1. Asan Medical Center

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    1. Mentioned In 53 Articles

    2. Relationship between the Lamina Cribrosa, Outer Retina, and Choroidal Thickness as Assessed Using Spectral Domain Optical Coherence Tomography

      Relationship between the Lamina Cribrosa, Outer Retina, and Choroidal Thickness as Assessed Using Spectral Domain Optical Coherence Tomography
      ...lege of Medicine, Seoul, Korea. ^ Corresponding Author: Kyung Rim Sung, MD, PhD. Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, #88 Olympic-ro 43-gil, Songpa-gu, Seoul 138-736,...
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    3. Usefulness of optical coherence tomography to detect central serous chorioretinopathy in monkeys

      Usefulness of optical coherence tomography to detect central serous chorioretinopathy in monkeys

      Many systemic drugs can induce ocular toxicity and several ocular side-effects have been identified in clinical studies. However, it is difficult to detect ocular toxicity in preclinical studies because of the lack of appropriate evaluation methods. Optical coherence tomography (OCT) is useful because it can provide real-time images throughout a study period, whereas histopathology only provides images of sacrificed animals. Using OCT alongside histopathology, attempts were made to find effective approaches for screening of drug-induced ocular toxicity in monkeys. Such approaches could be used in preclinical studies prior to human trials. Six male cynomolgus monkeys ( Macaca fascicularis Raffles ) were orally ...

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    4. Pancoronary Plaque Vulnerability in Patients with Acute Coronary Syndrome and Ruptured Culprit Plaque: A Three-Vessel Optical Coherence Tomography Study

      Pancoronary Plaque Vulnerability in Patients with Acute Coronary Syndrome and Ruptured Culprit Plaque: A Three-Vessel Optical Coherence Tomography Study

      Background Recent studies described different clinical and underlying plaque characteristics between patients with and without plaque rupture presenting with acute coronary syndrome (ACS). In light of the systemic nature of atherosclerosis, we hypothesized that non-culprit plaques might also express different morphological features in these two groups of patients. Methods Thirty-eight patients with ACS who underwent 3-vessel optical coherence tomography (OCT) imaging were identified from the Massachusetts General Hospital OCT Registry. Based on culprit plaque morphology, the study population was divided into two groups: patients with plaque rupture at the culprit lesion (Group 1), and patients with non-ruptured plaque at the ...

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    5. Comparison of OCT Measurements between High Myopic and Low Myopic Children

      Comparison of OCT Measurements between High Myopic and Low Myopic Children

      Purpose: To compare the peripapillary retinal nerve fiber layer (RNFL) thickness, macular thickness, and total macular volume of high myopic eyes with those of low myopic eyes in children younger than 10 years. Methods: Prospective, randomized, comparative study. Time-domain optical coherence tomography (OCT) (Stratus OCT; Carl Zeiss Meditec) was performed on 15 children with high myopia (refractive error greater than or equal to -6.0 diopters [D], group 1) and 20 children with low myopia (0 less than refractive error from -0.25 to -3.0 D, group 2). Fast RNFL scan and a fast macular scan with OCT were ...

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    6. Features of Coronary Plaque in Patients with Metabolic Syndrome and Diabetes Mellitus Assessed by 3-vessel Optical Coherence Tomography

      Features of Coronary Plaque in Patients with Metabolic Syndrome and Diabetes Mellitus Assessed by 3-vessel Optical Coherence Tomography

      Background —The pathophysiologic basis for the association between metabolic syndrome (MetS) and coronary artery disease is not well understood. We sought to characterize coronary plaques in patients with MetS using optical coherence tomography (OCT). Methods and Results —We identified 451 coronary plaques from 171 subjects who underwent OCT imaging in three coronary arteries. Subjects were divided into 3 groups: diabetes mellitus (DM, n=77), MetS (n=35), and a control group (C group, n=59) without DM or MetS. OCT analysis included the presence of lipid-rich plaque, maximum lipid arc, lipid-core length (LL), lipid index (LI), fibrous cap thickness (FCT ...

