1. Articles mentioning both St. Jude Medical and Joseph M. Schmitt

    1-24 of 62 1 2 3 »
    1. Swept mode-hopping laser system, methods, and devices for frequency-domain optical coherence tomography

      Swept mode-hopping laser system, methods, and devices for frequency-domain optical coherence tomography

      In part, the invention relates to frequency-domain optical coherence tomography system. The system includes a tunable laser comprising a laser output for transmitting laser light and a laser cavity having a length L, a gain element disposed within the laser cavity; a tunable wavelength selective element disposed within the laser cavity; a reference reflector disposed outside of the laser cavity; an interferometer in optical communication with the laser output and the reference reflector, wherein the interferometer is configured to transmit a portion of the laser light to a sample and combine light scattered from the sample with light scattered from ...

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    2. Phase-lock loop-based clocking system, methods and apparatus

      Phase-lock loop-based clocking system, methods and apparatus

      In part, the invention relates to an optical coherence tomography system that includes one or more phased-locked loop circuits. In one embodiment, the phased-locked loop circuit includes a phase detector, a loop filter, and a voltage controlled oscillator wherein the phased-locked loop circuit is configured to generate a sample clock. The optical coherence tomography system can include an analog to digital converter having a sample clock input, an interferometric signal input, and a sample data output, the analog to digital converter configured to receive the sample clock and sample OCT data in response thereto. In one embodiment, the phased-locked loop ...

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    3. Miniature optical elements for fiber-optic beam shaping

      Miniature optical elements for fiber-optic beam shaping

      In part, the invention relates to optical caps having at least one lensed surface configured to redirect and focus light outside of the cap. The cap is placed over an optical fiber. Optical radiation travels through the fiber and interacts with the optical surface or optical surfaces of the cap, resulting in a beam that is either focused at a distance outside of the cap or substantially collimated. The optical elements such as the elongate caps described herein can be used with various data collection modalities such optical coherence tomography. In part, the invention relates to a lens assembly that ...

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    4. Intravascular optical coherence tomography system with pressure monitoring interface and accessories

      Intravascular optical coherence tomography system with pressure monitoring interface and accessories

      An optical coherence tomography system and method with integrated pressure measurement. In one embodiment the system includes an interferometer including: a wavelength swept laser; a source arm in communication with the wavelength swept laser; a reference arm in communication with a reference reflector; a first photodetector having a signal output; a detector arm in communication with the first photodetector, a probe interface; a sample arm in communication with a first optical connector of the probe interface; an acquisition and display system comprising: an A/D converter having a signal input in communication with the first photodetector signal output and a ...

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    5. Volumetric assessment of lesion severity with optical coherence tomography: relationship with fractional flow reserve

      Volumetric assessment of lesion severity with optical coherence tomography: relationship with fractional flow reserve

      Aims: Frequency-domain optical coherence tomography (FD-OCT) provides a rapid tomographic scan of a coronary vessel, with an accurate reconstruction of its lumen profile. An FD-OCT-based metric that corresponds more closely with physiological significance of lesions may enable more precise guidance of interventional procedures. The aim of this feasibility study was to evaluate a new method for quantifying coronary lesion severity that estimates hyperaemic flow resistance of branched vessel segments imaged by FD-OCT. Methods and results: An analytical flow model was developed that relates fractional flow reserve (FFR) to the vascular resistance ratio (VRR), a measure of blood flow resistance derived ...

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    6. Systems, Methods And Apparatus For Determining A Fractional Flow Reserve

      Systems, Methods And Apparatus For Determining A Fractional Flow Reserve

      In one aspect, the invention relates to system comprising: a processor configured to receive a first optical coherence tomography (OCT) data set obtained during a pullback of a data collection probe along a first length of a first blood vessel; determine a minimum lumen area disposed along the first length using the first OCT data set; and determine a first FFR value along the first length based on the minimum lumen area. In one embodiment, the first FFR value is an estimated FFR. In another aspect, the invention relates to a method that includes measuring, using OCT, the area of ...

