1. Articles mentioning both Medical University of Vienna and Cardiff University

    1-23 of 23
    1. OCT-GAN: single step shadow and noise removal from optical coherence tomography images of the human optic nerve head

      OCT-GAN: single step shadow and noise removal from optical coherence tomography images of the human optic nerve head
      Speckle noise and retinal shadows within OCT B-scans occlude important edges, fine textures and deep tissues, preventing accurate and robust diagnosis by algorithms and clinicians. We developed a single process that successfully removed both noise and retinal shadows from unseen single-frame B-scans within 10.4ms. Mean average gradient magnitude (AGM) for the proposed algorithm was 57.2% higher than current state-of-the-art, while mean peak signal to noise ratio (PSNR), contrast ...
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    2. MedLumics Names Prof. Wolfgang Drexler President of Its Scientific Advisory Board

      MedLumics Names Prof. Wolfgang Drexler President of Its Scientific Advisory Board
      ...d an international scientific reputation. In 2006, he became head of the Biomedical Imaging department at the University of Cardiff in Wales, where he had been serving as one of the members of the governing research coun...
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    3. Graphics processing unit-based dispersion encoded full-range frequency-domain optical coherence tomography

      Graphics processing unit-based dispersion encoded full-range frequency-domain optical coherence tomography
      Dispersion encoded full-range (DEFR) frequency-domain optical coherence tomography (FD-OCT) and its enhanced version, fast DEFR, utilize dispersion mismatch between sample and reference arm to eliminate the ambiguity in OCT signals caused by non-complex valued spectral measurement, thereby numerically doubling the usable information content. By iteratively suppressing asymmetrically dispersed complex conjugate artifacts of OCT-signal pulses the complex valued signal can be recovered without additional measurements, thus doubling the spatial signal range ...
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    4. Graphics processing unit based dispersion encoded full-range frequency domain OCT

      Graphics processing unit based dispersion encoded full-range frequency domain OCT
      Standard FD-OCT systems suffer from a limited useful depth range due to the inherent complex conjugate artifacts and continuous fall-off in sensitivity with distance from the zero delay. The techniques of dispersion encoded full range (DEFR) frequency-domain optical coherence tomography (FD-OCT) and its enhanced version fast DEFR use the dispersion mismatch between sample and reference arm to double the imaging depth range by iteratively suppressing complex conjugate artifacts. Previously the ...
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    5. Automated choroidal segmentation of 1060 nm OCT in healthy and pathologic eyes using a statistical model

      Automated choroidal segmentation of 1060 nm OCT in healthy and pathologic eyes using a statistical model
      A two stage statistical model based on texture and shape for fully automatic choroidal segmentation of normal and pathologic eyes obtained by a 1060 nm optical coherence tomography (OCT) system is developed. A novel dynamic programming approach is implemented to determine location of the retinal pigment epithelium/ Bruch’s membrane /choriocapillaris (RBC) boundary. The choroid–sclera interface (CSI) is segmented using a statistical model. The algorithm is robust even in ...
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    6. Feature Of The Week 10/2/11: Heritability of Ocular Component Dimensions in Mice Phenotyped using Depth-Enhanced SS-OCT

      Feature Of The Week 10/2/11: Heritability of Ocular Component Dimensions in Mice Phenotyped using Depth-Enhanced SS-OCT
      ...try and imaging of the mouse eye. J. Biomed. Opt. 15, 046004. Researchers based at Cardiff University and the Medical University of Vienna have taken advantage of the extended depth range delivered by swept source OCT to...
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    7. Mapping Choroidal and Retinal Thickness Variation in Type 2 Diabetes using Three-Dimensional 1060-nm Optical Coherence Tomography

