1. Articles mentioning both Pierre M. Lane and British Columbia Cancer Agency

    1-26 of 26
    1. Systems for optical imaging of biological tissues

      Systems for optical imaging of biological tissues
      A fiber-based polarization sensitive optical coherence tomography (PS-OCT) system uses a new polarization diversity detection (PDD) scheme and requires no active polarization modulating components. Retardation of the sample can be determined from amplitudes of arbitrarily-oriented x- and y-components of the reflected light. A hybrid custom 50/50 coupler with single-mode fiber inputs and polarization maintaining (PM) fiber outputs combines light from sample and reference arms of an interferometer. Another embodiment ...
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    2. Depth-multiplexed optical coherence tomography dual-beam manually-actuated distortion-corrected imaging (DMDI) with a micromotor catheter

      Depth-multiplexed optical coherence tomography dual-beam manually-actuated distortion-corrected imaging (DMDI) with a micromotor catheter
      We present a new micromotor catheter implementation of dual-beam manually-actuated distortion-corrected imaging (DMDI). The new catheter called a depth-multiplexed dual-beam micromotor catheter, or mDBMC, maintains the primary advantage of unlimited field-of-view distortion-corrected imaging along the catheter axis. The mDBMC uses a polarization beam splitter and cube mirror to create two beams that scan circularly with approximately constant separation at the catheter surface. This arrangement also multiplexes both imaging channels into ...
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    3. Dual-beam manually actuated distortion-corrected imaging (DMDI): two dimensional scanning with a single-axis galvanometer

      Dual-beam manually actuated distortion-corrected imaging (DMDI): two dimensional scanning with a single-axis galvanometer
      We recently demonstrated a new two-dimensional imaging paradigm called dual-beam manually actuated distortion-corrected imaging (DMDI). This technique uses a single mechanical scanner and two spatially separated beams to determine relative sample velocity and simultaneously corrects image distortions due to manual actuation. DMDI was first demonstrated using a rotating dual-beam micromotor catheter. Here, we present a new implementation of DMDI using a single axis galvanometer to scan a pair of beams ...
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    4. Correction of motion artifacts in endoscopic optical coherence tomography and autofluorescence images based on azimuthal en face image registration

      Correction of motion artifacts in endoscopic optical coherence tomography and autofluorescence images based on azimuthal en face image registration
      We present a method for the correction of motion artifacts present in two- and three-dimensionalin vivoendoscopic images produced by rotary-pullback catheters. This method can correct for cardiac/breathing-based motion artifacts and catheter-based motion artifacts such as nonuniform rotational distortion (NURD). This method assumes thaten facetissue imaging contains slowly varying structures that are roughly parallel to the pullback axis. The method reduces motion artifacts using a dynamic time warping solution through ...
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    5. Dual-beam manually-actuated distortion-corrected imaging (DMDI) with micromotor catheters

      Dual-beam manually-actuated distortion-corrected imaging (DMDI) with micromotor catheters
      e present a new paradigm for performing two-dimensional scanning called dual-beam manually-actuated distortion-corrected imaging (DMDI). DMDI operates by imaging the same object with two spatially-separated beams that are being mechanically scanned rapidly in one dimension with slower manual actuation along a second dimension. Registration of common features between the two imaging channels allows remapping of the images to correct for distortions due to manual actuation. We demonstrate DMDI using a ...
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    6. Endoscopic Doppler optical coherence tomography and autofluorescence imaging of peripheral pulmonary nodules and vasculature

      Endoscopic Doppler optical coherence tomography and autofluorescence imaging of peripheral pulmonary nodules and vasculature
      We present the first endoscopic Doppler optical coherence tomography and co-registered autofluorescence imaging (DOCT-AFI) of peripheral pulmonary nodules and vascular networks in vivo using a small 0.9 mm diameter catheter. Using exemplary images from volumetric data sets collected from 31 patients during flexible bronchoscopy, we demonstrate how DOCT and AFI offer complementary information that may increase the ability to locate and characterize pulmonary nodules. AFI offers a sensitive visual ...
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    7. Systems For Optical Imaging Of Biological Tissues

      Systems For Optical Imaging Of Biological Tissues
      A fiber-based polarization sensitive optical coherence tomography (PS-OCT) system uses a new polarization diversity detection (PDD) scheme and requires no active polarization modulating components. Retardation of the sample can be determined from amplitudes of arbitrarily-oriented x- and y-components of the reflected light. A hybrid custom 50/50 coupler with single-mode fiber inputs and polarization maintaining (PM) fiber outputs combines light from sample and reference arms of an interferometer. Another embodiment ...
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    8. Passive endoscopic polarization sensitive optical coherence tomography with completely fiber based optical components

      Passive endoscopic polarization sensitive optical coherence tomography with completely fiber based optical components
      ...s Lucas Cahill ; Anthony M. D. Lee ; Hamid Pahlevaninezhad ; Samson Ng ; Calum E. MacAulay ; Catherine Poh ; Pierre Lane; Passive endoscopic polarization sensitive optical coherence tomography with completely fiber base...
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    9. Optical coherence tomography and autofluorescence imaging of human tonsil

