1. Akitaka Tsujikawa

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    1. Mentioned In 52 Articles

    2. NONPERFUSION AREA QUANTIFICATION IN BRANCH RETINAL VEIN OCCLUSION: A WIDEFIELD OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY STUDY

      NONPERFUSION AREA QUANTIFICATION IN BRANCH RETINAL VEIN OCCLUSION: A WIDEFIELD OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY STUDY
      PURPOSE: To precisely quantify retinal nonperfusion areas (NPAs) in branch retinal vein occlusion (BRVO) using widefield optical coherence tomography angiography (OCTA), and examine their association with neovascular complications. METHODS: We enrolled 26 patients with treatment-nave BRVO and prospectively examined them for 12 months. After three monthly ranibizumab injections to treat macular edema, each patient underwent ultra-wide field (UWF) fluorescein angiography (FA) and OCTA. UWF FA was additionally performed at Month ...
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    3. Analysis of Retinal Nerve Fibre Thickening in Progressive and Non-progressive Non-arteritic Anterior Ischaemic Optic Neuropathy Using Optical Coherence Tomography

      Analysis of Retinal Nerve Fibre Thickening in Progressive and Non-progressive Non-arteritic Anterior Ischaemic Optic Neuropathy Using Optical Coherence Tomography
      The study aims to investigate the longitudinal changes in the circumpapillary retinal nerve fibre layer thickness (cpRNFLT) in progressive and non-progressive non-arteritic anterior ischaemic optic neuropathy (NAION). This retrospective observational case series study analysed 17 eyes with NAION. Patients sustaining any additional visual loss (additional decrease in visual acuity (VA) 0.2 logMAR) within two months after initial onset of symptoms were classified as having progressive NAION. Of the 17 ...
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    4. Effect of image averaging on optical coherence tomography angiography data in eyes with branch retinal vein occlusion

      Effect of image averaging on optical coherence tomography angiography data in eyes with branch retinal vein occlusion
      Purpose To investigate the effect of image averaging on qualitative and quantitative assessments of optical coherence tomography angiography (OCTA) images from eyes of patients with branch retinal vein occlusion (BRVO). Methods Macular OCTA images of 33 eyes of 33 patients with BRVO were obtained using the HS100 HR-SD-OCT system (Canon, Inc.). For each eye, five OCTA cube scans were obtained with a 33 mm scan protocol, and the data were ...
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    5. Enhanced Visualization of Retinal Microvasculature in Optical Coherence Tomography Angiography Imaging via Deep Learning

      Enhanced Visualization of Retinal Microvasculature in Optical Coherence Tomography Angiography Imaging via Deep Learning
      Background: To investigate the effects of deep learning denoising on quantitative vascular measurements and the quality of optical coherence tomography angiography (OCTA) images. Methods: U-Net-based deep learning denoising with an averaged OCTA data set as teacher data was used in this study. One hundred and thirteen patients with various retinal diseases were examined. An OCT HS-100 (Canon inc., Tokyo, Japan) performed a 3 3 mm 2 superficial capillary plexus layer ...
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    6. Usefulness of Denoising Process to Depict Myopic Choroidal Neovascularisation Using a Single Optical Coherence Tomography Angiography Image

      Usefulness of Denoising Process to Depict Myopic Choroidal Neovascularisation Using a Single Optical Coherence Tomography Angiography Image
      Quality of single optical coherence tomography angiography (OCTA) images of myopic choroidal neovascularisation (mCNV) is poorer than in averaged images, although obtaining averaged images takes much time. This study evaluated the clinical usefulness of novel denoising process for depicting mCNV. This study included 20 eyes of 20 patients with mCNV. Ten en face images taken in a 33mm macular cube were obtained from outer-retina-to-choriocapillaris layer. Three image types were prepared ...
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    7. Angiographic Risk Features of Branch Retinal Vein Occlusion Onset as Determined by Optical Coherence Tomography Angiography

      Angiographic Risk Features of Branch Retinal Vein Occlusion Onset as Determined by Optical Coherence Tomography Angiography
      Purpose : Examine associations between the vasculature at arteriovenous (AV) crossings and the onset of branch retinal vein occlusion (BRVO). Methods : We included 78 patients with major BRVO, 35 patients with macular BRVO, and 110 controls without BRVO and determined the vessel positions at AV crossings, where the first- or second-order branches of the retinal veins associate, using a viewing angle of 12 12 mm 2 in optical coherence tomography angiography ...
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    8. Disproportion of lamellar capillary non-perfusion in proliferative diabetic retinopathy on optical coherence tomography angiography

      Disproportion of lamellar capillary non-perfusion in proliferative diabetic retinopathy on optical coherence tomography angiography
      Purpose To characterise the non-perfused areas (NPAs) in the superficial and deep capillary layers (sNPAs and dNPAs, respectively) in the posterior pole in proliferative diabetic retinopathy (PDR) on wide-field optical coherence tomography angiography (OCTA) images. Methods We retrospectively reviewed 104 eyes of 70 patients with PDR from whom wide-field swept source OCTA images were acquired. sNPAs and dNPAs were manually measured in each quadrant of the inner (13mm diameter), intermediate ...
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    9. Anterior Segment Optical Coherence Tomography Angiography Imaging of Conjunctiva and Intrasclera in Treated Primary Open-Angle Glaucoma

