1. Articles mentioning both Nadia K. Waheed and Tufts University

    1-24 of 81 1 2 3 4 »
    1. A Framework for Multiscale Quantitation of Relationships Between Choriocapillaris Flow Impairment and Geographic Atrophy Growth

      A Framework for Multiscale Quantitation of Relationships Between Choriocapillaris Flow Impairment and Geographic Atrophy Growth
      Purpose To develop a multiscale analysis framework for investigating the relationships between geographic atrophy (GA) growth rate and choriocapillaris (CC) blood flow impairment using optical coherence tomography (OCT) and OCT angiography (OCTA). Design Retrospective case series. Methods We developed an OCT/OCTA analysis framework that quantitatively measures GA growth rates at global and local scales, and CC impairment at global, zonal, and local scales. A geometric GA growth model was ...
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    2. Global Analysis of Macular Choriocapillaris Perfusion in Dry Age-Related Macular Degeneration using Swept-Source Optical Coherence Tomography Angiography

      Global Analysis of Macular Choriocapillaris Perfusion in Dry Age-Related Macular Degeneration using Swept-Source Optical Coherence Tomography Angiography
      Purpose : Swept-source optical coherence tomography angiography (SS-OCTA) was used to investigate if the clinical stage of dry age-related macular degeneration (AMD) was correlated with global and regional macular choriocapillaris (CC) perfusion. Methods : In this retrospective, cross-sectional study, 6 6-mm SS-OCTA images from eyes with early, intermediate, and advanced dry AMD (56 eyes, 41 patients) were analyzed using algorithms described in the literature to assess regional flow deficit percentage (FD%) and ...
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    3. Retinal Nonperfusion Relationship to Arteries or Veins Observed on Widefield Optical Coherence Tomography Angiography in Diabetic Retinopathy

      Retinal Nonperfusion Relationship to Arteries or Veins Observed on Widefield Optical Coherence Tomography Angiography in Diabetic Retinopathy
      Purpose : To evaluate whether retinal capillary nonperfusion is found predominantly adjacent to arteries or veins in eyes with diabetic retinopathy (DR). Methods : Sixty-three eyes from 44 patients with proliferative DR (PDR) or non-PDR (NPDR) were included. Images (12 12-mm) foveal-centered optical coherence tomography (OCT) angiography (OCTA) images were taken using the Zeiss Plex Elite 9000. In 37 eyes, widefield montages with five fixation points were also obtained. A semiautomatic algorithm ...
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    4. DISTINGUISHING INTRARETINAL MICROVASCULAR ABNORMALITIES FROM RETINAL NEOVASCULARIZATION USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      DISTINGUISHING INTRARETINAL MICROVASCULAR ABNORMALITIES FROM RETINAL NEOVASCULARIZATION USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
      Purpose: With the increasing prevalence of diabetes, fast, noninvasive identification of proliferative diabetic retinopathy ( PDR ) becomes essential. This study evaluated the utility of optical coherence tomography angiography ( OCTA ) to characterize intraretinal microvascular abnormalities ( IRMA ) and retinal neovascularization (NV). Methods: Patients with severe non- PDR or PDR were imaged with fluorescein angiography and widefield swept-source OCTA (Zeiss Plex Elite 9000; Carl Zeiss Meditec, Dublin, CA). Regions suspicious for IRMA or retinal ...
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    5. Reply to Correspondence: Impact of Binarization Thresholding and Brightness/Contrast Adjustment Methodology on Optical Coherence Tomography Angiography Image Quantification

      Reply to Correspondence: Impact of Binarization Thresholding and Brightness/Contrast Adjustment Methodology on Optical Coherence Tomography Angiography Image Quantification
      We thank Dr Rabiolo and associates for their interest in our work and their correspondence.1 We also applaud them for their valuable study that examined the effect of binarization thresholding on vessel area density (VAD) in retinal vascular optical coherence tomography angiography (OCTA) images.2 In their correspondence, they highlight several points regarding our results and conclusions compared with their own findings.
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    6. Volumetric Analysis of Vascularized Serous Pigment Epithelial Detachment Progression in Neovascular Age-Related Macular Degeneration Using Optical Coherence Tomography Angiography

