1. Atsushi Tanaka

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    1. Mentioned In 62 Articles

    2. Prognosis of spontaneous coronary artery dissection treated by percutaneous coronary intervention with optical coherence tomography

      Prognosis of spontaneous coronary artery dissection treated by percutaneous coronary intervention with optical coherence tomography
      Background Although about half of patients with spontaneous coronary artery dissection (SCAD) face ongoing necrosis, conservative therapy is recommended due to a high complication rate in angiography-guided percutaneous coronary intervention (PCI). The aim of this study was to investigate clinical outcomes of SCAD treated by optical coherence tomography (OCT)-guided PCI. Methods This study consisted of consecutive 306 patients with acute coronary syndrome (ACS) who underwent OCT-guided PCI. Based on ...
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    3. Automatic Fibroatheroma Identification from Intravascular Optical Coherence Tomography Images

      Automatic Fibroatheroma Identification from Intravascular Optical Coherence Tomography Images
      Vulnerable plaque identification is important in coronary heart disease diagnosis. Intravascular Optical Coherence Tomography (IVOCT) is an imaging modality which can characterize the appearance of vulnerable plaques. However, current used manual reading of the images is time consuming and subjective. Therefore, an automated and objective assessment of the plaque is necessary. This paper proposes a method for automatic identification of potential vulnerable plaque such as fibroatheroma in IVOCT images. In ...
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    4. Optical Coherence Tomography Predictors for Edge Restenosis After Everolimus-Eluting Stent Implantation

      Optical Coherence Tomography Predictors for Edge Restenosis After Everolimus-Eluting Stent Implantation
      Background Stent edge restenosis (SER) remains a potential limitation of drug-eluting stents. The aim of this study was to determine optical coherence tomography (OCT) predictors for angiographic late SER after everolimus-eluting stent implantation. Methods and Results We retrospectively analyzed 319 patients who underwent OCT immediately after everolimus-eluting stent implantation and scheduled 9- to 12-month follow-up angiography. The binary angiographic SER rate was 10% (32/319) in the patients, 8.4 ...
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    5. Assessment of Vascular Response after Stent Implantation by Intracoronary Optical Coherence Tomograph

      Assessment of Vascular Response after Stent Implantation by Intracoronary Optical Coherence Tomograph
      Optical coherence tomography (OCT) is a high resolution (10-20 m) imaging modality that provides microscopic visualization of the coronary artery including vascular response after stent implantation. Compared to conventional intravascular ultrasound, OCT can more clearly identify findings immediately after stent implantation, such as tissue protrusion, stent edge dissection, and incomplete stent strut apposition. Furthermore, OCT allows clinicians to accurately assess the late acquired stent malapposition and strut coverage which could ...
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    6. Reduction of in-stent thrombus immediately after percutaneous coronary intervention by pretreatment with prasugrel compared with clopidogrel: An optical coherence tomography study

      Reduction of in-stent thrombus immediately after percutaneous coronary intervention by pretreatment with prasugrel compared with clopidogrel: An optical coherence tomography study
      Background Prasugrel is a new-generation thienopyridine antiplatelet agent that provides more consistent and prompt platelet inhibition than clopidogrel. The aim of this study was to compare in-stent thrombus inhibition effect of pretreatment with prasugrel and clopidogrel by using optical coherence tomography (OCT) immediately after percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS). Methods We performed OCT immediately after PCI in 108 ACS patients pretreated with either prasugrel ( n = 51 ...
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    7. Optical coherence tomography assessment of efficacy of thrombus aspiration in patients undergoing a primary percutaneous coronary intervention for acute ST-elevation myocardial infarction

      Optical coherence tomography assessment of efficacy of thrombus aspiration in patients undergoing a primary percutaneous coronary intervention for acute ST-elevation myocardial infarction
      Objective: We used optical coherence tomography (OCT) to assess the impact of thrombus aspiration before angioplasty on poststenting tissue protrusions in patients undergoing a primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI). Methods and results: A total of 188 patients with STEMI who underwent thrombus-aspiration PCI ( n =113) or standard PCI ( n =75) were examined in this study. OCT was performed immediately after primary PCI to assess ...
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    8. Optical coherence tomography assessment of efficacy of thrombus aspiration in patients undergoing a primary percutaneous coronary intervention for acute ST-elevation myocardial infarction

      Optical coherence tomography assessment of efficacy of thrombus aspiration in patients undergoing a primary percutaneous coronary intervention for acute ST-elevation myocardial infarction
      Objective: We used optical coherence tomography (OCT) to assess the impact of thrombus aspiration before angioplasty on poststenting tissue protrusions in patients undergoing a primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI). Methods and results: A total of 188 patients with STEMI who underwent thrombus-aspiration PCI ( n =113) or standard PCI ( n =75) were examined in this study. OCT was performed immediately after primary PCI to assess ...
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    9. Multi-laboratory inter-institute reproducibility study of IVOCT and IVUS assessments using published consensus document definitions

