1. Articles mentioning both NYU Langone Medical Center and Joel S. Schuman

    1-25 of 25
    1. ASSESSING THE ABILITY OF PREOPERATIVE QUANTITATIVE SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY CHARACTERISTICS TO PREDICT VISUAL OUTCOME IN IDIOPATHIC MACULAR HOLE SURGERY

      ASSESSING THE ABILITY OF PREOPERATIVE QUANTITATIVE SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY CHARACTERISTICS TO PREDICT VISUAL OUTCOME IN IDIOPATHIC MACULAR HOLE SURGERY
      Purpose: To determine which spectral domain optical coherence tomography biomarkers of idiopathic macular hole (MH) correlate with the postoperative best-corrected visual acuity (BCVA) in anatomically closed MH. Methods: Retrospective analysis of spectral domain optical coherence tomography scans of 44 patients presenting with MH followed for a mean of 17 months. Widths of MH aperture, base, and ellipsoid zone disruption were calculated from presenting foveal spectral domain optical coherence tomography B-scans ...
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    2. Retinal blood flow reduction in normal-tension glaucoma with single-hemifield damage by Doppler optical coherence tomography

      Retinal blood flow reduction in normal-tension glaucoma with single-hemifield damage by Doppler optical coherence tomography
      Aims To evaluate the associations between retinal blood flow (RBF) and optical coherence tomography (OCT) structural measurements in normal-tension glaucoma (NTG) eyes with single-hemifield visual field (VF) damage by the Doppler OCT. Methods The Doppler OCT was used to measure temporal artery (TA) RBF and temporal vein (TV) RBF. Retinal nerve fibre layer thickness (RNFLT) was measured by spectral-domain OCT. Results Forty-three consecutive eyes of 43 patients with NTG with ...
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    3. In Vivo Imaging of Schlemm's Canal and Limbal Vascular Network in Mouse Using Visible-Light OCT

      In Vivo Imaging of Schlemm's Canal and Limbal Vascular Network in Mouse Using Visible-Light OCT
      Purpose : To validate the ability of visible-light optical coherence tomography (vis-OCT) in imaging the full Schlemm's canal (SC) and its surrounding limbal vascular network in mice in vivo through a compound circumlimbal scan. Methods : We developed an anterior segment vis-OCT system and a compound circumlimbal scanning method, which montages eight rotated raster scans. We calibrated the circumlimbal scan geometry using a three-dimensional printed phantom eyeball before imaging wild-type C57BL ...
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    4. Macroaneurysms Associated With Congenital Retinal Macrovessels

      Macroaneurysms Associated With Congenital Retinal Macrovessels
      Purpose: Congenital retinal macrovessels are large aberrant retinal blood vessels that cross the horizontal raphe and can traverse the central macula. Using multimodal imaging and optical coherence tomography angiography, we describe 2 cases of congenital retinal macrovessel associated with macroaneurysms. Methods: Two patients presented for evaluation and were found to have congenital retinal macrovessels associated with macroaneurysms. Color photography, optical coherence tomography, fundus autofluorescence fluorescein angiography, and optical coherence tomography ...
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    5. Estimating Visual Field Mean Deviation using Optical Coherence Tomographic Nerve Fiber Layer Measurements in Glaucoma Patients

      Estimating Visual Field Mean Deviation using Optical Coherence Tomographic Nerve Fiber Layer Measurements in Glaucoma Patients
      To construct an optical coherence tomography (OCT) nerve fiber layer (NFL) parameter that has maximal correlation and agreement with visual field (VF) mean deviation (MD). The NFL_MD parameter in dB scale was calculated from the peripapillary NFL thickness profile nonlinear transformation and VF area-weighted averaging. From the Advanced Imaging for Glaucoma study, 245 normal, 420 pre-perimetric glaucoma (PPG), and 289 perimetric glaucoma (PG) eyes were selected. NFL_MD had significantly higher ...
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    6. 3D-CNN for Glaucoma Detection Using Optical Coherence Tomography

      3D-CNN for Glaucoma Detection Using Optical Coherence Tomography
      The large size of raw 3D optical coherence tomography (OCT) volumes poses challenges for deep learning methods as it cannot be accommodated on a single GPU in its original resolution. The direct analysis of these volumes however, provides advantages such as circumventing the need for the segmentation of retinal structures. Previously, a deep learning (DL) approach was proposed for the detection of glaucoma directly from 3D OCT volumes, where the ...
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    7. Speckle reduction in visible-light optical coherence tomography using scan modulation

