1. Articles mentioning both University of Melbourne and Peter Barlis

    1-24 of 35 1 2 »
    1. Clozapine-Induced Myocarditis or Acute Coronary Syndrome? Optical Coherence Tomography to the Rescue

      Clozapine-Induced Myocarditis or Acute Coronary Syndrome? Optical Coherence Tomography to the Rescue
      Chest pain and troponin elevation may be due to an acute coronary syndrome, myocarditis, acute cardiomyopathy, or other less common conditions. Management differs depending on the aetiology, and the pathophysiologic diagnosis has direct implications on treatment and patient outcomes. History and clinical examination is supplemented by selected investigations including the electrocardiogram, chest X-ray, echocardiography, coronary angiography, and even myocardial perfusion scintigraphy or cardiac magnetic resonance imaging. Intravascular imaging can provide ...
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    2. Coronary optical coherence tomography-derived virtual fractional flow reserve (FFR): anatomy and physiology all-in-one | European Heart Journal

      Coronary optical coherence tomography-derived virtual fractional flow reserve (FFR): anatomy and physiology all-in-one | European Heart Journal
      Most invasive coronary imaging modalities only provide anatomical information from which physiologic significance is inferred. Fractional flow reserve (FFR) and other physiologic indices of lesion severity are more reliable methods to identify physiologically significant lesions. Currently, accomplishing both anatomic and physiologic interrogation of an intermediate coronary stenosis requires the use of multiple devices within the coronary artery. Coronary angiography, optical coherence tomography (OCT), and FFR were performed in a left ...
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    3. Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography : A 4-Year Follow-Up Study

      Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography : A 4-Year Follow-Up Study
      Background Lipid-rich plaque (LRP) is thought to be a precursor to cardiac events. However, its clinical significance in coronary arteries has never been systematically investigated. Objectives This study investigated the prevalence and clinical significance of LRP in the nonculprit region of the target vessel in patients undergoing percutaneous coronary intervention (PCI). Methods The study included 1,474 patients from 20 sites across 6 countries undergoing PCI, who had optical coherence ...
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    4. Biomechanical stress in coronary atherosclerosis: emerging insights from computational modelling

      Biomechanical stress in coronary atherosclerosis: emerging insights from computational modelling
      Coronary plaque rupture is the most common cause of vessel thrombosis and acute coronary syndrome. The accurate early detection of plaques prone to rupture may allow prospective, preventative treatment; however, current diagnostic methods remain inadequate to detect these lesions. Established imaging features indicating vulnerability do not confer adequate specificity for symptomatic rupture. Similarly, even though experimental and computational studies have underscored the importance of endothelial shear stress in progressive atherosclerosis ...
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    5. Quantitative analysis of the side-branch orifice after bifurcation stenting using en-face processing of OCT images: a comparison between Xience V and Resolute Integrity stents

      Quantitative analysis of the side-branch orifice after bifurcation stenting using en-face processing of OCT images: a comparison between Xience V and Resolute Integrity stents
      Objective: Methods for intravascular assessment of the side-branch (SB) orifice after stenting are not readily available. The aim of this study was to assess the utility of an en-face projection processing for optical coherence tomography (OCT) images for SB evaluation. Methods: Measurements of the SB orifice obtained using en-face OCT images were validated using a phantom model. Linear regression modeling was applied to estimated area measurements made on the en-face ...
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    6. Advances in three-dimensional coronary imaging and computational fluid dynamics: is virtual fractional flow reserve more than just a pretty picture?

