1. Articles mentioning both Johannes F. de Boer and Harvard University

    1-24 of 50 1 2 »
    1. Effects of Age, Race, and Ethnicity on the Optic Nerve and Peripapillary Region Using Spectral-Domain OCT 3D Volume Scans

      Effects of Age, Race, and Ethnicity on the Optic Nerve and Peripapillary Region Using Spectral-Domain OCT 3D Volume Scans
      Purpose : To evaluate the effects of age, race, and ethnicity on the optic nerve and peripapillary retina using spectral-domain optical coherence tomography (SD-OCT) three-dimensional (3D) volume scans in normal subjects. Methods : This is a cross-sectional study performed at a single institution in Boston. All patients received retinal nerve fiber layer (RNFL) scans and an optic nerve 3D volume scan. The SD-OCT software calculated peripapillary RNFL thickness, retinal thickness (RT), and ...
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    2. Diagnostic Capability of Three-Dimensional Macular Parameters for Glaucoma Using Optical Coherence Tomography Volume Scans

      Diagnostic Capability of Three-Dimensional Macular Parameters for Glaucoma Using Optical Coherence Tomography Volume Scans
      Purpose : To compare the diagnostic capability of three-dimensional (3D) macular parameters against traditional two-dimensional (2D) retinal nerve fiber layer (RNFL) thickness using spectral domain optical coherence tomography. To determine if manual correction and interpolation of B-scans improve the ability of 3D macular parameters to diagnose glaucoma. Methods : A total of 101 open angle glaucoma patients (29 with early glaucoma) and 57 healthy subjects had peripapillary 2D RNFL thickness and 3D ...
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    3. Diagnostic Capability of Peripapillary 3D Retinal Nerve Fiber Layer Volume for Glaucoma Using Optical Coherence Tomography Volume Scans

      Diagnostic Capability of Peripapillary 3D Retinal Nerve Fiber Layer Volume for Glaucoma Using Optical Coherence Tomography Volume Scans
      Purpose To determine the diagnostic capability of peripapillary 3-dimensional (3D) retinal nerve fiber layer (RNFL) volume measurements from spectral domain optical coherence tomography (OCT) volume scans for open angle glaucoma (OAG). Design Assessment of diagnostic accuracy. Methods Setting: Academic clinical setting. Study population : 180 patients (113 OAG and 67 normal subjects). Observation procedures : One eye per subject was included. Peripapillary 3D RNFL volumes were calculated for global, quadrant, and sector ...
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    4. Introduction to the feature issue on the 25 year anniversary of optical coherence tomography

      Introduction to the feature issue on the 25 year anniversary of optical coherence tomography
      This feature issue commemorates the approximately 25 year history of Optical Coherence Tomography (OCT), one of the most successful biophotonic technologies. While OCT has technological origins traceable to ultrafast laser development and fiber optic system test instrumentation of the 1980s, innovations in low coherence interferometry for optical ranging and imaging for biomedical applications in the U.S., Europe and Japan by the early 1990s led to coinage of the now ...
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    5. Enhanced Diagnostic Capability for Glaucoma of 3-Dimensional Versus 2-Dimensional Neuroretinal Rim Parameters Using Spectral Domain Optical Coherence Tomography

      Enhanced Diagnostic Capability for Glaucoma of 3-Dimensional Versus 2-Dimensional Neuroretinal Rim Parameters Using Spectral Domain Optical Coherence Tomography
      Purpose: To compare the diagnostic capability of 3-dimensional (3D) neuroretinal rim parameters with existing 2-dimensional (2D) neuroretinal and retinal nerve fiber layer (RNFL) thickness rim parameters using spectral domain optical coherence tomography (SD-OCT) volume scans. Materials and Methods: Design: Institutional prospective pilot study. Study population: 65 subjects (35 open-angle glaucoma patients, 30 normal patients). Observation procedures: One eye of each subject was included. SD-OCT was used to obtain 2D RNFL ...
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    6. Comprehensive Three-Dimensional Analysis of the Neuroretinal Rim in Glaucoma Using High-Density Spectral-Domain Optical Coherence Tomography Volume Scans

