1. Articles mentioning both LLTech and Fabrice Harms

    1-19 of 19
    1. Dynamic full field optical coherence tomography: subcellular metabolic contrast revealed in tissues by interferometric signals temporal analysis

      Dynamic full field optical coherence tomography: subcellular metabolic contrast revealed in tissues by interferometric signals temporal analysis
      We developed a new endogenous approach to reveal subcellular metabolic contrast in fresh ex vivo tissues taking advantage of the time dependence of the full field optical coherence tomography interferometric signals. This method reveals signals linked with local activity of the endogenous scattering elements which can reveal cells where other OCT-based techniques fail or need exogenous contrast agents. We benefit from the micrometric transverse resolution of full field OCT to ...
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    2. High-resolution handheld rigid endomicroscope based on full-field optical coherence tomography

      High-resolution handheld rigid endomicroscope based on full-field optical coherence tomography
      Full-field optical coherence tomography (FF-OCT) is a powerful tool for nondestructive assessment of biological tissue, i.e., for the structural examination of tissue in depth at a cellular resolution. Mostly known as a microscopy device for ex vivo analysis, FF-OCT has also been adapted to endoscopy setups since it shows good potential for in situ cancer diagnosis and biopsy guidance. Nevertheless, all the attempts to perform endoscopic FF-OCT imaging did ...
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    3. Optical tissue sectioning using full field optical coherence tomography

      Optical tissue sectioning using full field optical coherence tomography
      According to a first aspect, the invention relates to a multimodal optical sectioning microscope (200, 400, 600) for full-field imaging of a volumic and scattering sample comprising: --a full-field OCT system for providing an image of a first section in depth of the sample comprising an illumination sub-system (201, 401, 601) and a full-field imaging interferometer with a detection sub system (208, 408, 608) and an optical conjugation device for ...
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    4. Full-field optical coherence tomography system for imaging an object

      Full-field optical coherence tomography system for imaging an object
      The present invention relates to a full-field optical coherence tomography system (300) for imaging an object (319), comprising a light source (301), a first interferometric device having means for splitting an input light beam and comprising at least a reflecting surface (307), a second interferometric device having means for splitting the spectrally modulated output beam and comprising at least a reflecting surface, a multichannel acquisition device (321), the system (300 ...
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    5. Method and device for high resolution full field interference microscopy

      Method and device for high resolution full field interference microscopy
      The invention relates to an incoherent light full field interference microscopy device for the imaging of a volumetric scattering sample (106). The device comprises an interference device (100) between a reference wave (401), produced by reflection of an incident wave by a reflective surface (105) of a reference arm of the interference device, and an object wave (402) produced by backscattering of the incident wave by a slice of the ...
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    6. Full-Field Optical Coherence Tomography of Human Donor and Pathological Corneas

      Full-Field Optical Coherence Tomography of Human Donor and Pathological Corneas
      Purpose : To evaluate the performance of a full-field optical coherence tomography (FF-OCT) system in the study of human donor and pathological corneas and assess its suitability for use in eye banks. Methods : Our study was carried out using an FF-OCT system developed for non-invasive imaging of tissue structures in depth with ultrahigh resolution (1m in all directions). Images were acquired from eight stored human donor corneas (either edematous or after ...
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    7. High resolution in-vivo imaging of skin with full field optical coherence tomography

      High resolution in-vivo imaging of skin with full field optical coherence tomography
      Full-field OCT (FFOCT) has the ability to provide en-face images with a very good axial sectioning as well as a very high transverse resolution (about 1 microns in all directions). Therefore it offers the possibility to visualize biological tissues with very high resolution both on the axial native view, and on vertical reconstructed sections. Here we investigated the potential dermatological applications of in-vivo skin imaging with FFOCT. A commercial FFOCT ...
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    8. Large Field, High Resolution Full-Field Optical Coherence Tomography: A Pre-clinical Study of Human Breast Tissue and Cancer Assessment

      Large Field, High Resolution Full-Field Optical Coherence Tomography: A Pre-clinical Study of Human Breast Tissue and Cancer Assessment
      We present a benchmark pilot study in which high-resolution Full-Field Optical Coherence Tomography (FF-OCT) was used to image human breast tissue and is evaluated to assess its ability to aid the pathologists management of intra-operative diagnoses. FF-OCT imaging safety was investigated and agreement between FF-OCT and routinely prepared histopathological images was evaluated. The compact setup used for this study provides 1 mm3 resolution and 200 mm imaging depth, and a ...
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    9. LLTECH & partners receive a €3.099M European Union CORDIS Award for Non-Invasive Optical Biopsy for Cancer Assessment using ultra high resolution FF-OCT

      LLTECH & partners receive a €3.099M European Union CORDIS Award for Non-Invasive Optical Biopsy for Cancer Assessment using ultra high resolution FF-OCT
      ...cations such as research, bio banking or intra operative sample selection. www.lltechimaging.com About LLTech LLTech is a privately owned company founded in 2007. LLTech vision is to become the leader in real time, safe,...
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    10. Optical Tissue Sectioning Using Full Field Optical Coherence Tomography

      Optical Tissue Sectioning Using Full Field Optical Coherence Tomography
      According to a first aspect, the invention relates to a multimodal optical sectioning microscope (200, 400, 600) for full-field imaging of a volumic and scattering sample comprising: - a full-field OCT system for providing an image of a first section in depth of the sample comprising an illumination sub-system (201, 401, 601) and a full-field imaging interferometer with a detection sub system (208, 408, 608) and an optical conjugation device for ...
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    11. Full-Field Optical Coherence Tomography System For Imaging An Object

      Full-Field Optical Coherence Tomography System For Imaging An Object
      The present invention relates to a full-field optical coherence tomography system (300) for imaging an object (319), comprising a light source (301), a first interferometric device having means for splitting an input light beam and comprising at least a reflecting surface (307), a second interferometric device having means for splitting the spectrally modulated output beam and comprising at least a reflecting surface, a multichannel acquisition device (321), the system (300 ...
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    12. Multimodal full-field optical coherence tomography on biological tissue: toward all optical digital pathology

      Multimodal full-field optical coherence tomography on biological tissue: toward all optical digital pathology
      Optical Coherence Tomography (OCT) is an efficient technique for in-depth optical biopsy of biological tissues, relying on interferometric selection of ballistic photons. Full-Field Optical Coherence Tomography (FF-OCT) is an alternative approach to Fourier-domain OCT (spectral or swept-source), allowing parallel acquisition of en-face optical sections. Using medium numerical aperture objective, it is possible to reach an isotropic resolution of about 1x1x1 m. After stitching a grid of acquired images, FF-OCT gives ...
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    13. 1-19 of 19
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  2. Organizations in the News

    1. (9 articles) ESPCI ParisTech
    2. (1 articles) University of Pittsburgh
  3. People in the News

    1. (14 articles) Claude Boccara
    2. (6 articles) Bertrand de Poly
    3. (6 articles) Eugénie Dalimier
    4. (6 articles) Kate Grieve
    5. (4 articles) Osnath Assayag
    6. (3 articles) Alexis Bruhat
    7. (3 articles) Anne Latrive
    8. (1 articles) Michel Pâques
    9. (1 articles) Jeffrey L. Fine