1. Articles mentioning both Zhongping Chen and UC Irvine

    1-24 of 228 1 2 3 4 5 6 7 8 9 10 »
    1. UC Irvine Receives a 2020 NIH Grant for In Vivo Imaging and Quantification of Cilia Beating Dynamics Using Phase-Resolved Optical Imaging Technology

      UC Irvine Receives a 2020 NIH Grant for In Vivo Imaging and Quantification of Cilia Beating Dynamics Using Phase-Resolved Optical Imaging Technology
      ...tion of Cilia Beating Dynamics Using Phase-Resolved Optical Imaging Technology. The principal investigator is Zhongping Chen. Below is a summary of the proposed work.

      Each year, 50M Am...

      Read Full Article
    2. UC Irvine Receives a 2020 NIH Grant for Phased Resolved ARF Optical Coherence Elastography for Intravascular Imaging

      UC Irvine Receives a 2020 NIH Grant for Phased Resolved ARF Optical Coherence Elastography for Intravascular Imaging
      ...r Phased Resolved ARF Optical Coherence Elastography for Intravascular Imaging. The principal investigator is Zhongping Chen. Below is a summary of the proposed work. Cardiovascular disease is responsible for 1 in 4 dea...
      Read Full Article
    3. Ultrahigh-sensitive optical coherence elastography

      Ultrahigh-sensitive optical coherence elastography
      The phase stability of an optical coherence elastography (OCE) system is the key determining factor for achieving a precise elasticity measurement, and it can be affected by the signal-to-noise ratio (SNR), timing jitters in the signal acquisition process, and fluctuations in the optical path difference (OPD) between the sample and reference arms. In this study, we developed an OCE system based on swept-source optical coherence tomography (SS-OCT) with a common-path ...
      Read Full Article
    4. Optical Vaginal Biopsy Using Optical Coherence Tomography

      Optical Vaginal Biopsy Using Optical Coherence Tomography
      Objective Optical coherence tomography is a noninvasive technology that visualizes tissue microstructure with high spatial resolution. We designed a novel vaginal system that demonstrates a clear distinction between vaginal tissues planes. In this study, we sought to compare vaginal tomographic images of premenopausal, perimenopausal, and postmenopausal women, demonstrate feasibility of tracking vaginal tissue changes after treatment with fractional-pixel CO 2 laser therapy, and obtain a histologic correlation of these findings ...
      Read Full Article
    5. Extended imaging depth of en-face optical coherence tomography based on fast measurement of a reflection matrix by wide-field heterodyne detection

      Extended imaging depth of en-face optical coherence tomography based on fast measurement of a reflection matrix by wide-field heterodyne detection
      Multiple light scattering in biomedical tissue limits the penetration depth of optical imaging systems such as optical coherence tomography. To increase the imaging depth in scattering media, a computational method based on coherent reflection matrix measurement has been developed using low coherence interferometry. The complex reflection matrix is obtained via point-by-point scanning followed by a phase-shifting method; then singular value decomposition is used to retrieve the singly back-scattered light. However ...
      Read Full Article
    6. Optical coherence elastography (OCE) method under acoustic radiation force excitation using OCT doppler variance methods and OCT correlation-based methods

      Optical coherence elastography (OCE) method under acoustic radiation force excitation using OCT doppler variance methods and OCT correlation-based methods
      A system for imaging and quantifying shear wave and shear modulus under orthogonal acoustic radiation force (ARF) excitation using the OCT Doppler variance apparatus. The ARF perpendicular or with at least a perpendicular component to the OCT beam is produced by a remote ultrasonic transducer. The OCT Doppler variance apparatus, which is sensitive to the transverse vibration, is used to measure the ARF induced vibration. For analysis of the shear ...
      Read Full Article
    7. In vivo evaluation of posterior eye elasticity using shaker-based optical coherence elastography

      In vivo evaluation of posterior eye elasticity using shaker-based optical coherence elastography
      Age-related macular degeneration (AMD) is a progressive retinal disease and becomes the leading cause of blindness. It is well established that early detection is the key to preservation of functional vision. However, it is very difficult to diagnose AMD in very early stages, before structural changes are evident. Consequently, investigating the biomechanical properties of the retina maybe essential for understanding its physiological function. In this study, we present a shear ...
      Read Full Article
    8. Spatiotemporal dynamics of pial collateral blood flow following permanent middle cerebral artery occlusion in a rat model of sensory-based protection: a Doppler optical coherence tomography study

