1. Articles mentioning both University of Bern and Sebastian Wolf

    1-22 of 22
    1. Spectral-Domain Optical Coherence Tomography Associations of Neovascular Conversion in Age-Related Macular Degeneration

      Spectral-Domain Optical Coherence Tomography Associations of Neovascular Conversion in Age-Related Macular Degeneration
      Purpose: To identify spectral-domain optical coherence tomography (SD-OCT) features associated with exudative conversion in fellow eyes of patients treated for neovascular age-related macular degeneration (nAMD) in their first eye. Methods: Retrospective observational study. Spectral-domain optical coherence tomography images of converting fellow eyes (study eyes) from 83 patients with nAMD were compared to fellow eyes of age- and sex-matched patients with nAMD who did not convert (control eyes). Parameters related to ...
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    2. Relationship Between Presumptive Inner Nuclear Layer Thickness and Geographic Atrophy Progression in Age-Related Macular Degeneration

      Relationship Between Presumptive Inner Nuclear Layer Thickness and Geographic Atrophy Progression in Age-Related Macular Degeneration
      Purpose : To analyze inner retinal changes in patients with geographic atrophy (GA) secondary to age-related macular degeneration and identify morphological cues for progression. Methods : A total of 100 eyes with GA were assessed in this longitudinal, observational case series. Patients with GA and absent confounding pathology were compared with age-matched controls. The retinal layers on spectral-domain optical coherence tomography, acquired in tracking mode, were segmented manually on central scans through ...
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    3. Automatic assessment of time-resolved OCT images for selective retina therapy

      Automatic assessment of time-resolved OCT images for selective retina therapy
      Purpose In recent years, selective retina laser treatment (SRT), a sub-threshold therapy method, avoids widespread damage to all retinal layers by targeting only a few. While these methods facilitate faster healing, their lack of visual feedback during treatment represents a considerable shortcoming as induced lesions remain invisible with conventional imaging and make clinical use challenging. To overcome this, we present a new strategy to provide location-specific and contact-free automatic feedback ...
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    4. Time-Resolved Ultra–High Resolution Optical Coherence Tomography for Real-Time Monitoring of Selective Retina Therapy

      Time-Resolved Ultra–High Resolution Optical Coherence Tomography for Real-Time Monitoring of Selective Retina Therapy
      Purpose : Selective retina therapy (SRT) is a novel treatment for retinal pathologies, solely targeting the RPE. During SRT, the detection of an immediate tissue reaction is challenging, as tissue effects remain limited to intracellular RPE photodisruption. Time-resolved ultra-high axial resolution optical coherence tomography (OCT) is thus evaluated for the monitoring of dynamic optical changes at and around the RPE during SRT. Methods : An experimental OCT system with an ultra-high axial ...
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    5. The Presence of Intra- or Subretinal Fluid during the Loading Phase in the Treatment of Exudative Age-Related Macular Degeneration with Intravitreal Ranibizumab Assessed by Optical Coherence Tomography

      The Presence of Intra- or Subretinal Fluid during the Loading Phase in the Treatment of Exudative Age-Related Macular Degeneration with Intravitreal Ranibizumab Assessed by Optical Coherence Tomography
      Purpose: To assess intra- and subretinal fluid during the loading phase with intravitreal ranibizumab in exudative age-related macular degeneration and to quantify the accuracy of crosshair scan spectral-domain optical coherence tomography with regard to retinal fluid. Methods: This is a retrospective study of 31 treatment-naive patients who received 3 monthly intravitreal ranibizumab injections. Visual acuity and the presence of retinal fluid were assessed at each visit using volume and crosshair ...
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    6. Assessment of ultra-high resolution optical coherence tomography for monitoring tissue effects caused by laser photocoagulation of ex-vivo porcine retina

      Assessment of ultra-high resolution optical coherence tomography for monitoring tissue effects caused by laser photocoagulation of ex-vivo porcine retina
      ...tissue effects caused by laser photocoagulation of ex-vivo porcine retina Patrick Steiner ; Volker Enzmann ; Sebastian Wolf ; Anke Bossen ; Christoph Meier ; Raphael Sznitman; Assessment of ultra-high resolution optical...
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    7. Spectral-domain Optical Coherence Tomography Findings after Severe Exogenous Endophthalmitis

      Spectral-domain Optical Coherence Tomography Findings after Severe Exogenous Endophthalmitis
      Purpose : To report outcomes and assess structural changes in the retina in patients with severe endophthalmitis . Methods : Retrospective, nonrandomized, interventional case series at a tertiary referral centre. Spectral domain optical coherence tomography (OCT) images of both eyes were acquired at least 5 months after pars plana vitrectomy. OCT images were analyzed using retinal layer segmentation. Results : Nine patients (4680 years of age) were included in this study. Average ETDRS visual ...
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    8. Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria

      Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria
      Background: Retinal optical coherence tomography (OCT) permits quantification of retinal layer atrophy relevant to assessment of neurodegeneration in multiple sclerosis (MS). Measurement artefacts may limit the use of OCT to MS research. Objective: An expert task force convened with the aim to provide guidance on the use of validated quality control (QC) criteria for the use of OCT in MS research and clinical trials. Methods: A prospective multi-centre ( n = 13 ...
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    9. Behaviour of SD-OCT detected hyperreflective foci in the retina of Anti-VEGF treated patients with Diabetic Macular Edema

