1. Articles mentioning both Simon Fraser University and University of Western Australia

    1-7 of 7
    1. Optimizing 3D retinal vasculature imaging in diabetic retinopathy using registration and averaging of OCT-A

      Optimizing 3D retinal vasculature imaging in diabetic retinopathy using registration and averaging of OCT-A
      High resolution visualization of optical coherence tomography (OCT) and OCT angiography (OCT-A) data is required to fully take advantage of the imaging modality's three-dimensional nature. However, artifacts induced by patient motion often degrade OCT-A data quality. This is especially true for patients with deteriorated focal vision, such as those with diabetic retinopathy (DR). We propose a novel methodology for software-based OCT-A motion correction achieved through serial acquisition, volumetric registration ...
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    2. Use of the Retinal Vascular Histology to Validate an Optical Coherence Tomography Angiography Technique

      Use of the Retinal Vascular Histology to Validate an Optical Coherence Tomography Angiography Technique
      Purpose: To determine the fidelity of optical coherence tomography angiography (OCTA) techniques by direct comparison of the retinal capillary network images obtained from the same region as imaged by OCTA and high-resolution confocal microscope. Method: Ten porcine eyes were perfused with red blood cells for OCTA image acquisition from the area centralis and then perfusion-fixed, and the vessels were labeled for confocal imaging. Two approaches involving post-processing of two-dimensional projection ...
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    3. Label‐free volumetric imaging of conjunctival collecting lymphatics ex vivo by optical coherence tomography lymphangiography

      Label‐free volumetric imaging of conjunctival collecting lymphatics ex vivo by optical coherence tomography lymphangiography
      We employ optical coherence tomography (OCT) and optical coherence microscopy (OCM) to study conjunctival lymphatics in porcine eyes ex vivo . This study is a precursor to the development of in vivo imaging of the collecting lymphatics for potentially guiding and monitoring glaucoma filtration surgery. OCT scans at 1300 nm and higher‐resolution OCM scans at 785 nm reveal the lymphatic vessels via their optical transparency. Equivalent signal characteristics are also ...
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    4. Quantitative comparisons between optical coherence tomography angiography and matched histology in the human eye

      Quantitative comparisons between optical coherence tomography angiography and matched histology in the human eye
      The aim was to quantitatively compare retinal vascular detail as seen on optical coherence tomography angiography (OCTA) and matched histology in the human eye. 13 normal human donor eyes were used. The central retinal artery was cannulated after which human packed red blood cells were perfused through the retinal vasculature. Retinal vessels were imaged using a custom-built OCTA device during red blood cell perfusion. The eye was subsequently perfused with ...
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    5. Quantitative Noninvasive Angiography of the Fovea Centralis Using Speckle Variance Optical Coherence Tomography

      Quantitative Noninvasive Angiography of the Fovea Centralis Using Speckle Variance Optical Coherence Tomography
      Purpose : To demonstrate the utility of speckle variance optical coherence tomography (svOCT), a noninvasive angiographic technique, for evaluating the foveal vasculature. Methods : Twelve normal human eyes were imaged with svOCT (1060-nm, 100-kHz custom-built system) and fluorescein angiography (FA; Topcon TRC-50DX with 5.0 megapixel resolution camera). Manual tracing techniques were used to quantify the foveal vasculature, including foveal avascular zone (FAZ) metrics (area, perimeter, greatest diameter, and lowest diameter). Reproducibility ...
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    6. In vivo optical imaging of human retinal capillary networks using speckle variance optical coherence tomography with quantitative clinico-histological correlation

      In vivo optical imaging of human retinal capillary networks using speckle variance optical coherence tomography with quantitative clinico-histological correlation
      ...phthalmology and Visual Science, The University of Western Australia, Australia * ^b Lions Eye Institute, The University of Western Australia, Perth, Australia * ^c Department of Ophthalmology and Visual Sciences, Unive...
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    7. 1-7 of 7
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    1. (3 articles) University of British Columbia
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