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Academic Medical Center at the University of Amsterdam

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1. Mentioned In 175 Articles
2. Longitudinal retinal layer changes in preclinical Alzheimer’s disease
  
  Explore Wiley Online Library Oct 21 2020 Neurology , Ophthalmology
  
  Purpose Several studies found reduced retinal thickness on optical coherence tomography (OCT) in Alzheimers disease (AD), even in preclinical stages, labelling this technique of interest as biomarker. In this study, we examine retinal thickness changes in preclinical AD, as defined by cognitively normal individuals with amyloid‐beta (A) on positron emission tomography (PET). Methods For this monocentre study, 145 cognitively healthy monozygotic twins aged 60 were included from the Netherlands ...
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  Mentions: Academic Medical Center at the University of Amsterdam Frank D. Verbraak
3. 3D co-registration algorithm for catheter-based optical coherence tomography
  
  Explore OSA | OSA Publishing Sep 21 2020
  
  Applications of catheter-based optical coherence tomography (OCT) - originally developed for cardiovascular imaging - have expanded to other organ systems. However, currently available algorithms to co-register 3D OCT data to a second imaging modality were developed for cardiovascular applications and with it, are tailored to small tubular tissue structures. The available algorithms can often not be applied outside the cardiovascular system, e.g. when an OCT probe is introduced into the kidney ...
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  Mentions: Academic Medical Center at the University of Amsterdam Dirk J. Faber Ton G. van Leeuwen
4. Advances in IVUS/OCT and Future Clinical Perspective of Novel Hybrid Catheter System in Coronary Imaging
  
  Explore Frontiers Aug 29 2020
  
  Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) have been developed and improved as both diagnostic and guidance tools for interventional procedures over the past three decades. IVUS has a resolution of 100 m with a high tissue penetration and capability of assessing the entire structure of a coronary artery including the external elastic membrane, whereas OCT has a higher resolution of 1020 m to assess endoluminal structures with a ...
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  Mentions: University of Toronto Terumo Corporation Academic Medical Center at the University of Amsterdam
5. Common-path integrated low coherence interferometry system and method therefor
  
  Explore uspto.gov Aug 25 2020 Patents
  
  A low coherence interferometry imaging system comprising a common-path interferometer that is at least partially integrated as part of a planar lightwave circuit is disclosed. Imaging systems in accordance with the present invention are implemented in integrated optics without the inclusion of highly wavelength-sensitive components. As a result, they exhibit less wavelength dependence than PLC-based interferometers of the prior art. Further, the common-path interferometer arrangement of the present invention avoids ...
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  Mentions: Academic Medical Center at the University of Amsterdam Ton G. van Leeuwen
6. Comparison of Optical Imaging Techniques to Quantitatively Assess the Perfusion of the Gastric Conduit during Oesophagectomy
  
  Explore MDPI Open Access Journals Platform Aug 10 2020 Gastroenterology
  
  In this study, four optical techniquesOptical Coherence Tomography, Sidestream Darkfield Microscopy, Laser Speckle Contrast Imaging, and Fluorescence Angiography (FA)were compared on performing an intraoperative quantitative perfusion assessment of the gastric conduit during oesophagectomy. We hypothesised that the quantitative parameters show decreased perfusion towards the fundus in the gastric conduit and in patients with anastomotic leakage. In a prospective study in patients undergoing oesophagectomy with gastric conduit reconstruction, measurements were ...
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  Mentions: Academic Medical Center at the University of Amsterdam Ton G. van Leeuwen Daniël M. de Bruin
7. CLE and OCT in Acute Respiratory Insufficiency
  
  Explore Home - ClinicalTrials.gov Jul 21 2020 Pulmonology , Clinical Trials
  
  Acute respiratory distress syndrome is a severe complication of critical illness. The diagnosis of ARDS is difficult, and it could be important to differentiate ARDS from other causes of acute respiratory failure. Innovative probe-based imaging techniques such as 'Confocal Laser Endomicroscopy' (CLE) and Optical Coherence Tomography (OCT) are high resolution optical techniques that, combined with conventional bronchoscopy, have been found to provide non-invasive, real-time near-histology information about the alveolar compartment ...
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  Mentions: Academic Medical Center at the University of Amsterdam
8. The analysis of prostate tissue by optical coherence tomography (Thesis)
  
  Explore Research Explorer Jul 6 2020 Urology , Student Theses
  
  The prostate is the gland located around the urethra beneath the bladder that produces most of the sperm fluid (figure 1). Prostate cancer (PCa) accounted for almost 1 in 5 new cancer diagnoses in males in the USA in 2017, and 1 in 8 men will develop invasive cancer in the prostate in their lifetime [1]. Prostate cancer is the second most common cancer in men (after skin cancer) and ...
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  Mentions: Academic Medical Center at the University of Amsterdam
9. Illuminating the trapeziometacarpal joint: Dawn for optical coherence tomography in osteoarthritis (Thesis)
  
