1. Armando Tellez

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    1. Mentioned In 11 Articles

    2. Optimizing flushing parameters in intracoronary optical coherence tomography: an in vivo swine study

      Optimizing flushing parameters in intracoronary optical coherence tomography: an in vivo swine study
      Intracoronary optical frequency domain imaging (OFDI), requires the displacement of blood for clear visualization of the artery wall. Radiographic contrast agents are highly effective at displacing blood however, may increase the risk of contrast-induced nephropathy. Flushing media viscosity, flow rate, and flush duration influence the efficiency of blood displacement necessary for obtaining diagnostic quality OFDI images. The aim of this work was to determine the optimal flushing parameters necessary to ...
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    3. Peri-strut low-intensity areas in optical coherence tomography correlate with peri-strut inflammation and neointimal proliferation: an in-vivo correlation study in the familial hypercholesterolemic coronary swine model of in-stent restenosis

      Peri-strut low-intensity areas in optical coherence tomography correlate with peri-strut inflammation and neointimal proliferation: an in-vivo correlation study in the familial hypercholesterolemic coronary swine model of in-stent restenosis
      Background: Peri-strut low-intensity area (PLI) is a common imaging finding during the evaluation of in-stent neointima using optical coherence tomography (OCT). We aimed to determine the biological significance of PLI by comparing in-vivo OCT images with the corresponding histological sections obtained from the familial hypercholesterolemic swine model of coronary stenosis. Methods: A total of 26 coronary vessels of nine familial hypercholesterolemic swine were injured with 30% balloon overstretch and then ...
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    4. Experimental evaluation of efficacy and healing response of everolimus-eluting stents in the familial hypercholesterolemic swine model: a comparative study of bioabsorbable versus durable polymer stent platforms

      Experimental evaluation of efficacy and healing response of everolimus-eluting stents in the familial hypercholesterolemic swine model: a comparative study of bioabsorbable versus durable polymer stent platforms
      Background: The utility of animal models for the prediction of drug-eluting stent (DES) efficacy in human clinical trials is still unclear. The familial hypercholesterolemic swine (FHS) model has been shown to induce a human-like neointimal response to bare metal stent (BMS) implantation. However, its utility to discriminate efficacy signals following DES implantation is unknown. In this study, we aimed to test the efficacy and healing response of several everolimus-eluting stent ...
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    5. Neointimal patterns obtained by optical coherence tomography correlate with specific histological components and neointimal proliferation in a swine model of restenosis

      Neointimal patterns obtained by optical coherence tomography correlate with specific histological components and neointimal proliferation in a swine model of restenosis
      Aims Although optical coherence tomography (OCT) is capable to detect microscopic peri-strut changes that seem to be related to neointimal inhibition and healing, its ability to characterize these components is still limited. In this study, we aimed to compare different OCT morphological characteristics with different in-stent neointimal tissue types analysed by histology. Methods A total of 69 stents (39 drug eluting and 30 bare metal stents) were implanted in coronary ...
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    6. OCT-Verified Peri-Strut Low-Intensity Areas and the Extent of Neointimal Formation After 3 Years Following Stent Implantation

      OCT-Verified Peri-Strut Low-Intensity Areas and the Extent of Neointimal Formation After 3 Years Following Stent Implantation
      Drug eluting stents (DES) have decreased substantially the neointimal formation after percutaneous coronary intervention (PCI). However, DES are not free from neointimal hyperplasia (NIH) and stent thrombosis, which are related to the delayed arterial healing following DES implantation. The recently introduced optical coherence tomography (OCT) enables a detailed investigation of vessel healing. The presence of peri-strut low intensity (PLI) has been described as a potential marker of abnormal neointimal healing ...
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    7. Correlation of Angiographic Late Loss With Neointimal Proliferation in Stents Evaluated by OCT and Histology in Porcine Coronary Arteries

      Correlation of Angiographic Late Loss With Neointimal Proliferation in Stents Evaluated by OCT and Histology in Porcine Coronary Arteries
      ...nditt, RCIS*, Krzysztof Milewski, MD, PhD*, Maxwell E. Afari, MD*, Yanping Cheng, MD*, Catalina Gallego, MD*, Armando Tellez, MD*, Gregg W. Stone, MD*, Greg L. Kaluza, MD, PhD*, Juan F. Granada, MD*,* * Skirball Center f...
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    8. 59 Optical Coherence Tomography Papers Presentations at Transcatheter Cardiovascular Therapeutics Conference (TCT 2009)

      59 Optical Coherence Tomography Papers Presentations at Transcatheter Cardiovascular Therapeutics Conference (TCT 2009)
      ...k coronary plaques at bifurcations with combined OCT and IVUS virtual histology Poster Abstract 15 Armando Tellez Long-term patterns of neointimal formation following bare metal stents in the LDL Receptor d...
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    9. Quantification of glucose diffusion in arterial tissues by using optical coherence tomography

      Several investigations suggest that the early stages of atherosclerosis are modulated by the selective permeability of the vascular tissue to pro-inflammatory molecules of different molecular weights. Up to date, a few experiments have been performed to study the permeability of arterial tissue to different molecules. This is primarily due to an absence of an experimental technique capable of depth-resolved, accurate and sensitive assessment of arterial permeability. In this paper, we ...
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  2. About Armando Tellez

    Armando Tellez is with the Skirball Center for Cardiovascular Research at the Cardiovascular Research Foundation and The Methodist Hospital at the Methodist DeBakey Heart & Vascular Center in Houston, Texas.