1. Articles mentioning both South China Normal University and Sun Yat-Sen University

    1-20 of 20
    1. The effects of electrical pulses-mediated gold and silver nanoparticles on the optical properties of ex vivo human femoral head tissue with optical coherence tomography

      The effects of electrical pulses-mediated gold and silver nanoparticles on the optical properties of ex vivo human femoral head tissue with optical coherence tomography
      This study aims to monitor and assess the penetration and accumulation of gold nanoparticles (Au NPs) or silver nanoparticles (Ag NPs) (average particle size 40 nm) and the penetration of the Au NPs or Ag NPs assisted by electrical impulses (EP) in human normal femoral head (NFH) and pathological femoral head (PFH) tissues. The results show that optical coherence tomography images can easily distinguish NFH from PFH tissues. The control ...
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    2. Redox responsive nanoparticle encapsulating black phosphorus quantum dots for cancer theranostics

      Redox responsive nanoparticle encapsulating black phosphorus quantum dots for cancer theranostics
      Effective cancer treatment puts high demands for cancer theranostics. For cancer diagnostics, optical coherence tomography (OCT) technology (including photothermal optical coherence tomography (PT-OCT)) has been widely investigated since it induces changes in optical phase transitions in tissue through environmental changes (such as temperature change for PT-OCT). In this report, redox responsive nanoparticle encapsulating black phosphorus quantum dots was developed as a robust PT-OCT agent. Briefly, black phosphorus quantum dots (BPQDs ...
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    3. Cross-correlation photothermal optical coherence tomography with high effective resolution

      Cross-correlation photothermal optical coherence tomography with high effective resolution
      We developed a cross-correlation photothermal optical coherence tomography (CC-PTOCT) system for photothermal imaging with high lateral and axial resolution. The CC-PTOCT system consists of a phase-sensitive OCT system, a modulated pumping laser, and a digital cross-correlator. The pumping laser was used to induce the photothermal effect in the sample, causing a slight phase modulation of the OCT signals. A spatial phase differentiation method was employed to reduce phase accumulation. The ...
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    4. Noninvasive monitoring of blood glucose concentration in diabetic patients with optical coherence tomography

      Noninvasive monitoring of blood glucose concentration in diabetic patients with optical coherence tomography
      Optical coherence tomography (OCT) has been used to noninvasively monitor the blood glucose concentration (BGC) in healthy subjects with good accuracy and acceptable specificity. Based on this, the paper further considered the possibility of OCT in noninvasive monitoring BGC in diabetic patients. The OCT signal slope (OCTSS) changed with variation of BGC. The correlation coefficient R between BGC and OCTSS in diabetic patients was 0.91; while the correlation coefficient ...
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    5. The diagnosis of nasopharyngeal carcinoma by optical coherence tomography (OCT)

      The diagnosis of nasopharyngeal carcinoma by optical coherence tomography (OCT)
      We have attempted to explore the intrinsic differences in the optical properties of the nasopharyngeal carcinoma (NPC) and normal tissue by optical coherence tomography (OCT). OCT imaging of normal tissue provided three layers of epithelium, lamina propria, and the brighter interface of basement membrane; while carcinomas disrupted the layered construction embedded in signal-poor images. The morphologies were consistent with histological findings. Sensitivity and specificity were 90% and 100%, respectively. This ...
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    6. Effects of titanium dioxide nanoparticles coupled with diode laser on optical properties of in vitro normal and cancerous human lung tissues studied with optical coherence tomography and diffuse reflectance spectra

      Effects of titanium dioxide nanoparticles coupled with diode laser on optical properties of in vitro normal and cancerous human lung tissues studied with optical coherence tomography and diffuse reflectance spectra
      The objective is to investigate the effects of two different sized (60 and 100 nm) titanium dioxide ( TiO 2 ) nanoparticles (NPs) penetration and accumulation in in vitro human normal lung (NL) tissue, lung squamous cell carcinoma (LSCC) tissue, and 650-nm diode laser-pretreated tissue on their optical properties studied with optical coherence tomography monitoring and diffuse reflectance (DR) spectra measurement. As with TiO 2 NPs penetrating into the tissues, the intensities ...
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    7. Influence of nanoparticles accumulation on optical properties of human normal and cancerous liver tissue in vitro estimated by OCT

