1. Aquyre Biosciences

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    1. Mentioned In 74 Articles

    2. Method and device for high resolution full field interference microscopy

      Method and device for high resolution full field interference microscopy
      The invention relates to an incoherent light full field interference microscopy device for the imaging of a volumetric scattering sample (106). The device comprises an interference device (100) between a reference wave (401), produced by reflection of an incident wave by a reflective surface (105) of a reference arm of the interference device, and an object wave (402) produced by backscattering of the incident wave by a slice of the ...
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    3. Full-field optical coherence tomography (FFOCT) for evaluation of endometrial cancer

      Full-field optical coherence tomography (FFOCT) for evaluation of endometrial cancer
      Full-field optical coherence tomography (FFOCT) quickly produces images that resemble conventional pathology images. We examined endometrium in an intra-operative like fashion (more than forty samples). FFOCT-imaged endometrium was recognizable to pathologists and compared favorably with microscopy of the same samples. Additional image enhancements and acquisition techniques were explored and may improve interpretation accuracy. Wider evaluation of images is ongoing, using more pathologist subjects. FFOCT may revolutionize pathology practice in the ...
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    4. A feasibility study of full-field optical coherence tomography for rapid evaluation of EUS-guided microbiopsy specimens

      A feasibility study of full-field optical coherence tomography for rapid evaluation of EUS-guided microbiopsy specimens
      Background Rapid on-site evaluation of cytologic specimens is a way of determining the adequacy of fine-needle aspiration (FNA). However, alternatives may be useful when the presence of a cytotechnologist and/or pathologist is not possible. Objective To evaluate the feasibility of using full-field optical coherence tomography (FFOCT) for FNA specimen quality assessment. Design FFOCT images were acquired on gastric, pancreatic, pelvic, and lymph-node formalin-fixed FNA specimens and were compared with ...
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    5. Full-Field Optical Coherence Tomography of Human Donor and Pathological Corneas

      Full-Field Optical Coherence Tomography of Human Donor and Pathological Corneas
      Purpose : To evaluate the performance of a full-field optical coherence tomography (FF-OCT) system in the study of human donor and pathological corneas and assess its suitability for use in eye banks. Methods : Our study was carried out using an FF-OCT system developed for non-invasive imaging of tissue structures in depth with ultrahigh resolution (1m in all directions). Images were acquired from eight stored human donor corneas (either edematous or after ...
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    6. En-face full-field optical coherence tomography for fast and efficient fingerprints acquisition

      En-face full-field optical coherence tomography for fast and efficient fingerprints acquisition
      Optical coherence tomography (OCT) has been recently proposed by a number of laboratories as a promising tool for fingerprints acquisitions and for fakes discrimination. Indeed OCT being a non-contact, non-destructive optical method that virtually sections the volume of biological tissues that strongly scatter light it appears obvious to use it for fingerprints. Nevertheless most of the OCT setups have to go through the long acquisition of a full 3D image ...
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    7. High resolution in-vivo imaging of skin with full field optical coherence tomography

      High resolution in-vivo imaging of skin with full field optical coherence tomography
      Full-field OCT (FFOCT) has the ability to provide en-face images with a very good axial sectioning as well as a very high transverse resolution (about 1 microns in all directions). Therefore it offers the possibility to visualize biological tissues with very high resolution both on the axial native view, and on vertical reconstructed sections. Here we investigated the potential dermatological applications of in-vivo skin imaging with FFOCT. A commercial FFOCT ...
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    8. Feature Of The Week: Feature Of The Week 1/26/14: ESPCI-ParisTech Investigates Full-Field Optical Coherence Tomograpy (FF-OCT) Shear Wave Elastography

      Feature Of The Week: Feature Of The Week 1/26/14: ESPCI-ParisTech Investigates Full-Field Optical Coherence Tomograpy (FF-OCT) Shear Wave Elastography
      Elasticity maps of tissue have proved to be particularly useful in providing complementary contrast to ultrasonic imaging, e.g., for cancer diagnosis at the millimeter scale. Optical coherence tomography (OCT) offers an endogenous contrast based on singly backscattered optical waves. Adding complementary contrast to OCT images by recording elasticity maps could also be valuable in improving OCT-based diagnosis at the microscopic scale. Static elastography has been successfully coupled with full-field ...
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    9. Full field optical coherence tomography of prostate biopsies: A step towards pre-histological diagnosis?

      Full field optical coherence tomography of prostate biopsies: A step towards pre-histological diagnosis?
      Objectives To evaluate the value of full field optical coherence tomography (FFOCT) for cancer detection on prostate biopsies Patients and methods Eight consecutive patients who underwent prostate biopsies for an elevated PSA or suspicious DRE findings were included in the study. For each patient, one to three biopsy cores were imaged with FFOCT immediately after sampling. Images obtained were analyzed by a pathologist blinded to the pathological results, and classified ...
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    10. 3D static elastography at the micrometer scale using Full Field OCT

      3D static elastography at the micrometer scale using Full Field OCT
      Full-Field OCT (FF-OCT) is able to image biological tissues in 3D with micrometer resolution. In this study we add elastographic contrast to the FF-OCT modality. By combining FF-OCT with elastography, we create a virtual palpation map at the micrometer scale. We present here a proof of concept on multi-layer phantoms and preliminary results on ex vivo biological samples such as porcine cornea, human breast tissues and rat heart. The 3D ...
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  2. About Aquyre Biosciences

    Aquyre Biosciences

    LLTech is a privately owned company founded in 2007. LLTech vision is to become the leader in real time, safe, non-destructive optical biopsies and cellular level tissue imaging for research and clinical applications (micro biopsies assessment, surgical margins…). Using the properties of white light and optics the Light-CT research scanner generates DICOM 3D high-resolution three-dimensional images of tissue microstructure, without introducing artifacts.