1. Adrian Mariampillai

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    1. Mentioned In 29 Articles

    2. Histogram flow mapping with optical coherence tomography for in vivo skin angiography of hereditary hemorrhagic telangiectasia

      Histogram flow mapping with optical coherence tomography for in vivo skin angiography of hereditary hemorrhagic telangiectasia
      ...nto M5S 3G4, Canada Ryerson University, Biophotonics and Bioengineering Laboratory, Toronto M5B 2K3, Canada Adrian Mariampillai, Barry Vuong, Timothy W. H. Luk Ryerson University, Biophotonics and Bioengineering Labo...
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    3. Method And System For Determining Whether Arterial Tissue Comprises Atherosclerotic Plaque

      Method And System For Determining Whether Arterial Tissue Comprises Atherosclerotic Plaque
      Provided herein are methods and systems to determine at least one mechanical property of a tissue sample and, based upon the determined at least one mechanical property, whether the tissue sample comprises atherosclerotic plaque. The method comprises generating a shear wave in an arterial tissue sample by applying an acoustic impulse thereto; measuring propagation of the shear wave via an optical coherence elastography apparatus; determining at least one mechanical property ...
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    4. Optical coherence tomography detection of shear wave propagation in inhomogeneous tissue equivalent phantoms and ex-vivo carotid artery samples

      Optical coherence tomography detection of shear wave propagation in inhomogeneous tissue equivalent phantoms and ex-vivo carotid artery samples
      In this work, we explored the potential of measuring shear wave propagation using optical coherence elastography (OCE) in an inhomogeneous phantom and carotid artery samples based on a swept-source optical coherence tomography (OCT) system. Shear waves were generated using a piezoelectric transducer transmitting sine-wave bursts of 400 s duration, applying acoustic radiation force (ARF) to inhomogeneous phantoms and carotid artery samples, synchronized with a swept-source OCT (SS-OCT) imaging system. The ...
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    5. Review of speckle and phase variance optical coherence tomography to visualize microvascular networks

      Review of speckle and phase variance optical coherence tomography to visualize microvascular networks
      High-resolution mapping of microvasculature has been applied to diverse body systems, including the retinal and choroidal vasculature, cardiac vasculature, the central nervous system, and various tumor models. Many imaging techniques have been developed to address specific research questions, and each has its own merits and drawbacks. Understanding, optimization, and proper implementation of these imaging techniques can significantly improve the data obtained along the spectrum of unique research projects to obtain ...
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    6. Computing Device And Method For Detecting Cell Death In A Biological Sample

      Computing Device And Method For Detecting Cell Death In A Biological Sample
      A computing device system and method for detecting cell death in a biological sample is provided. A plurality of optical coherence tomography (OCT) data sets are received, each representative of OCT backscatter data collected from the biological sample and comprising respective signal fluctuation as a function of time at different respective times over a given time period. Respective indications of respective signal decorrelation rates are determined for each of the ...
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    7. In vivo feasibility of endovascular Doppler optical coherence tomography

      In vivo feasibility of endovascular Doppler optical coherence tomography
      Feasibility of detecting intravascular flow using a catheter based endovascular optical coherence tomography (OCT) system is demonstrated in a porcine carotid model in vivo. The effects of A-line density, radial distance, signal-to-noise ratio, non-uniform rotational distortion (NURD), phase stability of the swept wavelength laser and interferometer system on Doppler shift detection limit were investigated in stationary and flow phantoms. Techniques for NURD induced phase shift artifact removal were developed by ...
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    8. Real-time speckle variance swept-source optical coherence tomography using a graphics processing unit

      Real-time speckle variance swept-source optical coherence tomography using a graphics processing unit
      Abstract: Advances in swept source laser technology continues to increase the imaging speed of swept-source optical coherence tomography (SS-OCT) systems. These fast imaging speeds are ideal for microvascular detection schemes, such as speckle variance (SV), where interframe motion can cause severe imaging artifacts and loss of vascular contrast. However, full utilization of the laser scan speed has been hindered by the computationally intensive signal processing required by SS-OCT and SV ...
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    9. Quantification of glucose levels in flowing blood using M-mode swept source optical coherence tomography

      Quantification of glucose levels in flowing blood using M-mode swept source optical coherence tomography
      Abstract  The increase of glucose levels in blood changes the viscosity of flowing fluids and shape of the erythrocytes. Both of these can affect the details of light scattering as can be quantified via decorrelation times measured by optical coherence tomography (OCT). The relative contributions of these competing effects have been studied by examining the motion dynamics of deformable asymmetrical (red blood cells, RBCs with ∼7 μm diameter and ∼2 ...
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    10. Neurosurgical hand-held optical coherence tomography (OCT) forward-viewing probe

      Neurosurgical hand-held optical coherence tomography (OCT) forward-viewing probe
      A prototype neurosurgical hand-held optical coherence tomography (OCT) imaging probe has been developed to provide micron resolution cross-sectional images of subsurface tissue during open surgery. This new ergonomic hand-held probe has been designed based on our group's previous work on electrostatically driven optical fibers. It has been packaged into a catheter probe in the familiar form factor of the clinically accepted Bayonet shaped neurosurgical non-imaging Doppler ultrasound probes. The ...
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    11. Endovascular optical coherence tomography intensity kurtosis: visualization of vasa vasorum in porcine carotid artery

      Endovascular optical coherence tomography intensity kurtosis: visualization of vasa vasorum in porcine carotid artery
      lication of speckle variance optical coherence tomography (OCT) to endovascular imaging faces difficulty of extensive motion artifacts inherently associated with arterial pulsations in addition to other physiological movements. In this study, we employed a technique involving a fourth order statistical method, kurtosis, operating on the endovascular OCT intensity images to visualize the vasa vasorum of carotid artery in vivo and identify its flow dynamic in a porcine model. The intensity ...
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    12. 1-15 of 29 1 2 »
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  2. About Adrian Mariampillai

    Adrian Mariampillai  is a graduate student in Department of Medical Biophysics at the University of Toronto working wiht Professor Alex Vitkin.