      Comprehensive Three-Dimensional Analysis of the Neuroretinal Rim in Glaucoma Using High-Density Spectral-Domain Optical Coherence Tomography Volume Scans
      Purpose : To describe spectral-domain optical coherence tomography (OCT) methods for quantifying neuroretinal rim tissue in glaucoma and to compare these methods to the traditional retinal nerve fiber layer thickness diagnostic parameter. Methods : Neuroretinal rim parameters derived from three-dimensional (3D) volume scans were compared with the two-dimensional (2D) Spectralis retinal nerve fiber layer (RNFL) thickness scans for diagnostic capability. This study analyzed one eye per patient of 104 glaucoma patients and ...
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    7. Correlation of localized glaucomatous visual field defects and spectral domain optical coherence tomography retinal nerve fiber layer thinning using a modified structure–function map for OCT

      Correlation of localized glaucomatous visual field defects and spectral domain optical coherence tomography retinal nerve fiber layer thinning using a modified structure–function map for OCT
      Purpose To study the correlation between glaucomatous visual field (VF) defects assessed by standard automated perimetry (SAP) and peripapillary retinal nerve fiber layer (RNFL) thinning measured by spectral domain optical coherence tomography (OCT) using a modified OCT-based peripapillary RNFL structurefunction map. Patients and methods Perimetric glaucoma patients and age-matched normal control subjects were recruited from a university hospital clinic. All eyes underwent testing with the Spectralis spectral domain OCT and ...
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    8. Process, system and software arrangement for determining at least one location in a sample using an optical coherence tomography

      Process, system and software arrangement for determining at least one location in a sample using an optical coherence tomography
      A system, process and software arrangement are provided to determine at least one position of at least one portion of a sample. In particular, information associated with the portion of the sample is obtained. Such portion may be associated with an interference signal that includes a first electro-magnetic radiation received from the sample and a second electro-magnetic radiation received from a reference. In addition, depth information and/or lateral information ...
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    9. Correlation of localized glaucomatous visual field defects and spectral domain optical coherence tomography retinal nerve fiber layer thinning using a modified structure-function map for OCT

      Correlation of localized glaucomatous visual field defects and spectral domain optical coherence tomography retinal nerve fiber layer thinning using a modified structure-function map for OCT
      Purpose To study the correlation between glaucomatous visual field (VF) defects assessed by standard automated perimetry (SAP) and peripapillary retinal nerve fiber layer (RNFL) thinning measured by spectral domain optical coherence tomography (OCT) using a modified OCT-based peripapillary RNFL structurefunction map. Patients and methods Perimetric glaucoma patients and age-matched normal control subjects were recruited from a university hospital clinic. All eyes underwent testing with the Spectralis spectral domain OCT and ...
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    10. Systems, methods and computer-readable medium for determining depth-resolved physical and/or optical properties of scattering media by analyzing measured data over a range of depths

      Systems, methods and computer-readable medium for determining depth-resolved physical and/or optical properties of scattering media by analyzing measured data over a range of depths
      In depth-resolved imaging of scattering media, incident light interacts with tissue in a complex way before the signal reaches the detector: Light interacts with media between the light source and a specific depth, then scatters at that depth and the backscattered light again interacts with media on its way to the detector. The resulting depth-resolved signal therefore likely does not directly represent a physical or optical property of the media ...
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    11. In vivo imaging of human burn injuries with polarization-sensitive optical coherence tomography

      In vivo imaging of human burn injuries with polarization-sensitive optical coherence tomography
      The accurate determination of burn depth is critical in the clinical management of burn wounds. Polarization-sensitive optical coherence tomography (PS-OCT) has been proposed as a potentially non-invasive method for determining burn depth by measuring thermally induced changes in the structure and birefringence of skin, and has been investigated in pre-clinical burn studies with animal models and ex vivo human skin. In this study, we applied PS-OCT to the in-vivo imaging ...
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    12. Analysis of Normal Retinal Nerve Fiber Layer Thickness by Age, Sex, and Race Using Spectral Domain Optical Coherence Tomography

      Analysis of Normal Retinal Nerve Fiber Layer Thickness by Age, Sex, and Race Using Spectral Domain Optical Coherence Tomography
      Purpose: To determine the effects of age, sex, and race on the retinal nerve fiber layer (RNFL) in the normal human eye as measured by the spectral domain optical coherence tomography (SD-OCT) Spectralis machine (Heidelberg Engineering). Methods: Peripapillary SD-OCT RNFL thickness measurements were determined in normal subjects seen at a university-based clinic. One randomly selected eye per subject was used for analysis in this cross-sectional study. Multiple regression analysis was ...
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    13. System and method for cladding mode detection

