1. Articles mentioning both Philip J. Rosenfeld and University of Miami

    1-24 of 65 1 2 3 »
    1. Swept-Source OCT Angiography Identifies Choroidal Neovascularization Arising From a Choroidal Nevus

      Swept-Source OCT Angiography Identifies Choroidal Neovascularization Arising From a Choroidal Nevus
      Swept-source optical coherence tomography angiography (SS-OCTA) was used to diagnose choroidal neovascularization (CNV) arising from a choroidal nevus. A 61-year-old woman initially presented with submacular hemorrhage. She was diagnosed with neovascular age-related macular degeneration (AMD) and received three injections of bevacizumab (Avastin; Genentech, South San Francisco, CA). At a follow-up visit, SS-OCTA showed that the CNV appeared to arise from an adjacent choroidal nevus. This is the first report of ...
      Read Full Article
    2. Swept-Source OCT Angiographic Imaging of a Central Retinal Vein Occlusion During Pregnancy

      Swept-Source OCT Angiographic Imaging of a Central Retinal Vein Occlusion During Pregnancy
      To avoid fluorescein angiography in a pregnant woman diagnosed with a central retinal vein occlusion (CRVO), swept-source optical coherence tomography angiography (SS-OCTA) was performed and showed no evidence of decreased central retinal perfusion leading to the diagnosis of a nonischemic CRVO. Five months after an intravitreal injection of steroid, both her vision and the retinal appearance had returned to normal. This case demonstrates how a noninvasive, safe, 12 mm 12 ...
      Read Full Article
    3. Detection of Choriocapillaris Loss in Alport Syndrome With Swept-Source OCT Angiography

      Detection of Choriocapillaris Loss in Alport Syndrome With Swept-Source OCT Angiography
      A patient previously diagnosed with Alport Syndrome was evaluated using multimodal imaging. Optical coherence tomography (OCT) demonstrated significant thinning of the inner retina within the macula, and inner retinal cysts were found in the peripheral macula. OCT angiography demonstrated loss of the choriocapillaris. Abnormal collagen appears to have multiple deleterious effects on the retinal and choroidal structure and vasculature.
      Read Full Article
    4. Swept-Source OCT Angiography of Multiple Evanescent White Dot Syndrome With Inflammatory Retinal Pigment Epithelial Detachment

      Swept-Source OCT Angiography of Multiple Evanescent White Dot Syndrome With Inflammatory Retinal Pigment Epithelial Detachment
      A 30-year-old woman with photopsias and decreased vision was diagnosed with multiple evanescent white dot syndrome (MEWDS) with an atypical inflammatory subfoveal retinal pigment epithelial detachment (PED) and imaged using swept-source optical coherence tomography (SS-OCT) during several visits. SS-OCT imaging revealed a focal area of attenuated choriocapillaris underneath the PED. An attempt to treat the presumed macular inflammatory lesion with corticosteroids resulted in bilateral exudation consistent with central serous chorioretinopathy.
      Read Full Article
    5. Estimating Public and Patient Savings From Basic Research—A Study of Optical Coherence Tomography in Managing Antiangiogenic Therapy

      Estimating Public and Patient Savings From Basic Research—A Study of Optical Coherence Tomography in Managing Antiangiogenic Therapy
      Purpose To compare patient and Medicare savings from the use of optical coherence tomography (OCT) in guiding therapy for neovascular age-related macular degeneration (nvAMD) to the research investments made in developing OCT by the National Institutes of Health (NIH) and the National Science Foundation (NSF). Design Observational cohort study. Methods Main outcome measures were spending by Medicare as tracked by Current Procedural Terminology codes on intravitreal injections (67028), retinal OCT ...
      Read Full Article
    6. Optical coherence tomography angiography: A comprehensive review of current methods and clinical applications

      Optical coherence tomography angiography: A comprehensive review of current methods and clinical applications
      OCT has revolutionized the practice of ophthalmology over the past 1020 years. Advances in OCT technology have allowed for the creation of novel OCT-based methods. OCT-Angiography (OCTA) is one such method that has rapidly gained clinical acceptance since it was approved by the FDA in late 2016. OCTA images are based on the variable backscattering of light from the vascular and neurosensory tissue in the retina. Since the intensity and ...
      Read Full Article
    7. Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization

      Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization
      Purpose : The purpose of this study was to compare imaging of choroidal neovascularization (CNV) using swept-source (SS) and spectral-domain (SD) optical coherence tomography angiography (OCTA). Methods : Optical coherence tomography angiography was performed using a 100-kHz SS-OCT instrument and a 68-kHz SD-OCTA instrument (Carl Zeiss Meditec, Inc.). Both 3 3- and 6 6-mm 2 scans were obtained on both instruments. The 3 3-mm 2 SS-OCTA scans consisted of 300 A-scans per ...
      Read Full Article
    8. Choroidal Thickness and Choroidal Vessel Density in Nonexudative Age-Related Macular Degeneration Using Swept-Source Optical Coherence Tomography Imaging

