1. Adnan Tufail

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    1. Mentioned In 44 Articles

    2. Optical Coherence Tomography in Pediatric Ophthalmology: Current Roles and Future Directions

      Optical Coherence Tomography in Pediatric Ophthalmology: Current Roles and Future Directions
      The application of existing optical coherence tomography (OCT) technology to the pediatric population is limited in both the design specification of the device and its hardware. However, the potential of OCT in the pediatric population has not been fully realized. The authors review the literature, highlighting the currently available spectral-domain OCT technology and summarizing the reported normal pediatric OCT parameters for retinal nerve fiber layer and macular thickness. They also ...
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    3. Evaluation of retinal pigment epithelium-Bruch's membrane complex thickness in dry age-related macular degeneration using optical coherence tomography

      Evaluation of retinal pigment epithelium-Bruch's membrane complex thickness in dry age-related macular degeneration using optical coherence tomography
      Aim To compare retinal pigment epitheliumBruch's membrane (RPEBM) complex thickness in patients with early and intermediate dry age-related macular degeneration (AMD) and age-matched controls using spectral domain optical coherence tomography (SD-OCT). Methods In this retrospective, cross-sectional study, 25 patients with dry AMD and 25 controls were recruited. SD-OCT scans were manually segmented by two independent investigators. Thickness values were calculated for the nine Early Treatment Diabetic Retinopathy Study (ETDRS ...
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    4. Choroidal assessment in idiopathic panuveitis using optical coherence tomography

      Choroidal assessment in idiopathic panuveitis using optical coherence tomography
      Background Idiopathic panuveitis is a diagnosis of exclusion that lacks distinguishing features on fluorescein and indocyanine green angiography. Choroidal hypoperfusion or ischaemia has been implicated in panuveitis of different aetiologies. In this study, we use enhanced depth imaging optical coherence tomography (OCT) to examine the choroid and its vasculature in patients with this disease. Methods In this retrospective, cross-sectional study, OCT-derived measurements of retinal and choroidal thickness were obtained after ...
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    5. Repeatability and Reproducibility of Choroidal Vessel Layer Measurements in Diabetic Retinopathy using Enhanced Depth Optical Coherence Tomography

      Repeatability and Reproducibility of Choroidal Vessel Layer Measurements in Diabetic Retinopathy using Enhanced Depth Optical Coherence Tomography
      Purpose: To describe novel segmentation protocols for choroidal layers - Sattler's medium and Haller's large vessel layers, using enhanced depth imaging optical coherence tomography (EDI-OCT), and to examine the repeatability and reproducibility of these measurements in eyes with diabetic retinopathy. Methods: Fifty-one patients with Type 2 diabetes mellitus were imaged using custom EDI scanning protocols. Detailed segmentation was performed to quantify the retina, choroid, Haller's large, and Sattler ...
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    6. Evaluation of Age-related Macular Degeneration With Optical Coherence Tomography

      Evaluation of Age-related Macular Degeneration With Optical Coherence Tomography
      Abstract: Age-related macular degeneration (AMD) is the leading cause of severe visual loss in people aged 50 years or older in the developed world. In recent years, major advances have been made in the treatment of AMD, with the introduction of anti-angiogenic agents, offering the first hope of significant visual recovery for patients with neovascular AMD. In line with these advances, a new imaging modalityoptical coherence tomography (OCT)has emerged ...
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    7. Assessment of Differential Pharmacodynamic Effects using Optical Coherence Tomography in Neovascular Age-Related Macular Degeneration

      Assessment of Differential Pharmacodynamic Effects using Optical Coherence Tomography in Neovascular Age-Related Macular Degeneration
      Purpose: To assess the differential pharmacodynamic effects of bevacizumab (Avastin), pegaptanib (Macugen), and verteporfin photodynamic therapy (PDT), using novel OCT parameters, in a recently completed phase III/IV clinical trial. Methods: Data from 122 patients participating in the Avastin (Bevacizumab) for Choroidal neovascularization (ABC) trial, were evaluated. Stratus OCT images were analyzed using custom software - changes in volume of the neurosensory retina, subretinal fluid (SRF), pigment epithelium detachment (PED), and ...
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    8. Topographic variation and interocular symmetry of macular choroidal thickness using enhanced depth imaging optical coherence tomography

      Topographic variation and interocular symmetry of macular choroidal thickness using enhanced depth imaging optical coherence tomography
      ...oherence tomography 1. Fred K Chen^1,^2, 2. Jonathan Yeoh^3, 3. Waheeda Rahman^4, 4. Praveen J Patel^4,^5, 5. Adnan Tufail^4,^5 and 6. Lyndon Da Cruz^4,^5 1. ^1. Centre for Ophthalmology and Visual Science (incorporating...
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    9. Repeatability of manual subfoveal choroidal thickness measurements in healthy subjects using the technique of enhanced depth imaging optical coherence tomography

      Repeatability of manual subfoveal choroidal thickness measurements in healthy subjects using the technique of enhanced depth imaging optical coherence tomography
      Purpose- The aim of this study was to investigate the repeatability of manual measurements of choroidal thickness in normal subjects imaged on spectral domain optical coherence tomography (OCT) using the enhanced depth imaging (EDI) technique. Methods- Fifty consecutive, healthy, young, adult volunteers with no known eye disease were enrolled prospectively. Two good quality, horizontal and vertical line scans through the fovea were obtained for each eye. Using the manual callipers ...
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    10. Intrasession repeatability of optical coherence tomography measures in active neovascular age-related macular degeneration

      Objectives: To determine the repeatability of Stratus optical coherence tomography fast macular thickness map analysis in patients with active neovascular age-related macular degeneration (nAMD).Methods: Consecutive pairs of scans from 112 eyes of 112 consecutive patients with active nAMD were analyzed. The Bland[ndash]Altman coefficient of repeatability (CR) was calculated for each retinal thickness or volume measure.Results: The CR for the central 1 mm macular subfield was 59 ...
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    11. Intersession repeatability of optical coherence tomography measures of retinal thickness in early age-related macular degeneration

      Purpose: To determine the intersession repeatability of Stratus optical coherence tomography (OCT) measures of retinal thickness in patients with age-related macular degeneration (AMD).Methods: Measurement of retinal thickness was performed over four sessions over 12 weeks using a standardized OCT protocol with the fast macular thickness map in 67 non-treated eyes of 67 patients with AMD enrolled in a clinical trial. The intrapatient standard deviation (Sw) and 95% coefficient of ...
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    12. Segmentation Error in Stratus Optical Coherence Tomography for Neovascular Age-Related Macular Degeneration

      This study reports the rate of segmentation error, the effect of these errors on the accuracy of retinal thickness measurements and the impact of repeat scanning on segmentation error in Stratus OCT scans of patients undergoing anti-VEGF therapy for neovascular AMD.
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    13. Repeatability of Stratus Optical Coherence Tomography Measures in Neovascular Age-Related Macular Degeneration

      purpose. To determine the repeatability of Stratus optical coherence tomography (OCT) measures of retinal thickness and volume in patients with neovascular age-related macular degeneration (nAMD) method. Fifty-one eyes of 51 consecutive patients with nAMD underwent an OCT imaging session in which two fast macular thickness map (FMTM) protocol scans sets were acquired by a single experienced operator certified for clinical trials work. Coefficients of repeatability for each of nine Early ...
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    14. 31-44 of 44 « 1 2 3
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  2. About Adnan Tufail

    Adnan Tufail, MD, is a consultant at Moorfields Eye Hospital, London, United Kingdom.