      Advances in three-dimensional coronary imaging and computational fluid dynamics: is virtual fractional flow reserve more than just a pretty picture?
      Percutaneous coronary intervention (PCI) has shown a high success rate in the treatment of coronary artery disease. The decision to perform PCI often relies on the cardiologists visual interpretation of coronary lesions during angiography. This has inherent limitations, particularly due to the low resolution and two-dimensional nature of angiography. State-of-the-art modalities such as three-dimensional quantitative coronary angiography, optical coherence tomography and invasive fractional flow reserve (FFR) may improve clinicians understanding ...
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    7. Optical coherence tomography to evaluate coronary stent implantation and complications

      Optical coherence tomography to evaluate coronary stent implantation and complications
      Coronary optical coherence tomography (OCT) is now an established imaging technique in many catheterization laboratories worldwide. With its near-histological view of the vessel wall and lumen interface, it offers unprecedented imaging quality to improve our understanding of the pathophysiology of atherosclerosis, plaque vulnerability, and vascular biology. Not only is OCT used to accurately detect atherosclerotic plaque and optimize stent position, but it can further characterize plaque composition, quantify stent apposition ...
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    8. Hazy filling defect on coronary angiography: insights from optical coherence tomography

      Hazy filling defect on coronary angiography: insights from optical coherence tomography
      A middle-aged patient with previous stent to the left circumflex artery (LCx) 12 months before suffering from angina, now presented with acute-onset severe retrosternal chest pain with an ECG showing ST-elevation in the precordial leads (see online supplementary figure S1). He underwent emergency coronary angiography, which showed normal flow in all arteries and a patent LCx stent. The left anterior descending artery (LAD) contained a hazy filling defect in the ...
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    9. Hazy filling defect on coronary angiography: insights from optical coherence tomography

      Hazy filling defect on coronary angiography: insights from optical coherence tomography
      A middle-aged patient with previous stent to the left circumflex artery (LCx) 12 months before suffering from angina, now presented with acute-onset severe retrosternal chest pain with an ECG showing ST-elevation in the precordial leads (see online supplementary figure S1). He underwent emergency coronary angiography, which showed normal flow in all arteries and a patent LCx stent. The left anterior descending artery (LAD) contained a hazy filling defect in the ...
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    10. Bivalirudin versus unfractionated heparin for residual thrombus burden: A frequency-domain optical coherence tomography study

      Bivalirudin versus unfractionated heparin for residual thrombus burden: A frequency-domain optical coherence tomography study
      ...n: A frequency-domain optical coherence tomography study 1. Rocco Vergallo MD^1, 2. Russell Joye BSBA^1, 3. Peter Barlis MBBS, PhD^2, 4. Haibo Jia MD, PhD^1, 5. Jinwei Tian MD, PhD^1, 6. Tsunenari Soeda MD, PhD^1, 7. Y...
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    11. Simultaneous single-vessel plaque rupture causing acute coronary syndrome detected by optical coherence tomography

      Simultaneous single-vessel plaque rupture causing acute coronary syndrome detected by optical coherence tomography
      A 67-year-old male presented with non-ST segment elevation myocardial infarction accompanied by inferior electrocardiogram (ECG) changes. Coronary angiography demonstrated a dominant right coronary artery (RCA) with two discrete regions of angiographic haziness, suggesting possible plaque ulceration and the presence of thrombus ( Panel A ). Prior studies have demonstrated non-culprit plaque rupture in acute myocardial infarction patients; however,
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    12. The invasive assessment of coronary atherosclerosis and stents using optical coherence tomography: a clinical update

      The invasive assessment of coronary atherosclerosis and stents using optical coherence tomography: a clinical update
      Ischaemic heart disease (IHD) remains one of the leading causes of death. Atherosclerosis has been intensely researched given the IHD prevalence and the financial impacts on healthcare systems. More recently, in vivo characterisation of coronary atherosclerotic plaque and tissue responses following stent implantation in a coronary artery has been made possible by a novel technology called optical coherence tomography (OCT). OCT is a light-based, invasive, intracoronary imaging modality long applied ...
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    13. Expert review document part 2: methodology, terminology and clinical applications of optical coherence tomography for the assessment of interventional procedures