      Mapping Choroidal and Retinal Thickness Variation in Type 2 Diabetes using Three-Dimensional 1060-nm Optical Coherence Tomography
      ...orth^1, 8. Wolfgang Drexler^3 and 9. Nik J. L. Sheen^1 1. From the ^1School of Optometry and Vision Sciences, Cardiff University, United Kingdom; 2. ^2Ludwig Boltzmann Institute for Retinology and Biomicroscopic La...
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    8. Heritability of ocular component dimensions in mice phenotyped using depth-enhanced swept source optical coherence tomography

      Heritability of ocular component dimensions in mice phenotyped using depth-enhanced swept source optical coherence tomography
      ...etry and Vision Sciences, Cardiff University, Wales, UK ^2 Center for Medical Physics Biomedical Engineering, Medical University of Vienna, Vienna, Austria ^3 Department of Ophthalmology, Chang Gung Memorial Hospital, Ta...
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    9. In vivo response of GsdmA3Dfl/+ mice to topically applied anti-psoriatic agents: effects on epidermal thickness, as determined by optical coherence tomography and H&E staining.

      In vivo response of GsdmA3Dfl/+ mice to topically applied anti-psoriatic agents: effects on epidermal thickness, as determined by optical coherence tomography and H&E staining.
      ...l of Medicine, Cardiff University, Cardiff, UK Department of Dermatology & Wound Healing, School of Medicine, Cardiff University, Cardiff, UK *Correspondence: Dr Charles M. Heard, Welsh School of Pharmacy, Cardiff Univer...
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    10. Robust segmentation of intraretinal layers in the normal human fovea using a novel statistical model based on texture and shape analysis

      Robust segmentation of intraretinal layers in the normal human fovea using a novel statistical model based on texture and shape analysis
      A novel statistical model based on texture and shape for fully automatic intraretinal layer segmentation of normal retinal tomograms obtained by a commercial 800nm optical coherence tomography (OCT) system is developed. While existing algorithms often fail dramatically due to strong speckle noise, non-optimal imaging conditions, shadows and other artefacts, the novel algorithm’s accuracy only slowly deteriorates when progressively increasing segmentation task difficulty. Evaluation against a large set of manual ...
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    11. In Vivo, In Situ Imaging of Microneedle Insertion into the Skin of Human Volunteers Using Optical Coherence Tomography

      In Vivo, In Situ Imaging of Microneedle Insertion into the Skin of Human Volunteers Using Optical Coherence Tomography
      PurposeTo gather sub-surface in situ images of microneedle-treated human skin, in vivo, using optical coherence tomography (OCT). This is the first study to utilise OCT to investigate the architectural changes that are induced in skin following microneedle application. MethodsSteel, silicon and polymer microneedle devices, with different microneedle arrangements and morphologies, were applied to two anatomical sites in human volunteers following appropriate ethical approval. A state-of-the-art ultrahigh resolution OCT imaging system ...
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    12. Three-dimensional 1060nm OCT: Choroidal thickness maps in normals and improved posterior segment visualization in cataract patients

      Three-dimensional 1060nm OCT: Choroidal thickness maps in normals and improved posterior segment visualization in cataract patients
      ... and Vision Sciences, Cardiff University, Cardiff, United Kingdom^ ^7School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom^ ^8School of Optometry and Vision Sciences, Cardiff University, C...
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    13. Fast dispersion encoded full range optical coherence tomography for retinal imaging at 800 nm and 1060 nm

      Fast dispersion encoded full range optical coherence tomography for retinal imaging at 800 nm and 1060 nm
      The dispersion mismatch between sample and reference arm in frequency-domain optical coherence tomography (OCT) can be used to iteratively suppress complex conjugate artifacts and thereby increase the imaging range. In this paper, we propose a fast dispersion encoded full range (DEFR) algorithm that detects multiple signal components per iteration. The influence of different dispersion levels on the reconstruction quality is analyzed experimentally using a multilayered scattering phantom and in vivo ...
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    14. Mutant and wild type cell chemotaxis in 3D and 4D with ultrahigh- resolution optical coherence tomography

