1. Aljoscha S. Neubauer

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    1. Mentioned In 12 Articles

    2. INTRAPAPILLARY PROLIFERATION IN OPTIC DISK PITS: Clinical Findings and Time-Related Changes

      INTRAPAPILLARY PROLIFERATION IN OPTIC DISK PITS: Clinical Findings and Time-Related Changes
      Purpose: To investigate the structural changes of intrapapillary proliferations associated with optic disk pits (ODPs) and optic disk pit maculopathy (ODP-M) using enhanced depth-spectral domain-optical coherence tomography (SD-EDI-OCT) and megahertz optical coherence tomography (MHz-OCT). Methods: Sixteen eyes of patients with ODPs were studied. Papillary and peripapillary areas were repeatedly examined with SD-EDI-OCT over time. To evaluate swept-source OCT, some of the patients additionally received MHz-OCT-imaging. Results: MHz-OCT or SD-EDI images ...
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    3. Combined 60° Wide-Field Choroidal Thickness Maps and High-Definition En Face Vasculature Visualization Using Swept-Source Megahertz OCT at 1050 nm

      Combined 60° Wide-Field Choroidal Thickness Maps and High-Definition En Face Vasculature Visualization Using Swept-Source Megahertz OCT at 1050 nm
      Purpose : To demonstrate ultrahigh-speed swept-source optical coherence tomography (SS-OCT) at 1.68 million A-scans/s for choroidal imaging in normal and diseased eyes over a 60 field of view. To investigate and correlate wide-field three-dimensional (3D) choroidal thickness (ChT) and vascular patterns using ChT maps and coregistered high-definition en face images extracted from a single densely sampled Megahertz-OCT (MHz-OCT) dataset. Methods : High-definition, 60 wide-field 3D datasets consisting of 2088 1024 ...
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    4. Feature Of The Week 7/6/2015: Ultra-Widefield Retinal MHz-OCT Imaging With up to 100 Degrees Viewing Angle

      Feature Of The Week 7/6/2015: Ultra-Widefield Retinal MHz-OCT Imaging With up to 100 Degrees Viewing Angle
      We evaluate strategies to maximize the field of view (FOV) of in vivo retinal OCT imaging of human eyes and analyze the problems caused by the increased scan angle. Three imaging modes are tested: Single volume imaging with 85 FOV as well as with 100 and stitching of five 60 images to a 100 mosaic (measured as usually from the nodal point). We employ a MHz-OCT system based on a ...
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    5. Ultra-widefield retinal MHz-OCT imaging with up to 100 degrees viewing angle

      Ultra-widefield retinal MHz-OCT imaging with up to 100 degrees viewing angle
      We evaluate strategies to maximize the field of view (FOV) of in vivo retinal OCT imaging of human eyes. Three imaging modes are tested: Single volume imaging with 85 FOV as well as with 100 and stitching of five 60 images to a 100 mosaic (measured from the nodal point). We employ a MHz-OCT system based on a 1060nm Fourier domain mode locked (FDML) laser with a depth scan rate ...
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    6. Megahertz ultra-wide-field swept-source retina optical coherence tomography compared to current existing imaging devices

      Megahertz ultra-wide-field swept-source retina optical coherence tomography compared to current existing imaging devices
      Background To investigate the image quality of wide-angle cross-sectional and reconstructed fundus images based on ultra-megahertz swept-source Fourier domain mode locking (FDML) OCT compared to current generation diagnostic devices. Methods A 1,050 nm swept-source FDML OCT system was constructed running at 1.68 MHz A-scan rate covering approximately 70 field of view. Twelve normal eyes were imaged with the device applying an isotropically dense sampling protocol (1,9001,900 ...
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    7. Multi-MHz retinal OCT

      Multi-MHz retinal OCT
      We analyze the benefits and problems of in vivo optical coherence tomography (OCT) imaging of the human retina at A-scan rates in excess of 1 MHz, using a 1050 nm Fourier-domain mode-locked (FDML) laser. Different scanning strategies enabled by MHz OCT line rates are investigated, and a simple multi-volume data processing approach is presented. In-vivo OCT of the human ocular fundus is performed at different axial scan rates of up ...
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    8. Feature Of The Week 6/23/13: Ludwig Maximilian University of Munich Investigates Benefits of Joint Aperture Detection in Ophthalmic MHz OCT