      Speckle reduction in visible-light optical coherence tomography using scan modulation
      We present a technique to reduce speckle in visible-light optical coherence tomography (vis-OCT) that preserves fine structural details and is robust against sample motion. Specifically, we locally modulate B-scans orthogonally to their axis of acquisition. Such modulation enables acquisition of uncorrelated speckle patterns from similar anatomical locations, which can be averaged to reduce speckle. To verify the effectiveness of speckle reduction, we performed in-vivo retinal imaging using modulated raster and ...
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    8. Inference of visual field test performance from OCT volumes using deep learning

      Inference of visual field test performance from OCT volumes using deep learning
      Visual field tests (VFT) are pivotal for glaucoma diagnosis and conducted regularly to monitor disease progression. Here we address the question to what degree aggregate VFT measurements such as Visual Field Index (VFI) and Mean Deviation (MD) can be inferred from Optical Coherence Tomography (OCT) scans of the Optic Nerve Head (ONH) or the macula. Accurate inference of VFT measurements from OCT could reduce examination time and cost. We propose ...
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    9. A feature agnostic approach for glaucoma detection in OCT volumes

      A feature agnostic approach for glaucoma detection in OCT volumes
      Optical coherence tomography (OCT) based measurements of retinal layer thickness, such as the retinal nerve fibre layer (RNFL) and the ganglion cell with inner plexiform layer (GCIPL) are commonly employed for the diagnosis and monitoring of glaucoma. Previously, machine learning techniques have relied on segmentation-based imaging features such as the peripapillary RNFL thickness and the cup-to-disc ratio. Here, we propose a deep learning technique that classifies eyes as healthy or ...
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    10. Designing visible-light optical coherence tomography towards clinics

      Designing visible-light optical coherence tomography towards clinics
      Background: The capabilities of visible-light optical coherence tomography (vis-OCT) in noninvasive anatomical and functional retinal imaging have been demonstrated by multiple groups in both rodents and healthy human subjects. Translating laboratory prototypes to an integrated clinical-environment-friendly system is required to explore the full potential of vis-OCT in disease management. Methods: We developed and optimized a portable vis-OCT system for human retinal imaging in clinical settings. We acquired raster- and circular-scan ...
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    11. Retinal optical coherence tomography image enhancement via deep learning

      Retinal optical coherence tomography image enhancement via deep learning
      Optical coherence tomography (OCT) images of the retina are a powerful tool for diagnosing and monitoring eye disease. However, they are plagued by speckle noise, which reduces image quality and reliability of assessment. This paper introduces a novel speckle reduction method inspired by the recent successes of deep learning in medical imaging. We present two versions of the network to reflect the needs and preferences of different end-users. Specifically, we ...
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    12. Classification of healthy and diseased retina using SD-OCT imaging and Random Forest algorithm

      Classification of healthy and diseased retina using SD-OCT imaging and Random Forest algorithm
      In this paper, we propose a novel classification model for automatically identifying individuals with age-related macular degeneration (AMD) or Diabetic Macular Edema (DME) using retinal features from Spectral Domain Optical Coherence Tomography (SD-OCT) images. Our classification method uses retinal features such as the thickness of the retina and the thickness of the individual retinal layers, and the volume of the pathologies such as drusen and hyper-reflective intra-retinal spots. We extract ...
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    13. The Future of Imaging in Detecting Glaucoma Progression

      The Future of Imaging in Detecting Glaucoma Progression
      Ocular imaging has been heavily incorporated into glaucoma management and provides important information that aids in the detection of disease progression. Longitudinal studies have shown that the circumpapillary retinal nerve fiber layer is an important parameter for glaucoma progression detection, whereas other studies have demonstrated that macular parameters, such as the ganglion cell inner plexiform layer and optic nerve head parameters, also are useful for progression detection. The introduction of ...
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    14. Comparison of Glaucoma Progression Detection by Optical Coherence Tomography and Visual Field

      Comparison of Glaucoma Progression Detection by Optical Coherence Tomography and Visual Field
      Purpose To compare longitudinal glaucoma progression detection using optical coherence tomography (OCT) and visual field (VF). Design Validity assessment Method We analyzed subjects with more than 5 follow-up visits (every 6 months) in the multi-center Advanced Imaging for Glaucoma Study. Fourier-domain optical coherence tomography (OCT) was used to map the thickness of the peripapillary retinal nerve fiber layer (NFL) and ganglion cell complex (GCC). OCT-based progression detection was defined as ...
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    15. Society for the Blind and Visually Impaired to Present Prestigious Leslie Dana Gold Medal at Visionary Gala in St. Louis

