1. Articles mentioning both Robert A. McLaughlin and University of Western Australia

    1-24 of 74 1 2 3 »
    1. Method and system for characterising biological tissue

      Method and system for characterising biological tissue
      The present disclosure provides a method for characterizing a region of interest within or between biological tissue. The method comprises inserting at least a portion of a probe into the region of interest and directing electromagnetic radiation to the region of interest and receiving electromagnetic radiation from the region of interest using the probe in a direction that is transversal to a length of the probe. Further, the method comprises ...
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    2. Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes

      Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes
      Miniaturised optical coherence tomography (OCT) fibre-optic probes have enabled high-resolution cross-sectional imaging deep within the body. However, existing OCT fibre-optic probe fabrication methods cannot generate miniaturised freeform optics, which limits our ability to fabricate probes with both complex optical function and dimensions comparable to the optical fibre diameter. Recently, major advances in two-photon direct laser writing have enabled 3D printing of arbitrary three-dimensional micro/nanostructures with a surface roughness acceptable ...
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    3. A study of the effects of supine position and fluid intake on normal airway geometry using anatomical optical coherence tomography

      A study of the effects of supine position and fluid intake on normal airway geometry using anatomical optical coherence tomography
      Airway inhalation injuries are present in up to a third of all major burns patients and are the leading cause of mortality among this population. Understanding the mechanism of injury could minimise oedema (swelling) and airway damage. In this study, we present an anatomical OCT (aOCT) imaging system, based on a 1300-nm wavelength, high-speed, long-range MEMS-VCSEL swept laser source, for real-time volumetric imaging and assessment of inhalation injuries in airways ...
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    4. Flexible needle with integrated optical coherence tomography probe for imaging during transbronchial tissue aspiration

      Flexible needle with integrated optical coherence tomography probe for imaging during transbronchial tissue aspiration
      Transbronchial needle aspiration (TBNA) of small lesions or lymph nodes in the lung may result in nondiagnostic tissue samples. We demonstrate the integration of an optical coherence tomography (OCT) probe into a 19-gauge flexible needle for lung tissue aspiration. This probe allows simultaneous visualization and aspiration of the tissue. By eliminating the need for insertion and withdrawal of a separate imaging probe, this integrated design minimizes the risk of dislodging ...
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    5. OncoRes Medical backed by MRCF to develop innovative imaging technology for breast cancer surgery

      OncoRes Medical backed by MRCF to develop innovative imaging technology for breast cancer surgery
      ...Kennedy and Professor David Sampson from the School of Electrical, Electronic and Computer Engineering at The University of Western Australia, in collaboration with leading breast surgeon Professor Christobel Saunders an...
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    6. Investigation of optical coherence micro-elastography as a method to visualize micro-architecture in human axillary lymph nodes

      Investigation of optical coherence micro-elastography as a method to visualize micro-architecture in human axillary lymph nodes
      Background Evaluation of lymph node involvement is an important factor in detecting metastasis and deciding whether to perform axillary lymph node dissection (ALND) in breast cancer surgery. As ALND is associated with potentially severe long term morbidity, the accuracy of lymph node assessment is imperative in avoiding unnecessary ALND. The mechanical properties of malignant lymph nodes are often distinct from those of normal nodes. A method to image the micro-scale ...
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    7. In vivo label-free lymphangiography of cutaneous lymphatic vessels in human burn scars using optical coherence tomography

      In vivo label-free lymphangiography of cutaneous lymphatic vessels in human burn scars using optical coherence tomography
      We present an automated, label-free method for lymphangiography of cutaneous lymphatic vessels in humans in vivo using optical coherence tomography (OCT). This method corrects for the variation in OCT signal due to the confocal function and sensitivity fall-off of a spectral-domain OCT system and utilizes a single-scattering model to compensate for A-scan signal attenuation to enable reliable thresholding of lymphatic vessels. A segment-joining algorithm is then incorporated into the method ...
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    8. Optical coherence tomography in the assessment of acute changes in cutaneous vascular diameter induced by heat stress

      Optical coherence tomography in the assessment of acute changes in cutaneous vascular diameter induced by heat stress
      There are limited imaging technologies available that can accurately assess or provide surrogate markers of the in vivo cutaneous microvessel network in humans. In this study, we establish the use of optical coherence tomography (OCT) as a novel imaging technique to assess acute changes in cutaneous microvessel area density and diameter in humans. OCT speckle decorrelation images of the skin on the ventral side of the forearm up to a ...
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    9. Deep tissue volume imaging of birefringence through fibre-optic needle probes for the delineation of breast tumour

      Deep tissue volume imaging of birefringence through fibre-optic needle probes for the delineation of breast tumour
      Identifying tumour margins during breast-conserving surgeries is a persistent challenge. We have previously developed miniature needle probes that could enable intraoperative volume imaging with optical coherence tomography. In many situations, however, scattering contrast alone is insufficient to clearly identify and delineate malignant regions. Additional polarization-sensitive measurements provide the means to assess birefringence, which is elevated in oriented collagen fibres and may offer an intrinsic biomarker to differentiate tumour from benign ...
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    10. Investigation of optical attenuation imaging using optical coherence tomography for monitoring of scars undergoing fractional laser treatment

