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Academic Medical Center at the University of Amsterdam

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2. Tissue characterization with depth-resolved attenuation coefficient and backscatter term in intravascular optical coherence tomography images
  
  Explore SPIE Digital Library Sep 17 2017 Cardiology
  
  An important application of intravascular optical coherence tomography (IVOCT) for atherosclerotic tissue analysis is using it to estimate attenuation and backscatter coefficients. This work aims at exploring the potential of the attenuation coefficient, a proposed backscatter term, and image intensities in distinguishing different atherosclerotic tissue types with a robust implementation of depth-resolved (DR) approach. Therefore, the DR model is introduced to estimate the attenuation coefficient and further extended to estimate ...
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  Mentions: Leiden University Academic Medical Center at the University of Amsterdam Patrick W. Serruys
3. Applicability of quantitative optical imaging techniques for intraoperative perfusion diagnostics: a comparison of laser speckle contrast imaging, sidestream dark-field microscopy, and optical coherence tomography
  
  Explore SPIE Digital Library Sep 2 2017
  
  . Patient morbidity and mortality due to hemodynamic complications are a major problem in surgery. Optical techniques can image blood flow in real-time and high-resolution, thereby enabling perfusion monitoring intraoperatively. We tested the feasibility and validity of laser speckle contrast imaging (LSCI), optical coherence tomography (OCT), and sidestream dark-field microscopy (SDF) for perfusion diagnostics in a phantom model using whole blood. Microvessels with diameters of 50, 100, and 400 m were ...
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  Mentions: Academic Medical Center at the University of Amsterdam Dirk J. Faber Ton G. van Leeuwen
4. EuOptical coherence tomography findings: insights from the “randomised multicentre trial investigating angiographic outcomes of hybrid sirolimus-eluting stents with biodegradable polymer compared with everolimus-eluting stents with durable polymer in chro
  
  Explore eurointervention.org Aug 20 2017 Cardiology
  
  Aims: The PRISON IV trial investigated the next-generation sirolimus-eluting stent (SES) with ultra-thin struts and biodegradable polymer against the second-generation everolimus-eluting stent (EES) with thin struts and durable polymer in patients with successfully recanalised chronic total occlusions (CTO). In this study, we examined the secondary optical coherence tomography endpoints. Methods and results: The main PRISON IV trial randomised 330 patients to either SES or EES. At nine months, 281 (85 ...
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  Mentions: Academic Medical Center at the University of Amsterdam Walter Desmet K. U. Leuven
5. Optical coherence tomography findings: insights from the “randomised multicentre trial investigating angiographic outcomes of hybrid sirolimus-eluting stents with biodegradable polymer compared with everolimus-eluting stents with durable polymer in chroni
  
  Explore eurointervention.org May 28 2017 Cardiology
  
  Aims: The PRISON IV trial investigated the next-generation sirolimus-eluting stent (SES) with ultra-thin struts and biodegradable polymer against the second-generation everolimus-eluting stent (EES) with thin struts and durable polymer in patients with successfully recanalised chronic total occlusions (CTO). In this study, we examined the secondary optical coherence tomography endpoints. Methods and results: The main PRISON IV trial randomised 330 patients to either SES or EES. At nine months, 281 (85 ...
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  Mentions: Arnaud Dubois Academic Medical Center at the University of Amsterdam Walter Desmet
6. Optical coherence tomography findings: insights from the “randomised multicentre trial investigating angiographic outcomes of hybrid sirolimus-eluting stents with biodegradable polymer compared with everolimus-eluting stents with durable polymer in chroni
  
  Explore eurointervention.org May 18 2017 Cardiology
  
  Aims: The PRISON IV trial investigated the next-generation sirolimus-eluting stent (SES) with ultra-thin struts and biodegradable polymer against the second-generation everolimus-eluting stent (EES) with thin struts and durable polymer in patients with successfully recanalised chronic total occlusions (CTO). In this study, we examined the secondary optical coherence tomography endpoints. Methods and results: The main PRISON IV trial randomised 330 patients to either SES or EES. At nine months, 281 (85 ...
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  Mentions: Academic Medical Center at the University of Amsterdam Walter Desmet K. U. Leuven
7. Is quantitative coronary angiography reliable in assessing the late lumen loss of the everolimus eluting bioresorbable polylactide scaffold in comparison with the cobalt chromium metallic stent?
  
  Explore eurointervention.org Mar 11 2017 Cardiology
  
  Aims: Immediately after stent/scaffold implantation, quantitative coronary angiography (QCA) with respect to optical coherence tomography (OCT) more severely underestimates the lumen diameter (LD) in Absorb than in XIENCE. This OCT-QCA discrepancy has not been evaluated at long-term follow-up. The present study aimed to assess the accuracy of QCA with reference to OCT in Absorb as compared to XIENCE.
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  Mentions: Beth Israel Deaconess Medical Center Columbia University Leiden University
8. The REMEDEE-OCT Study : An Evaluation of the Bioengineered COMBO Dual-Therapy CD34 Antibody–Covered Sirolimus-Eluting Coronary Stent Compared With a Cobalt-Chromium Everolimus-Eluting Stent in Patients With Acute Coronary Syndromes: Insights From Optical
  
