1. Articles mentioning both Evelyn Regar and Gijs van Soest

    1-24 of 33 1 2 »
    1. Intravascular imaging for characterization of coronary atherosclerosis

      Intravascular imaging for characterization of coronary atherosclerosis
      This short review surveys recent developments in coronary intravascular imaging technologies. We present an outline of the applications of intravascular imaging for guidance of percutaneous coronary interventions and imaging of atherosclerosis, along with emerging clinical evidence for use. Imaging of tissue composition is important for understanding the relation between the presence of a lesion and clinical sequelae. We describe the recent innovations to enable imaging of unstable atherosclerotic plaques, focusing ...
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    2. EuroIntervention Automated characterisation of lipid core plaques in vivo by quantitative optical coherence tomography tissue type imaging

      EuroIntervention Automated characterisation of lipid core plaques in vivo by quantitative optical coherence tomography tissue type imaging
      Aims: Qualitative criteria for plaque tissue characterisation by OCT are well established, but quantitative methods lack systematic validation in vivo . High optical attenuation coefficient t has been associated with unstable plaque features, such as lipid core. The purpose of this study was to validate optical coherence tomography (OCT) attenuation imaging for tissue characterisation in vivo , specifically to detect lipid core in coronary atherosclerotic plaques, and to evaluate quantitatively the ability ...
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    3. Optical coherence tomography attenuation imaging for lipid core detection: an ex-vivo validation study

      Optical coherence tomography attenuation imaging for lipid core detection: an ex-vivo validation study
      Lipid-core atherosclerotic plaques are associated with disease progression, procedural complications, and cardiac events. Coronary plaque lipid can be quantified in optical coherence tomography (OCT) pullbacks by measurement of lipid arcs and lipid lengths; parameters frequently used in clinical research, but labor intensive and subjective to analyse. In this study, we investigated the ability of quantitative attenuation, derived from intravascular OCT, to detect plaque lipid. Lipid cores are associated with a ...
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    4. Heartbeat OCT and Motion-Free 3D In Vivo Coronary Artery Microscopy

      Heartbeat OCT and Motion-Free 3D In Vivo Coronary Artery Microscopy
      Intravascular optical coherence tomography (IV-OCT) has gained widespread use over the past few years, offering highly detailed images of coronary artery pathologies and interventions (1) . In contrast to the cross-sectional view, longitudinal sections and 3-dimensional (3D) renderings are affected by cardiac motion artifacts and undersampling, complicating interpretation and measurements (2) . We developed Heartbeat OCT, a new OCT method that achieves up to 4,000 frames/s imaging speed for isotropically ...
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    5. Safety of optical coherence tomography in daily practice: a comparison with intravascular ultrasound

      Safety of optical coherence tomography in daily practice: a comparison with intravascular ultrasound
      Aims Previous studies have reported the safety and feasibility of both time-domain optical coherence tomography (TD-OCT) and Fourier-domain OCT (FD-OCT) in highly selected patients and clinical settings. However, the generalizability of these data is limited, and data in unselected patient populations reflecting a routine cathlab practice are lacking. We compared safety of intracoronary FD-OCT imaging to intravascular ultrasound (IVUS) imaging in a large real-world series of consecutive patients who underwent ...
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    6. Feature Of The Week 12/06/2015: Heartbeat Optical Coherence Tomography

      Feature Of The Week 12/06/2015: Heartbeat Optical Coherence Tomography
      Intravascular optical coherence tomography (IV-OCT) has gained widespread use over the past few years, offering highly detailed images of the coronary artery pathologies and interventions. In contrast to the cross-sectional view, longitudinal sections and three-dimensional (3D) renderings are affected by cardiac motion artifacts and undersampling, complicating interpretation and measurements. We developed Heartbeat OCT, a new OCT method that overcomes these issues. This study aims to demonstrate in vivo Heartbeat OCT ...
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    7. Quantification of fibrous cap thickness in intracoronary optical coherence tomography with a contour segmentation method based on dynamic programming

      Quantification of fibrous cap thickness in intracoronary optical coherence tomography with a contour segmentation method based on dynamic programming
      Objectives Fibrous cap thickness is the most critical component of plaque stability. Therefore, in vivo quantification of cap thickness could yield valuable information for estimating the risk of plaque rupture. In the context of preoperative planning and perioperative decision making, intracoronary optical coherence tomography imaging can provide a very detailed characterization of the arterial wall structure. However, visual interpretation of the images is laborious, subject to variability, and therefore not ...
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    8. OCT Assessment of the Long-Term Vascular Healing Response 5 Years After Everolimus-Eluting Bioresorbable Vascular Scaffold

      OCT Assessment of the Long-Term Vascular Healing Response 5 Years After Everolimus-Eluting Bioresorbable Vascular Scaffold
      Background Although recent observations suggest a favorable initial healing process of the everolimus-eluting bioresorbable vascular scaffold (BVS), little is known regarding long-term healing response. Objectives This study assessed the in vivo vascular healing response using optical coherence tomography (OCT) 5 years after elective first-in-man BVS implantation. Methods Of the 14 living patients enrolled in the Thoraxcenter Rotterdam cohort of the ABSORB A study, 8 patients underwent invasive follow-up, including OCT ...
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    9. Effect of temperature and fixation on the optical properties of atherosclerotic tissue: a validation study of an ex-vivo whole heart cadaveric model

      Effect of temperature and fixation on the optical properties of atherosclerotic tissue: a validation study of an ex-vivo whole heart cadaveric model
      ... Gijs van Soest, Stephen White, Simon Scoltock, Giovanni J Ughi, Andreas Baumbach, Antonius FW van der Steen, Evelyn Regar, and Thomas W Johnson »View Author Affiliations Muthukaruppan Gnanadesigan,^1,^* Gijs van Soest,...
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    10. Association of neointimal morphology by optical coherence tomography with rupture of neoatherosclerotic plaque very late after coronary stent implantation.

