1. Articles mentioning both Giulio Guagliumi and Ospedali Riuniti di Bergamo

    1-24 of 40 1 2 »
    1. Deep neural networks for A-line-based plaque classification in coronary intravascular optical coherence tomography images

      Deep neural networks for A-line-based plaque classification in coronary intravascular optical coherence tomography images
      We develop neural-network-based methods for classifying plaque types in clinical intravascular optical coherence tomography (IVOCT) images of coronary arteries. A single IVOCT pullback can consist of 500 microscopic-resolution images, creating both a challenge for physician interpretation during an interventional procedure and an opportunity for automated analysis. In the proposed method, we classify each A-line, a datum element that better captures physics and pathophysiology than a voxel, as a fibrous layer ...
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    2. Pre-infarction Angina and Culprit Lesion Morphologies in Patients with a First ST-segment Elevation Acute Myocardial Infarction: Insights from In Vivo Optical Coherence Tomography

      Pre-infarction Angina and Culprit Lesion Morphologies in Patients with a First ST-segment Elevation Acute Myocardial Infarction: Insights from In Vivo Optical Coherence Tomography
      Aims: This study aimed to evaluate the relationship between pre-infarction angina (PIA) and in vivo culprit lesion characteristics as assessed by intravascular optical coherence tomography (OCT) in patients with a first ST-segment elevation myocardial infarction (STEMI). Methods and results: A total of 305 consecutive patients with a first STEMI who underwent OCT imaging of culprit lesions during primary percutaneous coronary intervention (PCI) were prospectively enrolled. OCT findings of the culprit ...
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    3. Intracoronary optical coherence tomography: Clinical and research applications and intravascular imaging software overview

      Intracoronary optical coherence tomography: Clinical and research applications and intravascular imaging software overview
      By providing valuable information about the coronary artery wall and lumen, intravascular imaging may aid in optimizing interventional procedure results and thereby could improve clinical outcomes following percutaneous coronary intervention (PCI). Intravascular optical coherence tomography (OCT) is a light-based technology with a tissue penetration of approximately 1 to 3 mm and provides near histological resolution. It has emerged as a technological breakthrough in intravascular imaging with multiple clinical and research ...
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    4. Optical coherence tomography evaluation of intermediate-term healing of different stent types: systemic review and meta-analysis

      Optical coherence tomography evaluation of intermediate-term healing of different stent types: systemic review and meta-analysis
      Aims The intermediate-term incidence of strut malapposition (SM) and uncovered struts (US), and the degree of neointimal thickness (NIT) according to stent type have not been characterized. Methods and results All studies of 50 patients in which optical coherence tomography was performed between 6 and 12 months after stent implantation were included. The incidences of SM and US were the co-primary end points, while NIT was the secondary end point ...
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    5. Optical coherence tomography versus intravascular ultrasound to evaluate coronary artery disease and percutaneous coronary intervention

      Optical coherence tomography versus intravascular ultrasound to evaluate coronary artery disease and percutaneous coronary intervention
      ...ter, Case Western Reserve University, Cleveland, Ohio * ^† Division of Cardiology, Cardiovascular Department, Ospedali Riuniti di Bergamo, Bergamo, Italy * ^‡ Department of Cardiology, New Tokyo Hospital, Chiba, Japan * ...
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    6. Volumetric assessment of lesion severity with optical coherence tomography: relationship with fractional flow reserve

      Volumetric assessment of lesion severity with optical coherence tomography: relationship with fractional flow reserve
      Aims: Frequency-domain optical coherence tomography (FD-OCT) provides a rapid tomographic scan of a coronary vessel, with an accurate reconstruction of its lumen profile. An FD-OCT-based metric that corresponds more closely with physiological significance of lesions may enable more precise guidance of interventional procedures. The aim of this feasibility study was to evaluate a new method for quantifying coronary lesion severity that estimates hyperaemic flow resistance of branched vessel segments imaged ...
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    7. Expert review document part 2: methodology, terminology and clinical applications of optical coherence tomography for the assessment of interventional procedures

      Expert review document part 2: methodology, terminology and clinical applications of optical coherence tomography for the assessment of interventional procedures
      Introduction This document is complementary to an Expert Review Document on Optical Coherence Tomography (OCT) for the study of coronary arteries and atherosclerosis.1 The goal of this companion manuscript is to provide a practical guide framework for the appropriate use and reporting of the novel frequency domain (FD) OCT imaging to guide interventional procedures, with a particular interest on the comparison with intravascular ultrasound (IVUS).1–4 Technique for ...
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    8. Impact of different stent alloys on human vascular response to everolimus-eluting stent. An optical coherence tomography study. The OCTEVEREST