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    7. Optical Coherence Tomography And Pressure Based Systems And Methods

      Optical Coherence Tomography And Pressure Based Systems And Methods

      In part, the invention relates to methods, apparatus, and systems suitable for determining a fractional flow reserve (FFR) and variations of modifications thereof One embodiment relates to a method and apparatus for obtaining a corrected FFR in a vessel having a stenosis. In one aspect, the invention relates to an apparatus for measuring corrected FFR of a vessel having a stenosis. In one embodiment, the apparatus includes a probe comprising an optical coherence tomography assembly and a pressure assembly; and a processor in communication with the optical coherence tomography assembly and the pressure assembly. In one embodiment, the pressure assembly ...

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    8. Extended coherence length megahertz FDML and its application for anterior segment imaging

      Extended coherence length megahertz FDML and its application for anterior segment imaging
      We present a 1300 nm Fourier domain mode locked (FDML) laser for optical coherence tomography (OCT) that combines both, a high 1.6 MHz wavelength sweep rate and an ultra-long instantaneous coherence length for rapid volumetric deep field imaging. By reducing the dispersion in the fiber delay line of the FDML laser, the instantaneous coherence length and hence the available imaging range is approximately quadrupled compared to previously published MHz-FDML setups, the imaging speed is increased by a factor of 16 compared to previous extended coherence length results. We present a detailed characterization of the FDML laser performance. We demonstrate ...
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    9. Structural markers observed with endoscopic 3-dimensional optical coherence tomography correlating with Barrett's esophagus radiofrequency ablation treatment response (with videos)

      Structural markers observed with endoscopic 3-dimensional optical coherence tomography correlating with Barrett's esophagus radiofrequency ablation treatment response (with videos)
      ...ond C. Adler, PhD Affiliations + LightLab Imaging Inc, St. Jude Medical Inc, Westford, Massachusetts, USA , * Joseph M. Schmitt, PhD Affiliations + LightLab Imaging Inc, St. Jude Medical Inc, Westford, Massachusetts, USA...
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    10. Comparison of Tissue Architectural Changes between Radiofrequency Ablation and Cryospray Ablation in Barrett’s Esophagus Using Endoscopic Three-Dimensional Optical Coherence Tomography

      Comparison of Tissue Architectural Changes between Radiofrequency Ablation and Cryospray Ablation in Barrett’s Esophagus Using Endoscopic Three-Dimensional Optical Coherence Tomography

      Two main nonsurgical endoscopic approaches for ablating dysplastic and early cancer lesions in the esophagus have gained popularity, namely, radiofrequency ablation (RFA) and cryospray ablation (CSA). We report a uniquely suited endoscopic and near-microscopic imaging modality, three-dimensional (3D) optical coherence tomography (OCT), to assess and compare the esophagus immediately after RFA and CSA. The maximum depths of architectural changes were measured and compared between the two treatment groups. RFA was observed to induce 230~260 

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    11. Characterization of buried glands before and after radiofrequency ablation by using 3-dimensional optical coherence tomography (with videos)

      Characterization of buried glands before and after radiofrequency ablation by using 3-dimensional optical coherence tomography (with videos)

      Background: Radiofrequency ablation (RFA) is an endoscopic technique used to eradicate Barrett's esophagus (BE). However, such ablation can commonly lead to neosquamous epithelium overlying residual BE glands not visible by conventional endoscopy and may evade detection on random biopsy samples.Objective: To demonstrate the capability of endoscopic 3-dimensional optical coherence tomography (3D-OCT) for the identification and characterization of buried glands before and after RFA therapy.Design: Cross-sectional study.Setting: Single teaching hospital.Patients: Twenty-six male and 1 female white patients with BE undergoing RFA treatment.Interventions: 3D-OCT was performed at the gastroesophageal junction in 18 patients before attaining complete ...

