1. Articles mentioning both I. Alex Vitkin and Grigory V. Gelikonov

    1-17 of 17
    1. Optical coherence tomography‐based angiography device with real‐time angiography B‐scans visualization and hand‐held probe for everyday clinical use

      Optical coherence tomography‐based angiography device with real‐time angiography B‐scans visualization and hand‐held probe for everyday clinical use
      This work is dedicated to the development of the OCT system with angiography for everyday clinical use. Two major problems were solved during the development: compensation of specific natural tissue displacements, induced by contact scanning mode and physiological motion of patients (eg, respiratory and cardiac motions) and online visualization of vessel cross‐sections to provide feedback for the system operator.
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    2. Cross-Polarization Optical Coherence Tomography with Active Maintenance of the Circular Polarization of a Sounding Wave in a Common Path System

      Cross-Polarization Optical Coherence Tomography with Active Maintenance of the Circular Polarization of a Sounding Wave in a Common Path System
      We consider a cross-polarization optical coherence tomography system with a common path for the sounding and reference waves and active maintenance of the circular polarization of a sounding wave. The system is based on the formation of birefringent characteristics of the total optical path, which are equivalent to a quarter-wave plate with a 45 orientation of its optical axes with respect to the linearly polarized reference wave. Conditions under which ...
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    3. Quantitative Cross-Polarization Optical Coherence Tomography Detection of Infiltrative Tumor Margin in a Rat Glioma Model: a Pilot Study

      Quantitative Cross-Polarization Optical Coherence Tomography Detection of Infiltrative Tumor Margin in a Rat Glioma Model: a Pilot Study
      Determining boundaries of infiltrative glial tumors remains a challenging problem in neurooncology. Optical coherence tomography (OCT) with cross-polarization (CP) visualization is a promising technique as a surgical guidance tool. However, the outcome of the procedures performed under OCT guidance strongly depends on the surgeons qualification. Thus, a quantitative method for assessing resection margins with OCT is required. The aim of this study was to develop a robust quantitative approach for ...
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    4. In-vivo longitudinal imaging of microvascular changes in irradiated oral mucosa of radiotherapy cancer patients using optical coherence tomography

      In-vivo longitudinal imaging of microvascular changes in irradiated oral mucosa of radiotherapy cancer patients using optical coherence tomography
      Mucositis is the limiting toxicity of radio(chemo)therapy of head and neck cancer. Diagnostics, prophylaxis and correction of this condition demand new accurate and objective approaches. Here we report on an in vivo longitudinal monitoring of the oral mucosa dynamics in 25 patients during the course of radiotherapy of oropharyngeal and nasopharyngeal cancer using multifunctional optical coherence tomography (OCT). A spectral domain OCT system with a specially-designed oral imaging ...
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    5. Pixel classification method in optical coherence tomography for tumor segmentation and its complementary usage with OCT microangiography

      Pixel classification method in optical coherence tomography for tumor segmentation and its complementary usage with OCT microangiography
      A novel machine-learning method to distinguish between tumor and normal tissue in optical coherence tomography (OCT) has been developed. Pre-clinical murine ear model implanted with mouse colon carcinoma CT-26 was used. Structural-image-based feature sets were defined for each pixel and machine learning classifiers were trained using ground truth OCT images manually segmented by comparison with histology. The accuracy of the OCT tumour segmentation method was then quantified by comparing with ...
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    6. Optical coherence elastography for strain dynamics measurements in laser correction of cornea shape

      Optical coherence elastography for strain dynamics measurements in laser correction of cornea shape
      We describe the use of elastographic processing in phase-sensitive optical coherence tomography (OCT) for visualizing dynamics of strain and tissue-shape changes during laser-induced photothermal corneal reshaping, for applications in the emerging field of non-destructive and non-ablative (non-LASIK) laser vision correction. The proposed phase-processing approach based on fairly sparse data acquisition enabled rapid data processing and near-real-time visualization of dynamic strains. The approach avoids conventional phase unwrapping, yet allows for mapping ...
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    7. Multiparameter thermo-mechanical OCT-based characterization of laser-induced cornea reshaping

