1. Articles mentioning both University of Washington and Ruikang K. Wang

    1-24 of 230 1 2 3 4 5 6 7 8 9 10 »
    1. Correlations Between Choriocapillaris Flow Deficits Around Geographic Atrophy and Enlargement Rates Based on Swept Source OCT Imaging

      Correlations Between Choriocapillaris Flow Deficits Around Geographic Atrophy and Enlargement Rates Based on Swept Source OCT Imaging
      Purpose To determine the possible correlation between the annual enlargement rates (ERs) of geographic atrophy (GA) with the percentage and size of the choriocapillaris (CC) flow deficits (FDs) surrounding GA, measured with swept source optical coherence tomography angiography (SS-OCTA) images. Design Prospective, observational case series. Participants Patients with GA secondary to non-exudative AMD. Methods Patients were imaged with a 100-kHz SS-OCTA instrument (PLEX Elite 9000, Carl Zeiss Meditec) using a ...
      Read Full Article
    2. Monitoring acute stroke progression: multi-parametric OCT imaging of cortical perfusion, flow, and tissue scattering in a mouse model of permanent focal ischemia

      Monitoring acute stroke progression: multi-parametric OCT imaging of cortical perfusion, flow, and tissue scattering in a mouse model of permanent focal ischemia
      Cerebral ischemic stroke causes injury to brain tissue characterized by a complex cascade of neuronal and vascular events. Imaging during early stages of its development allows prediction of tissue infarction and penumbra, so that optimal intervention can be determined in order to salvage brain function impairment. Therefore, there is a critical need for novel imaging techniques that can characterize brain injury in the earliest phases of ischemic stroke. This study ...
      Read Full Article
    3. Microvascular imaging of the skin

      Microvascular imaging of the skin
      Despite our understanding that the microvasculature plays a multifaceted role in the development and progression of various conditions, we know little about the extent of this involvement. A need exists for non-invasive, clinically meaningful imaging modalities capable of elucidating microvascular information to aid in our understanding of disease, and to aid in the diagnosis/monitoring of disease for more patient-specific care. In this review article, a number of imaging techniques ...
      Read Full Article
    4. Age-Dependent Changes in the Macular Choriocapillaris of Normal Eyes Imaged with Swept-Source OCT Angiography

      Age-Dependent Changes in the Macular Choriocapillaris of Normal Eyes Imaged with Swept-Source OCT Angiography
      Purpose Swept source optical coherence tomography angiography (SS-OCTA) was used to measure the age-dependent changes in macular choriocapillaris (CC) flow deficits (FDs) in normal eyes. Design A prospective, cross-sectional study. Methods Subjects with normal eyes ranging in age from their 20s to their 80s were imaged using a 100-kHz SS-OCTA instrument (PLEX Elite 9000, Carl Zeiss Meditec). Both 3x3 mm and 6x6 mm scans were used to image the macular ...
      Read Full Article
    5. Diagnostic Performance of Macular Versus Peripapillary Vessel Parameters by Optical Coherence Tomography Angiography for Glaucoma

      Diagnostic Performance of Macular Versus Peripapillary Vessel Parameters by Optical Coherence Tomography Angiography for Glaucoma
      Purpose : To compare the diagnostic ability of the vessel parameters in macular and peripapillary regions measured using spectral-domain optical coherence tomography angiography (SD-OCTA) in differentiating primary open-angle glaucoma (POAG) from healthy eyes. Methods : POAG patients and healthy subjects underwent 6 6-mm scans centered on the macula and optic nerve head. Commercially available automatic segmentation created en face images from SD-OCTA of the superficial retinal layer (SRL) of the macular (m ...
      Read Full Article
    6. Imaging and visualization of the polarization state of the probing beam in polarization-sensitive optical coherence tomography

      Imaging and visualization of the polarization state of the probing beam in polarization-sensitive optical coherence tomography
      We propose a simple and efficient method of color-encoded Stokes parameters to visualize the polarization states for polarization-sensitive optical coherence tomography (PS-OCT) of biological tissue. In this method, polarization states of the probing light are detected and described in the Stokes domain. Three primary colors of red, green, and blue are used to code Stokes parameters of Q, U, and V, respectively, which can be used to represent and visualize ...
      Read Full Article
    7. Attenuation correction assisted automatic segmentation for assessing choroidal thickness and vasculature with swept-source OCT

