1. Articles mentioning both Stephen A. Boppart and P. Scott Carney

    1-24 of 39 1 2 »
    1. Wavefront measurement using computational adaptive optics

      Wavefront measurement using computational adaptive optics
      In many optical imaging applications, it is necessary to correct for aberrations to obtain high quality images. Optical coherence tomography (OCT) provides access to the amplitude and phase of the backscattered optical field for three-dimensional (3D) imaging samples. Computational adaptive optics (CAO) modifies the phase of the OCT data in the spatial frequency domain to correct optical aberrations without using a deformable mirror, as is commonly done in hardware-based adaptive ...
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    2. Computational optical coherence tomography [Invited]

      Computational optical coherence tomography [Invited]
      Optical coherence tomography (OCT) has become an important imaging modality with numerous biomedical applications. Challenges in high-speed, high-resolution, volumetric OCT imaging include managing dispersion, the trade-off between transverse resolution and depth-of-field, and correcting optical aberrations that are present in both the system and sample. Physics-based computational imaging techniques have proven to provide solutions to these limitations. This review aims to outline these computational imaging techniques within a general mathematical framework ...
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    3. Inverse scattering for frequency-scanned full-field optical coherence tomography

      Inverse scattering for frequency-scanned full-field optical coherence tomography
      Full-field optical coherence tomography (OCT) is able to image an entire en face plane of scatterers simultaneously, but typically the focus is scanned through the volume to acquire three-dimensional structure. By solving the inverse scattering problem for full-field OCT, we show it is possible to computationally reconstruct a three-dimensional volume while the focus is fixed at one plane inside the sample. While a low-numerical-aperture (NA) OCT system can tolerate defocus ...
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    4. Filtering for unwrapping noisy Doppler optical coherence tomography images for extended microscopic fluid velocity measurement range

      Filtering for unwrapping noisy Doppler optical coherence tomography images for extended microscopic fluid velocity measurement range
      ...hor: Carney@illinois.edu Yang Xu, Donald Darga, Jason Smid, Adam M. Zysk, Daniel Teh, Stephen A. Boppart, and P. Scott Carney, "Filtering for unwrapping noisy Doppler optical coherence tomography images for extended micr...
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    5. Computational adaptive optics of the human retina

      Computational adaptive optics of the human retina
      It is well known that patient-specific ocular aberrations limit imaging resolution in the human retina. Previously, hardware adaptive optics (HAO) has been employed to measure and correct these aberrations to acquire high-resolution images of various retinal structures. While the resulting aberration-corrected images are of great clinical importance, clinical use of HAO has not been widespread due to the cost and complexity of these systems. We present a technique termed computational ...
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    6. Automated interferometric synthetic aperture microscopy and computational adaptive optics for improved optical coherence tomography

      Automated interferometric synthetic aperture microscopy and computational adaptive optics for improved optical coherence tomography
      ...Illinois 61801, USA *Corresponding author: Carney@illinois.edu Yang Xu, Yuan-Zhi Liu, Stephen A. Boppart, and P. Scott Carney, "Automated interferometric synthetic aperture microscopy and computational adaptive optics fo...
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    7. Polarization-sensitive interferometric synthetic aperture microscopy

      Polarization-sensitive interferometric synthetic aperture microscopy
      Three-dimensional optical microscopy suffers from the well-known compromise between transverse resolution and depth-of-field. This is true for both structural imaging methods and their functional extensions. Interferometric synthetic aperture microscopy (ISAM) is a solution to the 3D coherent microscopy inverse problem that provides depth-independent transverse resolution. We demonstrate the extension of ISAM to polarization sensitive imaging, termed polarization-sensitive interferometric synthetic aperture microscopy (PS-ISAM). This technique is the first functionalization of the ...
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    8. Intraoperative Assessment of Final Margins with a Handheld Optical Imaging Probe During Breast-Conserving Surgery May Reduce the Reoperation Rate: Results of a Multicenter Stud

