1. Articles mentioning both Junya Shite and Kobe University Graduate School of Medicine

    1-24 of 39 1 2 »
    1. Early and mid-term vascular responses to optical coherence tomography guided everolimus-eluting stent implantation in stable coronary artery disease

      Early and mid-term vascular responses to optical coherence tomography guided everolimus-eluting stent implantation in stable coronary artery disease
      Background Analysis of pooled clinical data has shown the safety of 3 months of dual antiplatelet therapy (DAPT) with everolimus-eluting cobaltchromium stents (Co-Cr EESs). This study evaluated early and mid-term vascular responses to Co-Cr EESs in patients with stable coronary artery disease (CAD). Methods The MECHANISM-Elective trial (NCT02014818) is a multicenter optical coherence tomography (OCT) registry. Enrolled patients were evaluated by OCT immediately after EES implantation (post), were prospectively allocated ...
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    2. Efficacy of the proximal optimization technique on crossover stenting in coronary bifurcation lesions in the 3D-OCT bifurcation registry

      Efficacy of the proximal optimization technique on crossover stenting in coronary bifurcation lesions in the 3D-OCT bifurcation registry
      Aim We sought to investigate the efficacy of the proximal optimization technique (POT) on crossover stenting followed by side branch (SB) dilation under optical coherence tomography guidance in a multicenter registry study. Methods and results A total of 135 bifurcation lesions in 134 patients were divided into POT (n=52) and non-POT groups (n=83). The POT was performed before SB dilatation (pre-POT; n=26), finally (final-POT; n=12), at ...
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    3. Favorable early vessel healing after everolimus-eluting stent implantation: 3-, 6-, and 12-month follow-up of optical coherence tomography

      Favorable early vessel healing after everolimus-eluting stent implantation: 3-, 6-, and 12-month follow-up of optical coherence tomography
      Background Although a prospective randomized control study revealed that 3-month dual anti-platelet therapy (DAPT) is safe and does not compromise the efficacy of everolimus-eluting stent (EES) in selected patients, detailed vessel healing at early phase after EES implantation has yet to be investigated in Japanese patients. Methods and results A total of 27 lesions in 19 patients treated with EES were serially evaluated by using optical coherence tomography (OCT) at ...
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    4. Comparison between Optical COherence tomography guidance and Angiography guidance in percutaneous coronary intervention (COCOA): Study protocol for a randomized controlled trial

      Comparison between Optical COherence tomography guidance and Angiography guidance in percutaneous coronary intervention (COCOA): Study protocol for a randomized controlled trial
      Background Optical coherence tomography (OCT) is increasingly used as an adjunct to coronary angiography for guiding percutaneous coronary intervention (PCI). The current consensus on PCI is that the large final stent area offers the best chance of a good late clinical outcome. Since OCT provides more accurate information about the coronary artery and implanted stents, OCT-guided stent implantation is expected to achieve greater stent expansion than angiography guidance alone. Therefore ...
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    5. Data on two- and three-dimensional optical coherence tomography guidance for the treatment for the bifurcation lesion

      Data on two- and three-dimensional optical coherence tomography guidance for the treatment for the bifurcation lesion
      This article comprised the data related to the research article entitled Feasibility and usefulness of three-dimensional optical coherence tomography guidance for optimal side branch treatment in coronary bifurcation stenting (Nagoshi et al., In press) [1] . In this article we reports details about two patterns of guide wire (GW) recrossing position after crossover stenting in bifurcation lesion classified with three-dimensional optical coherence tomography (3D-OCT) (Okamura et al., 2014) [2] and follow-up ...
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    6. Impact of Guidewire Recrossing Point into Stent Jailed Side Branch for Optimal Kissing Balloon Dilatation - Corelab 3D Optical Coherence Tomography Analysis