      Influence of nanoparticles accumulation on optical properties of human normal and cancerous liver tissue in vitro estimated by OCT
      In this work, the potential use of nanoparticles as contrast agents by using spectral domain optical coherence tomography (SD-OCT) in liver tissue was demonstrated. Gold nanoparticles (average size of 25 and 70nm), were studied in human normal and cancerous liver tissues in vitro , respectively. Each sample was monitored with SD-OCT functional imaging for 240min. Continuous OCT monitoring showed that, after application of gold nanoparticles, the OCT signal intensities of normal ...
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    8. Monitoring of permeability of different analytes in human normal and cancerous bladder tissues invitro using optical coherence tomography

      Monitoring of permeability of different analytes in human normal and cancerous bladder tissues invitro using optical coherence tomography
      We report our preliminary results on quantification of glucose and dimethyl sulfoxide (DMSO) diffusion in normal and cancerous human bladder tissues in vitro by using a spectral domain optical coherence tomography (SD-OCT). The permeability coefficients (PCs) of a 30% aqueous solution of glucose are found to be (7.92 0.81) 10 -6 cm s -1 and (1.19 0.13) 10 -5 cm s -1 in normal and cancerous ...
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    9. In vitro assessment of effects of hyperglycemia on the optical properties of blood during coagulation using optical coherence tomography

      In vitro assessment of effects of hyperglycemia on the optical properties of blood during coagulation using optical coherence tomography
      ...iversity, Guangzhou, 510631, Guangdong Province, China Department of Surgery, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, Guangdong Province, China Key Laboratory of Optoelectronic Science...
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    10. Influence of different sized nanoparticles combined with ultrasound on the optical properties of invitro normal and cancerous human lung tissue studied with OCT and diffuse reflectance spectra

      Influence of different sized nanoparticles combined with ultrasound on the optical properties of invitro normal and cancerous human lung tissue studied with OCT and diffuse reflectance spectra
      The present study is concerned with the in vitro study of different sized titanium dioxide (TiO 2 ) nanoparticles' (NPs) penetration and accumulation in human normal lung (NL) tissue and lung adenocarcinoma tumor (LAT) tissue by the methods of continuous optical coherence tomography (OCT) monitoring and diffuse reflectance (DR) spectra measurement, and their evaluating the effects of TiO 2 NPs in two sizes (60nm and 100nm) and their combination with ultrasound ...
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    11. Effect of differently sized nanoparticles' accumulation on the optical properties of ex vivo normal and adenomatous human colon tissue with OCT imaging and diffuse reflectance spectra

      Effect of differently sized nanoparticles' accumulation on the optical properties of ex vivo normal and adenomatous human colon tissue with OCT imaging and diffuse reflectance spectra
      Using optical coherence tomography (OCT) and diffuse reflectance spectra, we investigated the dynamics of titanium dioxide (TiO 2 ) nanoparticles, of different sizes, when penetrating and accumulating in human normal colon tissue (NC) and adenomatous colon tissue (AC). The process of nanoparticle penetration and accumulation in biotissue is accompanied by changes in the optical properties of tissue. Continuous OCT monitoring showed that, after application of TiO 2 nanoparticles, the OCT signal ...
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    12. Continuous noninvasive monitoring of changes in human skin optical properties during oral intake of different sugars with optical coherence tomography

      Continuous noninvasive monitoring of changes in human skin optical properties during oral intake of different sugars with optical coherence tomography
      ...th China Normal University, Guangzhou 510631, China ^2Department of Surgery, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China ^3Key Laboratory of Optoelectronic Science and Technology fo...
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    13. Investigation of the permeability and optical clearing ability of different analytes in human normal and cancerous breast tissues by spectral domain OCT

