1. Articles mentioning both Praevium Research and Thorlabs

    1-24 of 57 1 2 3 »
    1. Multi-MHz MEMS-VCSEL swept-source optical coherence tomography for endoscopic structural and angiographic imaging with miniaturized brushless motor probes

      Multi-MHz MEMS-VCSEL swept-source optical coherence tomography for endoscopic structural and angiographic imaging with miniaturized brushless motor probes
      Swept source optical coherence tomography (SS-OCT) enables volumetric imaging of subsurface structure. However, applications requiring wide fields of view (FOV), rapid imaging, and higher resolutions have been challenging because multi-MHz axial scan (A-scan) rates are needed. We describe a microelectromechanical systems vertical cavity surface-emitting laser (MEMS-VCSEL) SS-OCT technology for A-scan rates of 2.4 and 3.0 MHz. Sweep to sweep calibration and resampling are performed using dual channel acquisition ...
      Read Full Article
    2. Multi-MHz MEMS-VCSEL swept-source optical coherence tomography for endoscopic structural ...

      Multi-MHz MEMS-VCSEL swept-source optical coherence tomography for endoscopic structural ...
      ...the official views of the NIH. BP: Thorlabs, Inc. (F, E, P), VJ: Praevium Research, Inc. (F, I, E, P, S), AC: Thorlabs, Inc. (F, I, E, P, S), CB: Praevium Research, Inc. (F, E, P) 1. D. Huang, E. A. Swanson, C. Lin, J. S...
      Read Full Article
    3. Spectrally shaped tunable short-cavity laser

      Spectrally shaped tunable short-cavity laser
      A tunable source includes a short-cavity laser optimized for performance and reliability in SSOCT imaging systems, spectroscopic detection systems, and other types of detection and sensing systems. The short cavity laser has a large free spectral range cavity, fast tuning response and single transverse, longitudinal and polarization mode operation, and includes embodiments for fast and wide tuning, and optimized spectral shaping. Disclosed are both electrical and optical pumping in a ...
      Read Full Article
    4. Agile imaging system

      Agile imaging system
      An agile optical imaging system for optical coherence tomography imaging using a tunable source comprising a wavelength tunable VCL laser is disclosed. The tunable source has long coherence length and is capable of high sweep repetition rate, as well as changing the sweep trajectory, sweep speed, sweep repetition rate, sweep linearity, and emission wavelength range on the fly to support multiple modes of OCT imaging. The imaging system also offers ...
      Read Full Article
    5. Feature Of The Week 10/08/2018: Clinical Utility of Ultrahigh-Speed Endoscopic Optical Coherence Tomography in Gastroenterology

      Feature Of The Week 10/08/2018: Clinical Utility of Ultrahigh-Speed Endoscopic Optical Coherence Tomography in Gastroenterology
      Barretts esophagus (BE) surveillance is limited by biopsy sampling error. Optical coherence tomography (OCT) enables microscopic resolution, high speed, volumetric imaging and is commercially available as volumetric laser endomicroscopy (VLE, NinePoint Medical). Studies investigated cross-sectional OCT dysplasia features, including a diagnostic algorithm (VLE-DA), however, many VLE studies used ex vivo specimens due to challenges in registering biopsy with OCT. We previously demonstrated ultrahigh-speed endoscopic OCT 10x faster than commercial instruments ...
      Read Full Article
    6. Assessment of Barrett’s esophagus and dysplasia with ultrahigh-speed volumetric en face and cross-sectional optical coherence tomography

      Assessment of Barrett’s esophagus and dysplasia with ultrahigh-speed volumetric en face and cross-sectional optical coherence tomography
      Background This study aimed to evaluate the use of ultrahigh-speed volumetric en face and cross-sectional optical coherence tomography (OCT) with micromotor catheters for the in vivo assessment of Barretts esophagus and dysplasia. Methods 74 OCT datasets with correlated biopsy/endoscopic mucosal resection histology (49 nondysplastic Barretts esophagus [NDBE], 25 neoplasia) were obtained from 14 patients with Barretts esophagus and a history of dysplasia and 30 with NDBE. The associations between ...
      Read Full Article
    7. Apparatus and methods for one or more wavelength swept lasers and the detection of signals thereof

      Apparatus and methods for one or more wavelength swept lasers and the detection of signals thereof
      An optical instrument including at least a first and second wavelength swept vertical cavity laser (VCL) sources. The wavelength sweeping ranges spanned by the first and second VCL sources may differ with a region of spectral overlap. The first and second VCL sources may be operable under different modes of operation, wherein the modes of operation differ in at least one of: sweep repetition rate, sweep wavelength range, sweep center ...
      Read Full Article
    8. Cycloid scanning for wide field optical coherence tomography endomicroscopy and angiography in vivo