      Spatiotemporal dynamics of pial collateral blood flow following permanent middle cerebral artery occlusion in a rat model of sensory-based protection: a Doppler optical coherence tomography study
      There is a growing recognition regarding the importance of pial collateral flow in the protection from impending ischemic stroke both in preclinical and clinical studies. Collateral flow is also a major player in sensory stimulation-based protection from impending ischemic stroke. Doppler optical coherence tomography has been employed to image spatiotemporal patterns of collateral flow within the dorsal branches of the middle cerebral artery (MCA) as it provides a powerful tool ...
      Read Full Article
    9. The Use of Optical Coherence Tomography and Convolutional Neural Networks to Distinguish Normal and Abnormal Oral Mucosa

      The Use of Optical Coherence Tomography and Convolutional Neural Networks to Distinguish Normal and Abnormal Oral Mucosa
      Incomplete surgical resection of head and neck squamous cell carcinoma (HNSCC) is the most common cause of local HNSCC recurrence. Currently, surgeons rely on pre‐operative imaging, direct visualization, palpation, and frozen section to determine the extent of tissue resection. It has been demonstrated that optical coherence tomography (OCT), a minimally invasive, non‐ionizing near infrared mesoscopic imaging modality can resolve subsurface differences between normal and abnormal head and neck ...
      Read Full Article
    10. Automatic three-dimensional segmentation method for OCT and doppler OCT angiography

      Automatic three-dimensional segmentation method for OCT and doppler OCT angiography
      A three-dimensional (three dimensional) segmentation method with intensity-based Doppler variance (IBDV) based on swept-source OCT. The automatic three dimensional segmentation method is used to obtain seven surfaces of intra-retinal layers. The microvascular network of the retina, which is acquired by the IBDV method, can be divided into six layers. The microvascular network of the six individual layers are visualized, and the morphology and contrast images can be improved by using ...
      Read Full Article
    11. Method to characterize cut gemstones using optical coherence tomography

      Method to characterize cut gemstones using optical coherence tomography
      The invention includes an improvement in a method of assessing a gemstone having at least one planar face with an internally reflecting surface including the steps of optically modifying the at least one planar face of the gemstone to return a sample beam from an internally reflecting plane corresponding to the at least one planar face to an optical coherence tomography (OCT) system; selectively directing the sample beam from an ...
      Read Full Article
    12. Acoustic Radiation Force Optical Coherence Elastography

      Acoustic Radiation Force Optical Coherence Elastography
      Mechanical properties, such as the elasticity and viscosity, are often major indicators of diseases. Over the years, tissue mechanical properties have been demonstrated to be an early indicator for cardiovascular disease. Mechanical imaging technologies have been quickly evolving with a goal to effectively diagnose coronary artery disease and atherosclerosis in their early stages. By combining the advantages of acoustic and optical properties, acoustic radiation force optical coherence elastography (ARF-OCE) has ...
      Read Full Article
    13. Endoscopic Optical Coherence Tomography for Assessing Inhalation Airway Injury: A Technical Review

      Endoscopic Optical Coherence Tomography for Assessing Inhalation Airway Injury: A Technical Review
      Diagnosis of inhalation injury has been clinically challenging. Currently, assessment of inhalation injury relies on subjective clinical exams and bronchoscopy, which provides little understanding of tissue conditions and results in limited prognostics. Endoscopic Optical coherence tomography (OCT) technology has been recently utilized in the airway for direct assessment of respiratory tract disorders and injuries. Endoscopic OCT is capable of capturing highresolution images of tissue morphology 1-3 mm beneath the surface ...
      Read Full Article
    14. Dynamic programming and automated segmentation of optical coherence tomography images of the neonatal subglottis: enabling efficient diagnostics to manage subglottic stenosis