      Impact of Guidewire Recrossing Point into Stent Jailed Side Branch for Optimal Kissing Balloon Dilatation - Corelab 3D Optical Coherence Tomography Analysis
      AIMS: We investigated the influence of the guidewire recrossing point on the incidence of incomplete stent apposition (ISA) after kissing balloon dilatation (KBD), and clinical and angiographic outcome at 9 months in a prospective multicenter registry. METHODS AND RESULTS: One hundred five patients underwent single crossover stenting across the side branch (SB) and subsequent KBD. Jailing configuration of the SB orifice and the guidewire recrossing position were assessed by off-line ...
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    7. Optical Frequency Domain Imaging Versus Intravascular Ultrasound in Percutaneous Coronary Intervention (OPINION Trial) : Results From the OPINION Imaging Study

      Optical Frequency Domain Imaging Versus Intravascular Ultrasound in Percutaneous Coronary Intervention (OPINION Trial) : Results From the OPINION Imaging Study
      Objectives We sought to clarify how intravascular ultrasound (IVUS) and optical coherence tomography affect percutaneous coronary intervention (PCI) with current-generation drug-eluting stents in a pre-specified substudy of the OPINION (OPtical frequency domain imaging versus INtravascular ultrasound in percutaneous coronary interventiON) trial, a multicenter, prospective, randomized, noninferiority trial comparing optical frequency domain imaging (OFDI)-guided PCI with IVUS-guided PCI. Background The impact of these 2 imaging modalities in guiding PCI remains ...
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    8. Feasibility and usefulness of three-dimensional optical coherence tomography guidance for optimal side branch treatment in coronary bifurcation stenting

      Feasibility and usefulness of three-dimensional optical coherence tomography guidance for optimal side branch treatment in coronary bifurcation stenting
      Background For the treatment of coronary bifurcation lesions, optimal guidewire (GW) recrossing after main vessel stenting is important for good stent apposition at the side branch (SB) orifice in kissing balloon inflation (KBI). Methods We analyzed 150 bifurcation lesions treated with single stenting following KBI in the three-dimensional optical coherence tomography (3D-OCT) bifurcation registry study (201516) and a single center experience (201216). OCT examination was performed after GW recrossing to ...
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    9. Optical frequency domain imaging vs. intravascular ultrasound in percutaneous coronary intervention (OPINION trial): Study protocol for a randomized controlled trial

      Optical frequency domain imaging vs. intravascular ultrasound in percutaneous coronary intervention (OPINION trial): Study protocol for a randomized controlled trial
      Background Optical coherence tomography is becoming increasingly widespread as an adjunctive intravascular diagnostic technique in percutaneous coronary intervention (PCI), because of its ability to visualize coronary structures at high resolution. Several studies have reported that intravascular ultrasound (IVUS) guidance in PCI might be helpful to reduce subsequent stent thrombosis, restenosis, repeat revascularization, myocardial infarction, and cardiac death. The OPtical frequency domain imaging vs. INtravascular ultrasound in percutaneous coronary InterventiON (OPINION ...
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    10. Optical coherence tomography study of chronic-phase vessel healing after implantation of bare metal and paclitaxel-eluting self-expanding nitinol stents in the superficial femoral artery

      Optical coherence tomography study of chronic-phase vessel healing after implantation of bare metal and paclitaxel-eluting self-expanding nitinol stents in the superficial femoral artery
      Background This study aimed to assess chronic-phase suppression of neointimal proliferation and arterial healing following paclitaxel-coated (PTX) and bare metal stent (BMS) implantation in the superficial femoral artery using optical coherence tomography (OCT). Methods Twenty-five patients with 68 stents underwent an 8-month OCT follow-up. Besides standard OCT variables, neointimal characterization and frequencies of peri-strut low-intensity area (PLIA), macrophage accumulation, and in-stent thrombi were evaluated. Results The mean neointimal thickness was ...
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    11. Serial Optical Coherence Tomography Evaluation at 6, 12, and 24 months Following Biolimus A9-Eluting Biodegradable Polymer Coated Stent Implantation