      Anterior Segment Optical Coherence Tomography Angiography Imaging of Conjunctiva and Intrasclera in Treated Primary Open-Angle Glaucoma
      Purpose To investigate conjunctival and intrascleral vasculature in glaucoma eyes using anterior segment (AS)-optical coherence tomography angiography (OCTA) and assess the factors contributing to the vessel density in AS-OCTA images. Design Prospective, cross-sectional study. Methods Thirty-four patients with primary open-angle glaucoma and 20 healthy subjects were included. A swept-source OCT system was used to obtain AS-OCTA images of the corneal limbus at the nasal and temporal quadrants. Vessel densities ...
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    10. Characteristics of Diabetic Capillary Nonperfusion in Macular and Extramacular White Spots on Optical Coherence Tomography Angiography

      Characteristics of Diabetic Capillary Nonperfusion in Macular and Extramacular White Spots on Optical Coherence Tomography Angiography
      Purpose : To compare the characteristics of macular and extramacular white spots on wide-field swept-source optical coherence tomography angiography (SS-OCTA) and optical coherence tomography (OCT) images in diabetic retinopathy (DR). Methods : We retrospectively reviewed 107 eyes of 64 patients with DR, of whom nominal 12 12 mm SS-OCTA images centered on the optic disc and ultrawide field photographs were acquired. White spots on fundus photographs corresponded to hyperreflective lesions in the ...
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    11. A novel strategy for quantification of panoramic en face optical coherence tomography angiography scan field

      A novel strategy for quantification of panoramic en face optical coherence tomography angiography scan field
      Purpose To compare the retinal area measured on a panoramic en face optical coherence tomography angiography (OCTA) image with that on an ultra-widefield fluorescein angiography (UWF FA) image. Methods Sixteen eyes (11 with branch retinal vein occlusion, 2 with central retinal vein occlusion, 1 with branch retinal artery occlusion, and 2 with hypertensive retinopathy) were included in this study. A panoramic en face OCTA image was created from five single ...
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    12. Concentric Choriocapillaris Flow Deficits in Retinitis Pigmentosa Detected Using Wide-Angle Swept-Source Optical Coherence Tomography Angiography

      Concentric Choriocapillaris Flow Deficits in Retinitis Pigmentosa Detected Using Wide-Angle Swept-Source Optical Coherence Tomography Angiography
      Purpose : We investigate whether choriocapillaris deficits can be visualized in patients with retinitis pigmentosa (RP) using wide-angle swept-source optical coherence tomography angiography (OCTA), and whether angiography or structure en face images depict a wider area of residual choriocapillaris. Methods : This cross-sectional study included 43 eyes of 43 consecutive patients with RP with a visual acuity 0.1, and 12 healthy eyes of 12 volunteers. Using an OCTA device (PLEX Eite ...
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    13. One-Year Outcome Predictors of Strabismus Surgery from Anterior Segment Optical Coherence Tomography with Multiple B-Scan Averaging

      One-Year Outcome Predictors of Strabismus Surgery from Anterior Segment Optical Coherence Tomography with Multiple B-Scan Averaging
      Strabismologists are eager to identify preoperative or intraoperative strabismus surgery outcome predictors because of the variable effects in each patient. Conjunctival closure position recession after rectus muscle recession is effective for correcting large angle strabismus. The elasticity of the conjunctiva and Tenons capsule is important for strabismus surgery management. In this longitudinal study, we evaluated the prognosis of conjunctiva and Tenons capsule thickness (CTT) near the limbus 1 year after ...
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    14. Diabetic Nonperfused Areas in Macular and Extramacular Regions on Wide-Field Optical Coherence Tomography Angiography

      Diabetic Nonperfused Areas in Macular and Extramacular Regions on Wide-Field Optical Coherence Tomography Angiography
      Purpose : To investigate the nonperfused areas (NPAs) in each subfield segmented by large arterioles on wide-field swept-source optical coherence tomography angiography (SS-OCTA) images in diabetic retinopathy. Methods : We retrospectively reviewed 101 consecutive eyes of 67 patients with severe nonproliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy (PDR), for whom 12 12-mm SS-OCTA images centered on the optic disc were acquired. Both eyes were included in 34 patients. NPAs in the ...
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    15. Segmentation of the Four-Layered Retinal Vasculature Using High-Resolution Optical Coherence Tomography Angiography Reveals the Microcirculation Unit

      Segmentation of the Four-Layered Retinal Vasculature Using High-Resolution Optical Coherence Tomography Angiography Reveals the Microcirculation Unit
      Purpose : To differentiate the four layers of the retinal vessel network in the human macula and examine their morphologic features using high-resolution optical coherence tomography angiography (HR-OCTA). Methods : Macular areas measuring 464 464 pixels of 10 right eyes of 10 healthy subjects without ocular disease were scanned 10 times using a HR-OCTA device. Averaged OCTA images were created. Based on clear decorrelation signals, four vascular slabs were segmented, comprising one ...
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    16. Anterior Segment Optical Coherence Tomography Angiography in a Patient With Persistent Pupillary Membrane

      Anterior Segment Optical Coherence Tomography Angiography in a Patient With Persistent Pupillary Membrane
      The image depicts a 60-year-old woman with bilateral cataracts and no history of amblyopia, strabismus, or systemic diseases. Color slitlamp photography of the left eye ( Figure , A) showed a persistent pupillary membrane, with multiple iris strands extending from collarette to collarette and adhering to the anterior lens surface. Anterior segment optical coherence tomography angiography ( Figure , B) showed vessels originating from the lesser arterial circle of the iris and anastomosing with ...
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  2. About Akitaka Tsujikawa

    Akitaka Tsujikawa, MD, is with the Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan