Articles that mention Academic Medical Center at the University of Amsterdam -Optical Coherence Tomography News

Academic Medical Center at the University of Amsterdam

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1. Mentioned In 188 Articles
2. Sodium-Iodate Injection Can Replicate Retinal Degenerative Disease Stages in Pigmented Mice and Rats: Non-Invasive Follow-Up Using OCT and ERG
  
  Explore MDPI Open Access Journals Platform Mar 26 2022 Ophthalmology
  
  Purpose: The lack of suitable animal models for (dry) age-related macular degeneration (AMD) has hampered therapeutic research into the disease, so far. In this study, pigmented rats and mice were systematically injected with various doses of sodium iodate (SI). After injection, the retinal structure and visual function were non-invasively characterized over time to obtain in-depth data on the suitability of these models for studying experimental therapies for retinal degenerative diseases ...
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  Mentions: National Institutes of Health Academic Medical Center at the University of Amsterdam University of Bonn
3. Detection of Vulnerable Coronary Plaques Using Invasive and Non-Invasive Imaging Modalities
  
  Explore MDPI Open Access Journals Platform Mar 11 2022 Cardiology
  
  Acute coronary syndrome (ACS) mostly arises from so-called vulnerable coronary plaques, particularly prone for rupture. Vulnerable plaques comprise a specific type of plaque, called the thin-cap fibroatheroma (TFCA). A TCFA is characterized by a large lipid-rich necrotic core, a thin fibrous cap, inflammation, neovascularization, intraplaque hemorrhage, microcalcifications or spotty calcifications, and positive remodeling. Vulnerable plaques are often not visible during coronary angiography. However, different plaque features can be visualized with ...
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  Mentions: Academic Medical Center at the University of Amsterdam
4. Endobronchial Optical Coherence Tomography: Shining New Light on Diagnosing UIP?
  
  Explore Home (thoracic) Feb 12 2022 Pulmonology
  
  To the editor: In 15-30% of patients with a fibrotic interstitial lung disease (ILD) tissue acquisition is indicated as the diagnostic confidence based on clinical and radiological investigations does not justify a specific treatment allocation [1]. However, surgical lung biopsy and transbronchial cryobiopsy are associated with considerable risks of morbidity and even mortality [2]. Minimally invasive imaging techniques have the potential to obviate the need for tissue biopsy in at ...
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  Mentions: Academic Medical Center at the University of Amsterdam VU University Amsterdam
5. Polarization Sensitive Optical Coherence Tomography for Bronchoscopic Airway Smooth Muscle Detection in Bronchial Thermoplasty-Treated Patients With Asthma
  
  Explore ScienceDirect Sep 1 2021 Pulmonology
  
  Asthma is a chronic inflammatory disease characterized by airway remodeling (AR), including thickening of airway smooth muscle (ASM) as a key element of this alteration. 1 Patients with severe asthma may benefit from bronchial thermoplasty (BT), an endoscopic treatment that targets structural AR and induces ASM reduction. 2 Assessment of AR is critical to evaluate the impact of BT and might provide a tool for patient selection for BT. Polarization ...
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  Mentions: Academic Medical Center at the University of Amsterdam VU University Amsterdam
6. Optical coherence tomography (OCT) and irreversible electroporation (IRE) in the diagnosis and treatment of renal masses
  
  Explore UvA DARE Jun 3 2021 Student Theses
  
  The first aim of this thesis is to investigate the diagnostic value of needle-based, percutaneous optical coherence tomography (OCT) in the differentiation of renal masses. Secondly, the feasibility and safety of percutaneous, irreversible electroporation (IRE) are assessed for the treatment of SRMs.
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  Mentions: Academic Medical Center at the University of Amsterdam
7. Optical coherence tomography to measure the progression of myelopathy in adrenoleukodystrophy
  
  Explore Wiley Online Library Apr 1 2021 Ophthalmology
  
  Objective: To prospectively determine the value of optical coherence tomography (OCT) as a surrogate outcome measure for the progression of myelopathy in males with adrenoleukodystrophy. Methods: Retinal nerve fiber layer (RNFL) and ganglion cell layer (GCL) thickness were measured at baseline, 1- and 2-year follow-up in patients and age-matched controls. We assessed the severity of myelopathy with clinical parameters: Expanded Disability Status Scale (EDSS), Severity Scoring system for Progressive Myelopathy ...
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  Mentions: Academic Medical Center at the University of Amsterdam
8. Polarization sensitive optical coherence tomography (PS-OCT) for bronchoscopic airway smooth muscle detection in bronchial thermoplasty treated asthma patients
  
  Explore CHEST Apr 1 2021 Pulmonology
  
  To the editor, 79 Asthma is a chronic inflammatory disease characterized by airway remodeling (AR), 80 including thickening of airway smooth muscle (ASM) as a key element of this alteration (1). 81 Severe asthma patients may benefit from bronchial thermoplasty (BT), an endoscopic 82 treatment that targets structural AR and induces ASM reduction (2). Assessment of AR is 83 critical to evaluate the impact of BT and might provide a ...
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  Mentions: Academic Medical Center at the University of Amsterdam VU University Amsterdam
9. Optical Coherence Tomography-Guided PCI With Single-Antiplatelet Therapy
  