      Expert review document part 2: methodology, terminology and clinical applications of optical coherence tomography for the assessment of interventional procedures
      Introduction This document is complementary to an Expert Review Document on Optical Coherence Tomography (OCT) for the study of coronary arteries and atherosclerosis.1 The goal of this companion manuscript is to provide a practical guide framework for the appropriate use and reporting of the novel frequency domain (FD) OCT imaging to guide interventional procedures, with a particular interest on the comparison with intravascular ultrasound (IVUS).1–4 Technique for ...
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    14. Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation

      Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation
      ..., MD, PhD, Writing Committee Co-Chair, Takashi Akasaka, MD, Writing Committee Co-Chair, Tom Adriaenssens, MD, Peter Barlis, MD, Hiram G. Bezerra, MD, Brett Bouma, PhD, Nico Bruining, PhD, Jin-man Cho, MD, PhD, Saqib Chow...
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    15. Intracoronary Optical Coherence Tomography for the Assessment of In-Stent Restenosis

      Intracoronary Optical Coherence Tomography for the Assessment of In-Stent Restenosis
      Optical coherence tomography (OCT) is a novel imaging modality in interventional cardiology. With its clear image quality, it has attracted considerable attention as a tool to accurately evaluate atherosclerosis and coronary stents in vivo. It has a 10-fold higher resolution compared to intravascular ultrasound and utilises near-infrared light that requires temporary blood clearance during image acquisition. We present a case of in-stent restenosis in a patient five years after percutaneous ...
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    16. Simple versus complex approaches to treating coronary bifurcation lesions: direct assessment of stent strut apposition by optical coherence tomography.

      Simple versus complex approaches to treating coronary bifurcation lesions: direct assessment of stent strut apposition by optical coherence tomography.
      Introduction and objectives. Stenting of coronary bifurcation lesions carries an increased risk of stent deformation and malapposition. Anatomical and pathological observations indicate that the high stent thrombosis rate in bifurcations is due to malapposition of stent struts. Methods. Strut apposition was assessed with optical coherence tomography (OCT) in bifurcation lesions treated either using the simple technique of stent implantation in the main vessel only or a complex technique (i.e ...
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    17. In-stent restenosis associated with stent malapposition: Seven year optical coherence tomography findings

      In-stent restenosis associated with stent malapposition: Seven year optical coherence tomography findings
      Abstract: Stent thrombosis and in-stent restenosis remain significant issues in post-coronary angioplasty care despite advances in anti-platelet therapy and stent technology. Angiographic predictors of stent failure have been proposed, but its precise mechanism has been difficult to elucidate on conventional coronary angiography and intravascular ultrasound due to the low resolution of either approach. Optical coherence tomography (OCT) as a high-resolution intracoronary imaging modality has enabled more detailed insight into the ...
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    18. 1-24 of 35 1 2 »
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  2. Organizations in the News

    1. (9 articles) Royal Brompton Hospital
    2. (7 articles) Harvard University
    3. (7 articles) Massachusetts General Hospital
    4. (6 articles) Erasmus University
    5. (6 articles) Imperial College London
    6. (3 articles) Kawasaki Medical School
    7. (2 articles) Massachusetts General Hospital OCT Registry
    8. (2 articles) Columbia University
    9. (2 articles) Massachusetts Institute of Technology
    10. (2 articles) Cardiovascular Research Foundation
    11. (2 articles) University of Pittsburgh
    12. (2 articles) Case Western Reserve University
  3. People in the News

    1. (9 articles) Carlo Di Mario
    2. (6 articles) Patrick W. Serruys
    3. (6 articles) Ik-Kyung Jang
    4. (5 articles) Evelyn Regar
    5. (4 articles) Nieves Gonzalo
    6. (4 articles) Giuseppe Ferrante
    7. (3 articles) Nicolas Foin
    8. (3 articles) Hang Lee
    9. (3 articles) Francesco Prati
    10. (3 articles) Shiro Uemura
    11. (2 articles) Guillermo J. Tearney
    12. (2 articles) Hiram G. Bezerra
  4. OCT Companies in the News

    1. (7 articles) St. Jude Medical
    2. (1 articles) Cordis
    3. (1 articles) Terumo Corporation