      Dynamic programming and automated segmentation of optical coherence tomography images of the neonatal subglottis: enabling efficient diagnostics to manage subglottic stenosis
      Subglottic stenosis (SGS) is a challenging disease to diagnose in neonates. Long-range optical coherence tomography (OCT) is an optical imaging modality that has been described to image the subglottis in intubated neonates. A major challenge associated with OCT imaging is the lack of an automated method for image analysis and micrometry of large volumes of data that are acquired with each airway scan (1 to 2 Gb). We developed a ...
      Read Full Article
    15. Assessment of blood coagulation using an acoustic radiation force based optical coherence elastography (ARF-OCE)

      Assessment of blood coagulation using an acoustic radiation force based optical coherence elastography (ARF-OCE)
      An apparatus and method of using an optical coherence elastography (OCE) under acoustic radiation force (ARF) excitation includes the steps of inducing an excitation wave in a blood sample by use of an ultrasound beam from an ultrasonic transducer; measuring an elastic property of the blood sample by use of an optical coherence tomography (OCT) beam transverse to the ultrasound beam to dynamically measure the elastic property of the blood ...
      Read Full Article
    16. Fiber-based polarization-sensitive optical coherence tomography of a minimalistic system configuration

      Fiber-based polarization-sensitive optical coherence tomography of a minimalistic system configuration
      We present a very simple method of constructing a polarization-sensitive optical coherence tomography (PS-OCT) system. An ordinary fiber-based swept-source OCT system was reconfigured for PS-OCT by adding a long section of polarization-maintaining fiber in the sample arm. Two polarization modes of a large group-delay difference formed spatially distinguished polarization channels. The depth-encoded information on the polarization states was retrieved by an amplitude-based analysis. We found that our method provides an ...
      Read Full Article
    17. Multimodal endoscopy for colorectal cancer detection by optical coherence tomography and near-infrared fluorescence imaging

      Multimodal endoscopy for colorectal cancer detection by optical coherence tomography and near-infrared fluorescence imaging
      While colonoscopy is the gold standard for diagnosis and classification of colorectal cancer (CRC), its sensitivity and specificity are operator-dependent and are especially poor for small and flat lesions. Contemporary imaging modalities, such as optical coherence tomography (OCT) and near-infrared (NIR) fluorescence, have been investigated to visualize microvasculature and morphological changes for detecting early stage CRC in the gastrointestinal (GI) tract. In our study, we developed a multimodal endoscopic system ...
      Read Full Article
    18. Automatic Proximal Airway Volume Segmentation Using Optical Coherence Tomography for Assessment of Inhalation Injury

      Automatic Proximal Airway Volume Segmentation Using Optical Coherence Tomography for Assessment of Inhalation Injury
      Background Acute respiratory distress syndrome (ARDS) is a severe form of acute lung injury with a mortality rate of up to 40%. Early management of ARDS has been difficult due to the lack of sensitive imaging tools and robust analysis software. We previously designed an optical coherence tomography (OCT) system to evaluate mucosa thickness (MT) post smoke inhalation, but the analysis relied on manual segmentation. The aim of this study ...
      Read Full Article
    19. The effect of melanin on in vivo optical coherence tomography of the skin in a multiethnic cohort

      The effect of melanin on in vivo optical coherence tomography of the skin in a multiethnic cohort
      Background Noninvasive real‐time assessment of living tissue is quickly becoming invaluable for bolstering histologic and dermatoscopic measures of cutaneous conditions. While many skin researchers have explored the utility of noninvasive imaging in inflammatory and malignant skin conditions, there is yet to be a definitive and direct assessment of the effects of melanin on the quality of optical coherence tomography (OCT) imaging and its accuracy in multiethnic patient populations. We ...
      Read Full Article
    20. Intra-operative point-of-procedure delineation of oral cancer margins using optical coherence tomography

      Intra-operative point-of-procedure delineation of oral cancer margins using optical coherence tomography
      Objectives Surgical margin status is a significant determinant of treatment outcome in oral cancer. Negative surgical margins can decrease the loco-regional recurrence by five-fold. The current standard of care of intraoperative clinical examination supplemented by histological frozen section, can result in a risk of positive margins from 5 to 17 percent. In this study, we attempted to assess the utility of intraoperative optical coherence tomography (OCT) imaging with automated diagnostic ...
      Read Full Article
    21. Integrated ultrasound, OCT, PA and/or florescence imaging endoscope for diagnosing cancers in gastrointestinal, respiratory, and urogenital tracts