      Volumetric Analysis of Vascularized Serous Pigment Epithelial Detachment Progression in Neovascular Age-Related Macular Degeneration Using Optical Coherence Tomography Angiography
      Purpose : To analyze the evolution of type 1 neovascularization associated with vascularized serous pigment epithelial detachment (vsPED) using three-dimensional, volumetric, en face optical coherence tomography angiography (OCTA). Methods : This was a retrospective case series from four tertiary medical centers. OCTA images were analyzed at baseline and at the 3-, 6-, 12-, 18-, and 24-month follow-up visit when available. Visual acuity, number of injections, PED maximal height and PED area and ...
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    7. Controlling for Artifacts in Widefield Optical Coherence Tomography Angiography Measurements of Non-Perfusion Area

      Controlling for Artifacts in Widefield Optical Coherence Tomography Angiography Measurements of Non-Perfusion Area
      The recent clinical adoption of optical coherence tomography (OCT) angiography (OCTA) has enabled non-invasive, volumetric visualization of ocular vasculature at micron-scale resolutions. Initially limited to 3mm3mm and 6mm6mm fields-of-view (FOV), commercial OCTA systems now offer 12mm12mm, or larger, imaging fields. While larger FOVs promise a more complete visualization of retinal disease, they also introduce new challenges to the accurate and reliable interpretation of OCTA data. In particular, because of vignetting ...
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    8. Effect of total anti-VEGF treatment exposure on patterns of choroidal neovascularisation assessed by optical coherence tomography angiography in age-related macular degeneration: a retrospective case series

      Effect of total anti-VEGF treatment exposure on patterns of choroidal neovascularisation assessed by optical coherence tomography angiography in age-related macular degeneration: a retrospective case series
      Objective To compare clinical characteristics of patients suffering from neovascular age-related macular degeneration (nAMD) with mature and immature choroidal neovascularisation (CNV) as assessed by optical coherence tomography angiography (OCTA). To explore the effect of total anti-vascular endothelial growth factor exposure on the occurrence of mature CNV when correcting for potential confounders. Methods and analysis In this retrospective case series, we included 40 eyes of 36 patients with nAMD with CNV ...
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    9. COmbined multimodal analysis of Peripheral Retinal and mAcular circulation in Diabetic Retinopathy (COPRA Study)

      COmbined multimodal analysis of Peripheral Retinal and mAcular circulation in Diabetic Retinopathy (COPRA Study)
      Importance The relationship between peripheral retinal capillary non-perfusion with central NP is non-linear. Objective To systematically examine the relationships between the microvascular indices that are measured on OCTA and the presence and extent of peripheral non-perfusion in persons with diabetic retinopathy Design Retrospective cross-sectional study of patients with varying degrees of diabetic retinopathy ; Setting: Two large tertiary referral retina clinics Participants Eighty-two eyes of forty-five patients with varying degrees of ...
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    10. Impact of Binarization Thresholding and Brightness/Contrast Adjustment Methodology on Optical Coherence Tomography Angiography Image Quantification

      Impact of Binarization Thresholding and Brightness/Contrast Adjustment Methodology on Optical Coherence Tomography Angiography Image Quantification
      Purpose Binarization is a critical technique in OCTA image analysis, but there is no consistency in the method used in published OCTA studies. This study assessed whether differences in OCTA binarization and brightness/contrast adjustments affect quantification metrics. Design Prospective cross-sectional validity study Methods This was a single-center study examining 21 eyes of 11 healthy individuals. All eyes were imaged using the Carl Zeiss PLEX Elite 9000 swept source-OCTA, and ...
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    11. Early hydroxychloroquine retinopathy: optical coherence tomography abnormalities preceding Humphrey visual field defects

