1. Articles mentioning both Joseph A. Izatt and Duke University

    1-24 of 215 1 2 3 4 5 6 7 8 9 »
    1. Optical coherence refraction tomography

      Optical coherence refraction tomography
      Optical coherence tomography (OCT) is a cross-sectional, micrometre-scale imaging modality with widespread clinical application. Typical OCT systems sacrifice lateral resolution to achieve long depths of focus for bulk tissue imaging, and therefore tend to have better axial than lateral resolution. Such anisotropic resolution can obscure fine ultrastructural features. Furthermore, conventional OCT suffers from refraction-induced image distortions. Here, we introduce optical coherence refraction tomography (OCRT), which extends the superior axial resolution ...
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    2. Ocular anterior chamber blood cell population differentiation using spectroscopic optical coherence tomography

      Ocular anterior chamber blood cell population differentiation using spectroscopic optical coherence tomography
      There is potential clinical significance in identifying cellular responses in the anterior chamber (AC) of the eye, which can indicate hyphema (an accumulation of red blood cells [RBCs]) or aberrant intraocular inflammation (an accumulation of white blood cells [WBCs]). In this work, we developed a spectroscopic OCT analysis method to differentiate between populations of RBCs and subtypes of WBCs, including granulocytes, lymphocytes and monocytes, both in vitro and in ACs ...
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    3. Duke University Receives NIH Grant for Handheld Confocal Scanning Laser Ophthalmoscope for Remote Screening of Diabetic Retinopathy

      Duke University Receives NIH Grant for Handheld Confocal Scanning Laser Ophthalmoscope for Remote Screening of Diabetic Retinopathy
      ...er treatment of DR and potentially preventing millions of cases of blindness.

      Duke University Receives a 2019 NIH Grant for $233,465 for Handheld Confocal Scanning Laser Ophthalmoscope for...

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    4. Progress in Multimodal En Face Imaging: feature introduction

      Progress in Multimodal En Face Imaging: feature introduction
      This feature issue contains papers that report on the most recent advances in the field of en face optical coherence tomography (OCT) and of combinations of modalities facilitated by the en face view. Hardware configurations for delivery of en face OCT images are described as well as specific signal and image processing techniques tailored to deliver relevant clinical diagnoses. The value of the en face perspective for enabling multimodality is ...
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    5. Duke University Receives NIH Grant for Intrasurgical OCT Image-Guided Robot Assist Device for Partial Thickness Corneal Transplantation

      Duke University Receives NIH Grant for Intrasurgical OCT Image-Guided Robot Assist Device for Partial Thickness Corneal Transplantation
      ...oscopic 3D guidance using OCT as well as potentially other imaging techniques

      Duke University Receives a 2019 NIH Grant for $150,000 for Intrasurgical OCT Image-Guided Robot Assist Device ...

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    6. Advances in Whole-Eye Optical Coherence Tomography Imaging

      Advances in Whole-Eye Optical Coherence Tomography Imaging
      Contemporary anterior segment and retinal optical coherence tomography (OCT) systems only image their particular designated region of the eye and cannot image both areas of the eye at once. This separation is due to the differences in optical system design needed to properly image the front or back of the eye and also due to limitations in the imaging depth of current commercial OCT systems. More recently, research and commercial ...
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    7. Stereoscopic display systems and methods for displaying surgical data and information in a surgical microscope

      Stereoscopic display systems and methods for displaying surgical data and information in a surgical microscope
      Stereoscopic display systems and methods for displaying surgical data and information in a surgical microscope are disclosed herein. According to an aspect, a system includes first and second eyepieces. The system includes a display having first and second display portions, configured to display first images in the first display portion, and configured to display second images in the second display portion. The first image and the second image are projected ...
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    8. Depth-Based, Motion-Stabilized Colorization of Microscope-Integrated Optical Coherence Tomography Volumes for Microscope-Independent Microsurgery