      Impact of different stent alloys on human vascular response to everolimus-eluting stent. An optical coherence tomography study. The OCTEVEREST
      ...Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH, US *Cardiovascular Department, Ospedali Riuniti di Bergamo, Largo Barozzi 1, 24128 Bergamo ITALY percutaneous coronary intervention; drug-elu...
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    9. Serial Assessment of Coronary Artery Response to Paclitaxel-Eluting Stents Using Optical Coherence Tomography

      Serial Assessment of Coronary Artery Response to Paclitaxel-Eluting Stents Using Optical Coherence Tomography
      Background—The paucity of longitudinal, serial high-resolution imaging studies has limited our understanding of in vivo arterial response to drug-eluting stents. We sought to investigate the human coronary response to paclitaxel-eluting stent implantation, using serial optical coherence tomography assessments. Methods and Results—Thirty patients with at least 2 significant coronary lesions in different vessels were treated with a paclitaxel-eluting stent. The most severe stenosis (lesion A) was treated at the ...
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    10. Examination of the In Vivo Mechanisms of Late Drug-Eluting Stent Thrombosis: Findings From Optical Coherence Tomography and Intravascular Ultrasound Imaging

      Examination of the In Vivo Mechanisms of Late Drug-Eluting Stent Thrombosis: Findings From Optical Coherence Tomography and Intravascular Ultrasound Imaging
      ...n, New York, New York * Reprint requests and correspondence: Dr. Giulio Guagliumi, Cardiovascular Department, Ospedali Riuniti di Bergamo, Largo Barozzi 1, Ingresso 14, 24121 Bergamo, Italy (Email: Objectives: This study...
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    11. Impact of Drug Release Kinetics on Vascular Response to Different Zotarolimus-Eluting Stents Implanted in Patients With Long Coronary Stenoses: The LongOCT Study (Optical Coherence Tomography in Long Lesions)

      Impact of Drug Release Kinetics on Vascular Response to Different Zotarolimus-Eluting Stents Implanted in Patients With Long Coronary Stenoses: The LongOCT Study (Optical Coherence Tomography in Long Lesions)
      ...sity, Cleveland, Ohio * Reprint requests and correspondence: Dr. Giulio Guagliumi, Cardiovascular Department, Ospedali Riuniti di Bergamo, Largo Barozzi 1, 24128 Bergamo, Italy (Email: Objectives: We assessed the in vivo...
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    12. The impact of an eccentric intravascular ImageWire during coronary optical coherence tomography imaging

      The impact of an eccentric intravascular ImageWire during coronary optical coherence tomography imaging
      Optical Coherence Tomography (OCT) provides high-resolution imaging which enables characterisation of atherosclerosis and vascular response to injury, but to ensure optimal analysis, one must realise potential sources of image distortion. We designed a series of analysesl, using coronary stents as a model, to investigate the influence of wire position on OCT-derived vascular images.
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    13. Strut Coverage and Late Malapposition With Paclitaxel-Eluting Stents Compared With Bare Metal Stents in Acute Myocardial Infarction: OCT Substudy of the Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI)

      Strut Coverage and Late Malapposition With Paclitaxel-Eluting Stents Compared With Bare Metal Stents in Acute Myocardial Infarction: OCT Substudy of the Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI)
      ...M., G.W.S.). Correspondence to Giulio Guagliumi, MD, FESC, Division of Cardiology, Cardiovascular Department, Ospedali Riuniti di Bergamo, Largo Barozzi 1, Ingresso 14, 24121 Bergamo, Italy. E-mail Background— The safety...
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    14. Optical coherence tomography in ST-elevation myocardial infarction treated with novel drug-eluting stent: preprocedural, post implant and 2-month follow-up findings

      Optical coherence tomography in ST-elevation myocardial infarction treated with novel drug-eluting stent: preprocedural, post implant and 2-month follow-up findings
      The use of drug-eluting stents (DES) allowed the reduction in the need for repeat revascularization. At the culprit site in acute myocardial infarction patients treated with first-generation DES, the interaction between the eluted drug and the underlying necrotic core may generate different patterns of pathologic vessel response and delayed healing. A new generation DES intrepide elutes trapidil. Its modes of action are neither cytotoxic nor cytostatic, and may promote normal ...
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    15. Angiographic, IVUS and OCT evaluation of the long-term impact of coronary disease severity at the site of overlapping drug-eluting and bare metal stents: a substudy of the ODESSA trial

