1. Articles mentioning both Tsung-Han Tsai and James G. Fujimoto

    1-24 of 34 1 2 »
    1. Endoscopic forward-viewing optical coherence tomography and angiography with MHz swept source

      Endoscopic forward-viewing optical coherence tomography and angiography with MHz swept source
      Endoscopic optical coherence tomography (OCT) instruments are mostly side viewing and rely on at least one proximal scan, thus limiting accuracy of volumetric imaging and en face visualization. Previous forward-viewing OCT devices had limited axial scan speeds. We report a forward-viewing fiber scanning 3D-OCT probe with 900 m field of view and 5 m transverse resolution, imaging at 1 MHz axial scan rate in the human gastrointestinal tract. The probe ...
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    2. Assessment of the radiofrequency ablation dynamics of esophageal tissue with optical coherence tomography

      Assessment of the radiofrequency ablation dynamics of esophageal tissue with optical coherence tomography
      Radiofrequency ablation (RFA) is widely used for the eradication of dysplasia and the treatment of early stage esophageal carcinoma in patients with Barretts esophagus (BE). However, there are several factors, such as variation of BE epithelium (EP) thickness among individual patients and varying RFA catheter-tissue contact, which may compromise RFA efficacy. We used a high-speed optical coherence tomography (OCT) system to identify and monitor changes in the esophageal tissue architecture ...
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    3. Feature Of The Week 03/08/2015: Endoscopic Optical Coherence Angiography Enables Three Dimensional Visualization of Subsurface Microvasculature

      Feature Of The Week 03/08/2015: Endoscopic Optical Coherence Angiography Enables Three Dimensional Visualization of Subsurface Microvasculature
      ...phy for Gastroenterology , Biomedical Optics Express 5 (12), 4387-4404 (2014). Courtesy of Tsung-Han Tsal and James Fujimoto and from Massachusetts Institute of Technology . To share this article click Here . Endoscopic ...
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    4. Ultrahigh speed endoscopic optical coherence tomography for gastroenterology

      Ultrahigh speed endoscopic optical coherence tomography for gastroenterology
      We describe an ultrahigh speed endoscopic swept source optical coherence tomography (OCT) system for clinical gastroenterology using a vertical-cavity surface-emitting laser (VCSEL) and micromotor imaging catheter. The system had a 600 kHz axial scan rate and 8 m axial resolution in tissue. Imaging was performed with a 3.2 mm diameter imaging catheter at 400 frames per second with a 12 m spot size. Three-dimensional OCT (3D-OCT) imaging was performed ...
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    5. Ultrahigh speed endoscopic swept source optical coherence tomography using a VCSEL light source and micromotor catheter

      Ultrahigh speed endoscopic swept source optical coherence tomography using a VCSEL light source and micromotor catheter
      ...man ; Martin F. Kraus ; Joachim Hornegger ; Marisa Figueiredo ; Qin Huang ; Hiroshi Mashimo ; Alex E. Cable ; James G. Fujimoto; Ultrahigh speed endoscopic swept source optical coherence tomography using a VCSEL light so...
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    6. Swept source optical coherence microscopy using a 1310 nm VCSEL light source

      Swept source optical coherence microscopy using a 1310 nm VCSEL light source
      We demonstrate high speed, swept source optical coherence microscopy (OCM) using a MEMS tunable vertical cavity surface-emitting laser (VCSEL) light source. The light source had a sweep rate of 280 kHz, providing a bidirectional axial scan rate of 560 kHz. The sweep bandwidth was 117 nm centered at 1310 nm, corresponding to an axial resolution of 13.1 m in air, corresponding to 8.1 m (9.6 m spectrally ...
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    7. Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology

      Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology
      ...s Jiang, Peter J. S. Heim, Martin F. Kraus, Chao Zhou, Joachim Hornegger, Hiroshi Mashimo, Alex E. Cable, and James G. Fujimoto »View Author Affiliations Tsung-Han Tsai,^1 Benjamin Potsaid,^1,^2 Yuankai K. Tao,^1 Vijays...
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    8. Ultrahigh speed endoscopic optical coherence tomography using micro-motor imaging catheter and VCSEL technology

      Ultrahigh speed endoscopic optical coherence tomography using micro-motor imaging catheter and VCSEL technology
      ...sekhar Jayaraman ; Martin F. Kraus ; Peter J. S. Heim ; Joachim Hornegger ; Hiroshi Mashimo ; Alex E. Cable ; James G. Fujimoto; Ultrahigh speed endoscopic optical coherence tomography using micro-motor imaging catheter ...
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    9. Structural markers observed with endoscopic 3-dimensional optical coherence tomography correlating with Barrett's esophagus radiofrequency ablation treatment response (with videos)

