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1. Mentioned In 39 Articles
2. Capillary stall quantification from optical coherence tomography angiogram maximum intensity projections
  
  Explore bioRxiv.org Oct 2 2021 Ophthalmology
  
  Optical coherence tomography (OCT) is applicable to the study of cerebral microvasculature in vivo. Optimised acquisition schemes enable the generation of three-dimensional OCT angiograms, i.e., volumetric images of red blood cell flux in capillary networks, currently at a repetition rate of up to 1/10 seconds. This makes testable a new class of hypotheses that strive to bridge the gap between microscopic phenomena occurring at the spatial scale of ...
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  Mentions: Chinese Academy of Sciences Aarhus University
3. Automatic Characterisation of Human Atherosclerotic Plaque Composition from Intravascular Optical Coherence Tomography Using Artificial Intelligence
  
  Explore eurointervention.pcronline.com Feb 2 2021 Cardiology
  
  Background Intravascular optical coherence tomography (IVOCT) enables detailed plaque characterisation in-vivo, but visual assessment is time-consuming and subjective. Aims This study aims to develop and validate an automatic framework for IVOCT plaque characterisation using artificial intelligence (AI). Methods IVOCT pullbacks from 5 international centres were analysed in a corelab, annotating basic plaque components, inflammatory markers and other structures. A deep convolutional network with encoding-decoding architecture and pseudo-3D input was developed ...
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  Mentions: Cardiovascular Research Foundation Wakayama Medical University Chinese Academy of Sciences
4. Imaging of Cardiac Transplantation: An Overview
  
  Explore ScienceDirect Jan 20 2021 Cardiology
  
  Heart transplantation (HTx) remains the optimal treatment for selected patients with end-stage advanced heart failure. However, survival is limited early by acute rejection and long term by cardiac allograft vasculopathy (CAV). Even though the diagnosis of rejection is based on histology, cardiac imaging provides a pivotal role for early detection and severity assessment of these hazards. The present review focuses on the use and reliability of different invasive and non-invasive ...
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  Mentions: Aarhus University
5. Culprit lesion morphology in patients with ST-segment elevation myocardial infarction assessed by optical coherence tomography
  
  Explore LWW Online Sep 3 2020 Cardiology
  
  Aims This study sought to evaluate the incidence of ruptured plaques and nonruptured plaques (NRP) and to compare patient characteristics and detailed plaque morphology features between the two culprit types in ST-segment elevation myocardial infarction (STEMI) patients, using optical coherence tomography (OCT). Methods and results Using OCT, the culprit lesions in patients with STEMI were assessed prior to stent implantation. The culprit lesion was categorized as ruptured plaques or NRP ...
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  Mentions: Cardiovascular Research Foundation Aarhus University
6. Fractional flow reserve in clinical practice: from wire-based invasive measurement to image-based computation
  
  Explore Journals Dec 30 2019 Cardiology
  
  ...hina (81871460) and by the Program of Shanghai Technology Research Leader. J.W. acknowledges the support from Aarhus University (PhD scholarship). W.W. is the recipient of a Research Professorship Award, by Science Found...
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  Mentions: Leiden University Boston Scientific Abbott
7. First Report of Edge Vascular Response at 12 Months of Magmaris, A Second-Generation Drug-Eluting Resorbable Magnesium Scaffold, Assessed by Grayscale Intravascular Ultrasound, Virtual Histology, and Optical Coherence Tomography. A Biosolve-II Trial Sub-S
  
  Explore ScienceDirect May 23 2019 Cardiology
  
  Introduction and objective The edge vascular response (EVR) remains unknown in second generation drug-eluting Resorbable Magnesium Scaffold (RMS), such as Magmaris. The aim of the study was to evaluate tissue modifications in the RMS edges over time, assessed by different invasive imaging modalities. Methods The patients treated with the device were assessed by optical coherence tomography (OCT), grayscale intravascular ultrasound (IVUS), and virtual histology IVUS at baseline and 12 months ...
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  Mentions: University of São Paulo Universität Rostock University of Lausanne
8. Mechanical performance and healing patterns of the novel sirolimus-eluting bioresorbable Fantom scaffold: 6-month and 9-month follow-up by optical coherence tomography in the FANTOM II study
  
  Explore Open Heart Mar 6 2019 Cardiology
  
  Objectives We aimed to evaluate the mechanical properties and healing patterns 6 and 9 months after implantation of the sirolimus-eluting Fantom bioresorbable scaffold (BRS). Background The Fantom BRS (Reva Medical, San Diego, USA) has differentiating properties including radiopacity, strut thickness of 125 m, high expansion capacity and has demonstrated favourable mid-term clinical and angiographic outcomes. Methods and results FANTOM II was a prospective, single arm study with implantation of the ...
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  Mentions: Leiden University Erasmus University Aarhus University
9. Rational and Design of the European Randomized Optical Coherence Tomography Optimized Bifurcation Event Reduction Trial (OCTOBER)
  
  Explore ScienceDirect Aug 21 2018 Cardiology
  
  Background Percutaneous coronary intervention (PCI) in complex bifurcation lesions is prone to suboptimal implantation results and is associated with increased risk of subsequent clinical events. Angiographic ambiguity is high during bifurcation stenting but it is unknown if procedural guidance by intravascular optical coherence tomography (OCT) improves clinical outcome. Methods and design OCTOBER is a randomized, investigator initiated, multi-center trial aimed to show superiority of OCT guided stent implantation compared to ...
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  Mentions: Tampere University of Technology VU University Amsterdam Aarhus University
10. Plaque Burden Influences Accurate Classification of Fibrous Cap Atheroma by In-Vivo Optical Coherence Tomography in a Porcine Model of Advanced Coronary Atherosclerosis
  