      System and method for cladding mode detection
      According to an exemplary embodiment, systems and methods can be provided for compensating for, reducing and/or eliminating data associated with at least one aberration provided within a sample. For example, using such exemplary systems and methods, it may be possible to transmit at least one first electromagnetic radiation to the sample via an optical fiber. At least one second electromagnetic radiation can be received from the sample, and the ...
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    14. Polarization-Sensitive Optical Coherence Tomography Imaging of Benign and Malignant Laryngeal Lesions: An In Vivo Study

      Polarization-Sensitive Optical Coherence Tomography Imaging of Benign and Malignant Laryngeal Lesions: An In Vivo Study
      ... Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, USA 5Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital,...
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    15. Apparatus and method for rangings and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands

      Apparatus and method for rangings and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
      Apparatus and method for increasing the sensitivity in the detection of optical coherence tomography and low coherence interferometry ("LCI") signals by detecting a parallel set of spectral bands, each band being a unique combination of optical frequencies. The LCI broad bandwidth source is split into N spectral bands. The N spectral bands are individually detected and processed to provide an increase in the signal-to-noise ratio by a factor of N ...
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    16. Processes, arrangements and systems for providing a fiber layer thickness map based on optical coherence tomography images

      Processes, arrangements and systems for providing a fiber layer thickness map based on optical coherence tomography images
      A system, arrangement, computer-accessible medium and process are provided for determining information associated with at least one portion of an anatomical structure. For example, an interference between at least one first radiation associated with a radiation directed to the anatomical structure and at least one second radiation associated with a radiation directed to a reference can be detected. Three-dimensional volumetric data can be generated for the at least one portion ...
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    17. In vivo 3D human vocal fold imaging with polarization sensitive optical coherence tomography and a MEMS scanning catheter

      In vivo 3D human vocal fold imaging with polarization sensitive optical coherence tomography and a MEMS scanning catheter
      ...gory Pending Citation Ki Hean Kim, James A. Burns, Jonathan J. Bernstein, Gopi N. Maguluri, B. Hyle Park, and Johannes F. de Boer, "In vivo 3D human vocal fold imaging with polarization sensitive optical coherence tomogr...
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    18. Methods, arrangements and systems for polarization-sensitive optical frequency domain imaging of a sample

      Methods, arrangements and systems for polarization-sensitive optical frequency domain imaging of a sample
      Arrangements and methods are provided for obtaining data associated with a sample. For example, at least one first electro-magnetic radiation can be provided to a sample and at least one second electro-magnetic radiation can be provided to a reference (e.g., a non-reflective reference). A frequency of such radiation(s) can repetitively vary over time with a first characteristic period. In addition, a polarization state of the first electro-magnetic radiation ...
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    19. Method and apparatus for performing optical imaging using frequency-domain interferometry

      Method and apparatus for performing optical imaging using frequency-domain interferometry
      An apparatus and method are provided. In particular, at least one first electro-magnetic radiation may be provided to a sample and at least one second electro-magnetic radiation can be provided to a non-reflective reference. A frequency of the first and/or second radiations varies over time. An interference is detected between at least one third radiation associated with the first radiation and at least one fourth radiation associated with the ...
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    20. 1-24 of 50 1 2 »
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  2. Organizations in the News

    1. (44 articles) Massachusetts General Hospital
    2. (15 articles) VU University Amsterdam
    3. (12 articles) Massachusetts Eye and Ear Infirmary
    4. (7 articles) UC Riverside
    5. (3 articles) Johns Hopkins University
    6. (2 articles) University of Hong Kong
    7. (2 articles) Massachusetts Institute of Technology
    8. (1 articles) Academic Medical Center at the University of Amsterdam
    9. (1 articles) National Institutes of Health
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  3. People in the News

    1. (15 articles) Brett E. Bouma
    2. (14 articles) Teresa C. Chen
    3. (12 articles) B. Hyle Park
    4. (11 articles) Guillermo J. Tearney
    5. (9 articles) Ki Hean Kim
    6. (8 articles) Seok-Hyun Yun
    7. (5 articles) Benjamin J. Vakoc
    8. (5 articles) Mircea Mujat
    9. (4 articles) Yueli L. Chen
    10. (4 articles) Wang Yuhl Oh
    11. (3 articles) Chulmin Joo
    12. (3 articles) Daniël M. de Bruin
  4. OCT Companies in the News

    1. (2 articles) Physical Sciences Incorporated
    2. (1 articles) Heidelberg Engineering
    3. (1 articles) Carl Zeiss Meditec
    4. (1 articles) Multiwave Photonics
    5. (1 articles) Michelson Diagnostics