      Structural markers observed with endoscopic 3-dimensional optical coherence tomography correlating with Barrett's esophagus radiofrequency ablation treatment response (with videos)
      ...Affiliations + Veterans Affairs Boston Healthcare System, Boston, MA + Harvard Medical School, Boston, MA , * James G. Fujimoto, PhD Affiliations + Department of Electrical Engineering & Computer Science, Research Labora...
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    10. Comparison of Tissue Architectural Changes between Radiofrequency Ablation and Cryospray Ablation in Barrett’s Esophagus Using Endoscopic Three-Dimensional Optical Coherence Tomography

      Comparison of Tissue Architectural Changes between Radiofrequency Ablation and Cryospray Ablation in Barrett’s Esophagus Using Endoscopic Three-Dimensional Optical Coherence Tomography
      Two main nonsurgical endoscopic approaches for ablating dysplastic and early cancer lesions in the esophagus have gained popularity, namely, radiofrequency ablation (RFA) and cryospray ablation (CSA). We report a uniquely suited endoscopic and near-microscopic imaging modality, three-dimensional (3D) optical coherence tomography (OCT), to assess and compare the esophagus immediately after RFA and CSA. The maximum depths of architectural changes were measured and compared between the two treatment groups. RFA was ...
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    11. Characterization of buried glands before and after radiofrequency ablation by using 3-dimensional optical coherence tomography (with videos)

      Characterization of buried glands before and after radiofrequency ablation by using 3-dimensional optical coherence tomography (with videos)
      Background: Radiofrequency ablation (RFA) is an endoscopic technique used to eradicate Barrett's esophagus (BE). However, such ablation can commonly lead to neosquamous epithelium overlying residual BE glands not visible by conventional endoscopy and may evade detection on random biopsy samples.Objective: To demonstrate the capability of endoscopic 3-dimensional optical coherence tomography (3D-OCT) for the identification and characterization of buried glands before and after RFA therapy.Design: Cross-sectional study.Setting ...
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    12. Changes in the Expression of the Alzheimer's Disease-Associated Presenilin Gene in Drosophila Heart Leads to Cardiac Dysfunction

      Changes in the Expression of the Alzheimer's Disease-Associated Presenilin Gene in Drosophila Heart Leads to Cardiac Dysfunction
      ..., T.-H. Tsai, H.-C. Lee, D. M. Romano, M. L.McKee, D. A. Schoenfeld, M. J. Serra, K. Raygor, H. F. Cantiello, J. G. Fujimoto, R. E. Tanzi Abstract Mutations in the presenilin genes cause the majority of early-onset fami...
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    13. Piezoelectric transducer based miniature catheter for ultrahigh speed endoscopic optical coherence tomography

      Piezoelectric transducer based miniature catheter for ultrahigh speed endoscopic optical coherence tomography
      ...strated. Tsung-Han Tsai, Benjamin M. Potsaid, Martin Kraus, Jonathan J. Liu, Chao Zhou, Joachim Hornegger and James G. Fujimoto, "Piezoelectric transducer based miniature catheter for ultrahigh speed endoscopic optical c...
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    14. Integrated Optical Coherence Tomography and Microscopy for Ex Vivo Multiscale Evaluation of Human Breast Tissues

      Integrated Optical Coherence Tomography and Microscopy for Ex Vivo Multiscale Evaluation of Human Breast Tissues
      3D tissue imaging methods are expected to improve surgical management of cancer. In this study, we examined the feasibility of two 3D imaging technologies, optical coherence tomography (OCT) and optical coherence microscopy (OCM), to view human breast specimens based on intrinsic optical contrast. Specifically, we imaged 44 ex vivo breast specimens including 34 benign and 10 malignant lesions with an integrated OCT and OCM system developed in our laboratory. The ...
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    15. 1-24 of 34 1 2 »
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  2. Organizations in the News

    1. (34 articles) Massachusetts Institute of Technology
    2. (16 articles) Harvard University
    3. (5 articles) Beth Israel Deaconess Medical Center
    4. (5 articles) University of Erlangen
    5. (2 articles) Johns Hopkins University
    6. (2 articles) Massachusetts General Hospital
    7. (1 articles) Tsinghua University
    8. (1 articles) University of Wisconsin
  3. People in the News

    1. (21 articles) Chao Zhou
    2. (19 articles) Hiroshi Mashimo
    3. (19 articles) Hsiang-Chieh Lee
    4. (14 articles) Benjamin M. Potsaid
    5. (13 articles) Yuankai K. Tao
    6. (12 articles) Desmond C. Adler
    7. (12 articles) Osman O. Ahsen
    8. (10 articles) Joseph M. Schmitt
    9. (10 articles) Vijay Jayaraman
    10. (9 articles) Alex E. Cable
    11. (6 articles) James L. Connolly
    12. (6 articles) Martin F. Kraus
  4. OCT Companies in the News

    1. (12 articles) Thorlabs
    2. (11 articles) Abbot
    3. (10 articles) Praevium Research