      Depth-Based, Motion-Stabilized Colorization of Microscope-Integrated Optical Coherence Tomography Volumes for Microscope-Independent Microsurgery
      Purpose : We develop and assess the impact of depth-based, motion-stabilized colorization (color) of microscope-integrated optical coherence tomography (MIOCT) volumes on microsurgical performance and ability to interpret surgical volumes. Methods : Color was applied in real-time as gradients indicating axial position and stabilized based on calculated center of mass. In a test comparing colorization versus grayscale visualizations of prerecorded intraoperative volumes from human surgery, ophthalmologists ( N = 7) were asked to identify retinal ...
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    9. Method and system for improving aiming during optical coherence tomography on young children by synchronization with retinal bifringence scanning

      Method and system for improving aiming during optical coherence tomography on young children by synchronization with retinal bifringence scanning
      The present invention is directed to a method and system for improved aiming during Optical Coherence Tomography (OCT) on young children and those unable to cooperate with OCT imaging by synchronization with retinal birefringence scanning (RBS). OCT is performed without knowing whether or not the subject is looking at the intended target. The present invention combines OCT retinal imaging, such as, but not limited to, time domain OCT, SDOCT, or ...
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    10. Feature of the Week 06/24/2018: Duke University Researchers Show Exciting Advances in Live OCT Volumes in Immersive Virtual Reality

      Feature of the Week 06/24/2018: Duke University Researchers Show Exciting Advances in Live OCT Volumes in Immersive Virtual Reality
      Virtual reality (VR) head-mounted displays are an attractive technology for viewing intrasurgical optical coherence tomography (OCT) volumes because they liberate surgeons from microscope oculars. We demonstrate real-time, interactive viewing of OCT volumes in a commercial HTC Vive immersive VR system using previously reported ray casting techniques. Furthermore, we show interactive manipulation and sectioning of volumes using handheld controllers and guidance of mock surgical procedures in porcine eyes exclusively within VR ...
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    11. Real-time visualization and interaction with static and live optical coherence tomography volumes in immersive virtual reality

      Real-time visualization and interaction with static and live optical coherence tomography volumes in immersive virtual reality
      Virtual reality (VR) head-mounted displays are an attractive technology for viewing intrasurgical optical coherence tomography (OCT) volumes because they liberate surgeons from microscope oculars. We demonstrate real-time, interactive viewing of OCT volumes in a commercial HTC Vive immersive VR system using previously reported ray casting techniques. Furthermore, we show interactive manipulation and sectioning of volumes using handheld controllers and guidance of mock surgical procedures in porcine eyes exclusively within VR ...
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    12. Volumetric Measurement of Subretinal Blebs Using Microscope-Integrated Optical Coherence Tomography

      Volumetric Measurement of Subretinal Blebs Using Microscope-Integrated Optical Coherence Tomography
      Purpose : We advance studies of subretinal treatments by developing a microscope-integrated optical coherence tomography (MIOCT) image-based method for measuring the volume of therapeutics delivered into the subretinal space. Methods : A MIOCT image-based volume measurement method was developed and assessed for accuracy and reproducibility by imaging an object of known size in model eyes. This method then was applied to subretinal blebs created by injection of diluted triamcinolone. Bleb volumes obtained ...
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    13. Anterior chamber blood cell differentiation using spectroscopic optical coherence tomography

      Anterior chamber blood cell differentiation using spectroscopic optical coherence tomography
      There is great clinical importance in identifying cellular responses in the anterior chamber (AC) which can indicate signs of hyphema (an accumulation of red blood cells (RBCs)) or aberrant intraocular inflammation (an accumulation of white blood cells (WBCs)). These responses are difficult to diagnose and require specialized equipment such as ophthalmic microscopes and specialists trained in examining the eye. In this work, we applied spectroscopic OCT to differentiate between RBCs ...
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    14. VISUALIZATION FROM INTRAOPERATIVE SWEPT-SOURCE MICROSCOPE-INTEGRATED OPTICAL COHERENCE TOMOGRAPHY IN VITRECTOMY FOR COMPLICATIONS OF PROLIFERATIVE DIABETIC RETINOPATHY

