous automated , depth - resolved methods, the Depth - Resolved Confocal (DRC) technique derives an invertible mapping between the measured OCT intensity data and the attenuation coefficient while considering the confocal function and sensitivity fall-off, which are critical to ensure accurate measurements of the attenuation coefficient in practical settings (e ...
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    14. Rapid scanning catheterscope for expanded forward-view volumetric imaging with optical coherence tomography

      Rapid scanning catheterscope for expanded forward-view volumetric imaging with optical coherence tomography
      We demonstrate a novel catheterscope, based on scanning fiber endoscopy, for volumetric imaging with optical coherence tomography (OCT), which possesses a high resonance frequency ( 2 kHz ) and a small outer diameter (OD) (1.07 mm). Our design is the fastest volumetric-scanning, forward-viewing catheterscope for OCT, and the scanning package has the smallest OD of any such OCT package published to date. Using a proof-of-operation catheterscope with commercial lenses, we demonstrate ...
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    15. 1-15 of 42 1 2 3 »
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  2. About Audrey K. Ellerbee

    Audrey K. Ellerbee

    Audrey Ellerbee holds a BSE in Electrical Engineering from Princeton University and a PhD in Biomedical Engineering from Duke University; she completed her postdoctoral training at Harvard University. Dr. Ellerbee is the recipient of numerous honors and fellowships, including the National Science Foundation Graduate Research Fellowship, National Society of Black Engineers Graduate Student of the Year Award, the Arthur H. Guenther Congressional Fellowship and the Ford Foundation Postdoctoral Fellowship. Audrey officially joined Stanford University and the Ginzton Laboratory in September 2010, and is a member of the Optical Society of America and the SPIE.