      Choroidal Thickness and Choroidal Vessel Density in Nonexudative Age-Related Macular Degeneration Using Swept-Source Optical Coherence Tomography Imaging
      Purpose : To analyze the relationship between choroidal thickness and the distribution of choroidal blood vessels in eyes with nonexudative AMD. Methods : Eyes with a diagnosis of nonexudative AMD were imaged using a prototype 100-kHz swept-source (SS) optical coherence tomography (OCT) instrument (Carl Zeiss Meditec, Dublin, CA, USA) with a central wavelength of 1050 nm. We used an OCT cube scan pattern consisting of 512 512 A-scans over a 12 12 ...
      Read Full Article
    9. Comparison between Widefield En Face Swept-Source OCT and Conventional Multimodal Imaging for the Detection of Reticular Pseudodrusen

      Comparison between Widefield En Face Swept-Source OCT and Conventional Multimodal Imaging for the Detection of Reticular Pseudodrusen
      ...dy. Participants Patients with nonexudative AMD were prospectively enrolled in an SS-OCT imaging study at the Bascom Palmer Eye Institute. Methods On the same day, all participants underwent color, FAF, and IR fundus ima...
      Read Full Article
    10. Projection Artifact Removal Improves Visualization and Quantitation of Macular Neovascularization Imaged by Optical Coherence Tomography Angiography

      Projection Artifact Removal Improves Visualization and Quantitation of Macular Neovascularization Imaged by Optical Coherence Tomography Angiography
      Purpose To visualize and quantify the size and vessel density of macular neovascularization (MNV) using optical coherence tomography angiography (OCTA) with a projection artifact removal algorithm. Design Multicenter, observational study. Participants Subjects with MNV in 1 eye. Methods Patients were imaged using either a swept-source OCTA prototype system or a spectral-domain OCTA prototype system. The optical microangiography (OMAG) algorithm was used to generate the OCTA images. Projection artifacts from the ...
      Read Full Article
    11. OCT - catching macular degeneration before vision loss

      OCT - catching macular degeneration before vision loss
      Growing old leads to a growing number of health problems, including those that challenge our ability to see. Age-related macular degeneration (AMD) is a disease that -- until recently -- robbed the elderly of the ability to read, drive and see the faces of their loved ones. Thanks to the invention of OCT, doctors can catch the disease before vision is lost. And with the aid of new drugs, AMD can be ...
      Read Full Article
    12. SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY REVEALS CHORIOCAPILLARIS ALTERATIONS IN EYES WITH NASCENT GEOGRAPHIC ATROPHY AND DRUSEN-ASSOCIATED GEOGRAPHIC ATROPHY

      SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY REVEALS CHORIOCAPILLARIS ALTERATIONS IN EYES WITH NASCENT GEOGRAPHIC ATROPHY AND DRUSEN-ASSOCIATED GEOGRAPHIC ATROPHY
      Purpose: To investigate choriocapillaris (CC) alteration in patients with nascent geographic atrophy (nGA) and/or drusen-associated geographic atrophy (DAGA) using swept-source optical coherence tomography angiography (OCTA). Methods: A 1,050-nm wavelength, 400 kHz A-scan rate swept-source optical coherence tomography prototype was used to perform volumetric swept-source optical coherence tomography angiography over 6 mm x 6 mm fields of view in patients with nGA and/or DAGA. The resulting optical coherence ...
      Read Full Article
    13. TOWARD QUANTITATIVE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY: Visualizing Blood Flow Speeds in Ocular Pathology Using Variable Interscan Time Analysis

      TOWARD QUANTITATIVE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY: Visualizing Blood Flow Speeds in Ocular Pathology Using Variable Interscan Time Analysis
      Purpose: Currently available optical coherence tomography angiography systems provide information about blood flux but only limited information about blood flow speed. The authors develop a method for mapping the previously proposed variable interscan time analysis (VISTA) algorithm into a color display that encodes relative blood flow speed. Methods: Optical coherence tomography angiography was performed with a 1,050 nm, 400 kHz A-scan rate, swept source optical coherence tomography system using ...
      Read Full Article
    14. Optical Coherence Tomography Angiography of Chorioretinal Diseases