      Attenuation correction assisted automatic segmentation for assessing choroidal thickness and vasculature with swept-source OCT
      ...ries,” Am. J. Ophthalmol. 169, 104–112 (2016). [Crossref] [PubMed] U. Baran, W. Qin, X. L. Qi, G. Kalkan, and R. K. Wang, “OCT-based label-free in vivo lymphangiography within human skin and areola,” Sci. Rep. 6, 21122 (...
      Read Full Article
    8. Peripapillary microvasculature in the retinal nerve fiber layer in glaucoma by optical coherence tomography angiography: focal structural and functional correlations and diagnostic performance

      Peripapillary microvasculature in the retinal nerve fiber layer in glaucoma by optical coherence tomography angiography: focal structural and functional correlations and diagnostic performance
      ...School of Medicine of University of Southern California, Los Angeles, CA, USA; 2Department of Bioengineering, University of Washington, Seattle, WA, USA *These authors contributed equally to this work Purpose: To quantif...
      Read Full Article
    9. Ultra-wide optical coherence tomography angiography in diabetic retinopathy

      Ultra-wide optical coherence tomography angiography in diabetic retinopathy
      Background: To implement an ultra-wide optical coherence tomography angiography imaging (UW-OCTA) modality in eyes with diabetic retinopathy (DR) with the aim of quantifying the burden of microvascular disease at baseline and subsequent clinic visits. Methods: UW-OCTA was implemented on a 1,060 nm swept source (SS) OCTA engine running at 100 kHz A-line rate with a motion tracking mechanism. A montage scanning protocol was used to capture a 100-degree field ...
      Read Full Article
    10. Mapping and Quantitating Penetrating Vessels in Cortical Brain Using Eigen-Decomposition of OCT Signals and Subsequent Principal Component Analysis

      Mapping and Quantitating Penetrating Vessels in Cortical Brain Using Eigen-Decomposition of OCT Signals and Subsequent Principal Component Analysis
      Penetrating vessels bridge the mesh of communicating vessels on the surface of the cortex with the subsurface microvascular beds that feed the underlying neural tissue. Their accurate identification in vivo is important in the investigations of neural degenerative diseases, e.g., Alzheimer's disease and stroke. Here, we propose an efficient method to automatically map cortical penetrating vessels based on an eigen decompensation analysis of the optical coherence tomography (OCT ...
      Read Full Article
    11. Use of En Face Swept-Source Optical Coherence Tomography Angiography in Identifying Choroidal Flow Voids in 3 Patients With Birdshot Chorioretinopathy

      Use of En Face Swept-Source Optical Coherence Tomography Angiography in Identifying Choroidal Flow Voids in 3 Patients With Birdshot Chorioretinopathy
      Importance Patients with birdshot chorioretinopathy (BSCR) can experience a delay in diagnosis owing to the challenges of identifying the condition prior to evolution of characteristic choroidal scars. An objective, noninvasive method for detecting early lesions in BSCR might have an effect on preventing vision loss in these patients. Objective To test the feasibility of swept-source optical coherence tomography angiography (SS-OCTA) in the detection of BSCR choroidal lesions and to use ...
      Read Full Article
    12. A non‐invasive imaging and measurement using optical coherence tomography angiography for the assessment of gingiva: An in vivo study

      A non‐invasive imaging and measurement using optical coherence tomography angiography for the assessment of gingiva: An in vivo study
      Gingiva is the soft tissue that surrounds and protects the teeth. Healthy gingiva provides an effective barrier to periodontal insults to deeper tissue, thus is an important indicator to a patients periodontal health. Current methods in assessing gingival tissue health, including visual observation and physical examination with probing on the gingiva, are qualitative and subjective. They may become cumbersome when more complex cases are involved, such as variations in gingival ...
      Read Full Article
    13. Comparing imaging capabilities of spectral domain and swept source optical coherence tomography angiography in healthy subjects and central serous retinopathy

      Comparing imaging capabilities of spectral domain and swept source optical coherence tomography angiography in healthy subjects and central serous retinopathy
      Background There are two forms of system implementation of optical coherence tomography angiography (OCTA) in ophthalmic imaging, i.e., spectral domain (SD-) and swept source OCTA (SS-OCTA). The purpose of this paper is to compare the SD-OCTA and SS-OCTA for elucidating structural and vascular features associated with central serous retinopathy (CSR), and to evaluate the effects of CSR on SD- and SS-OCTAs imaging capabilities. Methods Normal subjects and CSR patients ...
      Read Full Article
    14. Repeatability and Reproducibility of Quantitative Assessment of the Retinal Microvasculature Using Optical Coherence Tomography Angiography Based on Optical Microangiography