      Multiparameter thermo-mechanical OCT-based characterization of laser-induced cornea reshaping
      Phase-sensitive optical coherence tomography (OCT) is used for visualizing dynamic and cumulative strains and corneashape changes during laser-produced tissue heating. Such non-destructive (non-ablative) cornea reshaping can be used as a basis of emerging technologies of laser vision correction. In experiments with cartilaginous samples, polyacrilamide phantoms and excised rabbit eyes we demonstrate ability of the developed OCT system to simultaneously characterize transient and cumulated strain distributions, surface displacements, scattering tissue properties ...
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    8. Vessel-contrast enhancement in label-free optical coherence angiography based on phase and amplitude speckle variability

      Vessel-contrast enhancement in label-free optical coherence angiography based on phase and amplitude speckle variability
      Recently proposed in vivo label-free optical coherence angiography techniques based on phase and amplitude speckle variability often require additional signal pre- and post processing operations to enhance vessel-contrast. We observe here 1) contrast enhancement by optimizing the signal normalization/weighing before processing; 2) algorithm based on Kasai estimator for phase compensation between processed A-scans to reduce masking role of motion artifacts; and 3) image projection through the imaging depth for ...
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    9. Robust strain mapping in optical coherence elastography by combining local phase-resolved measurements and cumulative displacement tracking

      Robust strain mapping in optical coherence elastography by combining local phase-resolved measurements and cumulative displacement tracking
      We report a novel hybrid method of robust strain mapping in compressional optical coherence elastography using combined phase measurements on sub-wavelength-scale and cumulative pixel-scale displacement tracking. This hybrid nature significantly extends the range of measurable displacements and strains in comparison with conventional direct phase-resolved measurements. As a result, the proposed strain-mapping method exhibits significantly increased robustness with respect to both additive noise and decorrelation noise produced by displacements and strains ...
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    10. Characterization of atherosclerotic plaques by cross-polarization optical coherence tomography

      Characterization of atherosclerotic plaques by cross-polarization optical coherence tomography
      We combined cross-polarization optical coherence tomography (CP OCT) and non-linear microscopy based on second harmonic generation (SHG) and two-photon-excited fluorescence (2PEF) to assess collagen and elastin fibers in the development of the atherosclerotic plaque (AP). The study shows potential of CP OCT for the assessment of collagen and elastin fibers condition in atherosclerotic arteries. Specifically, the additional information afforded by CP OCT, related to birefringence and cross-scattering properties of arterial ...
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    11. Multi-modal optical imaging characterization of atherosclerotic plaques

      Multi-modal optical imaging characterization of atherosclerotic plaques
      We combined cross-polarization optical coherence tomography (CP OCT) and non-linear microscopy based on second harmonic generation (SHG) and two-photon-excited fluorescence (2PEF) to assess collagen and elastin fibers and other vascular structures in the development of atherosclerosis, including identification of vulnerable plaques, which remains an important clinical problem and imaging application. CP OCT's ability to visualize tissue birefringence and cross-scattering adds new information about the microstructure and composition of the ...
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    12. Deformation-induced speckle-pattern evolution and feasibility of correlational speckle tracking in optical coherence elastography

      Deformation-induced speckle-pattern evolution and feasibility of correlational speckle tracking in optical coherence elastography
      Feasibility of speckle tracking in optical coherence tomography (OCT) based on digital image correlation (DIC) is discussed in the context of elastography problems. Specifics of applying DIC methods to OCT, compared to processing of photographic images in mechanical engineering applications, are emphasized and main complications are pointed out. Analytical arguments are augmented by accurate numerical simulations of OCT speckle patterns. In contrast to DIC processing for displacement and strain estimation ...
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    13. The Development of the Methodology of Monitoring Experimental Tumors Using Multimodal Optical Coherence Tomography: the Choice of an Optimal Tumor Model

      The Development of the Methodology of Monitoring Experimental Tumors Using Multimodal Optical Coherence Tomography: the Choice of an Optimal Tumor Model
      The objective of the research was to study the features of transplantation, growth and visualization of experimental tumors of animals, using multi-functional optical coherence tomography (OCT) to develop the methodology of evaluation of individual tumor response to anti-cancer therapy. Materials and Methods. The research was carried out using an experimental high-speed spectral-domain multimodal OCT system developed at the Institute of Applied Physics of the Russian Academy of Sciences (Russia). The ...
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    14. Scan-pattern and signal processing for microvasculature visualization with complex SD-OCT: tissue-motion artifacts robustness and decorrelation time - blood vessel characteristics

