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Academic Medical Center at the University of Amsterdam

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1. Mentioned In 168 Articles
2. Illuminating the trapeziometacarpal joint: Dawn for optical coherence tomography in osteoarthritis (Thesis)
  
  Explore UvA DARE Jun 15 2020 Student Theses
  
  Osteoarthritis (OA) is a debilitating degenerative joint disease affecting millions of patients worldwide and is characterized by loss of cartilage thickness and quality in affected joints. OA of the trapeziometacarpal (TMC) joint or thumb base joint especially gives rise to loss of hand function and disability. However, clinical imaging strategies have thus far been unable to accurately assess the thin cartilage layers lining small joints like the TMC joint. Moreover ...
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  Mentions: Academic Medical Center at the University of Amsterdam
3. Optical Coherence Tomography Intensity Correlates with Extracellular Matrix Components in the Airway Wall
  
  Explore Home (thoracic) May 5 2020 Pulmonology
  
  No abstract provided.
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  Mentions: Academic Medical Center at the University of Amsterdam University of Groningen Daniël M. de Bruin
4. Parametric imaging of attenuation by optical coherence tomography: review of models, methods, and clinical translation
  
  Explore SPIE Digital Library Apr 20 2020
  
  Significance: Optical coherence tomography (OCT) provides cross-sectional and volumetric images of backscattering from biological tissue that reveal the tissue morphology. The strength of the scattering, characterized by an attenuation coefficient, represents an alternative and complementary tissue optical property, which can be characterized by parametric imaging of the OCT attenuation coefficient. Over the last 15 years, a multitude of studies have been reported seeking to advance methods to determine the OCT ...
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  Mentions: David D. Sampson University of Western Australia Academic Medical Center at the University of Amsterdam
5. In vivo characterization of chick embryo mesoderm by optical coherence tomography assisted microindentation
  
  Explore bioRxiv.org Mar 17 2020 Cardiology , Developmental Biology
  
  Embryos are growing organisms with highly heterogeneous properties in space and time. Understanding the mechanical properties is a crucial prerequisite for the investigation of morphogenesis. During the last ten years, new techniques have been developed to evaluate the mechanical properties of biological tissues in vivo . To address this need, we employed a new instrument that, via the combination of micro-indentation with Optical Coherence Tomography (OCT), allows us to determine both ...
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  Mentions: Academic Medical Center at the University of Amsterdam VU University Amsterdam
6. En‐face optical coherence tomography for the detection of cancer in prostatectomy specimens: quantitative analysis in 20 patients
  
  Explore Wiley Online Library Feb 21 2020 Urology
  
  The increase histopathological evaluation of prostatectomy specimens rises the workload on pathologists. Automated histopathology systems, preferably directly on unstained specimens, would accelerate the pathology workflow. In this study, we investigate the potential of quantitative analysis of Optical Coherence Tomography (OCT) to separate benign from malignant prostate tissue automatically. Twenty fixated prostates were cut, from which 54 slices were scanned by OCT. Quantitative OCT metrics (attenuation coefficient, residue, goodness‐of‐fit ...
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  Mentions: Academic Medical Center at the University of Amsterdam Dirk J. Faber Ton G. van Leeuwen
7. Randomized Comparison Between Everolimus-Eluting Bioresorbable Scaffold and Metallic Stent Multimodality Imaging Through 3 Years
  
  Explore interventions.onlinejacc.org Jan 12 2020 Cardiology
  
  Objectives The aim of this study was to investigate the vascular responses and fates of the scaffold after bioresorbable vascular scaffold (BVS) implantation using multimodality imaging. Background Serial comprehensive image assessments after BVS implantation in the context of a randomized trial have not yet been reported. Methods In the ABSORB Japan trial, 400 patients were randomized to a BVS (n = 266) or a cobalt-chromium everolimus-eluting stent (n = 134). Through 3 ...
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  Mentions: Beth Israel Deaconess Medical Center Columbia University Stanford University
8. Advances in Optical Coherence Tomography and Confocal Laser Endomicroscopy in Pulmonary Diseases
  
  Explore Karger Publishers Oct 14 2019 Pulmonology
  
  Diagnosing and monitoring pulmonary diseases is highly dependent on imaging, physiological function tests and tissue sampling. Optical coherence tomography (OCT) and confocal laser endomicroscopy (CLE) are novel imaging techniques with near-microscopic resolution that can be easily and safely combined with conventional bronchoscopy. Disease-related pulmonary anatomical compartments can be visualized, real time, using these techniques. In obstructive lung diseases, airway wall layers and related structural remodelling can be identified and quantified ...
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  Mentions: Academic Medical Center at the University of Amsterdam
9. Computed Tomography–Mediated Registration of Trapeziometacarpal Articular Cartilage Using Intraarticular Optical Coherence Tomography and Cryomicrotome Imaging: A Cadaver Study
  