      Intraoperative Assessment of Final Margins with a Handheld Optical Imaging Probe During Breast-Conserving Surgery May Reduce the Reoperation Rate: Results of a Multicenter Stud
      Background A multicenter, prospective, blinded study was performed to test the feasibility of using a handheld optical imaging probe for the intraoperative assessment of final surgical margins during breast-conserving surgery (BCS) and to determine the potential impact on patient outcomes. Methods Forty-six patients with early-stage breast cancer (one with bilateral disease) undergoing BCS at two study sites, the Johns Hopkins Hospital and Anne Arundel Medical Center, were enrolled in this ...
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    9. Computational high-resolution optical imaging of the living human retina

      Computational high-resolution optical imaging of the living human retina
      High-resolution in vivo imaging is of great importance for the fields of biology and medicine. The introduction of hardware-based adaptive optics (HAO) has pushed the limits of optical imaging, enabling high-resolution near diffraction-limited imaging of previously unresolvable structures 1 , 2 . In ophthalmology, when combined with optical coherence tomography, HAO has enabled a detailed three-dimensional visualization of photoreceptor distributions 3 , 4 and individual nerve fibre bundles 5 in the living human ...
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    10. Computational adaptive optics for interferometric synthetic aperture microscopy and other interferometric imaging

      Computational adaptive optics for interferometric synthetic aperture microscopy and other interferometric imaging
      Methods for correcting for aberrations in the image or three-dimensional reconstruction of a sampled region obtained by broadband interferometry. The sampled region is illuminated with a broadband beam of light, and light returned from the sample is detected, along with a reference beam, in order to derive an interference signal for pixels of a volume spanned by wavenumber and axes transverse to the beam propagation direction. An optimization procedure is ...
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    11. Feature Of The Week 5/12/13: University of Illinois at Urbana-Champaign Reports on Real-Time In Vivo Computed Optical Interferometric Tomography

      Feature Of The Week 5/12/13: University of Illinois at Urbana-Champaign Reports on Real-Time In Vivo Computed Optical Interferometric Tomography
      Real-time, high-resolution tomography over an extended field-of-view in scattering tissues remains an elusive goal for biomedical imaging. The apparent trade-off between the depth-of-field and lateral resolution in optical imaging degrades the image resolution outside the confocal region in OCT. Although a number of approaches have been utilized to overcome these limitations, many of these techniques are plagued by either high computational complexity or complicated optical setups. ISAM is a computational ...
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    12. Real-time in vivo computed optical interferometric tomography

      Real-time in vivo computed optical interferometric tomography
      High-resolution real-time tomography of scattering tissues is important for many areas of medicine and biology 1 , 2 , 3 , 4 , 5 , 6 . However, the compromise between transverse resolution and depth-of-field, in addition to low sensitivity deep in tissue, continues to impede progress towards cellular-level volumetric tomography. Computed imaging has the potential to solve these long-standing limitations. Interferometric synthetic aperture microscopy 7 , 8 , 9 is a computed imaging technique enabling high-resolution volumetric ...
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    13. Intraoperative assessment of tumor margins with a new optical imaging technology: A multi-center, randomized, blinded clinical trial

      Intraoperative assessment of tumor margins with a new optical imaging technology: A multi-center, randomized, blinded clinical trial
      Background: Partial mastectomy is the most commonly performed procedure for invasive breast cancer and is associated with a reexcision rate commonly ranging from 20% to 40% in the literature. This high rate of reexcision is associated with significant additional cost (estimated over $4,000 per reexcision) and lower quality outcomes. Optical coherence tomography (OCT) is a high-resolution imaging technology that images tissue structure with micron-scale resolution on the same scale ...
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    14. Feature Of The Week 12/9/12: University of Illinois at Urbana Champaign Researchers Extend Astronomical Guide-Star Techniques to Computational OCT Imaging