      Investigation of the permeability and optical clearing ability of different analytes in human normal and cancerous breast tissues by spectral domain OCT
      The potential of OCT applied for early breast cancer detection attracted significant efforts. The permeability coefficients and the percentages of OCT signal enhancement for normal and cancerous breast tissues have been investigated from the experiments of 20% glucose, 40% glucose, and 20% mannitol in vitro. Obtained results indicate that the permeability coefficient in breast cancer tissue is prominently larger than that in normal breast tissue, while the optical clearing effect ...
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    14. Noninvasive blood glucose monitoring during oral intake of different sugars with optical coherence tomography in human subjects

      Noninvasive blood glucose monitoring during oral intake of different sugars with optical coherence tomography in human subjects
      The potential of OCT applied to noninvasive blood glucose monitoring has attracted significant efforts. In this work we investigated the feasibility of OCT in monitoring blood glucose during oral intake of different sugars in humans. Five groups of experiments were performed, in which different sugars were used. The OCT signal slope (OCTSS) changed with variation of blood glucose concentration (BGC). A good correlation between OCTSS and BGC was observed in ...
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    15. Assessment of the effects of ultrasound-mediated glucose on permeability of normal, benign, and cancerous human lung tissues with the Fourier-domain optical coherence tomography

      Assessment of the effects of ultrasound-mediated glucose on permeability of normal, benign, and cancerous human lung tissues with the Fourier-domain optical coherence tomography
      The objective of this study was to evaluate the effects of ultrasound-mediated analyte diffusion on permeability of normal, benign, and cancerous human lung tissue in vitro and to find more effective sonophoretic (SP) delivery in combination with the optical clearing agents (OCAs) method to distinguish normal and diseased lung tissues. The permeability coefficients of SP in combination with OCAs diffusion in lung tissue were measured with Fourier-domain optical coherence tomography ...
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    16. Quantitative measurement on optical attenuation coefficient of cell lines 5-8F and 6-10B using optical coherence tomography

      Quantitative measurement on optical attenuation coefficient of cell lines 5-8F and 6-10B using optical coherence tomography
      Oncogenesis and metastasis of tumor are difficult to detect during the clinic therapy. To explore the optical properties of tumorigenesis and metastasis in nasopharyngeal carcinoma (NPC), we assessed the NPC cell lines 5-8F and 6-10B by optical coherence tomography (OCT): first, the OCT images of the two different types of cell pellets were captured. Second, by fitting Beers law to the averaged A-scans in these OCT datasets, the attenuation coefficients ...
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    17. Synergistic effect of hyperosmotic agents and sonophoresis on breast tissue optical properties and permeability studied with spectral domain optical coherence tomography

      Synergistic effect of hyperosmotic agents and sonophoresis on breast tissue optical properties and permeability studied with spectral domain optical coherence tomography
      Hyperosmotic agents have shown great potential in tissue optical clearing. However, the low efficiency of the permeation in biological tissues seriously restricts its application in reality. The synergy of sonophoresis as a penetration enhancer and hyperosmotic agents, 20% glucose (G) and 20% mannitol (M), in optical clearing has been investigated by analyzing the variation of the attenuation coefficients and the permeability coefficients. In the sonophoresis experiments, ultrasound (US) was applied ...
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    18. Quantitative measurement of optical parameters of cell lines 5-8F and 6-10B using polarization sensitive optical coherence tomography

      Quantitative measurement of optical parameters of cell lines 5-8F and 6-10B using polarization sensitive optical coherence tomography
      ...uth China Normal University, Guangzhou 510006, China * ^b Department of Radiation Oncology, Cancer Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China * ^c Laboratory of Optical Imaging and S...
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    19. In vivo quantification of propylene glycol, glucose and glycerol diffusion in human skin with optical coherence tomography

      In vivo quantification of propylene glycol, glucose and glycerol diffusion in human skin with optical coherence tomography
      ...hua University, Shenzhen, 518055, Guangdong, China (4) Department of Surgery, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, Guangdong Province, China Received: 3 April 2010 Accepted: 2 Augus...
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    20. 1-20 of 20
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  2. Organizations in the News

    1. (12 articles) Tsinghua University
    2. (12 articles) Fujian Normal University