      VISUALIZATION FROM INTRAOPERATIVE SWEPT-SOURCE MICROSCOPE-INTEGRATED OPTICAL COHERENCE TOMOGRAPHY IN VITRECTOMY FOR COMPLICATIONS OF PROLIFERATIVE DIABETIC RETINOPATHY
      Purpose: To evaluate the use of live volumetric (4D) intraoperative swept-source microscope-integrated optical coherence tomography in vitrectomy for proliferative diabetic retinopathy complications. Methods: In this prospective study, we analyzed a subgroup of patients with proliferative diabetic retinopathy complications who required vitrectomy and who were imaged by the research swept-source microscope-integrated optical coherence tomography system. In near real time, images were displayed in stereo heads-up display facilitating intraoperative surgeon feedback. Postoperative ...
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    15. Imaging of Iris Lesions With High-Speed Optical Coherence Tomography

      Imaging of Iris Lesions With High-Speed Optical Coherence Tomography
      n BACKGROUND AND OBJECTIVES:To image and measure iris tumors with optical coherence tomography (OCT). n PATIENTS AND METHODS:High-speed(2,000 4,000 axial-scan/sec and 416 frames/sec) 1.3-micron wavelength anterior segment OCT prototypes were used to image 6 eyes of 6 patients with a variety of iris lesions, including focal iris nevus, diffuse iris nevus, amelanotic iris nevus, iris melanocytosis, and iris melanoma. OCT images were ...
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    16. Statistical Models of Signal and Noise and Fundamental Limits of Segmentation Accuracy in Retinal Optical Coherence Tomography

      Statistical Models of Signal and Noise and Fundamental Limits of Segmentation Accuracy in Retinal Optical Coherence Tomography
      Optical coherence tomography (OCT) has revolutionized diagnosis and prognosis of ophthalmic diseases by visualization and measurement of retinal layers. To speed up quantitative analysis of disease biomarkers, an increasing number of automatic segmentation algorithms have been proposed to estimate the boundary locations of retinal layers. While the performance of these algorithms has significantly improved in recent years, a critical question to ask is how far we are from a theoretical ...
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    17. Characterization of Long Working Distance Optical Coherence Tomography for Imaging of Pediatric Retinal Pathology

      Characterization of Long Working Distance Optical Coherence Tomography for Imaging of Pediatric Retinal Pathology
      Purpose : We determined the feasibility of fovea and optic nerve head imaging with a long working distance (LWD) swept source optical coherence tomography (OCT) prototype in adults, teenagers, and young children. Methods : A prototype swept source OCT system with a LWD (defined as distance from the last optical element of the imaging system to the eye) of 350 mm with custom fixation targets was developed to facilitate imaging of children ...
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    18. Retinal imaging in human autopsy eyes using a custom optical coherence tomography periscope

      Retinal imaging in human autopsy eyes using a custom optical coherence tomography periscope
      Age-related macular degeneration (AMD) is a major cause of vision loss in the elderly. To better study the pathobiology of AMD, postmortem eyes offer an excellent opportunity to correlate optical coherence tomography (OCT) imaging characteristics with histopathology. However, postmortem eyes from autopsy present challenges to standard OCT imaging including opaque anterior segment structures and standard of care autopsy processing resulting in oblique views to the macula. To overcome these challenges ...
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    19. 1-24 of 215 1 2 3 4 5 6 7 8 9 »
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  2. Organizations in the News

    1. (17 articles) National Institutes of Health
    2. (7 articles) Case Western Reserve University
    3. (6 articles) Vanderbilt University
    4. (6 articles) Cleveland Clinic
    5. (5 articles) FDA
    6. (5 articles) Medical University of Vienna
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    8. (4 articles) University of Illinois at Urbana-Champaign
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    1. (69 articles) Cynthia A. Toth
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    1. (21 articles) Bioptigen
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    3. (3 articles) Axsun Technologies
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