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    12. Neointimal tissue characteristics following sirolimus-eluting stent implantation: OCT quantitative tissue property analysis

      Neointimal tissue characteristics following sirolimus-eluting stent implantation: OCT quantitative tissue property analysis
      ...antitative tissue property analysis Jingbo Hou, Haibo Jia, Haixia Liu, Zhigang Han, Shuang Yang, Chenyang Xu, Joseph Schmitt, Shaosong Zhang, Bo Yu and Ik-Kyung Jang * Download PDF (436.2 KB) * View HTML * Permissions & ...
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    13. Intensity Noise Reduction Methods And Apparatus For Interferometric Sensing And Imaging Systems

      Intensity Noise Reduction Methods And Apparatus For Interferometric Sensing And Imaging Systems
      In part, aspects of the invention relate to methods, apparatus, and systems for intensity and/or pattern line noise reduction in a data collection system such as an optical coherence tomography system that uses an electromagnetic radiation source and interferometric principles. In one embodiment, the noise is intensity noise or line pattern noise and the source is a laser such as a swept laser. One or more attenuators responsive to one or more control signals can be used in conjunction with an analog or digital feedback network in one embodiment.
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    14. Intravascular Optical Coherence Tomography System With Pressure Monitoring Interface And Accessories

      Intravascular Optical Coherence Tomography System With Pressure Monitoring Interface And Accessories
      An optical coherence tomography system and method with integrated pressure measurement. In one embodiment the system includes an interferometer including: a wavelength swept laser; a source arm in communication with the wavelength swept laser; a reference arm in communication with a reference reflector; a first photodetector having a signal output; a detector arm in communication with the first photodetector, a probe interface; a sample arm in communication with a first optical connector of the probe interface; an acquisition and display system comprising: an A/D converter having a signal input in communication with the first photodetector signal output and a ...
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    15. Opto-acoustic imaging devices and methods

      Opto-acoustic imaging devices and methods
      In one aspect, the invention relates to a probe. The probe includes a sheath, a flexible, bi-directionally rotatable, optical subsystem positioned within the sheath, the optical subsystem comprising a transmission fiber, the optical subsystem capable of transmitting and collecting light of a predetermined range of wavelengths along a first beam having a predetermined beam size. The probe also includes an ultrasound subsystem, the ultrasound subsystem positioned within the sheath and adapted to propagate energy of a predetermined range of frequencies along a second beam having a second predetermined beam size, wherein a portion of the first and second beams overlap ...
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    16. 1-24 of 62 1 2 3 »
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  2. Organizations in the News

    1. (18 articles) Massachusetts Institute of Technology
    2. (10 articles) Harvard University
    3. (3 articles) Duke University
    4. (3 articles) University of Maryland
    5. (2 articles) University of Illinois at Urbana-Champaign
    6. (2 articles) Case Western Reserve University
    7. (2 articles) Ludwig Maximilians Universität München
    8. (2 articles) Boston University
    9. (2 articles) Cardiovascular Research Foundation
    10. (2 articles) Massachusetts General Hospital
    11. (2 articles) National Cancer Institute
    12. (2 articles) Ospedali Riuniti di Bergamo
  3. People in the News

    1. (17 articles) Desmond C. Adler
    2. (13 articles) James G. Fujimoto
    3. (12 articles) Chris L. Petersen
    4. (10 articles) Chao Zhou
    5. (10 articles) Tsung-Han Tsai
    6. (9 articles) Hiroshi Mashimo
    7. (5 articles) Craig Kelley
    8. (5 articles) Dale Flanders
    9. (4 articles) Yu Chen
    10. (3 articles) Yuankai K. Tao
    11. (2 articles) David W. Kolstad
    12. (2 articles) Wolfgang Wieser
  4. OCT Companies in the News

    1. (5 articles) Axsun Technologies
    2. (1 articles) Terumo Corporation
  5. OCT Products in the News

    1. (4 articles) Lightlab M3 Imaging Console
    2. (3 articles) Lightlab C7 XR OCT Imaging System