1. Adam R. Boretsky

    0 Comments Leave a Comment

    1-11 of 11
    1. Mentioned In 11 Articles

    2. Image quality metrics for optical coherence angiography

      Image quality metrics for optical coherence angiography
      We characterized image quality in optical coherence angiography (OCA)en faceplanes of mouse cortical capillary network in terms of signal-to-noise ratio (SNR) and Weber contrast (Wc) through a novel mask-based segmentation method. The method was used to compare two adjacent B-scan processing algorithms, (1) average absolute difference (AAD) and (2) standard deviation (SD), while varying the number of lateral cross-sections acquired (also known as the gate length, N). AAD and ...
      Read Full Article
    3. Nicotine Accelerates Diabetes-Induced Retinal Changes

      Nicotine Accelerates Diabetes-Induced Retinal Changes
      Purpose : To investigate the effects of nicotine on retinal alterations in early-stage diabetes in an established rodent model. Materials and Methods : SpragueDawley rats were examined using a combination of confocal scanning laser ophthalmoscopy and spectral domain optical coherence tomography to determine changes in retinal structure in response to nicotine exposure, diabetes and the combined effects of nicotine and diabetes . Diabetes was induced by a single injection of 65mg/kg streptozotocin ...
      Read Full Article
    4. Automated retinal layer segmentation and characterization

      Automated retinal layer segmentation and characterization
      Spectral Domain Optical Coherence Tomography (SD-OCT) is a valuable diagnostic tool in both clinical and research settings. The depth-resolved intensity profiles generated by light backscattered from discrete layers of the retina provide a non-invasive method of investigating progressive diseases and injury within the eye. This study demonstrates the application of steerable convolution filters capable of automatically separating gradient orientations to identify edges and delineate tissue boundaries. The edge maps were ...
      Read Full Article
    5. High-Resolution Multimodal Imaging of Multiple Evanescent White Dot Syndrome

      High-Resolution Multimodal Imaging of Multiple Evanescent White Dot Syndrome
      The integrity of macular morphology was examined in a patient with multiple evanescent white dot syndrome (MEWDS) diagnosed through clinical and investigational adaptive optics (AO) retinal imaging techniques. Imaging was performed during the acute and recovery phases to examine changes in retinal morphology, revealing characteristic small multifocal white dots in the perifoveal region and a granular appearance in the fovea. Fluorescein angiography revealed early and intermediate hyperfluorescence, and regions of ...
      Read Full Article
    6. Retinal optical coherence tomography image enhancement via shrinkage denoising using double-density dual-tree complex wavelet transform

      Retinal optical coherence tomography image enhancement via shrinkage denoising using double-density dual-tree complex wavelet transform
      Image enhancement of retinal structures, in optical coherence tomography (OCT) scans through denoising, has the potential to aid in the diagnosis of several eye diseases. In this paper, a locally adaptive denoising algorithm using double-density dual-tree complex wavelet transform, a combination of the double-density wavelet transform and the dual-tree complex wavelet transform, is applied to reduce speckle noise in OCT images of the retina. The algorithm overcomes the limitations of ...
      Read Full Article
    7. An Edge Detection Approach for Mapping of the Human Cone Photoreceptor Mosaic using Adaptive Optics Scanning Laser Ophthalmoscope

      An Edge Detection Approach for Mapping of the Human Cone Photoreceptor Mosaic using Adaptive Optics Scanning Laser Ophthalmoscope
      ...n, Adam R. Boretsky, Frederik J. van Kuijk, and Massoud Motamedi »View Author Affiliations Shahab Chitchian, Adam R. Boretsky, Massoud Motamedi University of Texas Medical Branch, United States Frederik J. van Kuijk Uni...
      Read Full Article
    8. Laser injury and in vivo multimodal imaging using a mouse model

      Laser injury and in vivo multimodal imaging using a mouse model
      Balb/c wild type mice were used to perform in vivo experiments of laser-induced thermal damage to the retina. A Heidelberg Spectralis HRA confocal scanning laser ophthalmoscope with a spectral domain optical coherence tomographer was used to obtain fundus and cross-sectional images of laser induced injury in the retina. Sub-threshold, threshold, and supra-threshold lesions were observed using optical coherence tomography (OCT), infrared reflectance, red-free reflectance, fluorescence angiography, and autofluorescence imaging ...
      Read Full Article
    9. Dermal scatter reduction in human skin: A method using controlled application of glycerol

      Previous studies in a hairless Guinea pig model showed that transdermal application of glycerol effected a temporary reduction in dermal scatter of light. This study focuses on the application of this protocol on human patients.After stratum corneal removal, glycerol was applied to human subjects using a low pressure transdermal application device. Optical coherence tomography imaging showed increased intensity of radiation reaching deeper regions in the skin and photographs showed ...
      Read Full Article
    10. Specular reflection vs. backscattering for transdermal OCT-based glucose monitoring with an implantable sensor system

      The reliability of optical techniques for non-invasive monitoring of glucose can be significantly improved by the deployment of a subcutaneous implantable sensor that can closely track the changes in the local concentration of glucose in skin. We have developed a novel implantable sensor that can track glucose-induced changes in the optical turbidity of the implant. In this sensor, optical turbidity decreases significantly with increased glucose concentrations. We performed comparative measurements ...
      Read Full Article
    11. Affinity-Based Turbidity Sensor for Glucose Monitoring by Optical Coherence Tomography: Toward the Development of an Implantable Sensor

      We investigated the feasibility of constructing an implantable optical-based sensor for seminoninvasive continuous monitoring of analytes. In this novel sensor, analyte concentration-dependent changes induced in the degree of optical turbidity of the sensing element can be accurately monitored by optical coherence tomography (OCT), an interferometric technique. To demonstrate proof-of-concept, we engineered a sensor for monitoring glucose concentration that enabled us to quantitatively monitor the glucose-specific changes induced in bulk scattering ...
      Read Full Article
    12. 1-11 of 11
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About Adam R. Boretsky

    Adam R. Boretsky is at the University of Texas Medical Branch at Galveston.