      Feature Of The Week 12/9/12: University of Illinois at Urbana Champaign Researchers Extend Astronomical Guide-Star Techniques to Computational OCT Imaging
      Researchers at the University of Illinois at Urbana-Champaign have a long history of novel work in the field of OCT and related fields. This includes the very promising area of computational adaptive optics and related methods that offer the promise of dramatically improved images in a wide variety of settings by performing post-acquisition processing of magnitude and phase data. Below is a summary of some of their recent work. Aberrations ...
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    15. Guide-star-based computational adaptive optics for broadband interferometric tomography

      Guide-star-based computational adaptive optics for broadband interferometric tomography
      We present a method for the numerical correction of optical aberrations based on indirect sensing of the scattered wavefront from point-like scatterers (guide stars) within a three-dimensional broadband interferometric tomogram. This method enables the correction of high-order monochromatic and chromatic aberrations utilizing guide stars that are revealed after numerical compensation of defocus and low-order aberrations of the optical system. Guide-star-based aberration correction in a silicone phantom with sparse sub-resolution-sized scatterers ...
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    16. Feature Of The Week 6/10/12: Computational Adaptive Optics: A New Digital Post-Processing Technique to Optimize Resolution in OCT and other Interferometric Optical Imaging Applications

      Feature Of The Week 6/10/12: Computational Adaptive Optics: A New Digital Post-Processing Technique to Optimize Resolution in OCT and other Interferometric Optical Imaging Applications
      ...volume spanning tens of Rayleigh lengths.For more information see recent Article. Courtesy of Steven Adie and Stephen Boppart from the University of Illinois at Urbana-Champaign. To share this article click Here.Referenc...
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    17. Computational adaptive optics for broadband optical interferometric tomography of biological tissue

      Computational adaptive optics for broadband optical interferometric tomography of biological tissue
      Aberrations in optical microscopy reduce image resolution and contrast, and can limit imaging depth when focusing into biological samples. Static correction of aberrations may be achieved through appropriate lens design, but this approach does not offer the flexibility of simultaneously correcting aberrations for all imaging depths, nor the adaptability to correct for sample-specific aberrations for high-quality tomographic optical imaging. Incorporation of adaptive optics (AO) methods have demonstrated considerable improvement in ...
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    18. 1-24 of 39 1 2 »
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  2. Organizations in the News

    1. (37 articles) University of Illinois at Urbana-Champaign
    2. (4 articles) Cornell University
    3. (2 articles) Institute of Applied Physics
    4. (2 articles) University of Texas at Austin
    5. (2 articles) Massachusetts General Hospital
    6. (2 articles) Duke University
    7. (2 articles) Nicolaus Copernicus University
    8. (2 articles) National Research Council Canada
    9. (1 articles) Technical University of Denmark (DTU)
    10. (1 articles) UCLA
    11. (1 articles) VU University Amsterdam
    12. (1 articles) University of Pittsburgh
  3. People in the News

    1. (17 articles) Steven G. Adie
    2. (10 articles) Nathan D. Shemonski
    3. (10 articles) Adeel Ahmad
    4. (9 articles) Daniel L. Marks
    5. (8 articles) Fredrick A. South
    6. (8 articles) Tyler S. Ralston
    7. (4 articles) Eric A. Swanson
    8. (3 articles) Andrew Cittadine
    9. (2 articles) Bertrand de Poly
    10. (2 articles) Marc D. Feldman
    11. (2 articles) James G. Fujimoto
    12. (2 articles) Claude Boccara
  4. OCT Companies in the News

    1. (5 articles) Diagnostic Photonics
    2. (2 articles) Avinger
    3. (2 articles) Oncoscope
    4. (2 articles) Tomey Corporation
    5. (2 articles) Heliotis AG
    6. (2 articles) Imalux
    7. (2 articles) Michelson Diagnostics
    8. (2 articles) Optovue
    9. (2 articles) Optopol Technology
    10. (2 articles) OptiMedica
    11. (2 articles) Tornado Spectral Systems
    12. (2 articles) Carl Zeiss Meditec