  Explore ScienceDirect Mar 11 2017 Cardiology
  
  Objectives The aim of the present study was to evaluate vascular healing of the bioengineered COMBO Dual Therapy Stent compared with a cobalt-chromium (CoCr) everolimus-eluting stent (EES) as assessed by optical coherence tomography in patients with acute coronary syndromes. Background CD34+ cells promote endothelial repair after vascular injury. The bioengineered COMBO Dual Therapy Stent combines CD34+ cellcapturing technology with abluminal sirolimus release, but more data from clinical studies evaluating the ...
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  Mentions: Case Western Reserve University Cardiovascular Research Foundation Academic Medical Center at the University of Amsterdam
9. Enhanced Diagnostic Capability for Glaucoma of 3-Dimensional Versus 2-Dimensional Neuroretinal Rim Parameters Using Spectral Domain Optical Coherence Tomography
  
  Explore LWW Online Mar 1 2017 Ophthalmology
  
  Purpose: To compare the diagnostic capability of 3-dimensional (3D) neuroretinal rim parameters with existing 2-dimensional (2D) neuroretinal and retinal nerve fiber layer (RNFL) thickness rim parameters using spectral domain optical coherence tomography (SD-OCT) volume scans. Materials and Methods: Design: Institutional prospective pilot study. Study population: 65 subjects (35 open-angle glaucoma patients, 30 normal patients). Observation procedures: One eye of each subject was included. SD-OCT was used to obtain 2D RNFL ...
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  Mentions: Johannes F. de Boer Johns Hopkins University Harvard University
10. Optical coherence tomography and confocal laser endomicroscopy in pulmonary diseases
  
  Explore LWW Online Feb 22 2017 Pulmonology
  
  Purpose of review: Current imaging techniques (X-ray, computed tomography scan, ultrasound) have limitations in the identification and quantification of pulmonary diseases, in particular, on highly detailed level. The purpose of this review is to provide an overview of the current knowledge of innovative light- and laser-based imaging techniques that might fill this gap. Recent findings: Optical coherence tomography (OCT) and confocal laser endomicroscopy (CLE) are high-resolution imaging techniques, which, combined ...
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  Mentions: Academic Medical Center at the University of Amsterdam
11. Feasibility of laser marking in Barrett’s esophagus with volumetric laser endomicroscopy: first-in-man pilot study
  
  Explore Gastrointestinal Endoscopy Feb 1 2017 Gastroenterology , Oncology
  
  Background and Aim Volumetric laser endomicroscopy (VLE) provides a circumferential scan of the esophageal wall layers and has potential to improve detection of neoplasia in Barretts esophagus (BE). The novel VLE laser marking system enables direct in vivo marking of suspicious areas as identified on VLE. These laser marked areas can subsequently be targeted for biopsies. The aim was to evaluate the visibility and positional accuracy of laser marks (LMs ...
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  Mentions: Academic Medical Center at the University of Amsterdam NinePoint Medical
12. New technologies for upper tract urothelial carcinoma management
  
  Explore LWW Online Jan 27 2017 Oncology , Urology
  
  Purpose of review: Image enhancement techniques and optical diagnostic tools have emerged in the quest to improve diagnostics and treatment in patients with upper urinary tract carcinoma (UTUC). The aim of the present report is to describe their mechanisms of action and to assess the current evidence on applicability and utility in UTUC. Recent findings: Image enhancement techniques including narrow band imaging, Image1 S, and photodynamic diagnosis aim at better ...
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  Mentions: Academic Medical Center at the University of Amsterdam Jean J. M. C. H. de la Rosette
13. Intracoronary optical coherence tomography: Clinical and research applications and intravascular imaging software overview
  
  Explore Wiley Online Library Jan 21 2017 Cardiology
  
  By providing valuable information about the coronary artery wall and lumen, intravascular imaging may aid in optimizing interventional procedure results and thereby could improve clinical outcomes following percutaneous coronary intervention (PCI). Intravascular optical coherence tomography (OCT) is a light-based technology with a tissue penetration of approximately 1 to 3 mm and provides near histological resolution. It has emerged as a technological breakthrough in intravascular imaging with multiple clinical and research ...
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  Mentions: Imperial College London Leiden University University College London
14. Non-moving scanner design for OCT systems
  
  Explore OSA | OSA Publishing Dec 14 2016 Probes
  
  n this work, a novel beam scanner design based on non-moving parts is introduced which will eliminate the phase and inaccuracy problems of the mechanical scanners while providing two times imaging speed improvement for optical coherence tomography systems. The design is comprised of electro-optically activated switches that are placed on the sample arm. For the example considered here, lateral resolution of 20 m, and lateral scanning range of 1 mm ...
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  Mentions: Academic Medical Center at the University of Amsterdam B. Imran Akca
15. Design of a high-speed multiple-reference optical coherence tomography system
  
  Explore OSA | OSA Publishing Nov 15 2016
  
  he imaging speed of a time domain optical coherence tomography (OCT) system is limited by the speed of the moving mirror. As a solution to this problem an integrated-optics-based multiple-reference TD-OCT system is presented in this work. The reference and sample lights will be sequentially tapped out at multiple locations using electro-optically controlled switches. For the design considered here an axial resolution of 20 m and a depth range of ...
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  Mentions: Academic Medical Center at the University of Amsterdam B. Imran Akca
16. Optical coherence tomography attenuation imaging for lipid core detection: an ex-vivo validation study
  
  Explore Home - Springer Sep 14 2016 Cardiology
  
  Lipid-core atherosclerotic plaques are associated with disease progression, procedural complications, and cardiac events. Coronary plaque lipid can be quantified in optical coherence tomography (OCT) pullbacks by measurement of lipid arcs and lipid lengths; parameters frequently used in clinical research, but labor intensive and subjective to analyse. In this study, we investigated the ability of quantitative attenuation, derived from intravascular OCT, to detect plaque lipid. Lipid cores are associated with a ...
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  Mentions: Academic Medical Center at the University of Amsterdam Evelyn Regar Delft University of Technology
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