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    7. Feature Of The Week 8/4/13: MGH OCT Registry Reports on In Vivo OCT Studies of Plaque Erosion and Calcified Nodule In Acute Coronary Syndrome

      Feature Of The Week 8/4/13: MGH OCT Registry Reports on In Vivo OCT Studies of Plaque Erosion and Calcified Nodule In Acute Coronary Syndrome

      Pathology studies reported that three most common causes of acute coronary syndrome (ACS) or sudden cardiac death are plaque rupture, plaque erosion and calcified nodules. The morphological and clinical characteristics of the underlying pathology of ACS, especially plaque erosion and calcified nodule, have never been well studied in vivo. Using optical coherence tomography, we found that plaque erosions are the substrate for ACS in 31% of patients and calcified nodules in 8% of patients, which are consistent with pathological findings. Erosions are more likely to cause non-ST-segment elevation ACS than ST-segment elevation myocardial infarction. Compared to plaque rupture, plaque erosion ...

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    8. Correlation Between Degree of Neointimal Hyperplasia and Incidence and Characteristics of Neoatherosclerosis as Assessed by Optical Coherence Tomography

      Correlation Between Degree of Neointimal Hyperplasia and Incidence and Characteristics of Neoatherosclerosis as Assessed by Optical Coherence Tomography
      ...irst Department of Medicine, Nara Medical University, Nara, Japan , * Seung-Jung Park, MD, PhD Affiliations + Asan Medical Center, Seoul, Republic of Korea , * Stephen Lee, MD, PhD Affiliations + Department of Medicine, ...
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    9. The glaucoma detection capability of spectral-domain OCT and GDx-VCC deviation maps in early glaucoma patients with localized visual field defects

      The glaucoma detection capability of spectral-domain OCT and GDx-VCC deviation maps in early glaucoma patients with localized visual field defects
      ...ts with localized visual field defects Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, 388-1 Pungnap-2-dong, Songpa-gu, Seoul, Korea, 138-736 Gyeonggi Provincial Medical Center...
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    10. In Vivo Diagnosis of Plaque Erosion and Calcified Nodule in Patients with Acute Coronary Syndrome by Intravascular Optical Coherence Tomography

      In Vivo Diagnosis of Plaque Erosion and Calcified Nodule in Patients with Acute Coronary Syndrome by Intravascular Optical Coherence Tomography

      Objectives To characterize the morphological features of plaque erosion and calcified nodule in patients with acute coronary syndrome (ACS) by optical coherence tomography (OCT). Background Plaque erosion and calcified nodule have not been systematically investigated in vivo . Methods One hundred and twenty-six patients with ACS who had undergone pre-intervention OCT imaging were included. The culprit lesions were classified as plaque rupture (PR), erosion (OCT-erosion), calcified nodule (OCT-CN), or others using a new set of diagnostic criteria for OCT. Results The incidences of PR, OCT-erosion, and OCT-CN were 43.7%, 31.0%, and 7.9%, respectively. Patients with OCT-erosion were the ...

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    11. Detection of macular ganglion cell loss in preperimetric glaucoma patients with localized retinal nerve fiber defects by spectral-domain optical coherence tomography

      Detection of macular ganglion cell loss in preperimetric glaucoma patients with localized retinal nerve fiber defects by spectral-domain optical coherence tomography
      ... Korea 2. ^2 Department of Clinical Epidemiology and Biostatistics, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Republic of Korea ^* Correspondence: Michael S. Kook, MD, Department of Ophthalm...
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  2. About Asan Medical Center

    Asan Medical Center

    Asan Medical Center Korea’s largest tertiary referral hospital with 2,189 beds, was founded in 1989 by the late Chairman Chung_Ju-yung of Asan Foundation, with the philanthropic principles of meeting the growing demand for specialized treatments to the under privileged in society. Since then, this patient-oriented hospital has been caring more than 8,300 outpatients, 2,080 inpatients, and 180 emergency patients, while successfully performing 195 complex surgical operations on a daily basis. When AMC opens a 20-story new building in 2008, this hospital will be equipped with 3,000 beds and could offer upgraded health care services.