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    1. Mentioned In 32 Articles

    2. Rational and Design of the European Randomized Optical Coherence Tomography Optimized Bifurcation Event Reduction Trial (OCTOBER)

      Explore ScienceDirect Cardiology
      Rational and Design of the European Randomized Optical Coherence Tomography Optimized Bifurcation Event Reduction Trial (OCTOBER)
      Background Percutaneous coronary intervention (PCI) in complex bifurcation lesions is prone to suboptimal implantation results and is associated with increased risk of subsequent clinical events. Angiographic ambiguity is high during bifurcation stenting but it is unknown if procedural guidance by intravascular optical coherence tomography (OCT) improves clinical outcome. Methods and design OCTOBER is a randomized, investigator initiated, multi-center trial aimed to show superiority of OCT guided stent implantation compared to ...
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      Mentions: Tampere University of Technology VU University Amsterdam John A. Ormiston

    3. Plaque Burden Influences Accurate Classification of Fibrous Cap Atheroma by In-Vivo Optical Coherence Tomography in a Porcine Model of Advanced Coronary Atherosclerosis

      Explore eurointervention.org Cardiology
      Plaque Burden Influences Accurate Classification of Fibrous Cap Atheroma by In-Vivo Optical Coherence Tomography in a Porcine Model of Advanced Coronary Atherosclerosis
      Aims: In-vivo validation of coronary optical coherence tomography (OCT) against histology and the effects of plaque burden (PB) on plaque classification remain unreported. We investigated this in a porcine model with human-like coronary atherosclerosis. Methods and results: Five female Yucatan D374Y-PCSK9 transgenic hypercholesterolemic mini-pigs were implanted with a coronary shear-modifying stent to induce advanced atherosclerosis. OCT frames (n=201) were obtained 34 weeks after implantation. Coronary arteries were perfusion-fixed, serially ...
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      Mentions: Imperial College London Royal Brompton Hospital Aarhus University

    4. Detection of early changes in the coronary artery microstructure after heart transplantation: A prospective optical coherence tomography study

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      Detection of early changes in the coronary artery microstructure after heart transplantation: A prospective optical coherence tomography study
      Objectives To describe and characterize changes in the coronary artery microstructure during the first year following heart transplantation (HTx) by serial optical coherence tomography (OCT) scans. Background OCT enables in-vivo cardiac allograft vasculopathy (CAV) microstructure characterization. Early coronary artery microstructure changes after HTx may provide important mechanistic information regarding CAV development. Methods Twenty-six patients were enrolled at routine baseline coronary angiography 3 months after HTx. Coronary OCT scans were performed ...
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      Mentions: Leiden University Aarhus University

    5. Serial Assessment of Tissue Precursors and Progression of Coronary Calcification Analyzed by Fusion of IVUS and OCT

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      Serial Assessment of Tissue Precursors and Progression of Coronary Calcification Analyzed by Fusion of IVUS and OCT
      Objectives The aim of this study was to assess calcium growth with fused grayscale intravascular ultrasound (IVUS), IVUSvirtual histology, and optical coherence tomography (OCT) from baseline to 5-year follow-up in patients treated with bioresorbable vascular scaffolds. Background IVUS and OCT have individual strengths in assessing plaque composition and volume. Fusion of images obtained using these methods could potentially aid in coronary plaque assessment. Methods Anatomic landmarks and endoluminal radiopaque markers ...
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      Mentions: Imperial College London Leiden University Capital Medical University

    6. Effect of Post-Dilatation Following Primary PCI With Everolimus-Eluting Bioresorbable Scaffold Versus Everolimus-Eluting Metallic Stent Implantation: An Angiographic and Optical Coherence Tomography TROFI II Substudy