      Optical coherence tomography and autofluorescence imaging of human tonsil
      For the first time, we present co-registered autofluorescence imaging and optical coherence tomography (AF/OCT) of excised human palatine tonsils to evaluate the capabilities of OCT to visualize tonsil tissue components. Despite limited penetration depth, OCT can provide detailed structural information about tonsil tissue with much higher resolution than that of computed tomography, magnetic resonance imaging, and Ultrasound. Different tonsil tissue components such as epithelium, dense connective tissue, lymphoid nodules ...
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    10. A high-efficiency fiber-based imaging system for co-registered autofluorescence and optical coherence tomography

      A high-efficiency fiber-based imaging system for co-registered autofluorescence and optical coherence tomography
      We present a power-efficient fiber-based imaging system capable of co-registered autofluorescence imaging and optical coherence tomography (AF/OCT). The system employs a custom fiber optic rotary joint (FORJ) with an embedded dichroic mirror to efficiently combine the OCT and AF pathways. This three-port wavelength multiplexing FORJ setup has a throughput of more than 83% for collected AF emission, significantly more efficient compared to previously reported fiber-based methods. A custom 900 ...
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    11. Automated segmentation of porcine airway wall layers using optical coherence tomography: comparison with manual segmentation and histology

      Automated segmentation of porcine airway wall layers using optical coherence tomography: comparison with manual segmentation and histology
      ...n with manual segmentation and histology Miranda Kirby ; Anthony M. D. Lee ; Tara Candido ; Calum MacAulay ; Pierre Lane ; Stephen Lam ; Harvey O. Coxson; Automated segmentation of porcine airway wall layers using optic...
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    12. Multimodal tissue imaging: using coregistered optical tomography data to estimate tissue autofluorescence intensity change due to scattering and absorption by neoplastic epithelial cells

      Multimodal tissue imaging: using coregistered optical tomography data to estimate tissue autofluorescence intensity change due to scattering and absorption by neoplastic epithelial cells
      Autofluorescence (AF) imaging provides valuable information about the structural and chemical states of tissue that can be used for early cancer detection. Optical scattering and absorption of excitation and emission light by the epithelium can significantly affect observed tissue AF intensity. Determining the effect of epithelial attenuation on the AF intensity could lead to a more accurate interpretation of AF intensity. We propose to use optical coherence tomography coregistered with ...
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    13. In vivo lung microvasculature visualized in three dimensions using fiber-optic color Doppler optical coherence tomography

      In vivo lung microvasculature visualized in three dimensions using fiber-optic color Doppler optical coherence tomography
      For the first time, the use of fiber-optic color Doppler optical coherence tomography (CDOCT) to map in vivo the three-dimensional (3-D) vascular network of airway segments in human lungs is demonstrated. Visualizing the 3-D vascular network in the lungs may provide new opportunities for detecting and monitoring lung diseases such as asthma, chronic obstructive pulmonary disease, and lung cancer. Our CDOCT instrument employs a rotary fiber-optic probe that provides simultaneous ...
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    14. Lung vasculature imaging using speckle variance optical coherence tomography

      Lung vasculature imaging using speckle variance optical coherence tomography
      Architectural changes in and remodeling of the bronchial and pulmonary vasculature are important pathways in diseases such as asthma, chronic obstructive pulmonary disease (COPD), and lung cancer. However, there is a lack of methods that can find and examine small bronchial vasculature in vivo. Structural lung airway imaging using optical coherence tomography (OCT) has previously been shown to be of great utility in examining bronchial lesions during lung cancer screening ...
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    15. Postdoctoral Fellowship in the Integrative Oncolog Department at The Integrative Oncology Department at the British Columbia Cancer Agency

      Postdoctoral Fellowship in the Integrative Oncolog Department at The Integrative Oncology Department at the British Columbia Cancer Agency
      ...lumbia Canada V5Z 1L3 klemmen@bccancer.bc.ca Fax: 604-675-8099 The Integrative Oncology Department at the British Columbia Cancer Agency (Vancouver, BC) has an immediate opening for a Post-doctoral fellow. The Integr...
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    16. B.C. Cancer Research Center Receives CIHR Grant To Investigate High-Resolution OCT Imaging of Bronchial Epithelium

      B.C. Cancer Research Center Receives CIHR Grant To Investigate High-Resolution OCT Imaging of Bronchial Epithelium
      ...an Dollars) to investigate high-resolution OCT Imaging of Bronchial Epithelium. The principal investigator is Pierre Lane. Below is a summary of that work. Lung cancer is the most common cause of cancer death world-wide...
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    17. 1-26 of 26
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  2. Organizations in the News

    1. (6 articles) University of British Columbia
    2. (5 articles) Ryerson University
    3. (3 articles) Simon Fraser University
  3. People in the News

    1. (16 articles) Stephen Lam
    2. (12 articles) Hamid Pahlevaninezhad
    3. (5 articles) Tawimas Shaipanich
    4. (5 articles) Victor X. D. Yang
    5. (4 articles) Lucas Cahill
    6. (2 articles) Wei Zhang
    7. (2 articles) Matthew Brenner
    8. (2 articles) Harvey O. Coxson
  4. OCT Companies in the News

    1. (2 articles) St. Jude Medical