      Early hydroxychloroquine retinopathy: optical coherence tomography abnormalities preceding Humphrey visual field defects
      Background/Aims Hydroxychloroquine (HCQ) retinopathy may result in severe and irreversible vision loss, emphasising the importance of screening and early detection. The purpose of this study is to report the novel finding of early optical coherence tomography (OCT) abnormalities due to HCQ toxicity that may develop in the setting of normal Humphrey visual field (HVF) testing. Methods Data from patients with chronic HCQ exposure was obtained from seven tertiary care ...
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    12. Summary of 6th International Meeting on OCT Angiography & Advances in OCT in Rome December 2018: A Tremendous Success

      Summary of 6th International Meeting on OCT Angiography & Advances in OCT in Rome December 2018: A Tremendous Success
      ...o Lumbroso Lecture” was presented by SriniVas Sadda. Other outstanding specialists: Karl Csaky, Amani Fawzi, Nadia Waheed, Caroline Baumal, (USA), Albert Augustin, Daniel Pauleikhoff, (Germany), Ursula Schmidt-Erfurth, ...
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    13. QUANTIFICATION OF RETINAL CAPILLARY NONPERFUSION IN DIABETICS USING WIDE-FIELD OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      QUANTIFICATION OF RETINAL CAPILLARY NONPERFUSION IN DIABETICS USING WIDE-FIELD OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
      Purpose: To combine advances in high-speed, wide-field optical coherence tomography angiography ( OCTA ) with image processing methods for semiautomatic quantitative analysis of capillary nonperfusion in patients with diabetic retinopathy (DR). Methods: Sixty-eight diabetic patients (73 eyes), either without retinopathy or with different degrees of retinopathy, were prospectively recruited for volumetric swept-source OCTA imaging using 12 mm 12 mm fields centered at the fovea. A custom, semiautomatic software algorithm was used to ...
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    14. Application of Optical Coherence Tomography Angiography to Retinal Disease

      Application of Optical Coherence Tomography Angiography to Retinal Disease
      A little over two years ago, a hot new topic in retinal imaging caught the attention of ophthalmologists around the world. Optical coherence tomography angiography (OCTA), an innovative, fast, noninvasive, non-dye-based angiographic technique, quickly became a topic of great interest in major conferences and ophthalmology journals. Inquisitive minds applied the OCTA prototypes to understanding diseases such as macular degeneration, diabetic retinopathy, and glaucoma. The technologys high resolution and ability to ...
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    15. VISUALIZATION OF CHOROIDAL NEOVASCULARIZATION USING TWO COMMERCIALLY AVAILABLE SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY DEVICES

      VISUALIZATION OF CHOROIDAL NEOVASCULARIZATION USING TWO COMMERCIALLY AVAILABLE SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY DEVICES
      Purpose: To compare the sensitivity of detection and the measured size of choroidal neovascularization ( CNV ) on two commercially available spectral domain optical coherence tomography angiography ( OCTA ) devices, the Optovue RTVue XR Avanti with AngioVue and the Zeiss Cirrus HD-OCT with AngioPlex. Methods: Patients with CNV lesions were imaged consecutively on both OCTA devices on the same day of their visit. 3 3 mm and 6 6 mm scans centered at ...
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    16. A Joint Probabilistic Model for Speckle Variance, Amplitude Decorrelation and Interframe Variance (IFV) Optical Coherence Tomography Angiography

      A Joint Probabilistic Model for Speckle Variance, Amplitude Decorrelation and Interframe Variance (IFV) Optical Coherence Tomography Angiography
      Optical Coherence Tomography Angiography (OCTA) is a general method to visualize blood flow in biological tissue. Despite its good results in practice, the commonly used Amplitude Decorrelation OCTA (AD-OCTA) measure suffers from a well-understood objective function, which makes it challenging to mathematically model post processing tasks like, e.g., denoising. In this paper, a probabilistic model is developed for the three OCTA measures Speckle Variance OCTA, ADOCTA and the newly ...
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    17. Microscope-Integrated Intraoperative Ultrahigh-Speed Swept-Source Optical Coherence Tomography for Widefield Retinal and Anterior Segment Imaging