  Explore UvA DARE Jun 15 2020 Student Theses
  
  Osteoarthritis (OA) is a debilitating degenerative joint disease affecting millions of patients worldwide and is characterized by loss of cartilage thickness and quality in affected joints. OA of the trapeziometacarpal (TMC) joint or thumb base joint especially gives rise to loss of hand function and disability. However, clinical imaging strategies have thus far been unable to accurately assess the thin cartilage layers lining small joints like the TMC joint. Moreover ...
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  Mentions: Academic Medical Center at the University of Amsterdam
10. Optical Coherence Tomography Intensity Correlates with Extracellular Matrix Components in the Airway Wall
  
  Explore Home (thoracic) May 5 2020 Pulmonology
  
  No abstract provided.
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  Mentions: Academic Medical Center at the University of Amsterdam University of Groningen Daniël M. de Bruin
11. Parametric imaging of attenuation by optical coherence tomography: review of models, methods, and clinical translation
  
  Explore SPIE Digital Library Apr 20 2020
  
  Significance: Optical coherence tomography (OCT) provides cross-sectional and volumetric images of backscattering from biological tissue that reveal the tissue morphology. The strength of the scattering, characterized by an attenuation coefficient, represents an alternative and complementary tissue optical property, which can be characterized by parametric imaging of the OCT attenuation coefficient. Over the last 15 years, a multitude of studies have been reported seeking to advance methods to determine the OCT ...
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  Mentions: David D. Sampson University of Western Australia Academic Medical Center at the University of Amsterdam
12. In vivo characterization of chick embryo mesoderm by optical coherence tomography assisted microindentation
  
  Explore bioRxiv.org Mar 17 2020 Cardiology , Developmental Biology
  
  Embryos are growing organisms with highly heterogeneous properties in space and time. Understanding the mechanical properties is a crucial prerequisite for the investigation of morphogenesis. During the last ten years, new techniques have been developed to evaluate the mechanical properties of biological tissues in vivo . To address this need, we employed a new instrument that, via the combination of micro-indentation with Optical Coherence Tomography (OCT), allows us to determine both ...
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  Mentions: Academic Medical Center at the University of Amsterdam VU University Amsterdam
13. En‐face optical coherence tomography for the detection of cancer in prostatectomy specimens: quantitative analysis in 20 patients
  
  Explore Wiley Online Library Feb 21 2020 Urology
  
  The increase histopathological evaluation of prostatectomy specimens rises the workload on pathologists. Automated histopathology systems, preferably directly on unstained specimens, would accelerate the pathology workflow. In this study, we investigate the potential of quantitative analysis of Optical Coherence Tomography (OCT) to separate benign from malignant prostate tissue automatically. Twenty fixated prostates were cut, from which 54 slices were scanned by OCT. Quantitative OCT metrics (attenuation coefficient, residue, goodness‐of‐fit ...
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  Mentions: Academic Medical Center at the University of Amsterdam Dirk J. Faber Ton G. van Leeuwen
14. Randomized Comparison Between Everolimus-Eluting Bioresorbable Scaffold and Metallic Stent Multimodality Imaging Through 3 Years
  
  Explore interventions.onlinejacc.org Jan 12 2020 Cardiology
  
  Objectives The aim of this study was to investigate the vascular responses and fates of the scaffold after bioresorbable vascular scaffold (BVS) implantation using multimodality imaging. Background Serial comprehensive image assessments after BVS implantation in the context of a randomized trial have not yet been reported. Methods In the ABSORB Japan trial, 400 patients were randomized to a BVS (n = 266) or a cobalt-chromium everolimus-eluting stent (n = 134). Through 3 ...
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  Mentions: Beth Israel Deaconess Medical Center Columbia University Stanford University
15. Advances in Optical Coherence Tomography and Confocal Laser Endomicroscopy in Pulmonary Diseases
  
  Explore Karger Publishers Oct 14 2019 Pulmonology
  
  Diagnosing and monitoring pulmonary diseases is highly dependent on imaging, physiological function tests and tissue sampling. Optical coherence tomography (OCT) and confocal laser endomicroscopy (CLE) are novel imaging techniques with near-microscopic resolution that can be easily and safely combined with conventional bronchoscopy. Disease-related pulmonary anatomical compartments can be visualized, real time, using these techniques. In obstructive lung diseases, airway wall layers and related structural remodelling can be identified and quantified ...
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  Mentions: Academic Medical Center at the University of Amsterdam
16. Computed Tomography–Mediated Registration of Trapeziometacarpal Articular Cartilage Using Intraarticular Optical Coherence Tomography and Cryomicrotome Imaging: A Cadaver Study
  
  Explore SAGE Journals Jul 16 2019
  
  Objective Accurate, high-resolution imaging of articular cartilage thickness is an important clinical challenge in patients with osteoarthritis, especially in small joints. In this study, computed tomography (CT) mediated catheter-based optical coherence tomography (OCT) was utilized to create a digital reconstruction of the articular surface of the trapeziometacarpal (TMC) joint and to assess cartilage thickness in comparison to cryomicrotome data. Design Using needle-based introduction of the OCT probe, the articular surface ...
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  Mentions: Academic Medical Center at the University of Amsterdam Ton G. van Leeuwen Daniël M. de Bruin
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