1. Articles mentioning both Jon Holmes and Michelson Diagnostics

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    1. The vascular morphology of melanoma is related to Breslow index: an in vivo study with dynamic optical coherence tomography

      The vascular morphology of melanoma is related to Breslow index: an in vivo study with dynamic optical coherence tomography
      Background Malignant melanoma is an aggressive skin cancer, which can lead to metastasis development. Vascularization enhancement is fundamental for tumor growth, worsening the prognosis. Dynamic Optical Coherence Tomography (D‐OCT) enables the in vivo evaluation of vascular patterns in skin lesions. Objective In vivo evaluation of the melanoma vessel morphology by means of D‐OCT and correlation with Breslow index. Methods Retrospective analysis of histologically proven melanomas, evaluated by D ...
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    2. Dynamic optical coherence tomography of histamine induced wheals

      Dynamic optical coherence tomography of histamine induced wheals
      Background Dynamic optical coherence tomography (D‐OCT) is a noninvasive imaging technique providing images of the skin and detecting movement in the tissue ie, measuring blood flow. The attenuation coefficient describes light absorption and scattering abilities of the tissue, while the dynamic signal provides a quantitative measure of the blood flow. Aim The study objective is to describe the dynamic changes of the skin and skin vessels during histamine release ...
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    3. Advances in optical coherence tomography in dermatology—a review

      Advances in optical coherence tomography in dermatology—a review
      Optical coherence tomography (OCT) was introduced as an imaging system, but like ultrasonography, other measures, such as blood perfusion and polarization of light, have enabled the technology to approach clinical utility. This review aims at providing an overview of the advances in clinical research based on the improving technical aspects. OCT provides cross-sectional and en face images down to skin depths of 0.4 to 2.00 mm with optical ...
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    4. Angiographic optical coherence tomography imaging of hemangiomas and port wine birthmarks

      Angiographic optical coherence tomography imaging of hemangiomas and port wine birthmarks
      Objectives A current therapeutic challenge of vascular lesions is that they do not always respond effectively to laser treatment. Information on targeted vessels could potentially be used to guide laser treatments. Optical coherence tomography (OCT) is a useful tool for the non‐invasive imaging of tissues, including skin hemangiomas and port wine birthmarks. Dynamic OCT is able to rapidly characterize cutaneous blood vessels. The primary goal of this study was ...
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    5. Optical coherence tomography of basal cell carcinoma: influence of location, subtype, observer variability and image quality on diagnostic performance

      Optical coherence tomography of basal cell carcinoma: influence of location, subtype, observer variability and image quality on diagnostic performance
      Background We previously described the principal results from an observational, prospective, multi-centre, clinical trial of the diagnostic value of optical coherence tomography (OCT) for basal cell carcinoma (BCC) in a clinical setting. In this trial, much additional useful information was gathered that warranted further analysis, presented here. Objectives To investigate the influence of candidate diagnostic criteria, OCT image quality, lesion location, and observer confidence and inter-observer variability on the diagnostic ...
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    6. Sciton Announces Collaboration with Michelson Diagnostics Ltd. to Develop OCT Image-Guided Laser Applications

      Sciton Announces Collaboration with Michelson Diagnostics Ltd. to Develop OCT Image-Guided Laser Applications
      ...and treatments. "Optical Coherence Tomography (OCT) is a marvelous diagnostic imaging technology," says Jon Holmes, CEO of MDL. "It sees into skin deeper than one millimeter with a resolution of less than 10 micron...
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    7. Optical coherence tomography for margin definition of basal cell carcinoma before micrographic surgery—recommendations regarding the marking and scanning technique

      Optical coherence tomography for margin definition of basal cell carcinoma before micrographic surgery—recommendations regarding the marking and scanning technique
      Background/purpose Mohs Micrographic Surgery (MMS) is the preferred therapeutic treatment for high-risk basal cell carcinoma (BCC). Optical Coherence Tomography (OCT) is a non-invasive imaging technique that enables the diagnosis of BCC. We thought to determine the margins of BCCs with OCT, prior to MMS, to reduce the number of surgical steps. Methods Different permanent markers were tested on the skin regarding line width, resistance against disinfection and brightness in ...
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    8. Dynamic optical coherence tomography of skin blood vessels – proposed terminology and practical guidelines

      Dynamic optical coherence tomography of skin blood vessels – proposed terminology and practical guidelines
      Background Dynamic optical coherence tomography (D-OCT) has recently been introduced in dermatology. In contrast to Standard OCT imaging, which exclusively relies on the morphological analysis of the tissue, D-OCT allows the in-vivo visualisation of blood flow. Preliminary D-OCT data showed differences in the vascularisation of nevus to melanoma transition, suggesting that this technology may help to differentiate between benign and malignant lesions. Objective Several factors may influence the quality of ...
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    9. Adoption Depends on Meeting Clinical Needs