      Investigation of optical attenuation imaging using optical coherence tomography for monitoring of scars undergoing fractional laser treatment
      En face 2D OCT attenuation coefficient map of a treated immature scar derived from the pre-treatment (top) and the post-treatment (bottom) scans. (Vasculature (black) is masked out.) The scale bars are 0.5 mm. We demonstrate the use of the near-infrared attenuation coefficient, measured using optical coherence tomography (OCT), in longitudinal assessment of hypertrophic burn scars undergoing fractional laser treatment. The measurement method incorporates blood vessel detection by speckle decorrelation ...
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    11. Optical coherence tomography for longitudinal monitoring of vasculature in scars treated with laser fractionation - Gong - 2015 - Journal of Biophotonics - Wiley Online Library

      Optical coherence tomography for longitudinal monitoring of vasculature in scars treated with laser fractionation - Gong - 2015 - Journal of Biophotonics - Wiley Online Library
      En face optical coherence tomography vasculature images pre-treatment (top) and 20 weeks after the first laser treatment (bottom) of a mature burn scar. Arrows mark the same vessel pattern. This study presents the first in vivo longitudinal assessment of scar vasculature in ablative fractional laser treatment using optical coherence tomography (OCT). A method based on OCT speckle decorrelation was developed to visualize and quantify the scar vasculature over the treatment ...
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    12. Molecular imaging needles: dual-modality optical coherence tomography and fluorescence imaging of labeled antibodies deep in tissue

      Molecular imaging needles: dual-modality optical coherence tomography and fluorescence imaging of labeled antibodies deep in tissue
      ...iversity of Western Australia, Crawley, Australia ^4Centre for Microscopy, Characterisation & Analysis, The University of Western Australia, Crawley, Australia ^*Corresponding author: lscolaro@graduate.uwa.edu.au B...
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    13. Near video-rate optical coherence elastography by acceleration with a graphics processing unit

      Near video-rate optical coherence elastography by acceleration with a graphics processing unit
      We present a graphics processing unit (GPU)- accelerated optical coherence elastography (OCE) system capable of generating strain images (elastograms) of soft tissue at near video-rates. The system implements phase-sensitive compression OCE using a pipeline of GPU kernel functions to enable a highly parallel implementation of OCE processing using the OpenCL framework. Developed on a commercial-grade GPU and desktop computer, the system achieves a processing rate of 21 elastograms per second ...
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    14. Does smooth muscle in an intact airway undergo length adaptation during a sustained change in transmural pressure?

      Does smooth muscle in an intact airway undergo length adaptation during a sustained change in transmural pressure?
      ...3-543 DOI: 10.1152/japplphysiol.00724.2014 Thomas K. Ansell 1School of Anatomy, Physiology and Human Biology, University of Western Australia, Crawley, Western Australia, Australia; 2School of Veterinary and Life Science...
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    15. Research Associate / Research Fellow Microscope In A Needle at the University of Western Australia

      Research Associate / Research Fellow Microscope In A Needle at the University of Western Australia
      ...for its relaxed outdoor lifestyle. For more information: see http://www.obel.ee.uwa.edu.au or email A/Prof. Robert McLaughlin Robert.McLaughlin@uwa.edu.au Note that a second position is also currently being advertise...
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    16. Imaging of skin birefringence for human scar assessment using polarization-sensitive optical coherence tomography aided by vascular masking

      Imaging of skin birefringence for human scar assessment using polarization-sensitive optical coherence tomography aided by vascular masking
      ... of Surgery, Burn Injury Research Unit, 35 Stirling Highway, Crawley, Western Australia 6009, Australia. The University of Western Australia, School of Electrical, Electronic and Computer Engineering, Optical+Biomedical...
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    17. Optical coherence micro-elastography: mechanical-contrast imaging of tissue microstructure

      Optical coherence micro-elastography: mechanical-contrast imaging of tissue microstructure
      We present optical coherence micro-elastography, an improved form of compression optical coherence elastography. We demonstrate the capacity of this technique to produce en face images, closely corresponding with histology, that reveal micro-scale mechanical contrast in human breast and lymph node tissues. We use phase-sensitive, three-dimensional optical coherence tomography (OCT) to probe the nanometer-to-micrometer-scale axial displacements in tissues induced by compressive loading. Optical coherence micro-elastography incorporates common-path interferometry, weighted averaging of ...
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    18. 1-24 of 74 1 2 3 »
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  2. Organizations in the News

    1. (15 articles) Sir Charles Gairdner Hospital
    2. (2 articles) Oregon Health & Science University
    3. (2 articles) Duke University
    4. (2 articles) Polytechnique Montreal
    5. (1 articles) Massachusetts General Hospital
    6. (1 articles) Harvard University
    7. (1 articles) University of Cincinnati
    8. (1 articles) University of Auckland
    9. (1 articles) Massachusetts Institute of Technology
    10. (1 articles) University of Maryland
  3. People in the News

    1. (68 articles) David D. Sampson
    2. (21 articles) Rodney W. Kirk
    3. (19 articles) Brendan F. Kennedy
    4. (12 articles) Peter R. Eastwood
    5. (12 articles) David R. Hillman
    6. (11 articles) Andrea Curatolo
    7. (11 articles) Dirk Lorenser
    8. (11 articles) Peter B. Noble
    9. (11 articles) Julian J. Armstrong
    10. (9 articles) Loretta Scolaro
    11. (8 articles) Xiaojie Yang
    12. (8 articles) Kelsey M. Kennedy
  4. OCT Companies in the News

    1. (1 articles) Carestream Dental
    2. (1 articles) OncoRes Medical