      Integrated ultrasound, OCT, PA and/or florescence imaging endoscope for diagnosing cancers in gastrointestinal, respiratory, and urogenital tracts
      A multimodality imaging system including ultrasound, optical coherence tomography (OCT), photoacoustic (PA) imaging, florescence imaging and endoscopic catheter for imaging inside the gastrointestinal tract with real-time automatic image co-registration capability, including: an ultrasound subsystem for imaging; an optical coherence tomography (OCT) subsystem for imaging, a PA microscopy or tomography subsystem for imaging and a florescence imaging subsystem for imaging. An invasive interventional imaging device is included with an instrumentality to ...
      Read Full Article
    22. Perspective: Current challenges and solutions of Doppler optical coherence tomography and angiography for neuroimaging

      Perspective: Current challenges and solutions of Doppler optical coherence tomography and angiography for neuroimaging
      The nervous system, based on a complex network of nerves and cells, carries messages by transmitting signals to and from different parts of the body. The supply of blood flow in the nervous system is critical to maintain physiological functions. Optical coherence tomography (OCT) has the ability to noninvasively image the microvascular networks and accurately quantify the blood flow in vivo with high spatial and temporal resolutions in three dimensions ...
      Read Full Article
    23. Point-of-care endoscopic optical coherence tomography detects changes in mucosal thickness in ARDS due to smoke inhalation and burns

      Point-of-care endoscopic optical coherence tomography detects changes in mucosal thickness in ARDS due to smoke inhalation and burns
      Background The prevalence of acute respiratory distress syndrome (ARDS) in mechanically ventilated burn patients is 33%, with mortality varying from 1146% depending on ARDS severity. Despite the new Berlin definition for ARDS, prompt bedside diagnosis is lacking. We developed and tested a bedside technique of fiberoptic-bronchoscopy-based optical coherence tomography (OCT) measurement of airway mucosal thickness (MT) for diagnosis of ARDS following smoke inhalation injury (SII) and burns. Methods 16 female ...
      Read Full Article
    24. Phase-stability optimization of swept-source optical coherence tomography

      Phase-stability optimization of swept-source optical coherence tomography
      Phase-resolved imaging of swept-source optical coherence tomography (SS-OCT) is subject to phase measurement instabilities involved with the sweep variation of a frequency-swept source. In general, optically generated timing references are utilized to track the variations imposed on OCT signals. But they might not be accurately synchronized due to relative time delays. In this research, we investigated the impact of the signal delays on the timing instabilities and the consequent deviations ...
      Read Full Article
    25. 1-24 of 228 1 2 3 4 5 6 7 8 9 10 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Organizations in the News

    1. (22 articles) University of Southern California
    2. (17 articles) National Institutes of Health
    3. (5 articles) UCLA
    4. (3 articles) Ludwig Maximilian University of Munich
    5. (3 articles) Gwangju Institute of Science and Technology
    6. (3 articles) Pusan National University
    7. (2 articles) Vanderbilt University
    8. (2 articles) Washington University in St. Louis
    9. (2 articles) Massachusetts General Hospital
    10. (2 articles) Wenzhou Medical College
    11. (2 articles) California Institute of Technology
    12. (2 articles) Zhejiang University
  3. People in the News

    1. (46 articles) Brian J. F. Wong
    2. (33 articles) Gangjun Liu
    3. (29 articles) Jun Zhang
    4. (26 articles) Joseph C. Jing
    5. (25 articles) Qifa Zhou
    6. (25 articles) Lingfeng Yu
    7. (24 articles) Matthew Brenner
    8. (21 articles) Jiang Zhu
    9. (21 articles) K. Kirk Shung
    10. (13 articles) Petra E. Wilder-Smith
    11. (13 articles) Shuguang Guo
    12. (11 articles) J. Stuart Nelson
  4. OCT Companies in the News

    1. (7 articles) OCT Medical Imaging Inc
    2. (4 articles) Imalux
    3. (3 articles) Axsun Technologies
    4. (2 articles) Terumo Corporation
    5. (2 articles) Abbot
    6. (1 articles) Lantis Laser
    7. (1 articles) Diagnostic Photonics
    8. (1 articles) LLTech
    9. (1 articles) Tomophase Corporation
    10. (1 articles) Boston Scientific
    11. (1 articles) Heliotis AG
    12. (1 articles) Cordis