      Multi-laboratory inter-institute reproducibility study of IVOCT and IVUS assessments using published consensus document definitions
      Aims The aim of this study was to investigate the reproducibility of intravascular optical coherence tomography (IVOCT) assessments, including a comparison to intravascular ultrasound (IVUS). Intra-observer and inter-observer variabilities of IVOCT have been previously described, whereas inter-institute reliability in multiple laboratories has never been systematically studied. Methods and results In 2 independent laboratories with intravascular imaging expertise, 100 randomized matched data sets of IVOCT and IVUS images were analysed by ...
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    10. Optimal threshold of postintervention minimum stent area to predict in-stent restenosis in small coronary arteries: An optical coherence tomography analysis

      Optimal threshold of postintervention minimum stent area to predict in-stent restenosis in small coronary arteries: An optical coherence tomography analysis
      Objectives The aim of this study was to determine the best threshold of postintervention minimum stent area (MSA) assessed by optical coherence tomography (OCT) to predict long-term in-stent restenosis (ISR) for 2.5 mm-diameter everolimus-eluting stents (EES). Background Percutaneous coronary intervention (PCI) for small coronary arteries remains challenging. Stent underexpansion is a strong predictor of late ISR. Methods We performed a retrospective analysis of 69 lesions in 69 patients undergoing ...
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    11. Vasa Vasorum Restructuring in Human Atherosclerotic Plaque Vulnerability

      Vasa Vasorum Restructuring in Human Atherosclerotic Plaque Vulnerability
      Background Previous studies have suggested that vasa vasorum (VV) is associated with plaque progression and vulnerability. Objectives The aim of this study was to investigate the relationship between coronary neovascularization structures and plaque characteristics. Methods We included 53 patients who underwent optical coherence tomography to observe the proximal left anterior descending coronary artery. Patients were classified into 5 groups according to lesion characteristics: normal; fibrous plaque (FP); fibroatheroma (FA); plaque ...
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    12. Optimizing flushing parameters in intracoronary optical coherence tomography: an in vivo swine study

      Optimizing flushing parameters in intracoronary optical coherence tomography: an in vivo swine study
      Intracoronary optical frequency domain imaging (OFDI), requires the displacement of blood for clear visualization of the artery wall. Radiographic contrast agents are highly effective at displacing blood however, may increase the risk of contrast-induced nephropathy. Flushing media viscosity, flow rate, and flush duration influence the efficiency of blood displacement necessary for obtaining diagnostic quality OFDI images. The aim of this work was to determine the optimal flushing parameters necessary to ...
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    13. Comparison of vascular response between everolimus-eluting stent and bare metal stent implantation in ST-segment elevation myocardial infarction assessed by optical coherence tomography

      Comparison of vascular response between everolimus-eluting stent and bare metal stent implantation in ST-segment elevation myocardial infarction assessed by optical coherence tomography
      Aims The long-term safety of second-generation everolimus-eluting stents (EESs) in ST-segment elevation myocardial infarction (STEMI) remains unclear. The aim of this study was to evaluate the late vascular response after stent implantation in STEMI between EES and bare-metal stent (BMS) by using optical coherence tomography (OCT). Methods and results A prospective OCT examination was performed in 102 patients at 10 months after stent implantation for treatment of STEMI. A total ...
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    14. Effect of Atorvastatin Therapy on Fibrous Cap Thickness in Coronary Atherosclerotic Plaque as Assessed by Optical Coherence Tomography The EASY-FIT Study

      Effect of Atorvastatin Therapy on Fibrous Cap Thickness in Coronary Atherosclerotic Plaque as Assessed by Optical Coherence Tomography The EASY-FIT Study
      ...D^∗; Takashi Tanimoto, MD, PhD^∗; Yasushi Ino, MD, PhD^∗; Tomoyuki Yamaguchi, MD^∗; Hirata Kumiko, MD, PhD^∗; Atsushi Tanaka, MD, PhD^†; Toshio Imanishi, MD, PhD^∗; Hideharu Akagi, MD, PhD^†; Takashi Akasaka, MD, PhD^∗ ...
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    15. Automatic atherosclerotic heart disease detection in intracoronary optical coherence tomography images

      Automatic atherosclerotic heart disease detection in intracoronary optical coherence tomography images
      Intracoronary optical coherence tomography (OCT) is a new invasive imaging system which produces highresolution images of coronary arteries. Preliminary data suggests that the atherosclerotic disease can be detected from the intracoronary OCT images. However, manual assessment of the intracoronary OCT images is time-consuming and subjective. In this work, we present an automatic atherosclerotic disease detection system on intracoronary OCT images. In the system, a preprocessing scheme is first applied to ...
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  2. About Atsushi Tanaka

    Atsushi Tanaka is at the department of Cardiovascular Medicine, Wakayama Medical University.