      Feature Of The Week 6/23/13: Ludwig Maximilian University of Munich Investigates Benefits of Joint Aperture Detection in Ophthalmic MHz OCT
      Joint-aperture optical coherence tomography (JA-OCT) is an angle-resolved OCT method, in which illumination from an active channel is simultaneously probed by several passive channels. JA-OCT increases the collection efficiency and effective sensitivity of the OCT system without increasing the power on the sample. Additionally, JA-OCT provides angular scattering information about the sample in a single acquisition, so the OCT imaging speed is not reduced. Thus, JA-OCT is especially suitable for ...
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    9. Optimizing visualization in enhanced depth imaging OCT in healthy subjects and patients with retinal pigment epithelial detachment

      Optimizing visualization in enhanced depth imaging OCT in healthy subjects and patients with retinal pigment epithelial detachment
      Background: This studys objective was to optimize the visualization of three different spectral-domain optical coherence tomography (SD-OCT) display modalities and evaluate enhanced depth imaging (EDI) by comparing the maximum depth of assessment in conventional versus inverted cross-sectional OCT images in healthy subjects and in patients with retinal pigment epithelial detachment (PED). Methods: Cross-sectional SD-OCT conventional and inverted images were obtained with the HRA2 (Heidelberg Retina Angiograph II, Heidelberg Engineering, Heidelberg ...
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    10. Feature Of The Week 9/4/11: Researchers at Ludwig-Maximilians University Continue to Blaze Trails Developing High Performance Swept Source OCT Technology and Its Application in Medical Imaging

      Feature Of The Week 9/4/11: Researchers at Ludwig-Maximilians University Continue to Blaze Trails Developing High Performance Swept Source OCT Technology and Its Application in Medical Imaging
      Researchers at Ludwig-Maximilians University continue to blaze trails in their work developing high performance swept source optical coherence tomography technology and the application of high speed frequency tuned sources in medical imaging. The Fourier-domain mode locked laser (FDML) together with tapped-delay line sweep-rate multipliers, light delivery and calibration optics, novel frame averaging and sampling techniques, wide FOV scanning technology, and high speed signal processing and visualization technology are impressive and ...
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    11. In vivo characterization of ischemic retina in diabetic retinopathy

      In vivo characterization of ischemic retina in diabetic retinopathy
      Objective: The aim of this article is to characterize pathomorphologic changes within particular layers of fluorescein angiographically 'ischemic' compared to 'nonischemic' retina in patients with diabetic retinopathy. Methods: Cross-sectional images of ischemic retinal areas were obtained using Heidelberg Spectralis optical coherence tomography (OCT). Presumed retinal ischemia was defined as focal hypofluorescence in early or early and late phase fluorescein angiography. Pathomorphologic changes on OCT were evaluated and the thickness of ...
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    12. Optimizing the Deswelling Process of Organ-Cultured Corneas

      Purpose: During deswelling of organ-cultured human corneas, endothelial cell loss occurs. Therefore, it is necessary to minimize the deswelling time and achieving an optimal central corneal thickness (CCT) of approximately 550 [mu]m at the same time. We investigated the minimal deswelling time necessary and analyzed endothelial cell loss. Methods: Fifty-eight human corneas were stored between 13 and 81 days in organ culture. CCT was measured by optical coherence tomography ...
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    13. Optical Coherence Tomography Fast versus Regular Macular Thickness Mapping in Diabetic Retinopathy.

      Ophthalmic Res. 2008 Apr 25;40(5):235-240 Authors: Ceklic L, Maár N, Neubauer AS Objective: The purpose of the study was to investigate if absolute values and reproducibility of thickness maps obtained from 2 optical coherence tomography (OCT) scanning protocols, regular high-resolution and fast low-density mode, differ in patients with diabetic macular edema. Methods: A total of 26 consecutive patients undergoing fluorescein angiography and Stratus OCT scanning for the ...
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    14. 1-12 of 12
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  2. About Aljoscha S. Neubauer

    Aljoscha S. Neubauer

    Aljoscha Neubauer is in the Department of Ophthalmology at Ludwig-Maximilians University.