      Microscope-Integrated Intraoperative Ultrahigh-Speed Swept-Source Optical Coherence Tomography for Widefield Retinal and Anterior Segment Imaging
      BACKGROUND AND OBJECTIVE: To demonstrate the feasibility of retinal and anterior segment intraoperative widefield imaging using an ultrahigh-speed, swept-source optical coherence tomography (SS-OCT) surgical microscope attachment. PATIENTS AND METHODS: A prototype post-objective SS-OCT using a 1,050-nm wavelength, 400 kHz A-scan rate, vertical cavity surface-emitting laser (VCSEL) light source was integrated to a commercial ophthalmic surgical microscope after the objective. Each widefield OCT data set was acquired in 3 seconds ...
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    18. Long-term Progression of Type 1 Neovascularization in Age-related Macular Degeneration Using Optical Coherence Tomography Angiography

      Long-term Progression of Type 1 Neovascularization in Age-related Macular Degeneration Using Optical Coherence Tomography Angiography
      Purpose To analyze the long-term growth patterns of type 1 neovascularization (NV) in eyes with age-related macular degeneration (AMD) receiving anti-vascular endothelial growth factor (VEGF) therapy. Design : Retrospective cohort study. Methods Patients were enrolled from two eye centers and underwent optical coherence tomography angiography (OCTA) imaging with follow-up greater than 1 year. Choroidal neovascularization (CNV) was manually segmented on OCTA images and compared between time points. CNV growth was sub-divided ...
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    19. OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY TO DETECT MACULAR CAPILLARY ISCHEMIA IN PATIENTS WITH INNER RETINAL CHANGES AFTER RESOLVED DIABETIC MACULAR EDEMA

      OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY TO DETECT MACULAR CAPILLARY ISCHEMIA IN PATIENTS WITH INNER RETINAL CHANGES AFTER RESOLVED DIABETIC MACULAR EDEMA
      To compare foveal vascular anatomy between patients with and without disorganization of retinal inner layers (DRILs) after resolved diabetic macular edema using optical coherence tomography angiography (OCTA). Methods: Twenty-four eyes of 21 age- and sex-matched patients with resolved diabetic macular edema were included in this retrospective, cross-sectional study. All eyes were imaged with enhanced high-definition line or cross-line structural B scans and 3 3-mm OCTA scans. Optical coherence tomography B ...
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    20. Polypoidal Choroidal Vasculopathy on Swept-Source Optical Coherence Tomography Angiography with Variable Interscan Time Analysis

      Polypoidal Choroidal Vasculopathy on Swept-Source Optical Coherence Tomography Angiography with Variable Interscan Time Analysis
      Purpose : To use a novel optical coherence tomography angiography (OCTA) algorithm termed variable interscan time analysis (VISTA) to evaluate relative blood flow speeds in polypoidal choroidal vasculopathy (PCV). Methods : Prospective cross-sectional study enrolling patients with confirmed diagnosis of PCV. OCTA of the retina and choroid was obtained with a prototype swept-source OCT system. The acquired OCT volumes were centered on the branching vascular network (BVN) and polyps as determined by ...
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    21. Image Averaging, a Powerful Tool in Optical Coherence Tomography and OCT Angiography

      Image Averaging, a Powerful Tool in Optical Coherence Tomography and OCT Angiography
      In an elegantly conducted study, Uji et al 1 describe the association of averaging multiple en face images with the quality of the optical coherence tomography angiography (OCTA) images of the choroidal microvasculature. They demonstrate that the resulting vascular images approximate much more closely the structure of the choriocapillaris as visualized histopathologically. This is an interesting and potentially important advance in the ability of OCTA to image the choriocapillaris in ...
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    22. Atlas of Retinal OCT: Optical Coherence Tomography (Textbook)

      Atlas of Retinal OCT: Optical Coherence Tomography (Textbook)
      Optical Coherence Tomography has revolutionized todays eye care. This remarkable non-invasive scanning technology is unparalleled for aiding diagnosis of retinal disease and recording disease progression. Atlas of Retinal OCT: Optical Coherence Tomography provides expert guidance in this rapidly evolving area with high-quality, oversized images that show precise detail and assist with rapid, accurate clinical decision making.
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    23. 1-24 of 81 1 2 3 4 »
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