      Society for the Blind and Visually Impaired to Present Prestigious Leslie Dana Gold Medal at Visionary Gala in St. Louis
      ...S. Schuman MD, Professor and Chair, Department of Ophthalmology and Professor of Neuroscience and Physiology, NYU Langone Medical Center, NYU School of Medicine, at the Society’s Visionary Gala, to be held on Saturday, A...
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    16. Signal Normalization Reduces Image Appearance Disparity Among Multiple Optical Coherence Tomography Devices

      Signal Normalization Reduces Image Appearance Disparity Among Multiple Optical Coherence Tomography Devices
      Purpose : To assess the effect of the previously reported optical coherence tomography (OCT) signal normalization method on reducing the discrepancies in image appearance among spectral-domain OCT (SD-OCT) devices. Methods : Healthy eyes and eyes with various retinal pathologies were scanned at the macular region using similar volumetric scan patterns with at least two out of three SD-OCT devices at the same visit (Cirrus HD-OCT, Zeiss, Dublin, CA; RTVue, Optovue, Fremont, CA ...
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    17. Mapping in-vivo optic nerve head strains caused by intraocular and intracranial pressures

      Mapping in-vivo optic nerve head strains caused by intraocular and intracranial pressures
      Although it is well documented that abnormal levels of either intraocular (IOP) or intracranial pressure (ICP) can lead to potentially blinding conditions, such as glaucoma and papilledema, little is known about how the pressures actually affect the eye. Even less is known about potential interplay between their effects, namely how the level of one pressure might alter the effects of the other. Our goal was to measure in-vivo the pressure-induced ...
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    18. Adaptive optics optical coherence tomography in glaucoma

      Adaptive optics optical coherence tomography in glaucoma
      Since the introduction of commercial optical coherence tomography (OCT) systems, the ophthalmic imaging modality has rapidly expanded and it has since changed the paradigm of visualization of the retina and revolutionized the management and diagnosis of neuro-retinal diseases, including glaucoma. OCT remains a dynamic and evolving imaging modality, growing from time-domain OCT to the improved spectral-domain OCT, adapting novel image analysis and processing methods, and onto the newer swept-source OCT ...
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    19. New York University School of Medicine Receives NIH Grant for Novel Glaucoma Diagnostics for Structure and Function

      New York University School of Medicine Receives NIH Grant for Novel Glaucoma Diagnostics for Structure and Function
      ...H Grant for $714,891 for Novel Glaucoma Diagnostics for Structure and Function. The principal investigator is Joel Schuman. The program began in 2016 and ends in 2019. Below is a summary of the proposed work. Glaucoma i...
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    20. Optical Coherence Tomography in High Myopia

      Optical Coherence Tomography in High Myopia
      Optical coherence tomography (OCT) is a precise technology that can be used for interrogating tissue structure and function noninvasively, painlessly, and quickly using near-infrared light. At its inception, OCT was typically a tool for assessing tissue thickness. Time-domain OCT is fast enough to scan a circle centered on the optic nerve head (circumpapillary) to assess retinal nerve fiber layer (RNFL) thickness. With the development of spectral-domain OCT, volumetric (3-dimensional) scanning ...
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    21. Clinical Utility of Optical Coherence Tomography in Glaucoma

      Clinical Utility of Optical Coherence Tomography in Glaucoma
      Optical coherence tomography (OCT) has established itself as the dominant imaging modality in the management of glaucoma and retinal diseases, providing high-resolution visualization of ocular microstructures and objective quantification of tissue thickness and change. This article reviews the history of OCT imaging with a specific focus on glaucoma. We examine the clinical utility of OCT with respect to diagnosis and progression monitoring, with additional emphasis on advances in OCT technology ...
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    22. Optical Coherence Tomography in High Myopia

      Optical Coherence Tomography in High Myopia
      Optical coherence tomography (OCT) is a precise technology that can be used for interrogating tissue structure and function noninvasively, painlessly, and quickly using near-infrared light. At its inception, OCT was typically a tool for assessing tissue thickness. Time-domain OCT is fast enough to scan a circle centered on the optic nerve head (circumpapillary) to assess retinal nerve fiber layer (RNFL) thickness. With the development of spectral-domain OCT, volumetric (3-dimensional) scanning ...
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    23. Pioneering Glaucoma Expert Appointed Chair of the Department of Ophthalmology at NYU Langone Medical Center

      Pioneering Glaucoma Expert Appointed Chair of the Department of Ophthalmology at NYU Langone Medical Center
      ...d the translation of basic discoveries and inventions to clinical practice. About NYU Langone Medical Center: NYU Langone Medical Center , a world-class, patient-centered, integrated academic medical center, is one of th...
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