      Optical Coherence Tomography Angiography of Chorioretinal Diseases
      Fluorescein angiography (FA) and indocyanine green angiography (ICGA) have been the gold standard for the evaluation of retinal and choroidal vasculature in the last three decades and have revolutionized the diagnosis of retinal and choroidal vascular diseases. The advantage of these imaging modalities lies in their ability to document retinal and choroidal vasculature through the dynamic assessment of contrast transit over time in the intravascular and extravascular spaces. However, disadvantages ...
      Read Full Article
    15. Drusen Volume as a Predictor of Disease Progression in Patients With Late Age-Related Macular Degeneration in the Fellow Eye

      Drusen Volume as a Predictor of Disease Progression in Patients With Late Age-Related Macular Degeneration in the Fellow Eye
      Purpose : Increasing drusen volume was proposed to be a predictor of disease progression in age-related macular degeneration (AMD). In patients with late AMD in one eye, the fellow eyes without neovascularization are known to be at higher risk of developing exudative AMD. We evaluated the relationship between drusen volume in these fellow eyes and their progression to late AMD. Methods : A retrospective analysis included fellow eyes with drusen associated with ...
      Read Full Article
    16. Optical Coherence Tomography and the Development of Antiangiogenic Therapies in Neovascular Age-Related Macular Degeneration

      Optical Coherence Tomography and the Development of Antiangiogenic Therapies in Neovascular Age-Related Macular Degeneration
      Purpose : To explain the pivotal role optical coherence tomography (OCT) imaging had in the development of antiangiogenic therapies for the treatment of neovascular age-related macular degeneration (nvAMD). Methods : A historical literature review was combined with personal perspectives from the introduction of OCT imaging and the early clinical use of vascular endothelial growth factor (VEGF) inhibitors. Results : At the time that OCT emerged, the gold standard for imaging of nvAMD was ...
      Read Full Article
    17. Artifactual Flow Signals Within Drusen Detected by OCT Angiography

      Artifactual Flow Signals Within Drusen Detected by OCT Angiography
      BACKGROUND AND OBJECTIVE: To demonstrate possible flow artifacts when imaging drusen with optical coherence tomography angiography (OCTA). PATIENTS AND METHODS: Patients with drusen were enrolled in a prospective OCT study using the Zeiss AngioPlex OCTA instrument (Carl Zeiss Meditec, Dublin, CA). Two kinds of en face slabs were created for visualizing both structure and flow. The first slab followed the contour of Bruch's membrane. The second slab had an ...
      Read Full Article
    18. Quantitative assessment of the retinal microvasculature using optical coherence tomography angiography

      Quantitative assessment of the retinal microvasculature using optical coherence tomography angiography
      Optical coherence tomography angiography (OCTA) is clinically useful for the qualitative assessment of the macular microvasculature. However, there is a need for comprehensive quantitative tools to help objectively analyze the OCT angiograms. Few studies have reported the use of a single quantitative index to describe vessel density in OCT angiograms. In this study, we introduce a five-index quantitative analysis of OCT angiograms in an attempt to detect and assess vascular ...
      Read Full Article
    19. 1-24 of 65 1 2 3 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Organizations in the News

    1. (12 articles) University of Southern California
    2. (9 articles) University of Washington
    3. (8 articles) Massachusetts Institute of Technology
    4. (7 articles) Tufts University
    5. (6 articles) Oregon Health & Science University
    6. (5 articles) Center for Ophthalmic Optics and Lasers
    7. (5 articles) Universidade Federal de São Paulo
    8. (5 articles) Shanghai Jiao Tong University
    9. (3 articles) Centre Hospitalier Intercommunal de Créteil
    10. (3 articles) National Institutes of Health
    11. (2 articles) University of Wisconsin
    12. (2 articles) Medical University of Vienna
  3. People in the News

    1. (44 articles) Giovanni Gregori
    2. (17 articles) William J. Feuer
    3. (10 articles) Brandon J. Lujan
    4. (10 articles) Carmen A. Puliafito
    5. (9 articles) Ruikang K. Wang
    6. (9 articles) Mary K. Durbin
    7. (8 articles) James G. Fujimoto
    8. (7 articles) Jay S. Duker
    9. (6 articles) Fernando M. Penha
    10. (6 articles) Lin An
    11. (5 articles) Srinivas R. Sadda
    12. (5 articles) Bruno Lumbroso
  4. OCT Companies in the News

    1. (28 articles) Carl Zeiss Meditec
    2. (3 articles) Heidelberg Engineering
    3. (2 articles) Praevium Research
    4. (2 articles) Thorlabs
    5. (1 articles) Leica
    6. (1 articles) Bausch & Lomb
    7. (1 articles) Optovue
    8. (1 articles) Topcon Medical Systems
    9. (1 articles) Nidek