  Explore SAGE Journals Jul 16 2019
  
  Objective Accurate, high-resolution imaging of articular cartilage thickness is an important clinical challenge in patients with osteoarthritis, especially in small joints. In this study, computed tomography (CT) mediated catheter-based optical coherence tomography (OCT) was utilized to create a digital reconstruction of the articular surface of the trapeziometacarpal (TMC) joint and to assess cartilage thickness in comparison to cryomicrotome data. Design Using needle-based introduction of the OCT probe, the articular surface ...
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  Mentions: Academic Medical Center at the University of Amsterdam Ton G. van Leeuwen Daniël M. de Bruin
10. Simple and robust calibration procedure for k-linearization and dispersion compensation in optical coherence tomography
  
  Explore SPIE Digital Library May 23 2019
  
  In Fourier-domain optical coherence tomography (FD-OCT), proper signal sampling and dispersion compensation are essential steps to achieve optimal axial resolution. These calibration steps can be performed through numerical signal processing, but require calibration information about the system that may require lengthy and complex measurement protocols. We report a highly robust calibration procedure that can simultaneously determine correction vectors for nonlinear wavenumber sampling and dispersion compensation. The proposed method requires only ...
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  Mentions: Academic Medical Center at the University of Amsterdam Polytechnique Montreal Dirk J. Faber
11. Optical coherence tomography to detect acute esophageal radiation-induced damage in mice: a validation study
  
  Explore Wiley Online Library May 14 2019 Gastroenterology
  
  Radiation therapy for patients with non-small-cell lung cancer is hampered by acute radiation-induced toxicity in the esophagus. This study aims to validate that optical coherence tomography (OCT), a minimally invasive imaging technique with high resolution (~10 m), is able to visualize and monitor acute radiation-induced esophageal damage (ARIED) in mice. We compare our findings with histopathology as the gold standard. Irradiated mice receive a single dose of 40 Gy at ...
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  Mentions: Johannes F. de Boer Academic Medical Center at the University of Amsterdam VU University Amsterdam
12. Decreasing the Size of a Spectral Domain Optical Coherence Tomography System With Cascaded ...
  
  Explore IEEE Xplore Apr 18 2019 Ophthalmology
  
  This paper describes a proof-of-concept of a miniaturized spectral-domain optical coherence tomography system, based on photonic integrated circuit (PIC) technology. The integrated optics 512-channel spectrometer consists of cascaded arrayed waveguide gratings (AWG) with the output waveguides directly attached to a CCD detector. The spectrometer has a center wavelength of 850 nm and a spectral sampling interval of 0.22 nm. The PIC has a footprint of 2.0 2.7 ...
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  Mentions: Academic Medical Center at the University of Amsterdam Dirk J. Faber Ton G. van Leeuwen
13. Micro-indentation and optical coherence tomography for the mechanical characterization of embryos: Experimental setup and measurements on fixed chicken embryos.
  
  Explore bioRxiv.org Feb 28 2019 Developmental Biology
  
  The investigation of the mechanical properties of embryos is expected to provide valuable information on the phenomenology of morphogenesis. It is thus believed that, by mapping the viscoelastic features of an embryo at different stages of growth, it may be possible to shed light on the role of mechanics in embryonic development. To contribute to this field, we present a new instrument that can determine spatiotemporal distributions of mechanical properties ...
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  Mentions: Academic Medical Center at the University of Amsterdam VU University Amsterdam University Medical Center Utrecht
14. From sample structure to optical properties and back : A theoretical framework for quantitative OCT and its clinical application (Thesis)
  
  Explore NARCIS > Home Dec 6 2018 Student Theses
  
  The aim of this thesis is to provide a methodology to extract quantitative parameters from optical coherence tomography (OCT) images and to relate these parameters to sample properties such as structure, organization and flow. OCT uses near-infrared light to acquire 3D images of biological tissue, with a resolution around 5-15 m and an imaging depth of approximately 2 mm. OCT can be a useful clinical tool for minimally-invasive, high-resolution imaging ...
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  Mentions: Academic Medical Center at the University of Amsterdam Dirk J. Faber Ton G. van Leeuwen
15. Acute Airway Effects of Bronchial Thermoplasty Assessed by Optical Coherence Tomography (OCT)
  
  Explore European Respiratory Journal Nov 27 2018 Pulmonology
  
  Background: Bronchial Thermoplasty (BT) is an endoscopic treatment for severe asthma targeting airway smooth muscle (ASM) with thermal energy. The extent of treatment effect is largely unknown. Optical coherence tomography (OCT) is a high resolution imaging technique, using near-infrared light, that generates near-histology cross sectional images of the airway wall. Aim: Assess the extent of acute airway wall effects of BT with OCT and compare these to the untreated right ...
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  Mentions: Academic Medical Center at the University of Amsterdam Daniël M. de Bruin
16. Optical Coherence Tomography in Urologic Oncology: a Comprehensive Review
  
  Explore Home - Springer Nov 27 2018 Urology
  
  Introduction Optical coherence tomography (OCT) is being investigated in urologic oncology for optical diagnosis. This comprehensive review analyzes the current state of development of OCT for bladder, upper urinary tract, kidney, prostate, testis, and penis cancer. Also, the potential role of OCT with regard to the current diagnostic pathways is critically appraised to guide future developments. Methods Embase and Pubmed were systematically searched for English and German articles on OCT ...
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  Mentions: Academic Medical Center at the University of Amsterdam Ton G. van Leeuwen Daniël M. de Bruin
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