      Comment "This is a topic I have spoke on for decades. As a physician, OCT researcher, and co-founder of Lightlab Imaging, ..." - mebrezin
      Adoption Depends on Meeting Clinical Needs
      Every year, I am amazed and impressed by the number and variety of presentations at conferences in the field of biophotonics . We are blessed by the seemingly endless ways to manipulate and measure light, relatively inexpensively, in our pursuit of powerful new ways to understand, diagnose and treat disease. Much human ingenuity has been applied to overcoming difficult technical problems and pushing back the bounds of our knowledge. But then ...
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    10. In vivo microvascular imaging of cutaneous actinic keratosis, Bowen's disease and squamous cell carcinoma using Dynamic optical coherence tomography

      In vivo microvascular imaging of cutaneous actinic keratosis, Bowen's disease and squamous cell carcinoma using Dynamic optical coherence tomography
      Background A clear distinction between actinic keratosis (AK), Bowen's disease (BD) and squamous cell carcinoma (SCC) cannot reliably be made by clinical and dermoscopic evaluation alone. Dynamic optical coherence tomography (D-OCT) is a novel angiographic variant of OCT that allows for non-invasive, in vivo evaluation of the cutaneous microvascular morphology. Objective To investigate the microvascular structures of AK, BD and invasive SCC using D-OCT in order to gain insights ...
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    11. Vascular Features of Nail Psoriasis Using Dynamic Optical Coherence Tomography

      Vascular Features of Nail Psoriasis Using Dynamic Optical Coherence Tomography
      Background: Nail psoriasis is a painful and disfiguring nail disease that often leads to invasive biopsies. Dermoscopy of the hyponychium can be useful in the diagnosis showing twisted coiled vessels. Structural features of nail psoriasis have been described with optical coherence tomography (OCT). Objectives: To investigate vascular features of nail psoriasis using dynamic OCT. Methods: This was an observational, prospective, controlled study in which psoriasis patients with psoriatic nail changes ...
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    12. Validation of Dynamic optical coherence tomography for non-invasive, in vivo microcirculation imaging of the skin

      Validation of Dynamic optical coherence tomography for non-invasive, in vivo microcirculation imaging of the skin
      Objectives Dynamic optical coherence tomography (D-OCT) is anangiographic variation of OCT that non-invasively provides images of the in vivo microvasculature of the skin by combining conventional OCT images with flow data. The objective of this study was to investigate and report on the D-OCT technique for imaging of the vascular networks in skin as well as to validate the method by comparing the results against already accepted blood flow measuring ...
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    13. Dynamic Optical Coherence Tomography in Dermatology

      Dynamic Optical Coherence Tomography in Dermatology
      Optical coherence tomography (OCT) represents a non-invasive imaging technology, which may be applied to the diagnosis of non-melanoma skin cancer and which has recently been shown to improve the diagnostic accuracy of basal cell carcinoma. Technical developments of OCT continue to expand the applicability of OCT for different neoplastic and inflammatory skin diseases. Of these, dynamic OCT (D-OCT) based on speckle variance OCT is of special interest as it allows ...
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    14. Michelson Diagnostics launches new improved version of VivoSight OCT scanner with Micro-Camera to aid skin cancer diagnosis

      Michelson Diagnostics launches new improved version of VivoSight OCT scanner with Micro-Camera to aid skin cancer diagnosis
      ...ivalled benefit for my orientation and medical decision making ” – Dr Heckmann, Starnberg Jon Holmes, CEO of Michelson Diagnostics, added “Our VivoSight OCT scanner is already proving popular with Dermatologists who are...
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    15. 1-24 of 101 1 2 3 4 5 »
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  2. Organizations in the News

    1. (18 articles) FDA
    2. (11 articles) UK National Physical Laboratory
    3. (7 articles) University of Copenhagen
    4. (5 articles) Massachusetts Institute of Technology
    5. (5 articles) Gloucestershire Royal Hospital
    6. (5 articles) University College Hospital
    7. (3 articles) Oxford University
    8. (3 articles) Cardiff University
    9. (2 articles) University of Sheffield
    10. (1 articles) Ontario Cancer Institute
    11. (1 articles) University of Toronto
    12. (1 articles) Johannes Kepler University of Linz
  3. People in the News

    1. (10 articles) Julia Welzel
    2. (9 articles) Gregor B. E. Jemec
    3. (6 articles) Lotte Themstrup
    4. (4 articles) Gordon Mckenzie
    5. (4 articles) Barbara G. Goode
    6. (3 articles) Pete H. Tomlins
    7. (3 articles) Florian Bazant-Hegemark
    8. (3 articles) Daniel Woods
    9. (3 articles) Colin Hopper
    10. (3 articles) Wolfgang Drexler
    11. (3 articles) Daniel M. Siegel
    12. (2 articles) Nick Stone
  4. OCT Companies in the News

    1. (3 articles) Santec
    2. (2 articles) UTC Aerospace Systems
    3. (2 articles) Axsun Technologies
    4. (2 articles) Topcon Medical Systems
    5. (2 articles) Volcano Corporation
    6. (2 articles) Thorlabs
    7. (2 articles) Nidek
    8. (2 articles) Tactiq Ltd
    9. (2 articles) Kamelian Ltd.
    10. (2 articles) Optos
    11. (1 articles) Tomophase Corporation
    12. (1 articles) Carl Zeiss Meditec