  Explore Home - ClinicalTrials.gov Feb 23 2021 Cardiology , Clinical Trials
  
  Rationale: Dual antiplatelet therapy (DAPT), consisting of aspirin and a P2Y12-inhibitor, reduces the risk of stent thrombosis, myocardial infarction and stroke after coronary stent implantation. Inevitably, it is also associated with a higher risk of (major) bleeding. Given the advances in stent properties, stenting implantation technique and pharmacology, it may be possible to treat patients with a single antiplatelet strategy using a potent P2Y12- inhibitor such as prasugrel. Objective: This ...
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  Mentions: Academic Medical Center at the University of Amsterdam
10. Single-chip optical coherence tomography device
  
  Explore uspto.gov Feb 2 2021 Patents
  
  A high-performance single-chip, integrated-optics-based OCT system is disclosed, where the length of the reference arm is digitally variable. The reference arm includes a plurality of switch stages comprising a 2.times.2 tunable wavelength-independent waveguide switch that can direct an input light signal onto either of two different-length output waveguides. In some embodiments, the directional couplers are thermo-optic based. Some embodiments include a solid-state scanning system for scanning a sample ...
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  Mentions: Academic Medical Center at the University of Amsterdam
11. Bayesian analysis of depth resolved OCT attenuation coefficients
  
  Explore Nature Publishing Group Jan 26 2021
  
  Biomedical engineering Abstract Optical coherence tomography (OCT) is an optical technique which allows for volumetric visualization of the internal structures of translucent materials. Additional information can be gained by measuring the rate of signal attenuation in depth. Techniques have been developed to estimate the rate of attenuation on a voxel by voxel basis. This depth resolved attenuation analysis gives insight into tissue structure and organization in a spatially resolved way.
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  Mentions: Academic Medical Center at the University of Amsterdam
12. In vivo characterization of chick embryo mesoderm by optical coherence tomography‐assisted microindentation
  
  Explore faseb.onlinelibrary.wiley.com Jan 9 2021
  
  Embryos are growing organisms with highly heterogeneous properties in space and time. Understanding the mechanical properties is a crucial prerequisite for the investigation of morphogenesis. During the last 10 years, new techniques have been developed to evaluate the mechanical properties of biological tissues in vivo. To address this need, we employed a new instrument that, via the combination of micro‐indentation with Optical Coherence Tomography (OCT), allows us to determine ...
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  Mentions: Academic Medical Center at the University of Amsterdam
13. Quantification of key retinal features in early and late age-related macular degeneration using deep learning
  
  Explore American Journal of Ophthalmology Jan 7 2021 Ophthalmology
  
  Purpose To develop and validate a deep learning model for segmentation of 13 features associated with neovascular and atrophic age-related macular degeneration (AMD). Design Development and validation of a deep-learning model for feature segmentation Methods Data for model development were obtained from 307 optical coherence tomography volumes. Eight experienced graders manually delineated all abnormalities in 2,712 B-scans. A deep neural network was trained with this data to perform voxel-level ...
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  Mentions: Academic Medical Center at the University of Amsterdam Erasmus University
14. Optical coherence tomography (OCT) in neuro-ophthalmology
  
  Explore Nature Publishing Group Nov 25 2020 Ophthalmology
  
  Optical coherence tomography (OCT) is a non-invasive medical imaging technology that is playing an increasing role in the routine assessment and management of patients with neuro-ophthalmic conditions. Its ability to characterise the optic nerve head, peripapillary retinal nerve fibre layer and cellular layers of the macula including the ganglion cell layer enables qualitative and quantitative assessment of optic nerve disease. In this review, we discuss technical features of OCT and ...
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  Mentions: University College London Academic Medical Center at the University of Amsterdam
15. Longitudinal retinal layer changes in preclinical Alzheimer’s disease
  
  Explore Wiley Online Library Oct 21 2020 Neurology , Ophthalmology
  
  Purpose Several studies found reduced retinal thickness on optical coherence tomography (OCT) in Alzheimers disease (AD), even in preclinical stages, labelling this technique of interest as biomarker. In this study, we examine retinal thickness changes in preclinical AD, as defined by cognitively normal individuals with amyloid‐beta (A) on positron emission tomography (PET). Methods For this monocentre study, 145 cognitively healthy monozygotic twins aged 60 were included from the Netherlands ...
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  Mentions: Academic Medical Center at the University of Amsterdam
16. 3D co-registration algorithm for catheter-based optical coherence tomography
  
  Explore OSA | OSA Publishing Sep 21 2020
  
  Applications of catheter-based optical coherence tomography (OCT) - originally developed for cardiovascular imaging - have expanded to other organ systems. However, currently available algorithms to co-register 3D OCT data to a second imaging modality were developed for cardiovascular applications and with it, are tailored to small tubular tissue structures. The available algorithms can often not be applied outside the cardiovascular system, e.g. when an OCT probe is introduced into the kidney ...
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  Mentions: Academic Medical Center at the University of Amsterdam
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