      Association of neointimal morphology by optical coherence tomography with rupture of neoatherosclerotic plaque very late after coronary stent implantation.
      ...uzas ; Joost Daemen ; Gijs van Soest ; Muthukaruppan Gnanadesigan ; Robert-Jan van Geuns ; Peter de Jaegere ; Evelyn Regar; Association of neointimal morphology by optical coherence tomography with rupture of neoatherosc...
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    11. In-stent neoatherosclerosis: are first generation drug eluting stents different than bare metal stents? an optical coherence tomography study

      In-stent neoatherosclerosis: are first generation drug eluting stents different than bare metal stents? an optical coherence tomography study
      ...touzas ; Joost Daemen ; Gijs van Soest ; Muthukaruppan Gnanadesigan ; Nicholas van Mieghem ; Felix Zijlstra ; Evelyn Regar; In-stent neoatherosclerosis: are first generation drug eluting stents different than bare metal ...
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    12. Frequency domain multiplexing for speckle reduction in optical coherence tomography

      Frequency domain multiplexing for speckle reduction in optical coherence tomography
      Quantitative analysis of optical coherence tomography data can be strongly hampered by speckle. Here, we introduce a new method to reduce speckle, which leverages from Fourier-domain configurations and operates on individual axial scans. By subdividing the digitized spectrum into a number of distinct narrower windows, each with a different center frequency, several independent speckle patterns result. These can be averaged to yield a lower-resolution image with strongly reduced speckle. The ...
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    13. Interstudy reproducibility of the second generation, Fourier domain optical coherence tomography in patients with coronary artery disease and comparison with intravascular ultrasound: a study applying automated contour detection

      Interstudy reproducibility of the second generation, Fourier domain optical coherence tomography in patients with coronary artery disease and comparison with intravascular ultrasound: a study applying automated contour detection
      ...ascular ultrasound: a study applying automated contour detection Z. Jamil, G. Tearney, N. Bruining, K. Sihan, G. van Soest, J. Ligthart, R. van Domburg, B. Bouma and E. Regar * Download PDF (1.3 MB) * View HTML * Permiss...
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    14. Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation

      Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation
      ...ovanni J. Ughi, PhD, Heleen M.M. van Beusekom, PhD, Antonius F.W. van der Steen, PhD, Gerrit-Ann van Es, PhD, Gijs van Soest, PhD, Renu Virmani, MD, Sergio Waxman, MD, Neil J. Weissman, MD and Giora Weisz, MD * The Massa...
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    15. Wavelength multiplexing for FD-OCT speckle averaging

      Wavelength multiplexing for FD-OCT speckle averaging
      Quantitative analysis of OCT data can be strongly hampered by speckle. We propose a new method to reduce speckle, operating on a single Fourier-domain optical coherence tomography (FD-OCT) A-line. The full acquired spectrum is used for image generation, exhibiting fully developed speckle. By subdividing the same acquired spectrum in a number of distinct narrower windows, each with a different center frequency, several independent speckles can be generated. These can be ...
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    16. Witnessed Coronary Plaque Rupture During Cardiac Catheterization

      Witnessed Coronary Plaque Rupture During Cardiac Catheterization
      Acute myocardial infarction is primarily caused by atherosclerotic plaque rupture within coronary arteries accompanied by intraluminal thrombus formation, sudden vessel occlusion, and impaired oxygen supply to the myocardium. However, study of plaque rupture has been previously limited to histological analysis of autopsy specimens and animal experiments. Using a high-resolution imaging technique, called intracoronary optical frequency domain imaging (OFDI), we have directly observed the microstructural detail of human coronary plaque rupture ...
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    17. 1-24 of 33 1 2 »
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  2. Organizations in the News

    1. (32 articles) Erasmus University
    2. (8 articles) Massachusetts General Hospital
    3. (7 articles) Harvard University
    4. (4 articles) Delft University of Technology
    5. (2 articles) University of Lübeck
    6. (2 articles) Academic Medical Center at the University of Amsterdam
    7. (2 articles) Ludwig Maximilian University of Munich
    8. (2 articles) University of Melbourne
    9. (2 articles) Leiden University
    10. (2 articles) Chinese Academy of Sciences
    11. (1 articles) Massachusetts Institute of Technology
    12. (1 articles) K. U. Leuven
  3. People in the News

    1. (14 articles) Anton F. W. van der Steen
    2. (12 articles) Patrick W. Serruys
    3. (10 articles) Jurgen M. Ligthart
    4. (9 articles) Nieves Gonzalo
    5. (8 articles) Nico Bruining
    6. (7 articles) Brett E. Bouma
    7. (7 articles) Antonios Karanasos
    8. (6 articles) Guillermo J. Tearney
    9. (6 articles) Hector M. Garcia-Garcia
    10. (5 articles) Heleen M. M. Van Beusekom
    11. (5 articles) Karen T. Witberg
    12. (5 articles) Takayuki Okamura
  4. OCT Companies in the News

    1. (9 articles) St. Jude Medical
    2. (1 articles) Optores