1. Articles mentioning both Rainer A. Leitgeb and Tilman Schmoll

    1-24 of 27 1 2 »
    1. Measuring pulse-induced natural relative motions within human ocular tissue in vivo using phase-sensitive optical coherence tomography

      Measuring pulse-induced natural relative motions within human ocular tissue in vivo using phase-sensitive optical coherence tomography
      ...ions with a precision of a few micrometers per second. Keith E. O’Hara ; Tilman Schmoll ; Clemens Vass and Rainer A. Leitgeb "Measuring pulse-induced natural relative motions within human ocular tissue in vivo using ...
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    2. Measurement of Tear Film Thickness Using Ultrahigh Resolution Optical Coherence Tomography

      Measurement of Tear Film Thickness Using Ultrahigh Resolution Optical Coherence Tomography

      Purpose: To visualize the pre-corneal tear film with high resolution spectral domain optical coherence tomography, enabling quantification of tear film thickness in healthy subjects. Methods: A custom built spectral domain optical coherence tomography system comprising a broad band Ti:Sapphire laser operating at 800 nm and a high speed CCD camera with a read out rate of 47 kHz was used for measurement of pre-corneal tear film thickness. The system provides an axial resolution of 1.2 µm in tissue. A total of 26 healthy subjects were included in this study. Measurement was started immediately after blinking and averaged over ...

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    3. Ultrahigh-speed non-invasive widefield angiography

      Ultrahigh-speed non-invasive widefield angiography

      tinal and choroidal vascular imaging is an important diagnostic benefit for ocular diseases such as age-related macular degeneration. The current gold standard for vessel visualization is fluorescence angiography. We present a potential non-invasive alternative to image blood vessels based on functional Fourier domain optical coherence tomography (OCT). For OCT to compete with the field of view and resolution of angiography while maintaining motion artifacts to a minimum, ultrahigh-speed imaging has to be introduced. We employ Fourier domain mode locking swept source technology that offers high quality imaging at an A-scan rate of up to 1.68 MHz. We present retinal ...

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    4. Heart-beat-phase-coherent Doppler optical coherence tomography for measuring pulsatile ocular blood flow

      Heart-beat-phase-coherent Doppler optical coherence tomography for measuring pulsatile ocular blood flow

      We introduce a Doppler OCT (DOCT) platform that is fully synchronized with the heart-beat via a pulse oximeter. The system allows reconstructing heart-beat-phase-coherent quantitative DOCT volumes. The method is to acquire a series of DOCT volumes and to record the pulse in parallel. The heartbeat data is used for triggering the start of each DOCT volume acquisition. The recorded volume series is registered to the level of capillaries using a cross-volume registration. The information of the pulse phase is used to rearrange the tomograms in time, to obtain a series of phase coherent DOCT volumes over a pulse. We present ...

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    5. Precise Thickness Measurements of Bowman's Layer, Epithelium, and Tear Film

      Precise Thickness Measurements of Bowman's Layer, Epithelium, and Tear Film

      Purpose. To visualize corneal microstructure such as tear film, epithelium, and Bowman's layer in three dimensions with spectral domain optical coherence tomography (SDOCT) exhibiting 1.3 [mu]m axial resolution at 100,000 A-scans/s. This enables measurement of epithelial and Bowman layer thickness across an area of 8.4 mm x 8.4 mm and measuring the tear film thickness at the central cornea.Methods. We designed a high-performance SDOCT system, which uses a broad bandwidth TiSapph Laser and a high-speed complementary metal-oxide-semiconductor detector technology, providing a resolution in tissue of 1.3 [mu]m and an acquisition ...

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    6. Feature Of The Week 10/30/11: Medical University of Vienna Researchers Investigate Segmentation of Doppler OCT Signatures Using a Support-Vector Machine

      Feature Of The Week 10/30/11: Medical University of Vienna Researchers Investigate Segmentation of Doppler OCT Signatures Using a Support-Vector Machine
      Researchers from the Medical University of Vienna have been prolific contributors to the field of Optical Coherence Tomography for many years. Their pioneering work started back in the late 1980’s and early 1990’s and the group has published over 165 articles since OCT News started in late 2007 (Reference). Recently the group published interesting work on segmentation of Doppler optical coherence tomography signatures using a support-vector machine. Below is a summary of that work. Analysis of tissue perfusion offers direct access to tissue nutrition, its health, or any pathologic alterations that affect the vascular system. Doppler OCT (DOCT ...
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    7. Feature Of The Week 7/31/11: Researchers From The Medical University of Vienna Demonstrate Ultra-High Speed Fiber Based PS-OCT

      Feature Of The Week 7/31/11: Researchers From The Medical University of Vienna Demonstrate Ultra-High Speed Fiber Based PS-OCT
      Researchers at the Medical University of Vienna have been doing pioneering work in the field of OCT for over 20 years including some of the first work on low-coherence interferometric imaging of the eye, fundamental work in developing spectral domain OCT, and many other contributions. A snap shot of some of their recent work can be seen Here. Recently they published another interesting paper on ultra-high speed fiber based polarization sensitive OCT. Below is a summary of that work.Polarization sensitive (PS) OCT is a functional extension of OCT. It takes advantage of the additional polarization information carried by the ...
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    8. Single camera polarization sensitive spectral domain OCT by spatial frequency encoding

      Single camera polarization sensitive spectral domain OCT by spatial frequency encoding
      We present a polarization sensitive spectral domain optical coherence tomography system that is capable to retrieve with a single camera both retardation and optical axis orientation. The method is based on a differentiation between orthogonal polarization channels through spatial modulation introduced by an electro-optic modulator. Proof-of principle using a chromatic quarter wave plate designed for 1300nm as a sample and acquisitions of a piece of borealis, a highly birefringend plastic is provided. Results of the method for in-vivo imaging of a fingertip are presented.
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    9. Histogram-based filtering for quantitative 3D retinal angiography

      Doppler Fourier domain optical coherence tomography (D-FDOCT) can be used to visualise and measure ocular blood flow in the retina of the human eye. This has the potential to diagnose illnesses such as macula degeneration or diabetic retinopathy early on because these medical conditions cause a pathological change in the retinal vasculature and perfusion. Here we are presenting a method to separate quantitative blood flow information from static tissue. Our approach is demonstrated on retinal D-FDOCT volume scans taken at the optic nerve head (see figure) and near the fovea with a high speed CMOS-based FDOCT system. The advantage of ...
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    10. 1-24 of 27 1 2 »
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  2. Organizations in the News

    1. (27 articles) Medical University of Vienna
    2. (1 articles) Ecole Polytechnique Fédérale de Lausanne
    3. (1 articles) Ludwig Maximilian University of Munich
  3. People in the News

    1. (6 articles) Christoph K. Hitzenberger
    2. (6 articles) Erich Götzinger
    3. (6 articles) Amardeep S. G. Singh
    4. (5 articles) Michael Pircher
    5. (4 articles) Angelika Unterhuber
    6. (3 articles) Bernhard Baumann
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    12. (1 articles) Tuan Le
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    1. (2 articles) Femtolasers
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    1. (1 articles) Heidelberg Spectralis