1. Articles mentioning both University of Illinois at Urbana-Champaign and Stephen A. Boppart

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    1. Optical coherence tomography imaging of excised canine apocrine gland anal sac adenocarcinoma tumors

      Optical coherence tomography imaging of excised canine apocrine gland anal sac adenocarcinoma tumors
      Optical coherence tomography (OCT) is an optical imaging modality that has been investigated for real‐time surgical margin evaluation in human breast cancer patients. Previous veterinary OCT studies have been limited to surgical margin imaging for soft tissue sarcoma (STS) tumors. To the authors knowledge, OCT has never been used to characterize or evaluate other types of neoplasia in dogs. The goal of this study was to characterize the OCT ...
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    2. Evaluating optical coherence tomography for surgical margin assessment of canine mammary tumors

      Evaluating optical coherence tomography for surgical margin assessment of canine mammary tumors
      Optical coherence tomography (OCT) uses near‐infrared light waves to generate real‐time, high‐resolution images on the microscopic scale similar to low power histopathology. Previous studies have demonstrated the use of OCT for real‐time surgical margin assessment for human breast cancer. The use of OCT for canine mammary tumors (CMT) could allow intra‐operative visualization of residual tumor at surgical margins. The purpose of this study was to ...
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    3. Otitis Media Middle Ear Effusion Identification and Characterization Using an Optical Coherence Tomography Otoscope

      Otitis Media Middle Ear Effusion Identification and Characterization Using an Optical Coherence Tomography Otoscope
      Objective To determine the feasibility of detecting and differentiating middle ear effusions (MEEs) using an optical coherence tomography (OCT) otoscope. Study Design Cross-sectional study. Setting US tertiary care childrens hospital. Subjects and Methods Seventy pediatric patients undergoing tympanostomy tube placement were preoperatively imaged using an OCT otoscope. A blinded reader quiz was conducted using 24 readers from 4 groups of tiered medical expertise. The primary outcome assessed was reader ability ...
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    4. University of Illinois at Urbana Champaign Receives NIH Grant for Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor Margins

      University of Illinois at Urbana Champaign Receives NIH Grant for Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor Margins
      ...r Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor Margins. The principal investigator is Stephen Boppart. Below is a summary of the proposed work. Breast cancer is a global healthcare burden, not on...
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    5. Assessing the Effect of Middle Ear Effusions on Wideband Acoustic Immittance Using Optical Coherence Tomography

      Assessing the Effect of Middle Ear Effusions on Wideband Acoustic Immittance Using Optical Coherence Tomography
      Objectives: Wideband acoustic immittance (WAI) noninvasively assesses middle ear function by measuring the sound conduction over a range of audible frequencies. Although several studies have shown the potential of WAI for detecting the presence of middle ear effusions (MEEs), determining the effects of MEE type and amount on WAI in vivo has been challenging due to the anatomical location of middle ear cavity. The purpose of this study is to ...
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    6. Method and apparatus for obtaining a three-dimensional map of tympanic membrane thickness

      Method and apparatus for obtaining a three-dimensional map of tympanic membrane thickness
      Methods and apparatus for combining a low coherence interferometry (LCI) technique for single-point thickness measurement with videootoscopy for recording the image of a tissue such as the tympanic membrane (TM). TM thickness distribution maps are obtained by mapping the LCI imaging sites onto an anatomically accurate wide-field image of the TM, generated by mosaicking a sequence of multiple small field-of-view video-otoscopy images.
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    7. Comparison between optical coherence tomographic and histopathologic appearances of artifacts caused by common surgical conditions and instrumentation

      Comparison between optical coherence tomographic and histopathologic appearances of artifacts caused by common surgical conditions and instrumentation
      Objective To document the appearance of artifacts created by commonly encountered surgical conditions and instrumentation on optical coherence tomography (OCT) and to compare these findings with histopathology. Study design Ex vivo study. Animals Five canine cadavers. Methods Skin, subcutaneous fat, skeletal muscle, and fascia samples were obtained from fresh canine cadavers. Blood pooling, hemostatic crushing, scalpel blade cut, monopolar electrosurgery, bipolar vessel sealing device, and ultrasonic energy surgical artifacts were ...
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    8. UIUC Receives NIH Grant for Integration of Raman Spectroscopy and OCT for In-vivo identification of Bacterial Otitis Media