      Serial Optical Coherence Tomography Evaluation at 6, 12, and 24 months Following Biolimus A9-Eluting Biodegradable Polymer Coated Stent Implantation
      Background Nobori is a biolimus A9-eluting stent (BES) featured with a biodegradable polymer coated on the abluminal side only. We previously reported that favorable vessel healing was achieved at 6-12 months after BES implantation. However, detailed long-term vessel reaction post-BES deployment is unclear. Methods Twenty-two BESs were serially evaluated by optical coherence tomography (OCT) at 6, 12, and 24 months post-stenting. Average neointimal thickness, uncovered struts and neointimal unevenness score ...
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    12. Optical Coherence Tomography and Histopathology Assessment After Implantation of First- and Second-Generation Drug-Eluting Stents in a Porcine Coronary Model

      Optical Coherence Tomography and Histopathology Assessment After Implantation of First- and Second-Generation Drug-Eluting Stents in a Porcine Coronary Model
      Background: This study directly compared optical coherence tomography (OCT) and histopathology for the assessment of vascular response to first- and second-generation drug-eluting stents. Methods and Results: Sirolimus-, everolimus-, and biolimus-eluting stents (SES, EES, and BES, respectively) were randomly implanted into the coronary arteries of 12 porcine. OCT was conducted after implantation: at 1, 3, and 6 months; histopathology was assessed at 3 and 6 months. At 1-month OCT, EES had ...
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    13. Stabilizing effect of combined eicosapentaenoic acid and statin therapy on coronary thin-cap fibroatheroma

      Stabilizing effect of combined eicosapentaenoic acid and statin therapy on coronary thin-cap fibroatheroma
      Background The addition of highly purified eicosapentaenoic acid (EPA) to statin therapy prevents cardiovascular events. However, the impact of this treatment on vulnerable plaques remains unclear. The aim of this study was to assess the impact of adding EPA to a standard statin therapy on vulnerable plaques by serial optical coherence tomography (OCT). Methods Forty-nine non-culprit thin-cap fibroatheroma (TCFA) lesions in 30 patients with untreated dyslipidemia were included. Patients were ...
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    14. Analysis of Long-term Arterial Healing Following Implantation of Different Types of Stents by Optical Coherence Tomography

      Analysis of Long-term Arterial Healing Following Implantation of Different Types of Stents by Optical Coherence Tomography
      Background Although drug-eluting stents have significantly reduced the mid-term incidence of target lesion revascularization, however, in vivo studies on long-term vessel healing of sirolimus-eluting and paclitaxel-eluting stents (SES and PES) are limited. So the aim of this study was to compare long-term arterial healing in SES and PES. Methods We evaluated 27 SES (23 patients) and 21 PES (20 patients) by serial optical coherence tomography (OCT) at 6 months (mid-phase ...
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    15. Neoatherosclerosis and Mural Thrombus Detection After Sirolimus-Eluting Stent Implantation

      Neoatherosclerosis and Mural Thrombus Detection After Sirolimus-Eluting Stent Implantation
      Background: Although both optical coherence tomography (OCT) and angioscopy are robust tools for detecting intrastent thrombi and neoatherosclerosis in vivo, whether OCT findings are comparable with angioscopy findings remains unclear. Methods and Results: 22 patients presenting with de novo lesions underwent 26 sirolimus-eluting stent (SES) implantations, with follow-up OCT and angioscopy at 10 months post-implantation for segmental assessment of the proximal, mid-, and distal SES segments (66 segments). The mean ...
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    16. Optical coherence tomography and histopathological assessment of delayed arterial healing after drug-eluting stent implant in a pig coronary model

      Optical coherence tomography and histopathological assessment of delayed arterial healing after drug-eluting stent implant in a pig coronary model
      Background Delayed healing, such as persistent inflammation and fibrin deposition, and vascular dysfunction after drug-eluting stent has been reported. Histological validation of coronary optical coherence tomography (OCT) morphology has not yet been done. Methods Sirolimus eluting stents (SES, n = 8) and bare metal stents (BMS n = 8) were implanted in pig coronary arteries. One month after implantation, an acetylcholine challenge test and OCT were performed. The OCT texture pattern of ...
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    17. Potential Benefit of Final Kissing Balloon Inflation After Single Stenting for the Treatment of Bifurcation Lesions – Insights From Optical Coherence Tomography Observation