      Cycloid scanning for wide field optical coherence tomography endomicroscopy and angiography in vivo
      Devices that perform wide field-of-view (FOV) precision optical scanning are important for endoscopic assessment and diagnosis of luminal organ disease such as in gastroenterology. Optical scanning for in vivo endoscopic imaging has traditionally relied on one or more proximal mechanical actuators, limiting scan accuracy and imaging speed. There is a need for rapid and precise two-dimensional (2D) microscanning technologies to enable the translation of benchtop scanning microscopies to in vivo ...
      Read Full Article
    9. Widely tunable short cavity laser

      Widely tunable short cavity laser
      A tunable source includes a short-cavity laser optimized for performance and reliability in SSOCT imaging systems, spectroscopic detection systems, and other types of detection and sensing systems. The short cavity laser has a large free spectral range cavity, fast tuning response and single transverse, longitudinal and polarization mode operation, and includes embodiments for fast and wide tuning, and optimized spectral shaping. Disclosed are both electrical and optical pumping in a ...
      Read Full Article
    10. Ultrahigh-speed endoscopic optical coherence tomography and angiography enables delineation of lateral margins of endoscopic mucosal resection: a case report

      Ultrahigh-speed endoscopic optical coherence tomography and angiography enables delineation of lateral margins of endoscopic mucosal resection: a case report
      Endoscopic mucosal resection (EMR) is a common technique for resecting dysplastic lesions in Barretts esophagus (BE), stomach, and colon, 1 but precise delineation of dysplastic margins before resection and verification of complete removal after resection remain challenging. 2 , 3 Endoscopic optical coherence tomography (OCT) enables three-dimensional visualization of tissue microstructure and is commercially available as Volumetric Laser Endomicroscopy (NinePoint Medical, Bedford, MA, USA). 4 , 5 We recently developed an ultrahigh-speed ...
      Read Full Article
    11. Widely tunable swept source

      Widely tunable swept source
      A high-speed, single-mode, high power, reliable and manufacturable wavelength-tunable light source operative to emit wavelength tunable radiation over a wavelength range contained in a wavelength span between about 950 nm and about 1150 nm, including a vertical cavity laser (VCL), the VCL having a gain region with at least one compressively strained quantum well containing Indium, Gallium, and Arsenic.
      Read Full Article
    12. Endoscopic forward-viewing optical coherence tomography and angiography with MHz swept source

      Endoscopic forward-viewing optical coherence tomography and angiography with MHz swept source
      Endoscopic optical coherence tomography (OCT) instruments are mostly side viewing and rely on at least one proximal scan, thus limiting accuracy of volumetric imaging and en face visualization. Previous forward-viewing OCT devices had limited axial scan speeds. We report a forward-viewing fiber scanning 3D-OCT probe with 900 m field of view and 5 m transverse resolution, imaging at 1 MHz axial scan rate in the human gastrointestinal tract. The probe ...
      Read Full Article
    13. Cubic meter volume optical coherence tomography

      Cubic meter volume optical coherence tomography
      Optical coherence tomography (OCT) is a powerful three-dimensional (3D) imaging modality with micrometer-scale axial resolution and up to multi-GigaVoxel/s imaging speed. However, the imaging range of high-speed OCT has been limited. Here, we report 3D OCT over cubic meter volumes using a long coherence length, 1310 nm vertical-cavity surface-emitting laser and silicon photonic integrated circuit dual-quadrature receiver technology combined with enhanced signal processing. We achieved 15 m depth resolution ...
      Read Full Article
    14. Volumetric Mapping of Barrett’s Esophagus and Dysplasia With en face Optical Coherence Tomography Tethered Capsule

      Volumetric Mapping of Barrett’s Esophagus and Dysplasia With en face Optical Coherence Tomography Tethered Capsule
      To the Editor: Dysplasia in Barretts Esophagus (BE) is patchy ( 1 ) and sometimes missed by random biopsies. Optical coherence tomography (OCT) can image large areas of the esophagus; however, slow imaging speeds in earlier studies limited visualization to cross-sections. Cross-sectional OCT detected high-grade dysplasia with sensitivity / specificity of ~80 % ( 2 , 3 ). Tethered OCT capsules were demonstrated for cross-sectional imaging in unsedated screening to detect BE ( 4 , 5 ). Our group recently ...
      Read Full Article
    15. Choroidal Neovascularization Analyzed on Ultrahigh-Speed Swept-Source Optical Coherence Tomography Angiography Compared to Spectral-Domain Optical Coherence Tomography Angiography