      Repeatability and Reproducibility of Quantitative Assessment of the Retinal Microvasculature Using Optical Coherence Tomography Angiography Based on Optical Microangiography
      Objective The aim of this study was to determine the repeatability and reproducibility of optical coherence tomography angiography (OCTA) based on optical microangiography (OMAG) measurements of macular vessels in normal eyes. Methods In this prospective cohort study, 40 eyes of 40 healthy volunteers underwent repeated OCTA (Cirrus HD-OCT 5000 angiography system, Carl Zeiss Meditec, Inc.) scans on two separate visit days. On each visit day, the eyes were scanned three ...
      Read Full Article
    15. Aging-associated changes in cerebral vasculature and blood flow as determined by quantitative optical coherence tomography angiography

      Aging-associated changes in cerebral vasculature and blood flow as determined by quantitative optical coherence tomography angiography
      Capillary velocity increases by 21% and velocity heterogeneity increases by 19% with older age. Abstract Normal aging is associated with significant alterations in brains vascular structure and function, which can lead to compromised cerebral circulation and increased risk of neurodegeneration. The in vivo examination of cerebral blood flow (CBF), including capillary beds, in aging brains with sufficient spatial detail remains challenging with current imaging modalities. In the present study, we ...
      Read Full Article
    16. Multiple Research Scientist and Post-Doctoral Positions in OCT Available at the University of Washington, Seattle.

      Multiple Research Scientist and Post-Doctoral Positions in OCT Available at the University of Washington, Seattle.
      ...ered. Please send resume and names of 3 references via email to: Ruikang Wang, PhD Professor, Bioengineering, University of Washington wangrk@uw.edu There are multiple research scientists and postdoctoral positions immed...
      Read Full Article
    17. Automated three‐dimensional cell counting method for grading uveitis of rodent eye in vivo with optical coherence tomography

      Automated three‐dimensional cell counting method for grading uveitis of rodent eye in vivo with optical coherence tomography
      In preclinical vision research, cell grading in small animal models is essential for the quantitative evaluation of intraocular inflammation. Here, we present a new and practical optical coherence tomography (OCT) image analysis method for the automated detection and counting of aqueous cells in the anterior chamber (AC) of a rodent model of uveitis. Anterior segment OCT images are acquired with a 100kHz swept‐source OCT system. The proposed method consists ...
      Read Full Article
    18. OCT‐based angiography of human dermal microvascular reactions to local stimuli: Implications for increasing capillary blood collection volumes

      OCT‐based angiography of human dermal microvascular reactions to local stimuli: Implications for increasing capillary blood collection volumes
      Objectives To measure and compare microvascular responses within the skin of the upper arm to local stimuli, such as heating or rubbing, through the use of optical coherence tomography angiography (OCTA), and to investigate its impact on blood volume collection. Materials and Methods With the use of heat packs or rubbing, local stimulation was applied to the skin of either the left or right upper arm. Data from the stimulated ...
      Read Full Article
    19. Optical coherence tomography angiography monitors human cutaneous wound healing over time

      Optical coherence tomography angiography monitors human cutaneous wound healing over time
      Background: In vivo imaging of the complex cascade of events known to be pivotal elements in the healing of cutaneous wounds is a difficult but essential task. Current techniques are highly invasive, or lack the level of vascular and structural detail required for accurate evaluation, monitoring and treatment. We aimed to use an advanced optical coherence tomography (OCT)-based angiography (OCTA) technique for the non-invasive, high resolution imaging of cutaneous ...
      Read Full Article
    20. Generating​ ​retinal​ ​flow​ ​maps​ ​from​ ​structural​ ​optical​ ​coherence​ ​tomography​ ​with​ ​artificial intelligence