      Potential Benefit of Final Kissing Balloon Inflation After Single Stenting for the Treatment of Bifurcation Lesions – Insights From Optical Coherence Tomography Observation
      Background: Treatment of coronary bifurcation lesions using a single stenting strategy is preferable over that using a 2-stent technique. The benefit of final kissing inflation (FKI), however, has not been established. Methods and Results: Seventy-two patients (76 lesions) with true bifurcation lesions treated with a single drug-eluting stent with FKI (n=33 lesions) or without FKI (non-FKI, n=43 lesions) were enrolled in this study. Optical coherence tomography (OCT) was ...
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    18. Natural consequence of post-intervention stent malapposition, thrombus, tissue prolapse, and dissection assessed by optical coherence tomography at mid-term follow-up

      Natural consequence of post-intervention stent malapposition, thrombus, tissue prolapse, and dissection assessed by optical coherence tomography at mid-term follow-up
      ...shi Hiranuma and 15. Ken-ichi Hirata 1. Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, Hyogo 650-0017, Japan 1. ↵*Cor...
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    19. Qualitative and Quantitative Assessment of Stent Restenosis by Optical Coherence Tomography

      Qualitative and Quantitative Assessment of Stent Restenosis by Optical Coherence Tomography
      We hypothesized that the tissue components of in-stent restenosis (ISR) might differ between drug-eluting stents (DES) and bare-metal stents (BMS) and that these differences could be distinguished by qualitative and quantitative optical coherence tomography (OCT) analyses. Methods and Results: One-hundred and twenty-two initial ISR lesions (sirolimus-eluting stents: n=28; paclitaxel-eluting stents: n=51; BMS: n=43) were evaluated with OCT. Based on their OCT appearance, the lesions were classified as ...
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    20. Effect of Cytochrome P450 2C19 Polymorphism on Target Lesion Outcome After Drug-Eluting Stent Implantation in Japanese Patients Receiving Clopidogrel

      Effect of Cytochrome P450 2C19 Polymorphism on Target Lesion Outcome After Drug-Eluting Stent Implantation in Japanese Patients Receiving Clopidogrel
      Background:Cytochrome P450 (CYP) 2C19 polymorphism is associated with reduced responsiveness to clopidogrel and poor clinical outcome after drug-eluting stent (DES) implantation, but its contribution to lesion outcome after DES implantation is unclear. Methods and Results:The study included 160 Japanese patients who received clopidogrel and underwent DES implantation with follow-up angiography. Patients were divided into 3 groups by CYP2C19 polymorphism: extensive metabolizers (EM), intermediate metabolizers (IM), and poor metabolizers ...
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    21. Ability of Optical Coherence Tomography to Visualize the Entry Port of Spontaneous Coronary Artery Dissection

      Ability of Optical Coherence Tomography to Visualize the Entry Port of Spontaneous Coronary Artery Dissection
      A 51-year-old man was admitted to a local hospital with sudden onset of severe back pain diagnosed as acute type A aortic dissection on contrast computed tomography (CT). The patient was transferred to Kobe University Hospital and underwent total arch replacement. He had no cardiac risk factors except for obesity, and no connective tissue disorders or clinical features of Marfan syndrome. From the intraoperative findings, the entry of the aortic ...
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    22. Optical Coherence Tomography for Patient-specific 3D Artery Reconstruction and Evaluation of Wall Shear Stress in a Left Circumflex Coronary Artery

      Optical Coherence Tomography for Patient-specific 3D Artery Reconstruction and Evaluation of Wall Shear Stress in a Left Circumflex Coronary Artery
      ...ry Artery Laura M. Ellwein, Hiromasa Otake, Timothy J. Gundert, Bon-Kwon Koo, Toshiro Shinke, Yasuhiro Honda, Junya Shite and John F. LaDisa * Download PDF (990.7 KB) * View HTML * Permissions & Reprints * Journal Advert...
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    23. 1-24 of 39 1 2 »
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    1. (37 articles) Toshiro Shinke
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