      Explore ScienceDirect Cardiology
      Effect of Post-Dilatation Following Primary PCI With Everolimus-Eluting Bioresorbable Scaffold Versus Everolimus-Eluting Metallic Stent Implantation: An Angiographic and Optical Coherence Tomography TROFI II Substudy
      Objectives This study sought to investigate the effect of post-dilatation on angiographic and intracoronary imaging parameters in the setting of primary percutaneous coronary intervention comparing the everolimus-eluting bioresorbable scaffold (BRS) with the everolimus-eluting metallic stent (EES). Background Routine post-dilatation of BRS has been suggested to improve post-procedural angiographic and subsequent device-related clinical outcomes. Methods In the ABSORB STEMI TROFI II trial, 191 patients with ST-segment elevation myocardial infarction were randomly ...
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      Mentions: Academic Medical Center at the University of Amsterdam Patrick W. Serruys Stephan Windecker

    7. Layered Fibrotic Plaques Are the Predominant Component in Cardiac Allograft Vasculopathy

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      Layered Fibrotic Plaques Are the Predominant Component in Cardiac Allograft Vasculopathy
      Objectives The aims of this study were to characterize cardiac allograft vasculopathy (CAV) phenotypes using optical coherence tomography (OCT) and to evaluate the prognostic significance of OCT-determined CAV severity. Background Intravascular OCT enables in vivo characterization of CAV microstructure after heart transplantation. Methods Sixty-two patients undergoing heart transplantation were enrolled at routine angiography from September 2013 through October 2015 and prospectively followed until censoring on May 27, 2016. Optical coherence ...
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      Mentions: Aarhus University Jouke Dijkstra

    8. ST Elevation Infarction after Heart Transplantation Induced by Coronary Spasms and Mural Thrombus Detected by Optical Coherence Tomography

      Explore Hindawi Publishing Corporation Cardiology
      ST Elevation Infarction after Heart Transplantation Induced by Coronary Spasms and Mural Thrombus Detected by Optical Coherence Tomography
      The case illustrates the possible link between coronary spasms, intraluminal thrombus formation, and widespread organized and layered thrombi in HTx patients. Furthermore, the case underlines the clinical value of OCT as a novel method for high-resolution vessel imaging in heart-transplanted (HTx) patients with coronary spasms and suspected coronary artery disease. Coronary spasms and sudden death are frequent complications after HTx. The underlying mechanisms leading to these complications are unknown. The ...
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      Mentions: Aarhus University

    9. Serial Multimodality Imaging and 2-Year Clinical Outcomes of the Novel DESolve Novolimus-Eluting Bioresorbable Coronary Scaffold System for the Treatment of Single De Novo Coronary Lesions

      Explore Elsevier Cardiology
      Serial Multimodality Imaging and 2-Year Clinical Outcomes of the Novel DESolve Novolimus-Eluting Bioresorbable Coronary Scaffold System for the Treatment of Single De Novo Coronary Lesions
      Objectives This study sought to report the late multimodality imaging and clinical outcomes of the novel poly- l -lactic-acidbased DESolve novolimus-eluting bioresorbable coronary scaffold for the treatment of de novo coronary lesions. Background Bioresorbable scaffolds are an alternative to drug-eluting metallic stents and provide temporary vascular scaffolding, which potentially may allow vessel restoration and reduce the risk of future adverse events. Methods Overall, 126 patients were enrolled at 13 international ...
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      Mentions: John A. Ormiston Aarhus University

    10. Stent collapse after guide extension catheter collision. Signature procedural finding by optical coherence tomography

      Explore International Journal of Cardiology Cardiology
      Stent collapse after guide extension catheter collision. Signature procedural finding by optical coherence tomography
      Excessive deformation of stents can lead to strut fracture and subsequent stent collapse. Procedural damages to the stent are rarely visible by angiography during implantation but may be detected by OCT. Here we present a case with a subtle but signature finding by OCT indicative of stent fracture.
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      Mentions: Aarhus University

    11. Impact of Side Branch Modeling on Computation of Endothelial Shear Stress in Coronary Artery Disease Coronary Tree Reconstruction by Fusion of 3D Angiography and OCT

