1. Alexander V. Priezzhev

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    1. Mentioned In 15 Articles

    2. Recent progress in optical probing and manipulation of tissue: introduction

      Recent progress in optical probing and manipulation of tissue: introduction
      This feature issue of Biomedical Optics Express represents a cross-section of the most recent work in tissue optics, including exciting developments in tissue optical clearing, deep tissue imaging, optical elastography, nanophotonics in tissue, and therapeutic applications of light, amongst others. A collection of 33 papers provides a comprehensive overview of current research in tissue optics, much of it inspired and informed by the pioneering work of Prof. Valery Tuchin. The ...
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    3. Glucose sensing in flowing blood and Intralipid by laser pulse time-of-flight and optical coherence tomography techniques

      Glucose sensing in flowing blood and Intralipid by laser pulse time-of-flight and optical coherence tomography techniques
      In this paper, we compare the sensitivities of the two optical modalities, laser pulse time-of-flight (TOF) and optical coherence tomography (OCT), in regard to glucose sensing within the range of 0-1000 mg/dl in flowing blood and tissue-mimicking liquid (Intralipid). We show that TOF technique is about twice more sensitive than OCT, as well for blood as for Intralipid measurements. In case of TOF technique, glucose sensitivity in Intralipid is ...
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    4. Doppler OCT imaging of cytoplasm shuttle flow in Physarum polycephalum

      The Doppler optical coherence tomography technique was applied to image the oscillatory dynamics of protoplasm in the strands of the plasmodium of slime mould Physarum polycephalum. Radial contractions of the gel-like walls of the strands and the velocity distributions in the sol-like endoplasm streaming along the plasmodial strands are imaged. The motility inhibitor effect of carbon dioxide on the cytoplasm shuttle flow and strand-wall contraction is shown. The optical attenuation ...
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    5. Role of multiple scattering in formation of OCT skin images

      Optical coherence tomography (OCT) images of model human skin samples are obtained by using Monte Carlo simulations. The contributions of least and multiple scattering, diffusion and nondiffusion components and of separate scattering orders are studied by using a multilayer skin model based on experimental images. The model images are obtained by neglecting speckles or taking them into account. It is shown that least scattering forms the image of the upper ...
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    6. Contribution of various scattering orders to OCT images of skin

      Simulated OCT images of skin were obtained implementing Monte Carlo simulations. The multilayer skin model used in simulations was based on the experimental OCT images obtained at the wavelength of 910 nm. The following skin layers were considered in the model: stratum corneum, epidermis prickle layer, epidermis basal layer, dermis with upper plexus, dermis, and dermis with lower plexus. The images were obtained both with and without speckle accounting. The ...
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    7. Optical coherence tomography of paper: Monte Carlo simulation for multilayer mode

      In present work the capabilities of an optical coherence tomography (OCT) setup to visualize paper structure are analyzed by means of Monte Carlo-simulation of the OCT images. The OCT setup at 910 nm was considered. Efficiency of several different optical clearing agents (OCA) for increasing the quality of the obtained images was studied. A multilayer non-planar edged paper model was developed for the characterization of a paper sample and simple ...
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    8. Monte Carlo simulation of the optical coherence Doppler tomography signals from blood flows in light scattering media: problem of flow velocity profile reconstruction

      Optical Coherence Tomography (OCT) and Optical Coherence Doppler Tomography (OCDT) signals from one and two plain flows of a non-aggregating particulate suspension mimicking blood embedded into a stationary light scattering medium (2% Intralipid solution) with optical properties close to those of human skin were simulated implementing the Monte Carlo method. The role of multiple scattering in the OCT signals was analyzed. The maximal visualization depths for OCT imaging of different ...
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    9. Effect of multiple scattering on the accuracy of velocity profile reconstruction from the Monte-Carlo simulated OCDT signal in a model of biological tissues

      ...ocessor architecture was used for Monte-Carlo simulation. Optical Diagnostics and Sensing VI, Gerard L. Coté; Alexander V. Priezzhev, Editors, 609407 Using the Monte-Carlo method we simulated the Optical Coherence Dopple...
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    10. Analysis of distortions in the velocity profiles of suspension flows inside a light-scattering medium upon their reconstruction from the optical coherence Doppler tomograph signal

      Abstract. Model signals from one and two plane flows of a particle suspension are obtained for an optical coherence Doppler tomograph (OCDT) by the Monte-Carlo method. The optical properties of particles mimic the properties of non-aggregating erythrocytes. The flows are considered in a stationary scattering medium with optical properties close to those of the skin. It is shown that, as the flow position depth increases, the flow velocity determined from ...
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    11. Monte Carlo simulation of an optical coherence Doppler tomograph signal: the effect of the concentration of particles in a flow on the reconstructed velocity profile

      Abstract. Model signals of an optical coherence Doppler tomograph (OCDT) are obtained by the Monte Carlo method from a flow of a light-scattering suspension of lipid vesicles (intralipid) at concentrations from 0.7% to 1.5% with an a priori specified parabolic velocity profile. The velocity profile parameters reconstructed from the OCDT signal and scattering orders of the photons contributing to the signal are studied as functions of the suspension ...
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  2. About Alexander V. Priezzhev

    Alexander V. Priezzhev

    Alexander V. Priezzhev graduated from Physics Department of Lomonosov Moscow State University (MSU) in 1971 and earned his PhD degree in physics and mathematics from MSU in 1975. His current position is professor and head of biomedical photonics laboratory at Physics Department of MSU. He is also adjunct professor of School of Biomedical Engineering, Science and Health Systems at Drexel University, USA. Coauthor of more than 250 peer-review articles, invited talks and conference proceedings papers, several books and book chapters related to laser physics, biomedical optics and laser applications in biology and medicine.