1. Articles mentioning both Tsung-Han Tsai and Harvard University

    1-17 of 17
    1. Optical coherence tomography in gastroenterology: a review and future outlook

      Optical coherence tomography in gastroenterology: a review and future outlook
      Optical coherence tomography (OCT) is an imaging technique optically analogous to ultrasound that can generate depth-resolved images with micrometer-scale resolution. Advances in fiber optics and miniaturized actuation technologies allow OCT imaging of the human body and further expand OCT utilization in applications including but not limited to cardiology and gastroenterology. This review article provides an overview of current OCT development and its clinical utility in the gastrointestinal tract, including disease ...
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    2. Endoscopic forward-viewing optical coherence tomography and angiography with MHz swept source

      Endoscopic forward-viewing optical coherence tomography and angiography with MHz swept source
      Endoscopic optical coherence tomography (OCT) instruments are mostly side viewing and rely on at least one proximal scan, thus limiting accuracy of volumetric imaging and en face visualization. Previous forward-viewing OCT devices had limited axial scan speeds. We report a forward-viewing fiber scanning 3D-OCT probe with 900 m field of view and 5 m transverse resolution, imaging at 1 MHz axial scan rate in the human gastrointestinal tract. The probe ...
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    3. Assessment of the radiofrequency ablation dynamics of esophageal tissue with optical coherence tomography

      Assessment of the radiofrequency ablation dynamics of esophageal tissue with optical coherence tomography
      Radiofrequency ablation (RFA) is widely used for the eradication of dysplasia and the treatment of early stage esophageal carcinoma in patients with Barretts esophagus (BE). However, there are several factors, such as variation of BE epithelium (EP) thickness among individual patients and varying RFA catheter-tissue contact, which may compromise RFA efficacy. We used a high-speed optical coherence tomography (OCT) system to identify and monitor changes in the esophageal tissue architecture ...
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    4. Feature Of The Week 03/08/2015: Endoscopic Optical Coherence Angiography Enables Three Dimensional Visualization of Subsurface Microvasculature

      Feature Of The Week 03/08/2015: Endoscopic Optical Coherence Angiography Enables Three Dimensional Visualization of Subsurface Microvasculature
      Endoscopic imaging technologies such as confocal laser endomicroscopy (CLE) and narrowband imaging (NBI) have been used to investigate vascular changes as hallmarks of early cancer in the GI tract. However, the limited frame rate and field of view make CLE imaging sensitive to motion artifacts, whereas NBI has limited resolution and visualizes only the surface vascular pattern. Endoscopic optical coherence tomography (OCT) enables high speed volumetric imaging of subsurface features ...
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    5. Ultrahigh speed endoscopic optical coherence tomography for gastroenterology

      Ultrahigh speed endoscopic optical coherence tomography for gastroenterology
      We describe an ultrahigh speed endoscopic swept source optical coherence tomography (OCT) system for clinical gastroenterology using a vertical-cavity surface-emitting laser (VCSEL) and micromotor imaging catheter. The system had a 600 kHz axial scan rate and 8 m axial resolution in tissue. Imaging was performed with a 3.2 mm diameter imaging catheter at 400 frames per second with a 12 m spot size. Three-dimensional OCT (3D-OCT) imaging was performed ...
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    6. Structural markers observed with endoscopic 3-dimensional optical coherence tomography correlating with Barrett's esophagus radiofrequency ablation treatment response (with videos)

      Structural markers observed with endoscopic 3-dimensional optical coherence tomography correlating with Barrett's esophagus radiofrequency ablation treatment response (with videos)
      ...hool, Boston, MA , * Tejas Kirtane, MD Affiliations + Veterans Affairs Boston Healthcare System, Boston, MA + Harvard Medical School, Boston, MA , * Desmond C. Adler, PhD Affiliations + LightLab Imaging Inc, St. Jude Med...
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    7. Comparison of Tissue Architectural Changes between Radiofrequency Ablation and Cryospray Ablation in Barrett’s Esophagus Using Endoscopic Three-Dimensional Optical Coherence Tomography

      Comparison of Tissue Architectural Changes between Radiofrequency Ablation and Cryospray Ablation in Barrett’s Esophagus Using Endoscopic Three-Dimensional Optical Coherence Tomography
      Two main nonsurgical endoscopic approaches for ablating dysplastic and early cancer lesions in the esophagus have gained popularity, namely, radiofrequency ablation (RFA) and cryospray ablation (CSA). We report a uniquely suited endoscopic and near-microscopic imaging modality, three-dimensional (3D) optical coherence tomography (OCT), to assess and compare the esophagus immediately after RFA and CSA. The maximum depths of architectural changes were measured and compared between the two treatment groups. RFA was ...
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    8. Characterization of buried glands before and after radiofrequency ablation by using 3-dimensional optical coherence tomography (with videos)

      Characterization of buried glands before and after radiofrequency ablation by using 3-dimensional optical coherence tomography (with videos)
      Background: Radiofrequency ablation (RFA) is an endoscopic technique used to eradicate Barrett's esophagus (BE). However, such ablation can commonly lead to neosquamous epithelium overlying residual BE glands not visible by conventional endoscopy and may evade detection on random biopsy samples.Objective: To demonstrate the capability of endoscopic 3-dimensional optical coherence tomography (3D-OCT) for the identification and characterization of buried glands before and after RFA therapy.Design: Cross-sectional study.Setting ...
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    9. Ex vivo imaging of human thyroid pathology using integrated optical coherence tomography and optical coherence microscopy

      Ex vivo imaging of human thyroid pathology using integrated optical coherence tomography and optical coherence microscopy
      ...cs, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139 Yihong Wang Beth Israel Deaconess Medical Center, Harvard Medical School, Department of Pathology, 330 Brookline Avenue, Boston, Massachusetts 02215 and Montefi...
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    10. Three-dimensional optical coherence tomography of Barrett’s esophagus and buried glands beneath neosquamous epithelium following radiofrequency ablation

      ...tute of Technology, Cambridge, Massachusetts, USA 2 VA Boston Healthcare System, Boston, Massachusetts, USA 3 Harvard Medical School, Boston, Massachusetts, USA 4 LightLab Imaging Inc., Westford, Massachusetts, USA ...
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    11. 1-17 of 17
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  2. Organizations in the News

    1. (16 articles) Massachusetts Institute of Technology
    2. (2 articles) Beth Israel Deaconess Medical Center
    3. (1 articles) Academic Medical Center at the University of Amsterdam
    4. (1 articles) Columbia University
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  3. People in the News

    1. (16 articles) James G. Fujimoto
    2. (13 articles) Hiroshi Mashimo
    3. (12 articles) Hsiang-Chieh Lee
    4. (10 articles) Chao Zhou
    5. (9 articles) Desmond C. Adler
    6. (8 articles) Joseph M. Schmitt
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  4. OCT Companies in the News

    1. (9 articles) Abbot
    2. (4 articles) Thorlabs
    3. (3 articles) Praevium Research
    4. (1 articles) NinePoint Medical