      Scan-pattern and signal processing for microvasculature visualization with complex SD-OCT: tissue-motion artifacts robustness and decorrelation time - blood vessel characteristics
      ...xandr L. Matveyev ; Alexander A. Moiseev ; Sergey Y. Ksenofontov ; Valentin M. Gelikonov ; Valentin Demidov ; Alex Vitkin; Scan-pattern and signal processing for microvasculature visualization with complex SD-OCT: tissue...
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    15. Hybrid M-mode-like OCT imaging of 3D microvasculature in vivo using reference-free processing of complex-valued B-scans

      Hybrid M-mode-like OCT imaging of 3D  microvasculature in vivo using reference-free  processing of complex-valued B-scans
      We propose a novel OCT-based method for visualizing microvasculature in 3D using reference-free processing of individual complex-valued B-scans with highly overlapped A-scans. In the lateral direction of such a B-scan, the amplitude and phase of speckles corresponding to vessel regions exhibit faster variability, and thus can be detected without comparison with other B-scans recorded in the same plane. This method combines elements of several existing OCT angiographic approaches, and exhibits ...
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    16. Recent Trends in Multimodal Optical Coherence Tomography. II. The Correlation-Stability Approach in OCT Elastography and Methods for Visualization of Microcirculation

      Recent Trends in Multimodal Optical Coherence Tomography. II. The Correlation-Stability Approach in OCT Elastography and Methods for Visualization of Microcirculation
      ...ess, 13, 5234 (2005). J. W. Goodman, Statistical Optics, Wiley, New York (2000). L. Conroy, R. DaCosta, and I. A. Vitkin, Opt. Lett., 37, 3180 (2012). B. Davoudi, M. Morrison, K. Bizheva, et al., J. Biomed. Opt., 18, ...
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    17. Optical Coherence Tomography Used $500M of Federally Funded Research Over The Past Decade: How was it Used, What was Accomplished, and What’s to Come?

      Optical Coherence Tomography Used $500M of Federally Funded Research Over The Past Decade: How was it Used, What was Accomplished, and What’s to Come?
      ...echnology development (not mainly OCT) but in keeping with the original search criterion they were included.  Alex Vitkin, Victor Yang, Marinko Saurnic, Kostadinka Bizheva, Thomas Tiedje, and Brian Wilson are the top 6 C...
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      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Organizations in the News

    1. (16 articles) University of Toronto
    2. (15 articles) Nizhny Novgorod State Medical Academy
    3. (13 articles) Institute of Applied Physics
    4. (3 articles) Ontario Cancer Institute
    5. (1 articles) Technical University of Denmark (DTU)
    6. (1 articles) UC Irvine
    7. (1 articles) University of Illinois at Urbana-Champaign
    8. (1 articles) Massachusetts Institute of Technology
    9. (1 articles) UCLA
    10. (1 articles) National Institutes of Health
    11. (1 articles) VU University Amsterdam
    12. (1 articles) University of Pittsburgh
  3. People in the News

    1. (10 articles) Valentin M. Gelikonov
    2. (9 articles) Natalia D. Gladkova
    3. (6 articles) Elena B. Kiseleva
    4. (4 articles) Felix I. Feldchtein
    5. (4 articles) Elena V. Zagaynova
    6. (2 articles) Maria M. Karabut
    7. (1 articles) Guillermo J. Tearney
    8. (1 articles) Ralph P. Tatam
    9. (1 articles) Joseph A. Izatt
    10. (1 articles) Claude Boccara
    11. (1 articles) Alexander M. Sergeev
    12. (1 articles) Brian C. Wilson
  4. OCT Companies in the News

    1. (1 articles) Lantis Laser
    2. (1 articles) Carl Zeiss Meditec
    3. (1 articles) Avinger
    4. (1 articles) UTC Aerospace Systems
    5. (1 articles) Oncoscope
    6. (1 articles) Tomophase Corporation
    7. (1 articles) Heliotis AG
    8. (1 articles) Imalux
    9. (1 articles) Optopol Technology
    10. (1 articles) OCT Medical Imaging Inc
    11. (1 articles) Nexus Imaging Systems
    12. (1 articles) OptiMedica