      Behaviour of SD-OCT detected hyperreflective foci in the retina of Anti-VEGF treated patients with Diabetic Macular Edema
      Purpose:Hyperreflective foci (HF) are observable within the neurosensory retina in diabetic macular edema (DME) using spectral domain optical coherence tomography (SD-OCT). The HF behaviour was evaluated during Anti-VEGF therapy in DME. Methods: Fifty-one patients (mean age: 67 years) underwent SD-OCT (Heidelberg engineering, Germany) before and one month after one Anti-VEGF injection (Ranibizumab: n=30; Bevacizumab: n=21). The amount of HFs were semi-quantitatively counted, assigned to 3 groups (A ...
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    10. Optical coherence tomography (Article by Dr. Sebastian Wolf)

      Optical coherence tomography (Article by Dr. Sebastian Wolf)
      The introduction of optical coherence tomography (OCT) in 1991 by Huang and associates,1 has become a tremendous turning point in the development of the ophthalmic imaging field. Clinical application of OCT in ophthalmology has undergone rapid evolution especially with the introduction spectral domain OCT (SD-OCT).
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    11. Small Dense Particles in the Retina Observable by Spectral-Domain Optical Coherence Tomography in Age-Related Macular Degeneration

      Small Dense Particles in the Retina Observable by Spectral-Domain Optical Coherence Tomography in Age-Related Macular Degeneration
      Purpose. To observe detailed changes in neurosensory retinal structure after anti-VEGF upload in age-related macular degeneration (AMD), by using spectral domain optical coherence tomography (SD-OCT). Methods. The retinal structure was observed by using SD-OCT in 61 patients, before and 1 month after the third ranibizumab injection (upload phase). The main focus of attention was a subjective determination of the amount and behavior of the numerous small, dense particles (SDPs) frequently ...
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    12. Small dense particles within the neurosensory retinal layers observable by Spectral Domain Optical Coherence Tomography in Age-related macular Degeneration

      Small dense particles within the neurosensory retinal layers observable by Spectral Domain Optical Coherence Tomography in Age-related macular Degeneration
      ...usch^3 ^^1Department of Ophthalmology, University of Bern, Bern, Switzerland^ ^2Department of Ophthalmology, University of Bern, Bern, Switzerland^ ^3Department of Ophthalmology, University of Bern, Bern, Switzerland ^ ...
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    13. Spectral-Domain Optical Coherence Tomography Use in Macular Diseases: A Review

      Spectral-Domain Optical Coherence Tomography Use in Macular Diseases: A Review
      The introduction of spectral-domain optical coherence tomography (SD-OCT) has improved the clinical value for assessment of the eyes with macular disease. This article reviews the advances of SD-OCT for the diagnostic of various macular diseases. These include vitreomacular traction syndrome, cystoid macular edema/diabetic macular edema, epiretinal membranes, full-thickness macular holes, lamellar holes, pseudoholes, microholes, and schisis from myopia. Besides offering new insights into the pathogenesis of macular abnormalities, SD-OCT ...
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    14. Morphologic Changes in Patients with Geographic Atrophy Assessed with a Novel Spectral OCT-SLO Combination

      purpose. To investigate the appearance of geographic atrophy in high-resolution optical coherence tomography (OCT) images, the fundus autofluorescence (FAF) pattern, and infrared images simultaneously recorded with a novel combined OCT-scanning laser ophthalmology (SLO) system. methods. Patients aged over 50 years with geographic atrophy secondary to dry age-related macular degeneration (ARMD) were assessed in a prospective cross-sectional study by means of simultaneous spectral OCT-SLO (Spectralis HRA+OCT; Heidelberg Engineering, Heidelberg, Germany ...
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    15. Impact of optic media opacities and image compression on quantitative analysis of optical coherence tomography.

      PURPOSE: To analyze the impact of opacities in the optical pathway and image compression of 32-bit raw data to 8-bit jpg images on quantified optical coherence tomography (OCT) image analysis. METHODS: In 18 eyes of nine healthy subjects, OCT images were acquired from the central macula. To simulate opacities in the optical system, neutral-density (ND) filters with linear absorption spectra were placed between the OCT device and examined eyes. Light ...
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    16. 1-22 of 22
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  2. Organizations in the News

    1. (5 articles) Bern University Hospital
    2. (1 articles) University of Sydney
    3. (1 articles) Johns Hopkins University
    4. (1 articles) University of Lübeck
    5. (1 articles) University of Hannover
    6. (1 articles) University Hospital Zurich
    7. (1 articles) VU University Amsterdam
    8. (1 articles) UCSF
    9. (1 articles) University of Copenhagen
    10. (1 articles) Heinrich-Heine University Düsseldorf
    11. (1 articles) UT Southwestern Medical Center
    12. (1 articles) University of Calgary
  3. People in the News

    1. (6 articles) Carsten Framme
    2. (6 articles) Martin S. Zinkernagel
    3. (3 articles) Patrick Steiner
    4. (3 articles) University of Leipzig
    5. (2 articles) Christoph Meier
    6. (1 articles) Alexander Klistorner
    7. (1 articles) Peter A. Calabresi
    8. (1 articles) Laura J. Balcer
    9. (1 articles) Axel Petzold
    10. (1 articles) Friedemann Paul
    11. (1 articles) Elliot M. Frohman
    12. (1 articles) Fiona E. Costello
  4. OCT Companies in the News

    1. (2 articles) Optos
    2. (2 articles) Heidelberg Engineering
    3. (1 articles) Optovue
    4. (1 articles) Carl Zeiss Meditec
    5. (1 articles) Optopol Technology