      Choroidal Neovascularization Analyzed on Ultrahigh-Speed Swept-Source Optical Coherence Tomography Angiography Compared to Spectral-Domain Optical Coherence Tomography Angiography
      Purpose To compare visualization of choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) using an ultrahigh-speed swept-source (SS) optical coherence tomography angiography (OCTA) prototype vs a spectral-domain (SD) OCTA device. Design Comparative analysis of diagnostic instruments. Methods Patients were prospectively recruited to be imaged on SD OCT and SS OCT devices on the same day. The SD OCT device employed is the RTVue Avanti (Optovue, Inc, Fremont, California, USA ...
      Read Full Article
    16. Amplified widely tunable short cavity laser

      Amplified widely tunable short cavity laser
      An amplified tunable source includes a short-cavity laser coupled to an optical amplifier for high power, spectrally shaped operation. The short-cavity laser is coupled to a quantum well semiconductor optical amplifier with two quantum states for broadened gain. Two preferred wavelength ranges of the amplified tunable source include 1200-1400 nm and 800-1100 nm. Also disclosed is the short cavity tunable laser coupled to a fiber amplifier. Various combinations of tunable ...
      Read Full Article
    17. Tunable short cavity laser sensor

      Tunable short cavity laser sensor
      Optical systems employ a tunable source which includes a short cavity laser with a large free spectral range cavity, fast tuning response, and single transverse and longitudinal mode operation. Systems for optical spectroscopy with optimized scanning, a system for optical beam steering and a system for a tunable local oscillator are disclosed.
      Read Full Article
    18. Polarization stable widely tunable short cavity laser

      Polarization stable widely tunable short cavity laser
      A tunable source includes a short-cavity laser optimized for performance and reliability in SSOCT imaging systems, spectroscopic detection systems, and other types of detection and sensing systems. A short cavity laser with a large free spectral range cavity, fast tuning response and single transverse, longitudinal and polarization mode operation is disclosed. Methods for obtaining polarization stable operation of the tunable source are presented.
      Read Full Article
    19. Circumferential optical coherence tomography angiography imaging of the swine esophagus using a micromotor balloon catheter

      Circumferential optical coherence tomography angiography imaging of the swine esophagus using a micromotor balloon catheter
      We demonstrate a micromotor balloon imaging catheter for ultrahigh speed endoscopic optical coherence tomography (OCT) which provides wide area, circumferential structural and angiographic imaging of the esophagus without contrast agents. Using a 1310 nm MEMS tunable wavelength swept VCSEL light source, the system has a 1.2 MHz A-scan rate and ~8.5 m axial resolution in tissue. The micromotor balloon catheter enables circumferential imaging of the esophagus at 240 ...
      Read Full Article
    20. Beyond Better Clinical Care: Optical Coherence Tomography's Economic Impact

      Beyond Better Clinical Care: Optical Coherence Tomography's Economic Impact
      The optical coherence tomography (OCT) industry has grown dramatically in its first 25 years, and while the positive effects on patient clinical care are the most important measure of OCT's success, its contributions to the economy in jobs, tax receipts, and healthcare savings are also noteworthy. The field of optical coherence tomography (OCT) has grown dramatically since its discovery in the early 1990s. The commercialization and growth of OCT ...
      Read Full Article
    21. 1-24 of 57 1 2 3 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Organizations in the News

    1. (44 articles) Massachusetts Institute of Technology
    2. (9 articles) University of Erlangen
    3. (8 articles) Tufts University
    4. (6 articles) Harvard University
    5. (2 articles) Center for Ophthalmic Optics and Lasers
    6. (2 articles) Oregon Health & Science University
    7. (2 articles) Brigham and Women’s Hospital
    8. (1 articles) University of Lübeck
    9. (1 articles) Ludwig Maximilian University of Munich
    10. (1 articles) Duke University
    11. (1 articles) University of Miami
    12. (1 articles) University of Wisconsin
  3. OCT Companies in the News

    1. (5 articles) Carl Zeiss Meditec
    2. (4 articles) Visionix
    3. (4 articles) NinePoint Medical
    4. (2 articles) Leica
    5. (2 articles) Corning
    6. (2 articles) Avinger
    7. (2 articles) Excelitas Technologies
    8. (2 articles) AGFA Healthcare
    9. (2 articles) Micro-Tech
    10. (2 articles) Terumo Corporation
    11. (2 articles) Mabri.Vision
    12. (2 articles) Shenzhen Moptim Imaging Technique Co.