      UIUC Receives NIH Grant for Integration of Raman Spectroscopy and OCT  for In-vivo identification of Bacterial Otitis Media
      ...rence Tomography (RS-OCT) for In-vivo identification of Bacterial Otitis Media. The principal investigator is Stephen Boppart. The program began in 2019 and ends in 2023. Below is a summary of the proposed work. Otitis ...
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    9. Method and apparatus for OCT-based viscometry

      Method and apparatus for OCT-based viscometry
      Methods and apparatus for ascertaining a relative viscosity characterizing a fluid sample. The fluid sample is illuminated through a scattering membrane adjacent to the fluid with broadband radiation. Scattering from particles within the fluid sample characterized by a distribution of characteristic dimensions spanning at least two orders of magnitude is detected, generating a detector signal as a function of depth relative to a specified surface of the scattering membrane at ...
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    10. Automated classification platform for the identification of otitis media using optical coherence tomography

      Automated classification platform for the identification of otitis media using optical coherence tomography
      The diagnosis and treatment of otitis media (OM), a common childhood infection, is a significant burden on the healthcare system. Diagnosis relies on observer experience via otoscopy, although for non-specialists or inexperienced users, accurate diagnosis can be difficult. In past studies, optical coherence tomography (OCT) has been used to quantitatively characterize disease states of OM, although with the involvement of experts to interpret and correlate image-based indicators of infection with ...
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    11. Local wavefront mapping in tissue using computational adaptive optics OCT

      Local wavefront mapping in tissue using computational adaptive optics OCT
      The identification and correction of wavefront aberrations is often necessary to achieve high-resolution optical images of biological tissues, as imperfections in the optical system and the tissue itself distort the imaging beam. Measuring the localized wavefront aberration provides information on where the beam is distorted and how severely. We have recently developed a method to estimate the single-pass wavefront aberrations from complex optical coherence tomography (OCT) data. Using this method ...
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    12. Interstitial magnetic thermotherapy dosimetry based on shear wave magnetomotive optical coherence elastography

      Interstitial magnetic thermotherapy dosimetry based on shear wave magnetomotive optical coherence elastography
      While magnetic thermoseeds are often utilized in interstitial magnetic thermotherapy (iMT) to enable localized tumor ablation, we propose to extend their use as the perturbative source in magnetomotive optical coherence elastography (MM-OCE) so that the heat-induced elasticity alterations can be theranostically probed. MM-OCE measurements were found to agree with indentation results. Tissue stiffening was visualized on iMT-treated porcine liver and canine soft tissue sarcoma specimens, where histology confirmed thermal damages ...
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    13. Economical and compact briefcase spectral-domain optical coherence tomography system for primary care and point-of-care applications

      Economical and compact briefcase spectral-domain optical coherence tomography system for primary care and point-of-care applications
      Development of low-cost and portable optical coherence tomography (OCT) systems is of global interest in the OCT research community. Such systems enable utility broadly throughout a clinical facility, or in remote areas that often lack clinical infrastructure. We report the development and validation of a low-cost, portable briefcase spectral-domain optical coherence tomography (SD-OCT) system for point-of-care diagnostics in primary care centers and/or in remote settings. The self-contained briefcase OCT ...
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    14. Intraoperative imaging of surgical margins of canine soft tissue sarcoma using optical coherence tomography

      Intraoperative imaging of surgical margins of canine soft tissue sarcoma using optical coherence tomography
      Optical coherence tomography (OCT) is a rapid non‐invasive imaging technique that has shown high sensitivity for intraoperative surgical margin assessment in human breast cancer clinical trials. This promising technology has not been evaluated in veterinary medicine. The objective of this study was to correlate normal and abnormal histological features with OCT images for surgical margins from excised canine soft tissue sarcoma (STS) and to establish image evaluation criteria for ...
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    15. Image Data Analyst, GlaxoSmithKline Center for Optical Molecular Imaging, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign

      Image Data Analyst, GlaxoSmithKline Center for Optical Molecular Imaging, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign
      ...st GlaxoSmithKline Center for Optical Molecular Imaging Beckman Institute for Advanced Science and Technology University of Illinois at Urbana-Champaign Solid and broad understanding of image analysis software as well as...
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    16. Imaging Research Scientist, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign

      Imaging Research Scientist, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign
      ...ore about the Universitys commitment to diversity, please visit http://www.inclusiveillinois.illinois.edu The Biophotonics Imaging Laboratory and the Center for Optical Molecular Imaging at the Beckman Institute for Adva...
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    17. PhotoniCare Receives $2.1 Million National Institute of Health Phase IIb Small Business Innovation Research Award

      PhotoniCare Receives $2.1 Million National Institute of Health Phase IIb Small Business Innovation Research Award
      ...ost common diseases in the world. Founded out of Dr. Stephen Boppart’s Biophotonics Imaging Laboratory at the University of Illinois at Urbana-Champaign (UIUC), PhotoniCare continues its relationship with UIUC as an Ente...
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    18. Magnetomotive Displacement of the Tympanic Membrane using Magnetic Nanoparticles: Toward Enhancement of Sound Perception

      Magnetomotive Displacement of the Tympanic Membrane using Magnetic Nanoparticles: Toward Enhancement of Sound Perception
      Objective: A novel hearing-aid scheme using magnetomotive nanoparticles (MNPs) as transducers in the tympanic membrane (TM) is proposed, aiming to noninvasively and directly induce a modulated vibration on the TM. Methods: In this feasibility study, iron-oxide (Fesub3/subOsub4/sub) nanoparticles were applied on ex vivo rat TM tissues and allowed to diffuse over ~2 hr. Subsequently, magnetic force was exerted on the MNP-laden TM via a programmable electromagnetic solenoid to ...
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    19. Wavefront measurement using computational adaptive optics

      Wavefront measurement using computational adaptive optics
      In many optical imaging applications, it is necessary to correct for aberrations to obtain high quality images. Optical coherence tomography (OCT) provides access to the amplitude and phase of the backscattered optical field for three-dimensional (3D) imaging samples. Computational adaptive optics (CAO) modifies the phase of the OCT data in the spatial frequency domain to correct optical aberrations without using a deformable mirror, as is commonly done in hardware-based adaptive ...
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    20. Label-free optical imaging technologies for rapid translation and use during intraoperative surgical and tumor margin assessment

      Label-free optical imaging technologies for rapid translation and use during intraoperative surgical and tumor margin assessment
      The biannual International Conference on Biophotonics was recently held on April 30 to May 1, 2017, in Fremantle, Western Australia. This continuing conference series brought together key opinion leaders in biophotonics to present their latest results and, importantly, to participate in discussions on the future of the field and what opportunities exist when we collectively work together for using biophotonics for biological discovery and medical applications. One session in this ...
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  2. Organizations in the News

    1. (23 articles) National Institutes of Health
    2. (7 articles) Kyungpook National University
    3. (6 articles) Massachusetts Institute of Technology
    4. (6 articles) Duke University
    5. (5 articles) Massachusetts General Hospital
    6. (5 articles) University of Western Australia
    7. (4 articles) Cornell University
    8. (4 articles) Purdue University
    9. (4 articles) Harvard University
    10. (3 articles) UC Irvine
    11. (3 articles) University of Pittsburgh
    12. (2 articles) Johns Hopkins University
  3. People in the News

    1. (37 articles) Eric J. Chaney
    2. (37 articles) P. Scott Carney
    3. (36 articles) Steven G. Adie
    4. (22 articles) Daniel L. Marks
    5. (20 articles) Ryan L. Shelton
    6. (20 articles) Nathan D. Shemonski
    7. (18 articles) Adeel Ahmad
    8. (18 articles) Guillermo L. Monroy
    9. (17 articles) Marina Marjanovic
    10. (15 articles) Fredrick A. South
    11. (12 articles) Paritosh Pande
    12. (12 articles) Tyler S. Ralston
  4. OCT Companies in the News

    1. (4 articles) Diagnostic Photonics
    2. (4 articles) Blue Highway, LLC
    3. (4 articles) PhotoniCare
    4. (3 articles) Abbot
    5. (2 articles) Optovue
    6. (1 articles) Lantis Laser
    7. (1 articles) Optopol Technology
    8. (1 articles) Cambridge Technology
    9. (1 articles) Tomophase Corporation
    10. (1 articles) Heliotis AG
    11. (1 articles) Nexus Imaging Systems
    12. (1 articles) OCT Medical Imaging Inc