      Explore JACC Cardiology
      Impact of Side Branch Modeling on Computation of Endothelial Shear Stress in Coronary Artery Disease Coronary Tree Reconstruction by Fusion of 3D Angiography and OCT
      Background Computational fluid dynamics allow virtual evaluation of coronary physiology and shear stress (SS). Most studies hitherto assumed the vessel as a single conduit without accounting for the flow through side branches. Objectives This study sought to develop a new approach to reconstruct coronary geometry that also computes outgoing flow through side branches in hemodynamic and biomechanical calculations, using fusion of optical coherence tomography (OCT) and 3-dimensional (3D) angiography. Methods ...
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      Mentions: Leiden University Shanghai Jiao Tong University Aarhus University

    12. OCT for bifurcation stenting: what have we learned?

      Explore eurointervention.org Cardiology
      OCT for bifurcation stenting: what have we learned?
      Treatment of bifurcation lesions by percutaneous coronary intervention (PCI) shows major variation in complexity. Intravascular optical coherence tomography (OCT) provides high-resolution images of the pathoanatomy, thrombus, wires and stent positions during the procedure. This information may prove crucial in optimising PCI results and clinical outcomes after complex bifurcation treatment. Mounting evidence confirms the feasibility of OCT in bifurcations, and specific steps where OCT may be advantageous in guiding bifurcation PCI ...
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      Mentions: Leiden University Toshiro Shinke Kobe University Graduate School of Medicine

    14. In search for the Holy Grail: Suggestions for studies to define delta changes to diagnose or exclude acute myocardial infarction: a position paper from the study group on biomarkers of the Acute Cardiovascular Care Association

      Explore European Heart Journal Cardiology
      In search for the Holy Grail: Suggestions for studies to define delta changes to diagnose or exclude acute myocardial infarction: a position paper from the study group on biomarkers of the Acute Cardiovascular Care Association
      ... ^7Department of Laboratory Medicine, University Hospital, Padova, Italy 8. ^8Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark 9. ^9Department of Medical Sciences, Uppsala University and Up...
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      Mentions: University of Heidelberg Uppsala University Aarhus University

    15. Serial optical frequency domain imaging in STEMI patients: the follow-up report of TROFI study

      Explore ehjcimaging.oxfordjournals.org Cardiology
      Serial optical frequency domain imaging in STEMI patients: the follow-up report of TROFI study
      Aims To investigate the incidence of incomplete stent apposition and to explore the impact of the presence of thrombus and protruding plaque after stent implantation on neointima formation at follow-up in ST-segment elevation myocardial infarction (STEMI) patients with serial optical frequency domain imaging (OFDI) investigations. Methods and results In a multi-centre study, 141 patients with ST elevation myocardial infarction 12 h from onset were randomized to either PPCI with thrombectomy ...
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      Mentions: Terumo Corporation Patrick W. Serruys Hector M. Garcia-Garcia
    17. 1-15 of 32 1 2 »
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  4. About Aarhus University

    Aarhus University is a public university located in Aarhus, Denmark. Founded in 1928, it is Denmark's second oldest university with a total of 43,600 enrolled students as of 1 Jan 2012 after a merger with Aarhus School of Engineering.

     

    Aarhus University Hospital which comprises hospitals in Århus providing national and regional specialist services. The University Hospital includes Århus Kommunehospital, Århus Amtssygehus, Skejby Sygehus and Psykiatrisk Hospital (Århus County Hospital, Skejby Hospital and the Psychiatric Hospital in Århus, respectively) as well as the Faculty of Health Sciences at the University of Aarhus. Together the four university teaching hospitals cover all areas of medical and surgical specialist care, supplementing each other on a daily basis as collaborating specialists.

  5. Related Topics

    1. A bioabsorbable everolimus-eluting coronary stent system (ABSORB): 2-year outcomes and results from multiple imaging methods
      13 articles also mentioned Erasmus University