  Explore eurointervention.org Apr 16 2018 Cardiology
  
  Aims: In-vivo validation of coronary optical coherence tomography (OCT) against histology and the effects of plaque burden (PB) on plaque classification remain unreported. We investigated this in a porcine model with human-like coronary atherosclerosis. Methods and results: Five female Yucatan D374Y-PCSK9 transgenic hypercholesterolemic mini-pigs were implanted with a coronary shear-modifying stent to induce advanced atherosclerosis. OCT frames (n=201) were obtained 34 weeks after implantation. Coronary arteries were perfusion-fixed, serially ...
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  Mentions: Imperial College London Royal Brompton Hospital Aarhus University
11. Detection of early changes in the coronary artery microstructure after heart transplantation: A prospective optical coherence tomography study
  
  Explore ScienceDirect Oct 28 2017 Cardiology
  
  Objectives To describe and characterize changes in the coronary artery microstructure during the first year following heart transplantation (HTx) by serial optical coherence tomography (OCT) scans. Background OCT enables in-vivo cardiac allograft vasculopathy (CAV) microstructure characterization. Early coronary artery microstructure changes after HTx may provide important mechanistic information regarding CAV development. Methods Twenty-six patients were enrolled at routine baseline coronary angiography 3 months after HTx. Coronary OCT scans were performed ...
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  Mentions: Leiden University Aarhus University
12. Serial Assessment of Tissue Precursors and Progression of Coronary Calcification Analyzed by Fusion of IVUS and OCT
  
  Explore ScienceDirect Oct 3 2017 Cardiology
  
  Objectives The aim of this study was to assess calcium growth with fused grayscale intravascular ultrasound (IVUS), IVUSvirtual histology, and optical coherence tomography (OCT) from baseline to 5-year follow-up in patients treated with bioresorbable vascular scaffolds. Background IVUS and OCT have individual strengths in assessing plaque composition and volume. Fusion of images obtained using these methods could potentially aid in coronary plaque assessment. Methods Anatomic landmarks and endoluminal radiopaque markers ...
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  Mentions: Imperial College London Leiden University Capital Medical University
13. Effect of Post-Dilatation Following Primary PCI With Everolimus-Eluting Bioresorbable Scaffold Versus Everolimus-Eluting Metallic Stent Implantation: An Angiographic and Optical Coherence Tomography TROFI II Substudy
  
  Explore ScienceDirect Sep 24 2017 Cardiology
  
  Objectives This study sought to investigate the effect of post-dilatation on angiographic and intracoronary imaging parameters in the setting of primary percutaneous coronary intervention comparing the everolimus-eluting bioresorbable scaffold (BRS) with the everolimus-eluting metallic stent (EES). Background Routine post-dilatation of BRS has been suggested to improve post-procedural angiographic and subsequent device-related clinical outcomes. Methods In the ABSORB STEMI TROFI II trial, 191 patients with ST-segment elevation myocardial infarction were randomly ...
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  Mentions: Academic Medical Center at the University of Amsterdam University of Bern Erasmus University
14. Layered Fibrotic Plaques Are the Predominant Component in Cardiac Allograft Vasculopathy
  
  Explore ScienceDirect Jul 4 2017 Cardiology
  
  Objectives The aims of this study were to characterize cardiac allograft vasculopathy (CAV) phenotypes using optical coherence tomography (OCT) and to evaluate the prognostic significance of OCT-determined CAV severity. Background Intravascular OCT enables in vivo characterization of CAV microstructure after heart transplantation. Methods Sixty-two patients undergoing heart transplantation were enrolled at routine angiography from September 2013 through October 2015 and prospectively followed until censoring on May 27, 2016. Optical coherence ...
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  Mentions: Aarhus University
15. ST Elevation Infarction after Heart Transplantation Induced by Coronary Spasms and Mural Thrombus Detected by Optical Coherence Tomography
  
  Explore Hindawi Publishing Corporation Nov 24 2016 Cardiology
  
  The case illustrates the possible link between coronary spasms, intraluminal thrombus formation, and widespread organized and layered thrombi in HTx patients. Furthermore, the case underlines the clinical value of OCT as a novel method for high-resolution vessel imaging in heart-transplanted (HTx) patients with coronary spasms and suspected coronary artery disease. Coronary spasms and sudden death are frequent complications after HTx. The underlying mechanisms leading to these complications are unknown. The ...
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  Mentions: Aarhus University
16. Serial Multimodality Imaging and 2-Year Clinical Outcomes of the Novel DESolve Novolimus-Eluting Bioresorbable Coronary Scaffold System for the Treatment of Single De Novo Coronary Lesions
  
  Explore Elsevier Mar 26 2016 Cardiology
  
  Objectives This study sought to report the late multimodality imaging and clinical outcomes of the novel poly- l -lactic-acidbased DESolve novolimus-eluting bioresorbable coronary scaffold for the treatment of de novo coronary lesions. Background Bioresorbable scaffolds are an alternative to drug-eluting metallic stents and provide temporary vascular scaffolding, which potentially may allow vessel restoration and reduce the risk of future adverse events. Methods Overall, 126 patients were enrolled at 13 international ...
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  Mentions: Aarhus University
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