      Mutant and wild type cell chemotaxis in 3D and 4D with ultrahigh- resolution optical coherence tomography
      Conventionally, cell chemotaxis is studied on two-dimensional (2D) transparent surfaces due to limitations in optical and image data-collection techniques. However, substrates which more closely mimic the natural environment of cells are often opaque or three-dimensional (3D). The non-invasive label-free imaging technique of frequency domain optical coherence tomography (OCT) has high axial and transverse resolution of 4m, comparatively high penetration depth and the ability to acquire volumes in a few seconds ...
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    15. Adaptive optics optical coherence tomography at 120,000 depth scans/s for non-invasive cellular phenotyping of the living human retina

      Adaptive optics optical coherence tomography at 120,000 depth scans/s for non-invasive cellular phenotyping of the living human retina
      This paper presents a successful combination of ultra-high speed (120,000 depth scans/s), ultra-high resolution optical coherence tomography with adaptive optics and an achromatizing lens for compensation of monochromatic and longitudinal chromatic ocular aberrations, respectively, allowing for non-invasive volumetric imaging in normal and pathologic human retinas at cellular resolution. The capability of this imaging system is demonstrated here through preliminary studies by probing cellular intraretinal structures that have not ...
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    16. Optical Coherence Tomography (OCT) in Ophthalmology: Introduction

      The Optical Society (OSA) is pleased to present this special issue of Optics Express on “Optical Coherence Tomography (OCT) in Ophthalmology” as part of the new Interactive Science Publishing (ISP) project. The project is being performed in collaboration with the National Library of Medicine and represents a new paradigm for the publication of digital image and large dataset information. This ISP focus issue in Optics Express contains invited articles by ...
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    17. High-speed high-resolution optical coherence tomography at 800 and 1060 nm

      Two high speed systems for spectrometer based frequency domain optical coherence tomography are presented. A device operating at 800 nm, based on the Basler Sprint CMOS camera with linerates of up to 312,000 lps and a device based on the Goodrich SUI LHD 1024 px camera at 1060 nm with 47,000 lps are applied in a clinical environment to normal subjects. The feasibility of clinical high and ultra ...
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    18. Ultrahigh resolution optical coherence tomography and pancorrection for cellular imaging of the living human retina

      Cellular in vivo visualization of the three dimensional architecture of individual human foveal cone photoreceptors is demonstrated by combining ultrahigh resolution optical coherence tomography and a novel adaptive optics modality. Isotropic resolution in the order of 2-3m, estimated from ... [Opt. Express 16, 11083-11094 (2008)]
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    19. Submicrometer axial resolution optical coherence tomography.

      Optical coherence tomography (OCT) with unprecedented submicrometer axial resolution achieved by use of a photonic crystal fiber in combination with a compact sub-10-fs Ti:sapphire laser (Femtolasers Produktions) is demonstrated for what the authors believe is the first time. The emission spectrum ranges from 550 to 950 nm (lambda(c)=725 nm , P(out)=27 mW) , resulting in a free-space axial OCT resolution of ~0.75 mum , corresponding to ~0 ...
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    20. 1-23 of 23
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  2. Organizations in the News

    1. (2 articles) University of Vienna
    2. (2 articles) Chang Gung University
    3. (2 articles) Massachusetts Institute of Technology
    4. (1 articles) University of Wisconsin
    5. (1 articles) National University of Singapore
    6. (1 articles) K. U. Leuven
    7. (1 articles) University of Pittsburgh
    8. (1 articles) University of Waterloo
    9. (1 articles) Singapore Eye Research Institute
    10. (1 articles) Ludwig Boltzmann Institute
  3. OCT Companies in the News

    1. (1 articles) Femtolasers
    2. (1 articles) Basler
    3. (1 articles) MedLumics
    4. (1 articles) Heidelberg Engineering
    5. (1 articles) UTC Aerospace Systems
    6. (1 articles) Santec
    7. (1 articles) Carl Zeiss Meditec