      Angiographic, IVUS and OCT evaluation of the long-term impact of coronary disease severity at the site of overlapping drug-eluting and bare metal stents: a substudy of the ODESSA trial
      ...pitals Case Medical Centre and Case Western Reserve University, Cleveland, Ohio, USA 2. ^2Azienda Ospedaliera Ospedali Riuniti di Bergamo, Bergamo, Italy 1. Correspondence to Dr Marco A Costa, Harrington McLaughlin Heart...
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    16. Strut Coverage and Vessel Wall Response to a New-Generation Paclitaxel-Eluting Stent With an Ultrathin Biodegradable Abluminal Polymer: Optical Coherence Tomography Drug-Eluting Stent Investigation (OCTDESI)

      Strut Coverage and Vessel Wall Response to a New-Generation Paclitaxel-Eluting Stent With an Ultrathin Biodegradable Abluminal Polymer: Optical Coherence Tomography Drug-Eluting Stent Investigation (OCTDESI)
      ...orporation (D.J.A., K.D.D.), Natick, Mass. Correspondence to Giulio Guagliumi, MD, Interventional Cardiology, Ospedali Riuniti di Bergamo, Largo Barozzi n. 1 - Ingresso 14, 24128 Bergamo, Italy. E-mail Background—Polymer...
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    17. Strut Coverage and Vessel Wall Response to Zotarolimus-Eluting and Bare-Metal Stents Implanted in Patients With ST-Segment Elevation Myocardial Infarction: The Octami (Optical Coherence Tomography in Acute Myocardial Infarction) Study

      Strut Coverage and Vessel Wall Response to Zotarolimus-Eluting and Bare-Metal Stents Implanted in Patients With ST-Segment Elevation Myocardial Infarction: The Octami (Optical Coherence Tomography in Acute Myocardial Infarction) Study
      ...sity, Cleveland, Ohio * Reprint requests and correspondence: Dr. Giulio Guagliumi, Cardiovascular Department, Ospedali Riuniti di Bergamo, Largo Barozzi 1, 24128 Bergamo, Italy (Email: Objectives: Using optical coherence...
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    18. Advanced intracoronary imaging: from theory to practice (Slide Show and Video Lecture from PCR 2010)

      Advanced intracoronary imaging: from theory to practice (Slide Show and Video Lecture from PCR 2010)
      Video and Slide Lecture on OCT in Cardiology. Chapters include: Optical coherence tomography: the basics, Live demonstration from Milan, Optical coherence tomography in acute coronary syndromes, Optical coherence tomography for optimal stent implantation, Recorded case (from Washington), Optical coherence tomography and other invasive imaging techniques, Take-home message. To understand how to perform and read optical coherence tomography To understand its usefulness in managing acute coronary syndrome patients To learn to ...
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    19. Optical coherence tomography (OCT) strut-level analysis of drug-eluting stents (DES) in human coronary bifurcations

      Optical coherence tomography (OCT) strut-level analysis of drug-eluting stents (DES) in human coronary bifurcations
      Aims: We sought to evaluate the vascular response of stent struts deployed in bifurcation segments using optical coherence tomography (OCT). Conclusions: This study demonstrates a variable patter of strut coverage in the bifurcation among stent technologies, with a high percentage of PES floating struts remaining uncovered at 6-month follow-up.
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    20. Optical Coherence Tomography Assessment of In Vivo Vascular Response After Implantation of Overlapping Bare-Metal and Drug-Eluting Stents

      Optical Coherence Tomography Assessment of In Vivo Vascular Response After Implantation of Overlapping Bare-Metal and Drug-Eluting Stents
      ...y of Turin, Turin, Italy * Reprint requests and correspondence: Dr. Giulio Guagliumi, Division of Cardiology, Ospedali Riuniti di Bergamo, Largo Barozzi 1, 24121 Bergamo, Italy (Email: Objectives: We designed a randomize...
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    1. (23 articles) Case Western Reserve University
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    1. (19 articles) Giuseppe Musumeci
    2. (18 articles) Vasile Sirbu
    3. (18 articles) Marco A. Costa
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