      Generating​ ​retinal​ ​flow​ ​maps​ ​from​ ​structural​ ​optical​ ​coherence​ ​tomography​ ​with​ ​artificial intelligence
      Despite advances in artificial intelligence (AI), its application in medical imaging has been burdened and limited by expert-generated labels. We used images from optical coherence tomography angiography (OCTA), a relatively new imaging modality that measures retinal blood flow, to train an AI algorithm to generate flow maps from standard optical coherence tomography (OCT) images, exceeding the ability and bypassing the need for expert labeling. Deep learning was able to infer ...
      Read Full Article
    21. Generating perfusion maps from structural optical coherence tomography with artificial intelligence

      Generating perfusion maps from structural optical coherence tomography with artificial intelligence
      Despite significant advances in artificial intelligence (AI) for computer vision, its application in medical imaging has been limited by the burden and limits of expert-generated labels. We used images from optical coherence tomography angiography (OCTA), a relatively new imaging modality that measures perfusion of the retinal vasculature, to train an AI algorithm to generate vasculature maps from standard structural optical coherence tomography (OCT) images of the same retinae, both exceeding ...
      Read Full Article
    22. Optical coherence tomography angiography and cutaneous wound healing

      Optical coherence tomography angiography and cutaneous wound healing
      Background: Examination of the skins vascular and structural features is essential in clinical, medical, and research dermatology. However, there is a lack of comprehensive imaging tools that clearly and accurately evaluates the skins vascular and structural features. Current techniques are invasive and have inherent preparatory drawbacks. Aim: To use optical coherence tomography angiography (OCTA) for a more accurate depiction of vessels in the skin without the use of a dye ...
      Read Full Article
    23. Optical Coherence Tomography Microangiography Imaging of Circumscribed Choroidal Hemangioma

      Optical Coherence Tomography Microangiography Imaging of Circumscribed Choroidal Hemangioma
      Optical coherence tomography angiography (OCTA) is a new imaging technology capable of providing three-dimensional (3-D) retinal and choroidal microvascular maps without a need for exogenous dye. In this study, the authors evaluate the retinal and choroidal microvascular architecture of the macula in a patient with choroidal hemangioma using OCTA. Widefield OCTA with tracking capability and segmentation was performed to provide images with a field of view at 9 9 mm ...
      Read Full Article
    24. Structural and Functional Associations of Macular Microcirculation in the Ganglion Cell-inner Plexiform Layer in Glaucoma Using Optical Coherence Tomography Angiography

      Structural and Functional Associations of Macular Microcirculation in the Ganglion Cell-inner Plexiform Layer in Glaucoma Using Optical Coherence Tomography Angiography
      Purpose: To quantify retinal microvasculature within the macular ganglion cell-inner plexiform layer (GCIPL) in primary open angle glaucoma (POAG) and normal eyes, determine association of vessel parameters with structural and functional measures, and report diagnostic accuracy of vessel parameters. Methods: POAG and normal patients underwent 6▒mm6▒mm macula scans (Angioplex TM optical coherence tomography angiography [OCTA]; Cirrus TM HD-OCT 5000); and Humphrey Field Analyzer II-i 24-2 visual field (VF ...
      Read Full Article
    25. 1-24 of 230 1 2 3 4 5 6 7 8 9 10 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Organizations in the News

    1. (35 articles) Oregon Health & Science University
    2. (13 articles) University of Miami
    3. (11 articles) National Institutes of Health
    4. (11 articles) University of Dundee
    5. (6 articles) University of Southern California
    6. (4 articles) University of Michigan
    7. (2 articles) National University of Ireland, Galway
    8. (2 articles) University of Wisconsin
    9. (2 articles) FDA
    10. (2 articles) Capital Medical University
    11. (2 articles) University of Western Australia
    12. (1 articles) Northwestern University
  3. People in the News

    1. (25 articles) Woo June Choi
    2. (23 articles) Lin An
    3. (21 articles) Zhongwei Zhi
    4. (17 articles) Alfred L. Nuttall
    5. (16 articles) Roberto Reif
    6. (16 articles) Peng Li
    7. (15 articles) Tueng T. Shen
    8. (12 articles) Philip J. Rosenfeld
    9. (12 articles) Steven L. Jacques
    10. (11 articles) Chunhui Li
    11. (11 articles) Thu-Mai Nguyen
    12. (11 articles) Giovanni Gregori
  4. OCT Companies in the News

    1. (21 articles) Carl Zeiss Meditec
    2. (2 articles) UTC Aerospace Systems
    3. (1 articles) Optovue
    4. (1 articles) Topcon Medical Systems
    5. (1 articles) Optos